Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_005965 |
| gene name | agt |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007124.7 |
| NCBI id | CM002897.2 |
| chromosome length | 52186027 |
| location | 23988442 ~ 23995876 (+) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| agt | Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity and regulation of apoptotic process. Predicted to act upstream of or within regulation of systemic arterial blood pressure by renin-angiotensin and vasoconstriction. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in liver. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (angiotensinogen). |
| id | name | namespace |
|---|---|---|
| GO:0003081 | regulation of systemic arterial blood pressure by renin-angiotensin | biological_process |
| GO:0010951 | negative regulation of endopeptidase activity | biological_process |
| GO:0005615 | extracellular space | cellular_component |
| GO:0004867 | serine-type endopeptidase inhibitor activity | molecular_function |
| id | description |
|---|---|
| ko04072 | Phospholipase D signaling pathway |
| ko04080 | Neuroactive ligand-receptor interaction |
| ko04924 | Renin secretion |
| ko04614 | Renin-angiotensin system |
| ko04925 | Aldosterone synthesis and secretion |
| ko04927 | Cortisol synthesis and secretion |
| ko04261 | Adrenergic signaling in cardiomyocytes |
| ko04270 | Vascular smooth muscle contraction |
| ko05200 | Pathways in cancer |
| ko05410 | Hypertrophic cardiomyopathy |
| ko05414 | Dilated cardiomyopathy |
| ko05415 | Diabetic cardiomyopathy |
| ko04931 | Insulin resistance |
| ko04933 | AGE-RAGE signaling pathway in diabetic complications |
| ko04934 | Cushing syndrome |
| ko01002 | Peptidases and inhibitors |
| ko03200 | Viral proteins |
| id | description |
|---|---|
| ZDB-GENE-030131-1205 | Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity and regulation of apoptotic process. Predicted to act upstream of or within regulation of systemic arterial blood pressure by renin-angiotensin and vasoconstriction. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in liver. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (angiotensinogen). |
| ensembl_id | ENSDARG00000016412 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00011794 | True | 1676 | mRNA | 0.46 | 5 | 23988442 | 23995876 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_005964 | sf3b5 | coding | upstream | 86710 | 23897975 ~ 23901732 (+) |
| XLOC_005963 | oprm1 | coding | upstream | 105465 | 23843712 ~ 23882977 (+) |
| XLOC_005962 | CR352246.1 | coding | upstream | 167142 | 23821186 ~ 23821300 (+) |
| XLOC_005961 | pcnx2 | coding | upstream | 253191 | 23669659 ~ 23735251 (+) |
| XLOC_005960 | il22ra2 | coding | upstream | 358415 | 23623346 ~ 23630027 (+) |
| XLOC_005966 | pgbd5 | coding | downstream | 27087 | 24022963 ~ 24056275 (+) |
| XLOC_005967 | abcb10 | coding | downstream | 267173 | 24263049 ~ 24277532 (+) |
| XLOC_005968 | acta1b | coding | downstream | 283145 | 24279021 ~ 24284442 (+) |
| XLOC_005969 | ccsapb | coding | downstream | 291217 | 24287093 ~ 24294103 (+) |
| XLOC_005970 | pdcd2 | coding | downstream | 384256 | 24380132 ~ 24383805 (+) |
| XLOC_005959 | NA | non-coding | upstream | 577932 | 23388493 ~ 23410510 (+) |
| XLOC_005957 | CR356222.1 | non-coding | upstream | 747865 | 23227531 ~ 23240577 (+) |
| XLOC_005954 | NA | non-coding | upstream | 941573 | 23032097 ~ 23046869 (+) |
| XLOC_005951 | NA | non-coding | upstream | 1147048 | 22840009 ~ 22841394 (+) |
| XLOC_005975 | NA | non-coding | downstream | 574744 | 24570620 ~ 24572928 (+) |
| XLOC_005978 | NA | non-coding | downstream | 601789 | 24597665 ~ 24649939 (+) |
| XLOC_005984 | AL929005.1 | non-coding | downstream | 832877 | 24828753 ~ 24828869 (+) |
| XLOC_005997 | BX530079.1 | non-coding | downstream | 1448108 | 25443984 ~ 25444523 (+) |
| XLOC_006005 | NA | non-coding | downstream | 1774123 | 25769999 ~ 25782811 (+) |
| species | gene id | symbol | gene type | chromosome | NCBI id | location |
|---|---|---|---|---|---|---|
| grasscarp (Ctenopharyngodon idella) | CI01000012_12902396_12904687 | AGT | coding | CI01000012 | null | 12902161 ~ 12905621 (-) |
