XLOC_037661 (hnmt)


Basic Information

Item Value
gene id XLOC_037661
gene name hnmt
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 10138196 ~ 10145880 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00073951
ATCATCACAGGCAGTGTGTGTTAACGGAGAAGAGGTCATCTATTTCAGCCAGTGGAAACCATGGCAGCTCCATTCAAAACACTTGTGGAAGATTATCCCAGATACCTCAAATCATTCGAGCTCTTTCTTGAGCGCTCATCAGAGCACCAGTGCATGCAGGACTTCATTCATAATACGCTCCCCGACATTCTGGCAAGCATTGGTGGAGGGAGATCTGTTTTCAATGTAATGGGAGTGGGGAGCGGAGCAGGTGATATTGATCTAGAGATGCTAGCACAGCTGCACCTGAAACATCCACATGTCAAAGTCGACAATGAAGTGGTGGAACCAAGTAATGACATGCTCTACAAGTATAAAGCGAGAGTGTCAACATCTCCCGATCTTGCTTATATCAACTTTACATGGAATAAGATGACAGCATCTGAATTTGAAAAACAATGGCAAGAAAAAACACCTGAGAAAAAGATGGACTTCATTCACATGATACAGATGCTGTACTATGTCAAAGATCCAAATGCCACTGTTTCATTTTTTCGAAGTCTGCTTGAAAAAGATGGGAAACTCTTAATTATTCTGGTGTCAGgtgAGAGCGGGTGGGGCAAATTATGGACCACATTTCGAAAGCAGCTCTGTTACACTGAGATGAGCCAGTGTGTCACTACAGGAGAAATAAAGAGCTTTTTAGATTCTGAGGGCATCCCGTACCATAAATATTTGCTTCTGTCCCAGATGGACATCACAGAATGCTTCACTGAAGGAGACCAGGAGGGAGAACTGCTTTTAGATTTCCTAACAGAGGTGAAAGAGTTCAGTAAAAATGCTCCTGAACGTTTGAAGAAAGAAGTGCTTGACGTACTGAGACATCCTGACTGCAGTAAAGAGGTGGACGGCAGGATCATATTCAATAACAACCTTGAAGTCTTAGTCATTGAGCCATagaataaaatctgta
>TCONS_00073952
TTCGTCTTTAAGGGTGTAGGCGGAGACTCTGTGATGGGCGTGGCtacatttctgtcttcatgtcaTGTGCGGCGGCCCACACATCATCATCACAGGCAGTGTGTGTTAACGGAGAAGAGCACAGGTCATCTATTTCAGCCAGTGGAAACCATGGCAGCTCCATTCAAAACACTTGTGGAAGATTATCCCAGATACCTCAAATCATTCGAGCTCTTTCTTGAGCGCTCATCAGAGCACCAGTGCATGCAGGACTTCATTCATAATACGCTCCCCGACATTCTGGCAAGCATTGGTGGAGGGAGATCTGTTTTCAATGTAATGGGAGTGGGGAGCGGAGCAGGTGATATTGATCTAGAGATGCTAGCACAGCTGCACCTGAAACATCCACATGTCAAAGTCGACAATGAAGTGGTGGAACCAAGTAATGACATGCTCTACAAGTATAAAGCGAGAGTGTCAACATCTCCCGATCTTGCTTATATCAACTTTACATGGAATAAGATGACAGCATCTGAATTTGAAAAACAATGGCAAGAAAAAACACCTGAGAAAAAGATGGACTTCATTCACATGATACAGATGCTGTACTATGTCAAAGATCCAAATGCCACTGTTTCATTTTTTCGAAGTCTGCTTGAAAAAGATGGGAAACTCTTAATTATTCTGGTGTCAGgtgAGAGCGGGTGGGGCAAATTATGGACCACATTTCGAAAGCAGCTCTGTTACACTGAGATGAGCCAGTGTGTCACTACAGGAGAAATAAAGAGCTTTTTAGATTCTGAGGGCATCCCGTACCATAAATATTTGCTTCTGTCCCAGATGGACATCACAGAATGCTTCACTGAAGGAGACCAGGAGGGAGAACTGCTTTTAGATTTCCTAACAGAGGTGAAAGAGTTCAGTAAAAATGCTCCTGAACGTTTGAAGAAAGAAGTGCTTGACGTACTGAGACATCCTGACTGCAGTAAAGAGGTGGACGGCAGGATCATATTCAATAACAACCTTGAAGTCTTAGTCATTGAGCCATagaataaaatc

Function

symbol description
hnmt Predicted to enable histamine N-methyltransferase activity. Predicted to be involved in histamine catabolic process and methylation. Predicted to be located in cytoplasm. Is expressed in adaxial cell and muscle pioneer. Human ortholog(s) of this gene implicated in Parkinson's disease; asthma; atopic dermatitis; autosomal recessive non-syndromic intellectual disability; and essential tremor. Orthologous to human HNMT (histamine N-methyltransferase).

GO:

id name namespace
GO:0032259 methylation biological_process
GO:0001695 histamine catabolic process biological_process
GO:0005737 cytoplasm cellular_component
GO:0046539 histamine N-methyltransferase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0008168 methyltransferase activity molecular_function
GO:0008170 N-methyltransferase activity molecular_function

KEGG:

id description
ko00340 Histidine metabolism
ko04147 Exosome

ZFIN:

id description
ZDB-GENE-040801-157 Predicted to enable histamine N-methyltransferase activity. Predicted to be involved in histamine catabolic process and methylation. Predicted to be located in cytoplasm. Is expressed in adaxial cell and muscle pioneer. Human ortholog(s) of this gene implicated in Parkinson's disease; asthma; atopic dermatitis; autosomal recessive non-syndromic intellectual disability; and essential tremor. Orthologous to human HNMT (histamine N-methyltransferase).

Ensembl:

ensembl_id ENSDARG00000012796

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00073951 False 952 mRNA 0.43 7 10138196 10145795
TCONS_00073952 True 1038 mRNA 0.44 7 10138200 10145880

Neighbor

gene id symbol gene type direction distance location
XLOC_037660 spopla coding downstream 70091 10050890 ~ 10068105 (-)
XLOC_037659 ugt1a1 coding downstream 134414 9969987 ~ 10003782 (-)
XLOC_037658 prmt2 coding downstream 177256 9953063 ~ 9960940 (-)
XLOC_037657 fstl1b coding downstream 296047 9735493 ~ 9842149 (-)
XLOC_037656 lrrc58b coding downstream 405984 9719225 ~ 9732212 (-)
XLOC_037662 thsd7ba coding upstream 6940 10152820 ~ 10532591 (-)
XLOC_037663 NA coding upstream 222500 10368380 ~ 10370625 (-)
XLOC_037664 tmbim1b coding upstream 612459 10758339 ~ 10769097 (-)
XLOC_037665 CABZ01053619.1 coding upstream 632347 10778227 ~ 10778615 (-)
XLOC_037666 si:ch1073-416j23.1 coding upstream 635807 10781687 ~ 10805231 (-)
XLOC_037651 AL954142.4 non-coding downstream 767330 9355372 ~ 9370866 (-)
XLOC_037649 NA non-coding downstream 849126 9286419 ~ 9289070 (-)
XLOC_037645 NA non-coding downstream 1087681 9026383 ~ 9050515 (-)
XLOC_037644 BX537313.1 non-coding downstream 1113927 9009123 ~ 9024269 (-)
XLOC_037638 NA non-coding downstream 1851988 8284155 ~ 8286208 (-)
XLOC_037667 BX000444.1 non-coding upstream 700038 10845918 ~ 10846549 (-)
XLOC_037671 NA non-coding upstream 1425432 11571312 ~ 11572354 (-)
XLOC_037673 NA non-coding upstream 1450107 11595987 ~ 11655031 (-)
XLOC_037675 NA non-coding upstream 1676499 11822379 ~ 11855305 (-)

Expression


Co-expression Network