| Item | Value |
|---|---|
| gene id | AMCG00005118 |
| gene name | dpyd,dpydb,LOC106578501 |
| gene type | coding |
| species | bowfin (Amia calva) |
| category of species | ecological fish |
| Item | Value |
|---|---|
| chromosome id | CM030140.1 |
| NCBI id | CM030140.1 |
| chromosome length | 22460246 |
| location | 15642669 ~ 15662088 (+) |
| genome version | AmiCal1_2021_bowfin_Genome |
| symbol | description |
|---|---|
| dpydb | Predicted to enable several functions, including NADP binding activity; dihydropyrimidine dehydrogenase (NADP+) activity; and uracil binding activity. Predicted to be involved in thymidine catabolic process; thymine catabolic process; and uracil catabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in intestinal bulb; liver; pronephric duct; and yolk syncytial layer. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; dihydropyrimidine dehydrogenase deficiency; and pancreatic cancer. Orthologous to human DPYD (dihydropyrimidine dehydrogenase). |
| dpyd | Enables dihydropyrimidine dehydrogenase (NADP+) activity and protein homodimerization activity. Involved in nucleobase catabolic process and thymidine catabolic process. Located in cytosol. Implicated in acute lymphoblastic leukemia; dihydropyrimidine dehydrogenase deficiency; and pancreatic cancer. Biomarker of gallbladder cancer and pancreatic cancer. |
| description |
|---|
| PREDICTED: dihydropyrimidine dehydrogenase [NADP(+)] |
| id | name | namespace |
|---|---|---|
| GO:0019483 | beta-alanine biosynthetic process | biological_process |
| GO:0055114 | oxidation-reduction process | biological_process |
| GO:0006212 | uracil catabolic process | biological_process |
| GO:0006214 | thymidine catabolic process | biological_process |
| GO:0006222 | UMP biosynthetic process | biological_process |
| GO:0005737 | cytoplasm | cellular_component |
| GO:0004158 | dihydroorotate oxidase activity | molecular_function |
| GO:0046872 | metal ion binding | molecular_function |
| GO:0017113 | dihydropyrimidine dehydrogenase (NADP+) activity | molecular_function |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | molecular_function |
| GO:0000166 | nucleotide binding | molecular_function |
| id | description |
|---|---|
| K00266 | gltD; glutamate synthase (NADPH) small chain |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| AMCG00005118 | True | 639 | mRNA | 0.45 | 6 | 15642669 | 15662088 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| AMCG00005119 | NA | coding | upstream | 15410 | 15618611 ~ 15627259 (+) |
| AMCG00005110 | plppr5,LOC107739033,LOC107657749,LOC107677304,LOC107712819,LOC106578506 | coding | upstream | 150420 | 15465083 ~ 15492249 (+) |
| AMCG00005102 | NA | coding | upstream | 295291 | 15337268 ~ 15347378 (+) |
| AMCG00005103 | NA | coding | upstream | 332792 | 15309090 ~ 15309877 (+) |
| AMCG00005104 | NA | coding | upstream | 358219 | 15258397 ~ 15284450 (+) |
| AMCG00005117 | dpyd,LOC107590279,LOC107677268,LOC106568897,LOC106578501 | coding | downstream | 6 | 15662094 ~ 15680728 (+) |
| AMCG00005116 | NA | coding | downstream | 91094 | 15753182 ~ 15755418 (+) |
| AMCG00005120 | NA | coding | downstream | 317751 | 15979839 ~ 15991378 (+) |
| AMCG00005122 | cnn3,LOC108269615,LOC107739018,LOC108428967 | coding | downstream | 331278 | 15993366 ~ 16006829 (+) |
| AMCG00005121 | NA | coding | downstream | 376123 | 16038211 ~ 16043140 (+) |
| G145435 | NA | non-coding | upstream | 385006 | 15255889 ~ 15257663 (+) |
| G145418 | LOC106560501 | non-coding | upstream | 398423 | 15242385 ~ 15244246 (+) |
| G145398 | NA | non-coding | upstream | 489930 | 15142484 ~ 15152739 (+) |
| G145379 | NA | non-coding | upstream | 514098 | 15126586 ~ 15128571 (+) |
| G145369 | NA | non-coding | upstream | 545657 | 15094969 ~ 15097012 (+) |
| G145577 | NA | non-coding | downstream | 291527 | 15953615 ~ 15954678 (+) |
| G145593 | NA | non-coding | downstream | 374524 | 16036612 ~ 16047194 (+) |
| G145630 | NA | non-coding | downstream | 567200 | 16229288 ~ 16231853 (+) |
| G145731 | NA | non-coding | downstream | 1251927 | 16914015 ~ 16914225 (+) |
| G145744 | NA | non-coding | downstream | 1274739 | 16936827 ~ 16937075 (+) |
| AMCG00005105 | LOC102220226,LOC108442892 | other | upstream | 257858 | 15379599 ~ 15384811 (+) |
| AMCG00005060 | LOC106599426 | other | upstream | 1454340 | 14155155 ~ 14188329 (+) |
| G144940 | NA | other | upstream | 2861499 | 12780580 ~ 12781170 (+) |
| G144677 | NA | other | upstream | 3979301 | 11662681 ~ 11663368 (+) |
| AMCG00004935 | pbx1b,LOC108443834,LOC108272157,LOC106584178,LOC101069707,LOC105011758,LOC106599262 | other | upstream | 5627245 | 9948410 ~ 10015424 (+) |
| G145932 | NA | other | downstream | 2103169 | 17765257 ~ 17771525 (+) |
| AMCG00005199 | wdr78 | other | downstream | 3152941 | 18815029 ~ 18821642 (+) |
| AMCG00005232 | dock7 | other | downstream | 3813051 | 19475139 ~ 19530453 (+) |
| G146305 | NA | other | downstream | 3917485 | 19579573 ~ 19579807 (+) |
| G146519 | NA | other | downstream | 4520266 | 20182354 ~ 20184643 (+) |