XLOC_004518 (tfam)


Basic Information

Item Value
gene id XLOC_004518
gene name tfam
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 7254112 ~ 7263958 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009010
ATAAGGCACTGCGGTCGGACGGCAGATGGAATGGCGCCtttacaggaggaggagcagtGACAATCATAACAGTTGATTTCAAGATAGCTCGTTTTGTTCTGTTTTCATCGCGCATATATAATATTTCATAAGTATTATTGGTGAGATCGCAGCGCGTGCACGATGGCTCCATTCAGCTTGATGTCAGTGGGGGCTAATCTGCTGGTCAAGTCATTCAGCCTGTTCTCGAGTGCATCTGTTGTGAGGTGTTCATGTGTAGCTCCAGCGATAAAGAGTTTTAGCACTGCAACTCGAGGTCCACCCAAGAGACCCCTGACAGCATACATGACATTTGTAAAGGATATGCAGCCCACCGTCAGCAAACAAAATCCTGGCATAAAAAGTGTGGATGTTATGCGAAAGATTGCCCAGCAGTGGAAAATGTTGACCACCGAACAAAAGCAGCCATTTCAGGTTGCCTCTCTGGAGGCCAAGGAGCAATATAAACTTGCCTTGGAGAAATTCAAAGCCCAGCTCACCCCTGCAGAGAGTGCGGCTTTTGCGGAGGAAAAACGACAAAGAGTGGCCAAAAGAAAAGCCATTCGGAAAAAAAAGGAATTGAATAATCTTGGCAAGCCCAAACGCCCAAGGAGCACCTTCAACATCTTCATGGCGGAGCATTTTGTGGAGGCAAAGGGAACTACTACGCAGGCAAAATTGAAGTCACTAAGAGATGACTGGAATCGCTTGAGCGACACACAAAAACAAATGTACATACAGCTGGCAGAGGACGATAAAGTCCGTTACAAGAATGAAATCAAATCGTGGGAGGAGCACATGATGGAGATCGGAAGAGAAGATCTTTTGCGGAGAAAGACGAAGAGCGCCCTCAAAGCCAAAGCCAAAACCAAAACCATAGCCACTAAAAACAGGAAAAAGACATCCAAAGTGACAGTGATAAAGGCAAAAGCGCCCAAAAAGAAGAAAGATGCTAGTGGAAAAGCTGTGTATTTCTAGGACTCTGATCAACAGAGTGTGTTGTATAAAAACCACAACCGTCCTCAATACAGTCTGCGCTTTTCCGTTCTTAGAGCTGCATTTATATAGTGTTCATGAAGGTTTGAAAACTGTGAAGATGCCTTCTTCATCTTTTCAATAAATTCCTCTTTTTGCTGGTTTTTCTGAATCATGCAAGCGATATTTGACCTCACCATGACTGCTTTCATAGTATTATATTGTATAAAGTGATATAACATTTCTTAAATTGTACTTTACTGACACGCGTTTGCTTAGAATGAGTTTGCTTTAAAAGAGGACGCCATGTTGTTTGTATGTCTTTACTTACAAAATAAACATCCACTTTTTCTATAAAAGCAA

Function

symbol description
tfam Predicted to enable DNA binding activity, bending and transcription cis-regulatory region binding activity. Predicted to be involved in transcription initiation from mitochondrial promoter. Predicted to be located in nucleus. Is expressed in brain; muscle; pericardial region; pharyngeal arch 3-7; and somite. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Parkinson's disease; amyotrophic lateral sclerosis; and mitochondrial DNA depletion syndrome 15. Orthologous to human TFAM (transcription factor A, mitochondrial).

GO:

id name namespace
GO:0006338 chromatin remodeling biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0005634 nucleus cellular_component
GO:0008134 transcription factor binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003682 chromatin binding molecular_function
GO:0008301 DNA binding, bending molecular_function

KEGG:

id description
ko04371 Apelin signaling pathway
ko05016 Huntington disease
ko03029 Mitochondrial biogenesis

ZFIN:

id description
ZDB-GENE-061013-552 Predicted to enable DNA binding activity, bending and transcription cis-regulatory region binding activity. Predicted to be involved in transcription initiation from mitochondrial promoter. Predicted to be located in nucleus. Is expressed in brain; muscle; pericardial region; pharyngeal arch 3-7; and somite. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Parkinson's disease; amyotrophic lateral sclerosis; and mitochondrial DNA depletion syndrome 15. Orthologous to human TFAM (transcription factor A, mitochondrial).

Ensembl:

ensembl_id ENSDARG00000063145

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009010 True 1356 mRNA 0.43 7 7254112 7263958

Neighbor

gene id symbol gene type direction distance location
XLOC_004517 CU184911.1 coding upstream 545869 6708129 ~ 6708243 (+)
XLOC_004516 dkk1b coding upstream 786437 6465557 ~ 6467675 (+)
XLOC_004515 NA coding upstream 802503 6195170 ~ 6451609 (+)
XLOC_004514 NA coding upstream 1082184 6156963 ~ 6171928 (+)
XLOC_004513 NA coding upstream 1100991 6149007 ~ 6153121 (+)
XLOC_004519 bicc1b coding downstream 135445 7399403 ~ 7429824 (+)
XLOC_004520 FP102277.2 coding downstream 156074 7420032 ~ 7420148 (+)
XLOC_004521 phyhiplb coding downstream 181637 7445595 ~ 7513794 (+)
XLOC_004522 FQ311940.1 coding downstream 297107 7561065 ~ 7561202 (+)
XLOC_004523 CABZ01050061.1 coding downstream 468576 7732534 ~ 7732650 (+)
XLOC_004512 NA non-coding upstream 1101533 6144705 ~ 6152579 (+)
XLOC_004524 NA non-coding downstream 535843 7799801 ~ 7841013 (+)
XLOC_004527 NA non-coding downstream 779563 8043521 ~ 8046466 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000047_01824882_01828103 TFAM coding CI01000047 null 1824882 ~ 1828952 (-)