XLOC_036769 (nkx2.7)


Basic Information

Item Value
gene id XLOC_036769
gene name nkx2.7
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007119.7
NCBI id CM002892.2
chromosome length 54304671
location 50284859 ~ 50287949 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00071794
GTCTAATAGCAGCGGAAAGAGCAAGATACGAGGCGACTTATGCAAGGAGATAGCCCACGACAGACTCTAAGGAAGAAGATTCTGCTTAATTGTGTAGGCCTGCAGTAACTTTTCAAAGTCACCTGATGCTGCTTTGAACTTGACAAGGTGAAACGGAGAACATTTCTTCCACGTTTCTTCAAGCACGCGCACGATGCTTCCGAGTCCTGTGACCTCCACTCCGTTTTCGGTAAAGGACATCCTGAAACTGGAGCAGCAGCAAGCGCTAAACCCTGGGGTATTCATGGGTGTTGAGCAGGACTCTGTGCCGCTGCAGTCGCTTCAGCTTCAGTGTATGCAGAACACCCTGAGTCGGAGTCTGGATCTCCTTTACAGCCCGGAGAAAGGGATCCCCGGAGAACAGGTGAAATGCGACGACTTTGACATCGTCAGAAGCTCATGCGGATCTCCAACGGAAGAGGAGATGGATGCAAACGAAGAAACAAGCATGTGTCCATTTACCGACTCCAGTTACAGCAGTAAAAACGGCGAGACACTCCGGGAGAAACCGAAGCAGAGGCTGCGCAGGAAACCGCGGGTGCTTTTCTCCCAAACTCAAGTGTTTGAGCTGGAAAGACGCTTTAAGCAGCAGAGATACCTTTCGGCCCCGGAGCGTGACCACCTGGCTCTTGCACTGAAGCTCACATCCACACAGGTCAAAATTTGGTTCCAGAACCGGAGGTACAAGTGTAAGAGACAGCGGCAGGATAAATCCCTGGAGCTGGCCGGCCCGCGGAGGGTGGCGGTGCCTGTGCTGGTGCGCGATGGCAAACCCTGTCACGGAGCTCCGTACAATGTCACAGTATCATATCCCTACAATAACTATTACAACAGCTATGGAAATAACCCATACCACTGTAACTTCACTTCTGTGCCATCATTTGCCAACACGAGTCAAATACCCAATCACTTTGTGGACATGAATCTGACAACGGGAAGCGTTGATAGCATCAGAACTTGGTGAGACATCAGAGAAGAACTTGGATTAAAGACTCTTTTATCAAATGGCACTGGACTGGAGGATTTAAGAAACACTGTCATTTGCTTTAGATTGTTgactaattttatataaatatatatttgtttttatatttgtggtttacaaaacaacaccaaataaagaattaatatttaata

Function

symbol description
nkx2.7 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within heart development and regulation of cardiac chamber formation. Predicted to be active in nucleus. Is expressed in heart primordium and lateral plate mesoderm. Orthologous to human NKX2-6 (NK2 homeobox 6).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0030154 cell differentiation biological_process
GO:0055007 cardiac muscle cell differentiation biological_process
GO:0035050 embryonic heart tube development biological_process
GO:0003007 heart morphogenesis biological_process
GO:0060038 cardiac muscle cell proliferation biological_process
GO:0001947 heart looping biological_process
GO:1901210 regulation of cardiac chamber formation biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990415-179 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within heart development and regulation of cardiac chamber formation. Predicted to be active in nucleus. Is expressed in heart primordium and lateral plate mesoderm. Orthologous to human NKX2-6 (NK2 homeobox 6).

Ensembl:

ensembl_id ENSDARG00000021232

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00071794 True 1176 mRNA 0.47 2 50284859 50287949

Neighbor

gene id symbol gene type direction distance location
XLOC_036768 nkx3-1 coding downstream 25411 50256930 ~ 50259448 (-)
XLOC_036767 hp coding downstream 136911 50143194 ~ 50147948 (-)
XLOC_036766 NA coding downstream 144876 50137475 ~ 50139983 (-)
XLOC_036765 si:ch73-132k15.2 coding downstream 149315 50134007 ~ 50135544 (-)
XLOC_036764 antxr1a coding downstream 151795 50066802 ~ 50133064 (-)
XLOC_036770 stc1 coding upstream 34820 50322769 ~ 50346246 (-)
XLOC_036771 ido1 coding upstream 175278 50463227 ~ 50482781 (-)
XLOC_036772 NA coding upstream 220812 50508761 ~ 50511887 (-)
XLOC_036773 CABZ01060030.1 coding upstream 229833 50517782 ~ 50517903 (-)
XLOC_036774 CABZ01060030.2 coding upstream 232190 50520139 ~ 50525360 (-)
XLOC_036762 NA non-coding downstream 413277 49864078 ~ 49871582 (-)
XLOC_036761 NA non-coding downstream 458942 49803988 ~ 49825917 (-)
XLOC_036746 CT737131.1 non-coding downstream 1132384 49149904 ~ 49152475 (-)
XLOC_036745 NA non-coding downstream 1219820 49043744 ~ 49065039 (-)
XLOC_036776 FO704819.1 non-coding upstream 601640 50889589 ~ 50898357 (-)
XLOC_036777 NA non-coding upstream 665709 50953658 ~ 50954244 (-)
XLOC_036779 CR855300.2 non-coding upstream 739890 51027839 ~ 51027953 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000050_03721951_03724091 NKX2.7 coding CI01000050 null 3721797 ~ 3724452 (-)