XLOC_025246 (pde6ga)


Basic Information

Item Value
gene id XLOC_025246
gene name pde6ga
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 19460991 ~ 19466015 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00049858
ATCGACAGGCGTATAAGAGCAGAGTGTGTGTTTCCAGAGAGCAGCATCTTTACCAGCGCAGACAAAAGACCAGCAGGTCATCATCAAATCATCACTTTACTCCATCGGTCTCCTCGTAAATATGGATGTTTCCAAGCCTAAATCGACCAGCAAAGGTGCCACACGTGCCACAGGACCTGGCAGTCCCCACAAGGGCCCACCTAAGTTCAAACAGAGGTCAACACGCCAGTTTAAGAGCAAACCACCCAAAAAGGGTGTCATCGGatttgGTGAAGAGATTCCTGGAATGGAGGGATTGGGAACAGACTTTAACGTAATCTGTCCATGGGAGGCGTACAGTCACCTGGAGTTACATGAGCTGGCTCAATACGGCATTATATGATATATTTTCCTGTTATCCTGGATCCACCAGCAACATCCTGCACCTTAATATGTACATTTACAATCTCTTTAGCAAATGTTTGGTTAGTCACAGATAGACAGCATTTGTAACTAACTCAAATTAGTTAATCTACCTCTTCAAATTGAAGTTTCATGTAGTACTACACTTTCAAAAAAATTTATCATTTTACGGgatatttctggcagctggggtgccggataaaaaacttaaaattacgACCATTAAATCactgaaatatactgtaaaataacgataataaattacaaaaatttactagaaattacattttaaggaaatttctgttatttaacggctgttattttttCGTATTTTTTCAGCCACCCCATCTGCcagaaaaaacatgtaaaattacggatttttttttacatggtagaTTTCACTCTTTCGCCAATGATAATCTCAGACACTTTTTCTTATTCCTCATTTTTTACTTCATCATCTTACCTAATAATAGTATTgtcttattattatataatgggCATTATAGCTGCAACATCAAGCTTTAGTTTCCATATAAATATATGGAATGTAGCTGGATCTTTTTAATGatggatgtttttgtttttattttgttgaactgGGACAGTTGTGTCATGTACAGTAtcagtgtgtgtacagtatgtgagtGTGCTGTGGGTCTCAGCGTCTGCCATAGCGCGAGTACTGGGAGCAGCTCTCTATGAGAAACCGGCCCAGTTTATTGGCCTTATGATGCTGGAGAATCATACTAAAATGAGCTCAACTCATTCCCAGCAGCACAGAATATTGTAGGTTTGGACGTCAATTAAAGCTtgattattttc

Function

symbol description
pde6ga Predicted to enable 3',5'-cyclic-GMP phosphodiesterase activity and cGMP binding activity. Predicted to be involved in positive regulation of G protein-coupled receptor signaling pathway and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to act upstream of or within visual perception. Predicted to be active in photoreceptor outer segment membrane. Is expressed in epiphysis; retinal photoreceptor layer; and retinal rod cell. Human ortholog(s) of this gene implicated in retinitis pigmentosa 57. Orthologous to human PDE6G (phosphodiesterase 6G) and PDE6H (phosphodiesterase 6H).

GO:

id name namespace
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway biological_process
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway biological_process
GO:0050896 response to stimulus biological_process
GO:0007601 visual perception biological_process
GO:0000187 activation of MAPK activity biological_process
GO:0042622 photoreceptor outer segment membrane cellular_component
GO:0016787 hydrolase activity molecular_function
GO:0030553 cGMP binding molecular_function
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity molecular_function
GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050522-144 Predicted to enable 3',5'-cyclic-GMP phosphodiesterase activity and cGMP binding activity. Predicted to be involved in positive regulation of G protein-coupled receptor signaling pathway and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to act upstream of or within visual perception. Predicted to be active in photoreceptor outer segment membrane. Is expressed in epiphysis; retinal photoreceptor layer; and retinal rod cell. Human ortholog(s) of this gene implicated in retinitis pigmentosa 57. Orthologous to human PDE6G (phosphodiesterase 6G) and PDE6H (phosphodiesterase 6H).

Ensembl:

ensembl_id ENSDARG00000056791

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00049858 True 1227 mRNA 0.38 4 19460991 19466015

Neighbor

gene id symbol gene type direction distance location
XLOC_025245 zgc:123297 coding upstream 3218 19446997 ~ 19457773 (+)
XLOC_025244 spc24 coding upstream 97010 19355869 ~ 19363981 (+)
XLOC_025242 kri1 coding upstream 105791 19336286 ~ 19355200 (+)
XLOC_025243 BX322663.1 coding upstream 111174 19349719 ~ 19349817 (+)
XLOC_025240 ldlra coding upstream 137302 19299309 ~ 19323689 (+)
XLOC_025247 CU571315.1 coding downstream 2762 19468777 ~ 19477473 (+)
XLOC_025248 NA coding downstream 6948 19472963 ~ 19473197 (+)
XLOC_025249 rprml coding downstream 143623 19609638 ~ 19610990 (+)
XLOC_025250 itgb3a coding downstream 155019 19621034 ~ 19649535 (+)
XLOC_025251 mettl2a coding downstream 199304 19665319 ~ 19682819 (+)
XLOC_025429 BX649540.1 misc downstream 10782724 30248739 ~ 30249036 (+)
XLOC_025241 BX322663.3 non-coding upstream 147884 19312991 ~ 19313107 (+)
XLOC_025235 CU151886.1 non-coding upstream 543408 18917461 ~ 18917583 (+)
XLOC_025234 CU151886.2 non-coding upstream 568225 18892650 ~ 18892766 (+)
XLOC_025233 AL772362.1 non-coding upstream 593039 18867835 ~ 18867952 (+)
XLOC_025257 NA non-coding downstream 593663 20059678 ~ 20064732 (+)
XLOC_025259 NA non-coding downstream 732287 20198302 ~ 20198619 (+)
XLOC_025261 NA non-coding downstream 1025187 20491202 ~ 20509513 (+)
XLOC_025262 BX248239.1 non-coding downstream 1213908 20679923 ~ 20680038 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01086655_00000996_00004036 NA coding CI01086655 null 374 ~ 4036 (-)