LOC113547453 (chrna1,LOC108266097)


Basic Information

Item Value
gene id LOC113547453
gene name chrna1,LOC108266097
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047599.1
NCBI id CM018545.1
chromosome length 32114633
location 17473115 ~ 17482009 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026947803.2
AGTAGCATAAAGCAGACCAGACAGCTCAGTGAGAAacgagaagagacagagagacaggcaccGGACTCGAATATTAAACCGCCCAGAccatacatgtttaaaaaaaagaggcttgTAAACTGGCGTTTTGTTATTCTTTCCTTTGAGAAGAGAGAGCaggtttttccatttttatatgAATACCAGTGACATGAAGTGGCTTCATTTGGTTTCTCTgctcctctctgtctctacaGGACTGGTGTGCTGTTCAGAGGATGAGACTCGTCTAGTGAAAAAACTCTTCTCCGGGTATAATAAAGTGGTCAGACCTGTCAATCACTTTAAAGATGCTGTGGTGGTCACTGTAGGACTGCAGCTAATCCAACTTATTAGTGTGGATGAGGTAAACCAAATTGTCACAACCAACGTACGTCTAAAACAGCAATGGAAAGATGTGAACCTGCAGTGGAACCCAGAGGAGTACGGAGGAATAAAAAAGATCCGAGTTCCCTGCACTGACATTTGGAGACCTGACCTTGTTCTCTATAACAATGCTGACGGTGACTTTGCCATTGTGCATGAGACCAAAGTTCTGCTAGAATATACAGGAATGATCACCTGGAACCCGCCCGCCATCTTTAAGAGCTACTGCGAGATCATTGTGCTTCACTTCCCCTTTGACTTACAGAACTGCAGCATGAAACTCGGAACATGGACATTTGATGGAAATCTTGTCGTCATCAACCCTGACAGCGATCGGCCAGACCTGAGTAACTTTATGGAGAGTGGTGAGTGGGTGATGAAGGACTACAGGAGCTGGAAGCACTGGGTTTATTACGCCTGTTGCCAAGACACTCCATACCTGGATATCACCTACCATTTCCTCTTGCTGAGACTGCCGCTCTACTTTATTGTCAACGTGATCATCCCATGcatccttttctctttcctgaCTGGCCTGGTCTTCTACCTGCCCACAGACTCAGgTGAGAAGATGACCCTCAGTATCTCTGTCCTGTTGTCTCTGACTGTGTTCTTGCTGGTGATCGTGGAGCTCATCCCTTCTACCTCAAGCGCTGTTCCTCTCATTGGGAAATACATGCTCTTCACCATGATCTTCGTCATTGCCTctatcatcatcactgtcattgtCATCAACACACACCACCGCTCACCTAGCACACACACCATGCCTGCCTGGGTTCGCAAGATTTTTATTGAAACCATCCCCAATTGGATGTTCTTCTCCGCTATGAAGAGGCCCAGCGTGGAAAAACGcactaaaaacattttcacccCTGATCTGGACATCTCTGATATCTCAGGGAAGCCGATGCCCACTGCTGTGCCCTTCCAATCACCCATAACCAAAAACCCAGATGTACGCAGTGCTATAGAAGGAGTCAAATACATCGCAGAAACCATGAAATCAGATGAGGAGTCCAACAATgccTGTGATGAGTGGAAGTTTGTTGCGATGGTTCTGGACCACATTTTGCTCTGTGTTTTCATGGCAGTGTGTATAATTGGAACACTGGCTGTCTTTGCTGGGAGACTCATTGAGCTCAGTCTTTTATAACATGGTTATGAtattatatcaataattataatataaggTGCCTTTGGAAGGATAATTATGTACATAAATTCATAATGTCTAGTATGATGTGCATCATTATATGAATGTTGGCCGAAAAACATGGAgtaatgattatatattatattgttttatcaGAAACTTGTGTCATACACATTCAAGTCACAGTATGCAAAGCAGTGCCTAAATGTAGGCTGATTTATATTCACTATTGATATAGATTTTTCTTAGAAAATGCAACTGCTTTGATATGAATAAAAGTATATCCTTTTGTCTAAAATGCA

Function

symbol description
chrna1 Enables cation channel activity. Contributes to acetylcholine binding activity and acetylcholine receptor activity. Acts upstream of or within several processes, including chemical synaptic transmission; chondrocyte intercalation involved in growth plate cartilage morphogenesis; and skeletal muscle fiber development. Part of acetylcholine-gated channel complex. Is expressed in adaxial cell; musculature system; and somite. Used to study congenital myasthenic syndrome. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 1A and congenital myasthenic syndrome 1B. Orthologous to human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit).

NR:

description
PREDICTED: acetylcholine receptor subunit alpha

GO:

id name namespace
GO:0048741 skeletal muscle fiber development biological_process
GO:0007271 synaptic transmission, cholinergic biological_process
GO:0007274 neuromuscular synaptic transmission biological_process
GO:0003428 chondrocyte intercalation involved in growth plate cartilage morphogenesis biological_process
GO:0030516 regulation of axon extension biological_process
GO:0043113 receptor clustering biological_process
GO:0086009 membrane repolarization biological_process
GO:0006812 cation transport biological_process
GO:0008045 motor neuron axon guidance biological_process
GO:0045211 postsynaptic membrane cellular_component
GO:0005892 acetylcholine-gated channel complex cellular_component
GO:0030054 cell junction cellular_component
GO:0042166 acetylcholine binding molecular_function
GO:0015464 acetylcholine receptor activity molecular_function

KEGG:

id description
K04803 CHRNA1; nicotinic acetylcholine receptor alpha-1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026947803.2 True 1863 mRNA 0.43 9 17473115 17482009

Neighbor

gene id symbol gene type direction distance location
wipf1a LOC108267026 coding downstream 824 17465688 ~ 17472291 (-)
gpr155a gpr155 coding downstream 8839 17449880 ~ 17464276 (-)
cir1 cir1 coding downstream 29593 17437158 ~ 17443522 (-)
ppp1r9ala LOC108266327 coding downstream 223283 17216721 ~ 17249832 (-)
dync1i2a dync1i2 coding downstream 263217 17176681 ~ 17209898 (-)
chn1 chn1,LOC107742958,LOC107739458,LOC106590032 coding upstream 4039 17486048 ~ 17523051 (-)
atf2 atf2,LOC107739459,LOC107671311,LOC107657392,LOC107742976 coding upstream 47928 17529937 ~ 17556165 (-)
atp5mc3a atp5g3,LOC108266717,LOC108424356,LOC103027531,LOC105908030 coding upstream 74810 17556819 ~ 17560073 (-)
lnpa lnpk coding upstream 185557 17667566 ~ 17679161 (-)
nfe2l2a nfe2l2,LOC107579917 coding upstream 399762 17881771 ~ 17896933 (-)
LOC117597450 NA non-coding downstream 41684 17407218 ~ 17431431 (-)
G84227 NA non-coding downstream 81168 17391684 ~ 17391947 (-)
G84189 LOC108266646 non-coding downstream 126765 17332492 ~ 17346350 (-)
G84182 NA non-coding downstream 148237 17324045 ~ 17324878 (-)
G84177 NA non-coding downstream 161160 17307569 ~ 17311955 (-)
G84394 NA non-coding upstream 244644 17726653 ~ 17727997 (-)
LOC117597384 NA non-coding upstream 258628 17740637 ~ 17744025 (-)
G84411 NA non-coding upstream 351366 17833375 ~ 17833589 (-)
G84881 NA non-coding upstream 649401 18131410 ~ 18131998 (-)
G84880 ino80d,LOC106582458 non-coding upstream 651393 18133402 ~ 18133689 (-)
sp3a sp3 other downstream 91943 17371979 ~ 17381172 (-)
mettl8 mettl8 other downstream 433272 17028237 ~ 17039843 (-)
si:dkey-91i10.2 LOC108266132,LOC106530433,LOC107658202 other downstream 1066637 16370227 ~ 16406478 (-)
G83554 NA other downstream 1252249 16219964 ~ 16220866 (-)
lmo7a lmo7 other downstream 1396495 16043283 ~ 16076620 (-)
evx2 evx2,LOC107657379,LOC107671304 other upstream 213281 17695290 ~ 17699980 (-)
LOC113526313 baz2b other upstream 1431378 18913387 ~ 18968492 (-)
grb14 grb14 other upstream 1961082 19443091 ~ 19494515 (-)
steap3 steap3,dbi,LOC107560815,LOC107747240 other upstream 2086740 19568749 ~ 19586103 (-)
G85848 NA other upstream 2744719 20226728 ~ 20237615 (-)

Expression


Co-expression Network