XLOC_005948 (nfkb2)


Basic Information

Item Value
gene id XLOC_005948
gene name nfkb2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 22717366 ~ 22735547 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00011760
TAACAGAGCGATCAATTTGTGAACGGATCCAGGCGAATACAGCGTTGATTACATGCTCTGGATTCACTGGATAAACGATGTTTTGTTTATGGTCTTCAAACCTGTGAAAATTTATTAACAGTGTTTAGTTGACTCGACGACTTGTAAAAACAACCCGACAACTAGTAAACAAGACGCAAGGAGCCCAGGTTCGGTTCGGATGATCCTGGAGAGCACAGAATGGCTGGAGCACTAAGGATGGATGATACACATTATCAAATTGGATTTGTGGTCAATGAGCCTATGACGTTTCCTTCAGCCTATGACGATCTTCCATATATGCCTGAAGCTTTTGAGGTGAAGCATGAGCCCTTTGTGCAAGAGACAGTTGATGGCCCTTACATACAGATAATTGAGGAGCCAAAGCAGAGAGGATTCAGATTTCGTTATGAATGTGAGGGCCCATCCCACGGTGGCCTACCAGGGGCCTCCAGTGAAAGGAACAGGAGGACGTATCCCACTGTCAagGTGTTAAACTTTGTGGGCAATGCTCGTGTGGAGGTTCAGCTGGTGACACACACAGACCCTCCACGAGTTCACGCACACAGCCTTGTGGGTCGACACTGTAATGAAAGCGGGGTCTGCAGTGTTGATGTCGGGCCTAGTGATTTCACAGCACAATTCAGTAACTTAGGCATCCTGCATGTCACAAAGAGAGGAGTGGTAGAAGTCTTAACGAAAAGGCTGAAAGAAGAGAAGAGGAAGGTGAAAGGGCCTGGATATAAGTTTAGTGATGCAGAGGAAAATGCTCTTATGCAAGAAGCCAAAGAGTTAGGCAAAAACATGGATCTGAACATTGTACGTTTAAAGTTCACTGCCTACCTGCAGGACAGCAATGGGAGTTACACCAGAGCATTGAAGCCTGTTGTGTCCAATCCTATATATGACAGCAAATCACCAAACGCTTCCAATCTGAAGATCTCTCGTATGGATAAAACCTCTGGGTCAGTGCTGGGAGGAGAAGAGGTCTTTCTGCTCTGTGATAAAGTTCAAAAAGATGATATTGACATCCGCTTTTATGAGGAGGAAGATGAATGGGAGGCATTAGGAGACTTTTCCCCCACTGATGTCcacaaacagtaTGCGATCGTGTTTAAGACGCCTCCGTACCGCTGCACCAACATCGATCGACCTGTCACAGTGTTTCTGCAGCTTAAGAGAAAGAAGGGCGGCGACTGTAGCGAACCAAAGCAGTTCACATATGTCCCACACAATCAAGACAAAGAAGAGGTTCAGAGGAAGAGGATGAAGGCTCTTCCAGATCATTATGGTGGCTGGCGTGGAGGACCCCAGGGTGGAGCAGGGGGGTTTGGAGGACCTGGATCTGgaacaggaggaggaggaggaatggGAGGAGGTTTCCCTTTTAATCCGATGGATAATTCAAGTTTTTTTGTTGGTGGATGTGGAGGATTTGGTGGGGGTGCACAAATGTCTGACTCCCCTCCTCAAACTGATGGAGCAAACACACAGTCTCAGTCGAACTCACAAATACGACAACAGCTCATTCAGATTGCTCTACACAATCGTGCTAATTTGGCGGCAAAATGCAATGCTCGTGCTTTATTACAGTACAGCAGCACAGGTGATGCGCGCCCCCTGCTGGCGCTGCAGAGACATCTGTGTGGAGTGCAAGATGAGAACGGAGACACGCCTCTTCACTTGGCCATTATTCACCAGAAAACTGTTGTGGCGGAACAGCTTATTAAGGCCTTGAACAGCAGCCCACAGCAGAAGTTCTTTAACAAACTCAACAAGCTCAGTCAGGCTCCTCTGCATCTGGCTGTGATCACCAAGCAACCCAAGTTAGTAGAGATGTTGATGAAATCGGGTGCAGACCCGAGTCTGCTGGACCGAGAGGGCCGGACAGTGCTTCACTTGGCCGCACATACTGGTGATGATGTCATACTAAGACTGGTCCTGAGCCTGCTAGGAGAGCATCACTCCCATTTAATAAACAGTGCTGACTTCACAGGTCAGTATCCAGTCCATCTCGCTGTGAAGAAAGATGGAGAGCGTTGTTTGCGATTGCTGGTAGAAGCAGGAGCAAAGATTAACATGCCAGAGCAGAAAAGTGGCTGCACTGCACTGCACCTGGCAGTGAGGGACAACCTGTTGAAACTGGCCTGTAATCTCATCACTGAGCTGAAGGCTGATGTGAATGCCTGTACCTACGGGGGCAACAGTCCTCTTCATTTAGCTGCCAGTCAGGGCTCTCCACATCTCTGCTCCATGCTGATCGCTGCAGGTGCTGATAAACGCATAGAGAATGACGAGCCTCTTTTCCTGAGCTCGTCTTCCTCAGATGAAGATGAAGAGAGCGAGAAGAAGCTTTCAGAAGACATGGTTCAGCAAGTTCACTGCTTGTCGATATCATCCGAGAGAGGAGTGTTTAACCCACGGAAGAGACCTGCTGCTGGACACACTCCCTTTGACCTGGCCAAATCCCAAAAGGTTAGAGATTTATTAGATGGCAGGAAAGGCCCCAAGCCCAATTCGCTCAGCCCTAAGAGGACCAAAATAAGCACAGAAGAAGTGAACCAGGATTTGGACAACGAGGTGCTGAGCAAGCTGTGTGGGATTCTAATTCATGACGATGTACCTTGGAGGGAACTGGCTGAAAAACTGGGTATGCTGACACTCACCCATCTGTACCAGGACAGCGCTTCACCCTGTCAGAAGCTTCTTGAAAGCTATCAGTTGAGTGGTGGTCCTGTGGATGGCCTGGTGGAGGCGCTGCAGGCTCTGGGTGTGAGGGAAGGAGTGAGGCTGCTGAGAGATAGTCAACCCAGAGAAGACAAACAGAGCTCAGACTCCACAGAGGACAGTGGCTTCGGCAGTCAGTCTATTGGAGAGGAGATGGCAAATCCTGCAGTGGGCAATCACTGATCATCAGTATCCATTCAATAAGGACAACTTAGCACTTTATTAGTTTACTGGTTCTTCAGGTGCAAACCGTTGGACTGTACATCATCTCAAATAGGAAATGCAGCACACCAGAGAAAGGATTAAAAAGAGCAGTTTTGAGGTCAAAATCTCTCAATGGTATTACATAACAATAAGACATGACAGGAATCGGTTGCTTTAAGATTCTCAAATCTCTGCGGTATGGAGTGAAGCTGCTTTTCTGCAGGCATTTCAGTGCTTGTATCTTATCCCCACATGAGCAACAAAACCCATCTGACTTCACGGTAATTTAACAATAATGCGACTGTCGTTTTTTAGCACAGCTGTAACCTTAACATGTTTGTAGAATGTACTGATATGAATAATTCTTGTCAGCTGTCGTTTGATATGATATGCAAACTTAAGAATATTTTCTGATACATCTAAAGACTTATGCtgtttatttatgtacatttttatgttGCAGTTGTGTGTTTCTTGGATGCAGAAATAAAtaagtttgttttattaaa
>TCONS_00011761
GAATCACAACCCCATCATACAGCGTGTAATCACTCATCAGATCCATCTTTTTCGGTCTGACAGGAGCCCAGGTTCGGTTCGGATGATCCTGGAGAGCACAGAATGGCTGGAGCACTAAGGATGGATGATACACATTATCAAATTGGATTTGTGGTCAATGAGCCTATGACGTTTCCTTCAGCCTATGACGATCTTCCATATATGCCTGAAGCTTTTGAGGTGAAGCATGAGCCCTTTGTGCAAGAGACAGTTGATGGCCCTTACATACAGATAATTGAGGAGCCAAAGCAGAGAGGATTCAGATTTCGTTATGAATGTGAGGGCCCATCCCACGGTGGCCTACCAGGGGCCTCCAGTGAAAGGAACAGGAGGACGTATCCCACTGTCAagGTGTTAAACTTTGTGGGCAATGCTCGTGTGGAGGTTCAGCTGGTGACACACACAGACCCTCCACGAGTTCACGCACACAGCCTTGTGGGTCGACACTGTAATGAAAGCGGGGTCTGCAGTGTTGATGTCGGGCCTAGTGATTTCACAGCACAATTCAGTAACTTAGGCATCCTGCATGTCACAAAGAGAGGAGTGGTAGAAGTCTTAACGAAAAGGCTGAAAGAAGAGAAGAGGAAGGTGAAAGGGCCTGGATATAAGTTTAGTGATGCAGAGGAAAATGCTCTTATGCAAGAAGCCAAAGAGTTAGGCAAAAACATGGATCTGAACATTGTACGTTTAAAGTTCACTGCCTACCTGCAGGACAGCAATGGGAGTTACACCAGAGCATTGAAGCCTGTTGTGTCCAATCCTATATATGACAGCAAATCACCAAACGCTTCCAATCTGAAGATCTCTCGTATGGATAAAACCTCTGGGTCAGTGCTGGGAGGAGAAGAGGTCTTTCTGCTCTGTGATAAAGTTCAAAAAGATGATATTGACATCCGCTTTTATGAGGAGGAAGATGAATGGGAGGCATTAGGAGACTTTTCCCCCACTGATGTCcacaaacagtaTGCGATCGTGTTTAAGACGCCTCCGTACCGCTGCACCAACATCGATCGACCTGTCACAGTGTTTCTGCAGCTTAAGAGAAAGAAGGGCGGCGACTGTAGCGAACCAAAGCAGTTCACATATGTCCCACACAATCAAGACAAAGAAGAGGTTCAGAGGAAGAGGATGAAGGCTCTTCCAGATCATTATGGTGGCTGGCGTGGAGGACCCCAGGGTGGAGCAGGGGGGTTTGGAGGACCTGGATCTGgaacaggaggaggaggaggaatggGAGGAGGTTTCCCTTTTAATCCGATGGATAATTCAAGTTTTTTTGTTGGTGGATGTGGAGGATTTGGTGGGGGTGCACAAATGTCTGACTCCCCTCCTCAAACTGATGGAGCAAACACACAGTCTCAGTCGAACTCACAAATACGACAACAGCTCATTCAGATTGCTCTACACAATCGTGCTAATTTGGCGGCAAAATGCAATGCTCGTGCTTTATTACAGTACAGCAGCACAGGTGATGCGCGCCCCCTGCTGGCGCTGCAGAGACATCTGTGTGGAGTGCAAGATGAGAACGGAGACACGCCTCTTCACTTGGCCATTATTCACCAGAAAACTGTTGTGGCGGAACAGCTTATTAAGGCCTTGAACAGCAGCCCACAGCAGAAGTTCTTTAACAAACTCAACAAGCTCAGTCAGGCTCCTCTGCATCTGGCTGTGATCACCAAGCAACCCAAGTTAGTAGAGATGTTGATGAAATCGGGTGCAGACCCGAGTCTGCTGGACCGAGAGGGCCGGACAGTGCTTCACTTGGCCGCACATACTGGTGATGATGTCATACTAAGACTGGTCCTGAGCCTGCTAGGAGAGCATCACTCCCATTTAATAAACAGTGCTGACTTCACAGGTCAGTATCCAGTCCATCTCGCTGTGAAGAAAGATGGAGAGCGTTGTTTGCGATTGCTGGTAGAAGCAGGAGCAAAGATTAACATGCCAGAGCAGAAAAGTGGCTGCACTGCACTGCACCTGGCAGTGAGGGACAACCTGTTGAAACTGGCCTGTAATCTCATCACTGAGCTGAAGGCTGATGTGAATGCCTGTACCTACGGGGGCAACAGTCCTCTTCATTTAGCTGCCAGTCAGGGCTCTCCACATCTCTGCTCCATGCTGATCGCTGCAGGTGCTGATAAACGCATAGAGAATGACGAGCCTCTTTTCCTGAGCTCGTCTTCCTCAGATGAAGATGAAGAGAGCGAGAAGAAGCTTTCAGAAGACATGGTTCAGCAAGTTCACTGCTTGTCGATATCATCCGAGAGAGGAGTGTTTAACCCACGGAAGAGACCTGCTGCTGGACACACTCCCTTTGACCTGGCCAAATCCCAAAAGGTTAGAGATTTATTAGATGGCAGGAAAGGCCCCAAGCCCAATTCGCTCAGCCCTAAGAGGACCAAAATAAGCACAGAAGAAGTGAACCAGGATTTGGACAACGAGGTGCTGAGCAAGCTGTGTGGGATTCTAATTCATGACGATGTACCTTGGAGGGAACTGGCTGAAAAACTGGGTATGCTGACACTCACCCATCTGTACCAGGACAGCGCTTCACCCTGTCAGAAGCTTCTTGAAAGCTATCAGTTGAGTGGTGGTCCTGTGGATGGCCTGGTGGAGGCGCTGCAGGCTCTGGGTGTGAGGGAAGGAGTGAGGCTGCTGAGAGATAGTCAACCCAGAGAAGACAAACAGAGCTCAGACTCCACAGAGGACAGTGGCTTCGGCAGTCAGTCTATTGGAGAGGAGATGGCAAATCCTGCAGTGGGCAATCACTGATCATCAGTATCCATTCAATAAGGACAACTTAGCACTTTATTAGTTTACTGGTTCTTCAGGTGCAAACCGTTGGACTGTACATCATCTCAAATAGGAAATGCAGCACACCAGAGAAAGGATTAAAAAGAGCAGTTTTGAGGTCAAAATCTCTCAATGGTATTACATAACAATAAGACATGACAGGAATCGGTTGCTTTAAGATTCTCAAATCTCTGCGGTATGGAGTGAAGCTGCTTTTCTGCAGGCATTTCAGTGCTTGTATCTTATCCCCACATGAGCAACAAAACCCATCTGACTTCACGGTAATTTAACAATAATGCGACTGTCGTTTTTTAGCACAGCTGTAACCTTAACATGTTTGTAGAATGTACTGATATGAATAATTCTTGTCAGCTGTCGTTTGATATGATATGCAAACTTAAGAATATTTTCTGATACATCTAAAGACTTATGCtgtttatttatgtacatttttatgttGCAGTTGTGTGTTTCTTGGATGCAGAAATAAAtaagtttgttttatt
>TCONS_00011762
AAGCGAGccagagagagggagggagacaTAATGCACATATCCGAGAAAGTGAAACAAACTCAGTTTTTTTGAGCCCTTTGTGTAAAACCGAGAGCTTCTGTCTCTACATTTGTTTGTCAGACAGGGATGGATGATACACATTATCAAATTGGATTTGTGGTCAATGAGCCTATGACGTTTCCTTCAGCCTATGACGATCTTCCATATATGCCTGAAGCTTTTGAGGTGAAGCATGAGCCCTTTGTGCAAGAGACAGTTGATGGCCCTTACATACAGATAATTGAGGAGCCAAAGCAGAGAGGATTCAGATTTCGTTATGAATGTGAGGGCCCATCCCACGGTGGCCTACCAGGGGCCTCCAGTGAAAGGAACAGGAGGACGTATCCCACTGTCAagGTGTTAAACTTTGTGGGCAATGCTCGTGTGGAGGTTCAGCTGGTGACACACACAGACCCTCCACGAGTTCACGCACACAGCCTTGTGGGTCGACACTGTAATGAAAGCGGGGTCTGCAGTGTTGATGTCGGGCCTAGTGATTTCACAGCACAATTCAGTAACTTAGGCATCCTGCATGTCACAAAGAGAGGAGTGGTAGAAGTCTTAACGAAAAGGCTGAAAGAAGAGAAGAGGAAGGTGAAAGGGCCTGGATATAAGTTTAGTGATGCAGAGGAAAATGCTCTTATGCAAGAAGCCAAAGAGTTAGGCAAAAACATGGATCTGAACATTGTACGTTTAAAGTTCACTGCCTACCTGCAGGACAGCAATGGGAGTTACACCAGAGCATTGAAGCCTGTTGTGTCCAATCCTATATATGACAGCAAATCACCAAACGCTTCCAATCTGAAGATC
>TCONS_00011763
TGAACCAGGATTTGGACAACGAGGTGCTGAGCAAGCTGTGTGGGATTCTAATTCATGACGATGTACCTTGGAGGGAACTGGCTGAAAAACTGGGTATGCTGACACTCACCCATCTGTACCAGGACAGCGCTTCACCCTGTCAGAAGCTTCTTGAAAGCTATCAGTTGAGTGGTGGTCCTGTGGATGGCCTGGTGGAGGCGCTGCAGGCTCTGGGTGTGAGGGAAGGAGTGAGGCTGCTGAGAGATAGTCAACCCAGAGAAGACAAACAGAGCTCAGGTACACACACAAATCAACACATGTAACAAACTAAACACTTTAACACTTCTAAATCAGACAGATCTCTGTGCACTCGAATATCGGAGCATATTGTTTCCTCAAGCCAAATCCATCTTATTGCTACCACCCTATaattgtgtacacacacacacacacacaattgtctTTAAGCCATACATTCATACAGAAACATCCTTAAGGCACAAAAGAAAActtgtgctggtttgtgcatcTTTTGTGGCTTTAATAAGAAGCAAATTAAGTTCAGTTCTTTCAGTGAAGAAGCATACAGCAGTTTGATTTGTATATTGTATTCTAttgcttttttcattattttgaggaCTTTGTTTTTACTTGGTTTTTACTTTGTACATTCTACCatggtattgaccttattcttcacgtacGAGTGAGCACAGCTATTGGAATTTTGTGGCTTGAGATTTGACTATAAGACTTTTCATGCACTTCTATTGATTTTTAGAGGTTAAAAAGAGCTCGATCTGCTGCttcatgttgcaaactgatattttcttatgaTATTCTTCTTCTTTCTATCTATAT

Function

symbol description
nfkb2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within angiogenesis and cholesterol homeostasis. Predicted to be located in cytoplasm and nucleus. Is expressed in male organism. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human NFKB2 (nuclear factor kappa B subunit 2).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0001525 angiogenesis biological_process
GO:0042632 cholesterol homeostasis biological_process
GO:0007165 signal transduction biological_process
GO:0005737 cytoplasm cellular_component
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
ko04010 MAPK signaling pathway
ko04064 NF-kappa B signaling pathway
ko04625 C-type lectin receptor signaling pathway
ko04380 Osteoclast differentiation
ko05200 Pathways in cancer
ko05203 Viral carcinogenesis
ko05224 Breast cancer
ko05166 Human T-cell leukemia virus 1 infection
ko05169 Epstein-Barr virus infection
ko05134 Legionellosis
ko03000 Transcription factors

ZFIN:

id description
ZDB-GENE-030131-6701 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within angiogenesis and cholesterol homeostasis. Predicted to be located in cytoplasm and nucleus. Is expressed in male organism. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human NFKB2 (nuclear factor kappa B subunit 2).

Ensembl:

ensembl_id ENSDARG00000038687

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00011760 False 3458 mRNA 0.47 24 22717366 22735547
TCONS_00011761 False 3338 mRNA 0.47 23 22717939 22735544
TCONS_00011762 False 849 mRNA 0.46 9 22719789 22725382
TCONS_00011763 True 840 mRNA 0.40 2 22731356 22733665

Neighbor

gene id symbol gene type direction distance location
XLOC_005947 SHLD2 coding upstream 2264 22698215 ~ 22715102 (+)
XLOC_005946 zgc:193505 coding upstream 39264 22675802 ~ 22678102 (+)
XLOC_005945 sncga coding upstream 44200 22659153 ~ 22673166 (+)
XLOC_005943 bmpr1aa coding upstream 97576 22555342 ~ 22619790 (+)
XLOC_005944 BX005174.1 coding upstream 134886 22571943 ~ 22582480 (+)
XLOC_005949 NA coding downstream 1568 22737115 ~ 22741976 (+)
XLOC_005950 dna2 coding downstream 86100 22821647 ~ 22839767 (+)
XLOC_005951 NA coding downstream 104462 22840009 ~ 22841394 (+)
XLOC_005952 hnrnph3 coding downstream 127969 22863516 ~ 22873184 (+)
XLOC_005953 tacr2 coding downstream 229321 22964868 ~ 22971495 (+)
XLOC_005937 BX649385.2 non-coding upstream 513728 22203524 ~ 22203638 (+)
XLOC_005936 BX649262.1 non-coding upstream 594161 22123090 ~ 22123205 (+)
XLOC_005932 ndst2a non-coding upstream 621432 21888214 ~ 22095934 (+)
XLOC_005954 NA non-coding downstream 296550 23032097 ~ 23046869 (+)
XLOC_005957 CR356222.1 non-coding downstream 491984 23227531 ~ 23240577 (+)
XLOC_005959 NA non-coding downstream 652946 23388493 ~ 23410510 (+)

Expression


Co-expression Network