XLOC_036004 (tp73)


Basic Information

Item Value
gene id XLOC_036004
gene name tp73
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007119.7
NCBI id CM002892.2
chromosome length 54304671
location 48848200 ~ 48935476 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00070508
CCCCAACCCAACCCTCCACAGCCAAGAGCACTCACTCCGTGAGCCTATTTACCCTATACCTGCATAATCAGCCTCATCTCCCGCTCTCTCATAACCTATATAACctaaaacaaaaatagtaattcAGCGTGGTTATGATGTTCAACGGCTTAATCCGCAGTTCATGACAGGGCTGTAGTTTCCGCGGGTCAGCAGCAGGTCAAGGATTTTGGGATCCAGAAAACATCACCATAGTTTGGTCCAAGCCAGGAATATCACTTCTTTGTGTGATCTGCCCTGCGGTGGATTGTCCAACATCCAAGATGTCCCAGTCGTCCACCGCTGATGAGGGTCCAACCTTTGAGCACTTGTGGAGTACCCTTGAACCCGACAGCACGTATTTCGAGCTTCCTCAGGCGGGACACTCAGGGGACAGAGCTTCCAGCAGCCTGCCCGGCAACCGCGCTGAGGTCTGCATGGACGTCTACCACATGAGAGACATGAGGGACATGAACGACAACGTCATGTCTCAGTACAGCCTACTGAGCAGCAGTATGGACCAAGGTTTGGGGAACAGAGCAGCGTCTACCAGTCCCTACAGCTCAGAGACCACCTCCAACGTGCCAACGCCGTCGCCGTACTCGCAGCCAAACTCAACCTTCGAGGCCATGTCTCCAGCCCCGGCCATCCCTTCCAATACAGACTACCCCGGGCCGCACAACTTCGAGGTCACTTTCCAGCAGTCCAGCACCGCCAAGTCAGCCACCTGGACGTACTCTCCATTGCTCAAGAAATTATACTGTCAGATTGCAAAGACTTGTCCGATTCAGATCAAACTGGCATCTTCACCCCCGAACGGCAGTGTGATCCGAGCCATGCCCATCTACAAGAAGGCTGAGCACGTCACAGAGGTGGTCAAACGTTGCCCGAATCACGAACTCGGACGGGACTTCAACGAAAGTCAGACGGCTCCTGCCAGTCATTTGATAAGAGTAGAGGGCAATAATCTGTGTCAGTATGTGGACGACCCAGTAACAGGTCGACAGAGTGTTCTGGTCCCGTATGAGTCTCCACAGGTGGGCACAGAGTTCACGACCATTCTGTATAATTTCATGTGCAACAGCAGTTGTGTTGGAGGAATGAACCGCAGGCcaatcctcatcatcatcacgcTGGAGACACGAGACGGTCAGGTTCTCGGTAGGCGCTCATTTGAGGGACGGATTTGTGCTTGTCCGGGTCGCGACCGAAAAGCAGACGAAGACCATTTCAGGGAGCAACAGGCTCTAAACGAGAGCGTGGCCAAAAATGGAAATGCCAATAAACGAAATTTCAAACAGACTCCAACCAATATTACAGGCCCTTCCATCAACATCAAGAAGAGGAGGCACGGAGAAGAGGAGATGTATTACATACCAGTGCGCGGCCGGGAAAACTTTGACATCCTGATGAAGATAAAGGACAGTTTGGAGCTTGTAGAGTTTGTCCCACAACAGTTAGTGGATTCATAcagacaacaacaacagcagctcCTCCAGAGACAAAATCATGTCGCCTCTCCGTCTTCATACGGGACACTCAATAACATGAATAAGATTCACGGGCCAATAAGCAAACTGCCCTCAGTGAATCAGCTCGTGACACAACAGACCCAGCAGAGCGCAGGACCCTCCGCATCTTTATCACATATGGGTGCGAACATGTTGGGAGGACACCACATGCAGTCTAACGGCGATGTGAATGGCGCTCACCAGTCCCAGTCTATAGTGTCCACCTCTCACTGTACCCCTCCCCCACCTTACAACCCCGACCCCAGCCTCGTCAGTTTCTTAACCAGCCTGGGCTGCCAAAACTGTATCGACTACTTCACGTCTCAGGGACTCCAGAGTGTGTACCACCTTCAGACTCTTACTATGGAGGACCTTGGGGCCCTGAAGATTCCTGAGCAGTTCCGGCTGGCGATCTGGAGGGGTCTGCAGGAGATGAAGCAGGGCCATGATTATGGCCAGCAGCTGATCCGCTCCAGCAGTAACATGGCCACCATGGCCATCGGCCCCAGCGGAGAACTGCAACGGCAGCGCGTCATGGAGGCCGTGCACTTCAGAGTCCGCCATACCATCACCATCCCCAACCGCGGACCGGCCAACGGACCCGAGGAATGGCCCGACTTCGGCTTTGACATGCCCGACTGCAGGTTACACAAACACTCCATTAAAGAGGAGTTTGCCGAAGGCGACGTTCACTGAGAAGAGCCGGCTTTTTTCCCCACACGCATTACTATATTGTACGTATTGGGTCATTGAAACTGCAGCAGACGGTTTATATTTTCAATATAGTAGCACTTCTGTACTTTTTAGTTCcagacaaaacattttatttgattgtcATTCGTGGCCTTACGCTAATATTACAATcactaacaacaacaaaacagtcaATTTAAAGTCACTGATTAAAAACAACGATATTGGTGGTATGTAGATTTTTGAATGGGTAGAAGCCGTGTGACATTTCAGAATATTGCCTTATTTATTATTTGGCTTGgtgtaaataatatttgtgcaATTGTGTATGATATTGACGCATGTATGTTCGAAACAAGTGTGAAGTTGTGGATTAAGTAAATGCTTTGACTTATGAA
>TCONS_00070509
ATTGTCCAACATCCAAGATGTCCCAGTCGTCCACCGCTGATGAGGGTCCAACCTTTGAGCACTTGTGGAGTACCCTTGAACCCGACAGCACGTATTTCGAGCTTCCTCAGGCGGGACACTCAGGGGACAGAGCTTCCAGCAGCCTGCCCGGCAACCGCGCTGAGGTCTGCATGGACGTCTACCACATGAGAGACATGAGGGACATGAACGACAACGTCATGTCTCAGTACAGCCTACTGAGCAGCAGTATGGACCAAGGTTTGGGGAACAGAGCAGCGTCTACCAGTCCCTACAGCTCAGAGACCACCTCCAACGTGCCAACGCCGTCGCCGTACTCGCAGCCAAACTCAACCTTCGAGGCCATGTCTCCAGCCCCGGCCATCCCTTCCAATACAGACTACCCCGGGCCGCACAACTTCGAGGTCACTTTCCAGCAGTCCAGCACCGCCAAGTCAGCCACCTGGACGTACTCTCCATTGCTCAAGAAATTATACTGTCAGATTGCAAAGACTTGTCCGATTCAGATCAAACTGGCATCTTCACCCCCGAACGGCAGTGTGATCCGAGCCATGCCCATCTACAAGAAGGCTGAGCACGTCACAGAGGTGGTCAAACGTTGCCCGAATCACGAACTCGGACGGGACTTCAACGAAAGTCAGACGGCTCCTGCCAGTCATTTGATAAGAGTAGAGGGCAATAATCTGTGTCAGTATGTGGACGACCCAGTAACAGGTCGACAGAGTGTTCTGGTCCCGTATGAGTCTCCACAGGTGGGCACAGAGTTCACGACCATTCTGTATAATTTCATGTGCAACAGCAGTTGTGTTGGAGGAATGAACCGCAGGCcaatcctcatcatcatcacgcTGGAGACACGAGACGGTCAGGTTCTCGGTAGGCGCTCATTTGAGGGACGGATTTGTGCTTGTCCGGGTCGCGACCGAAAAGCAGACGAAGACCATTTCAGGGAGCAACAGGCTCTAAACGAGAGCGTGGCCAAAAATGGAAATGCCAATAAACGAAATTTCAAACAGACTCCAACCAATATTACAGGCCCTTCCATCAACATCAAGAAGAGGAGGCACGGAGAAGAGGAGATGTATTACATACCAGTGCGCGGCCGGGAAAACTTTGACATCCTGATGAAGATAAAGGACAGTTTGGAGCTTGTAGAGTTTGTCCCACAACAGTTAGTGGATTCATAcagacaacaacaacagcagctcCTCCAGAGACAAAATCATGTCGCCTCTCCGTCTTCATACGGGACACTCAATAACATGAATAAGATTCACGGGCCAATAAGCAAACTGCCCTCAGTGAATCAGCTCGTGACACAACAGACCCAGCAGAGCGCAGGACCCTCCGCATCTTTATCACATATGGGTGCGAACATGTTGGGAGGACACCACATGCAGTCTAACGGCGATGTGAATGGCGCTCACCAGTCCCAGTCTATAGTGTCCACCTCTCACTGTACCCCTCCCCCACCTTACAACCCCGACCCCAGCCTCGTCAGTTTCTTAACCAGCCTGGGCTGCCAAAACTGTATCGACTACTTCACGTCTCAGGGACTCCAGAGTGTGTACCACCTTCAGACTCTTACTATGGAGGACCTTGGGGCCCTGAAGATTCCTGAGCAGTTCCGGCTGGCGATCTGGAGGGGTCTGCAGGAGATGAAGCAGGGCCATGATTATGGCCAGCAGCTGATCCGCTCCAGCAGTAACATGGCCACCATGGCCATCGGCCCCAGCGGAGAACTGCAACGGCAGCGCGTCATGGAGGCCGTGCACTTCAGAGTCCGCCATACCATCACCATCCCCAACCGCGGACCGGCCAACGGACCCGAGGAATGGCCCGACTTCGGCTTTGACATGCCCGACTGCAGGTTACACAAACACTCCATTAAAGAGGAGTTTGCCGAAGGCGACGTTCACTGAGAAGAGCCGGCTTTTTTCCCCACACGCATTACTATATTGTACGTATTGGGTCATTGAAACTGCAGCAGACGGTTTATATTTTCAATATAGTAGCACTTCTGTACTTTTTAGTTCcagacaaaacattttatttgattgtcATTCGTGGCCTTACGCTAATATTACAATcactaacaacaacaaaacagtcaATTTAAAGTCACTGATTAAAAACAACGATATTGGTGGTATGTAGATTTTTGAATGGGTAGAAGCCGTGTGACATTTCAGAATATTGCCTTATTTATTATTTGGCTTGgtgtaaataatatttgtgcaATTGTGTATGATATTGACGCATGTATGTTCGAAACAAGTGTGAAGTTGTGGATTAAGTAAATGCTTTGACTTATG
>TCONS_00070510
ATGTCCCAGTCGTCCACCGCTGATGAGGGTCCAACCTTTGAGCACTTGTGGAGTACCCTTGAACCCGACAGCACGTATTTCGAGCTTCCTCAGGCGGGACACTCAGGGGACAGAGCTTCCAGCAGCCTGCCCGGCAACCGCGCTGAGGTCTGCATGGACGTCTACCACATGAGAGACATGAGGGACATGAACGACAACGTCATGTCTCAGTACAGCCTACTGAGCAGCAGTATGGACCAAGGTTTGGGGAACAGAGCAGCGTCTACCAGTCCCTACAGCTCAGAGACCACCTCCAACGTGCCAACGCCGTCGCCGTACTCGCAGCCAAACTCAACCTTCGAGGCCATGTCTCCAGCCCCGGCCATCCCTTCCAATACAGACTACCCCGGGCCGCACAACTTCGAGGTCACTTTCCAGCAGTCCAGCACCGCCAAGTCAGCCACCTGGACGTACTCTCCATTGCTCAAGAAATTATACTGTCAGATTGCAAAGACTTGTCCGATTCAGATCAAACTGGCATCTTCACCCCCGAACGGCAGTGTGATCCGAGCCATGCCCATCTACAAGAAGGCTGAGCACGTCACAGAGGTGGTCAAACGTTGCCCGAATCACGAACTCGGACGGGACTTCAACGAAAGTCAGACGGCTCCTGCCAGTCATTTGATAAGAGTAGAGGGCAATAATCTGTGTCAGTATGTGGACGACCCAGTAACAGGTCGACAGAGTGTTCTGGTCCCGTATGAGTCTCCACAGGTGGGCACAGAGTTCACGACCATTCTGTATAATTTCATGTGCAACAGCAGTTGTGTTGGAGGAATGAACCGCAGGCcaatcctcatcatcatcacgcTGGAGACACGAGACGGTCAGGTTCTCGGTAGGCGCTCATTTGAGGGACGGATTTGTGCTTGTCCGGGTCGCGACCGAAAAGCAGACGAAGACCATTTCAGGGAGCAACAGGCTCTAAACGAGAGCGTGGCCAAAAATGGAAATGCCAATAAACGAAATTTCAAACAGACTCCAACCAATATTACAGGCCCTTCCATCAACATCAAGAAGAGGAGGCACGGAGAAGAGGAGATGTATTACATACCAGTGCGCGGCCGGGAAAACTTTGACATCCTGATGAAGATAAAGGACAGTTTGGAGCTTGTAGAGTTTGTCCCACAACAGTTAGTGGATTCATAcagacaacaacaacagcagctcCTCCAGAGACAAAATCATGTCGCCTCTCCGTCTTCATACGGGACACTCAATAACATGAATAAGATTCACGGGCCAATAAGCAAACTGCCCTCAGTGAATCAGCTCGTGACACAACAGACCCAGCAGAGCGCAGGACCCTCCGCATCTTTATCACATATGGGTGCGAACATGTTGGGAGGACACCACATGCAGTCTAACGGCGATGTGAATGGCGCTCACCAGTCCCAGTCTATAGTGTCCACCTCTCACTGTACCCCTCCCCCACCTTACAACCCCGACCCCAGCCTCGTCAGGACGCAGCCGCTTGGTCTTAGTGGGATTCCTTTTCTCTCTGAACAGTTTCTTAACCAGCCTGGGCTGCCAAAACTGTATCGACTACTTCACGTCTCAGGGACTCCAGAGTGTGTACCACCTTCAGACTCTTACTATGGAGGACCTTGGGGCCCTGAAGATTCCTGAGCAGTTCCGGCTGGCGATCTGGAGGGGTCTGCAGGAGATGAAGCAGGGCCATGATTATGGCCAGCAGCTGATCCGCTCCAGCAGTAACATGGCCACCATGGCCATCGGCCCCAGCGGAGAACTGCAACGGCAGCGCGTCATGGAGGCCGTGCACTTCAGAGTCCGCCATACCATCACCATCCCCAACCGCGGACCGGCCAACGGACCCGAGGAATGGCCCGACTTCGGCTTTGACATGCCCGACTGCAGGTTACACAAACACTCCATTAAAGAGGAGTTTGCCGAAGGCGACGTTCACTGA

Function

symbol description
tp73 Enables DNA-binding transcription factor activity. Acts upstream of or within embryonic cranial skeleton morphogenesis and regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including gonad; musculature system; nervous system; pharynx; and renal system. Human ortholog(s) of this gene implicated in breast cancer; lung cancer; nephroblastoma; and renal cell carcinoma. Orthologous to human TP73 (tumor protein p73).

GO:

id name namespace
GO:0006915 apoptotic process biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0051262 protein tetramerization biological_process
GO:0007049 cell cycle biological_process
GO:0007050 cell cycle arrest biological_process
GO:0048701 embryonic cranial skeleton morphogenesis biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
ko04390 Hippo signaling pathway
ko04115 p53 signaling pathway
ko04722 Neurotrophin signaling pathway
ko05162 Measles
ko03000 Transcription factors

ZFIN:

id description
ZDB-GENE-030814-2 Enables DNA-binding transcription factor activity. Acts upstream of or within embryonic cranial skeleton morphogenesis and regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including gonad; musculature system; nervous system; pharynx; and renal system. Human ortholog(s) of this gene implicated in breast cancer; lung cancer; nephroblastoma; and renal cell carcinoma. Orthologous to human TP73 (tumor protein p73).

Ensembl:

ensembl_id ENSDARG00000017953

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00070508 False 2620 mRNA 0.50 14 48848200 48935476
TCONS_00070509 False 2333 mRNA 0.50 13 48858132 48935474
TCONS_00070510 True 1969 mRNA 0.54 13 48858149 48935081

Neighbor

gene id symbol gene type direction distance location
XLOC_036003 tprg1l coding upstream 38464 48801402 ~ 48809736 (+)
XLOC_036002 NA coding upstream 95924 48750253 ~ 48752276 (+)
XLOC_036001 NA coding upstream 101557 48731449 ~ 48746643 (+)
XLOC_036000 BX323876.1 coding upstream 154946 48691469 ~ 48693254 (+)
XLOC_035999 nppa coding upstream 230536 48613040 ~ 48617664 (+)
XLOC_036006 rer1 coding downstream 6994 48942470 ~ 48961405 (+)
XLOC_036007 aak1a coding downstream 30291 48965767 ~ 49044259 (+)
XLOC_036008 NA coding downstream 125525 49061001 ~ 49063846 (+)
XLOC_036009 ddx51 coding downstream 129872 49065348 ~ 49089382 (+)
XLOC_036010 zgc:56525 coding downstream 156563 49092039 ~ 49115695 (+)
XLOC_035995 BX649478.1 non-coding upstream 320654 48514551 ~ 48527546 (+)
XLOC_035993 CABZ01070222.1 non-coding upstream 457522 48390562 ~ 48390678 (+)
XLOC_036013 NA non-coding downstream 265836 49201312 ~ 49207469 (+)
XLOC_036014 NA non-coding downstream 286638 49222114 ~ 49231343 (+)
XLOC_036015 NA non-coding downstream 373160 49308636 ~ 49310816 (+)
XLOC_036016 BX537103.1 non-coding downstream 443414 49378890 ~ 49380303 (+)

Expression


Co-expression Network