XLOC_006188 (prkg1a)


Basic Information

Item Value
gene id XLOC_006188
gene name prkg1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 40815012 ~ 40955599 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012180
CGACACGGCAGGAAGCTACGCGTGCAGTTTCTTGACAGTACAGTTCACAATCTGGTTTCAGGCGAATTTGACTCCAGTCACAAAAGGGAAACTCCGCCTATACTGAAGACCCCGTGTGGATGAGGAGACAGTCGTACCCGGTATGGTTTATGTGTTTTTGGACACTGCACACAGGGATGTTTGGAACAGGAGTGACCGACAGCGGGAGCGACGCCGAATCCCGGTTTCAACTGTAAACACGTGTGTAGATCAGCTGTTTTTACACTGGAGCTTCACAAACAGAGCTCGCCTGGGCGCGTGACAGAGTTTGAGAGCGCGCCTGGTTGATTTCAACgggattaaagttttttttaactacCTCAGAATGAGTGACCTAGACGAAGACTTCGCGAAGATTTTAATGCTGAAGGAGGAGAGGATACGAGATCTTGAGAGGCGTTTGCTGGAGCGAGAAGACGAAATCAGCGAGCTGAAGAGAAAGCTGCACAAATGTCAGTCCGTTTTACCGAGCGCGCAGATCGGCCCGCGGACACACCGCGCGCAGGGAATATCAGCAGAACCGCAAACGCACCAGGATTTATCAAACCAAAGCTTTAGACGAGTTGCCAAATCGGACAGGTCAAAGGATCTGATCAAGTCAGCTATCCTGGACAATGACTTCATGAAGAATCTGGAAATGTCTCAAATCCAGGAGATCGTGGACTGTATGTATCCAGTGGACTATGACAAAAACAGCTGTATTATTAAAGAAGGCGATGTGGGCTCCCTCGTCTACGTCATGGAAGatggtAAGGTTGAAGTGACTAAAGAAGGACTGAAGCTGTGCACCATGGGACCAGGAAAAGTGTTTGGAGAGCTTGCCATCCTTTATAACTGCACCAGAACGGCCACTGTGAGAACGGTGTCCAGTGTGAAGTTATGGGCCATCGACAGACAGTGTTTCCAGACCATCATGATGAGGACGGGCCTAATCAAACATGCAGAGTACATGGAGTTATTGAAGAGTGTGCTGACGTTCCGGGGTCTTCCAGAGGAAATATTGAGCAAACTGGCTGATGTCCTGGAGGAGACCCACTATGAGGACGGCAACTACATCATTCGCCAGGGGGCAAGAGGAGACACTTTCTTCATTATCAGCAAAGGAAAGGTGACGATGACGAGAGAGGACTGTCCCGGTCAGGAGCCTGTTTACCTGCGGTCAATGGGGAGAGGAGATTCATTTGGGGAAAAAGCTTTGCAAGGGGAGGACATCAGAACGGCAAACGTCATCGCAGCAGAGACCGTCACCTGTCTTGTGATAGACAGAGAcTCTTACAAACATCTGATCGGAGGTCTGGAAGATGTTTCCAACAAAGGCTGTGAAGATGCTGAAGCAAAAGCAAAATACGAGGCAGAAAATGCCTTTTTCTCCAATCTGAACCTGTCTGACTTTAACATCATCGACACTCTTGGAGTTGGAGGATTTGGACGTGTGGAactgGTTCAGCTGAAGAGTGATGAAATGAAGACGTTTGCGATGAAGATCCTGAAGAAGCGTCACATTGTGGACACGAGACAGCAGGAGCACATCCGCTCCGAGAAGCTCATCATGCAGGAGGCACATTCAGATTTTATAGTCAGACTCTACCGCACATTTAAGGACAGTAAATACCTCTATATGCTGATGGAGGCCTGTTTAGGTGGAGAACTATGGACAATCCTGAGAGACCGGGGAAACTTTGACGATTCAACAACGCGATTTTACACAGCGTGTGTGGTGGAGGCCTTCGCTTATCTACATTCCAAAGGCATCATATACAGAGACCTCAAACCAGAGAACCTGATACTGGACCACAGAGGATACGCCAAGCTGGTGGATTTTGGCTTTGCTAAAAAGATCGGCTTTGGGAAGAAGACATGGACATTCTGTGGTACTCCAGAGTATGTGGCTCCAGAGATCATCCTGAATAAAGGACACGACATCTCTGCGGATTACTGGTCTCTCGGTATCCTCATGTATGAGCTGTTGACCGGCAGTCCTCCTTTTTCAGGACCAGATCCAATGAAAACATACAACATCATCCTTAGAGGCATCGATATGATTGAATTCCCCAAGAAAATAACCAAAAATGCTGCCAATCTCATCAAAAAGCTATGCAGAGACACTCCTTCTGAAAGATTAGGAAACTTGAAAAACGGTGTCAAAGACATCCAAAAGCACAAATGGTTTGAAGGGTTTAACTGGGACGGACTGAGGAAGGGGACGCTGATGCCCCCCATCATCCCTAATGTAACCTCATCCACAGACACCAGTAACTTCGACAGCTTTCCAGAGGACAACGAAGACCCACCGCCTGATGATAACTCAGGCTGGGATATAGACTTCTAAAAACtcatgtgcacaaacacacaacgcTGCTCACGCCAGACTGGATAAACCAACATGCTGCACTACTGTATGGACTGCAGGAGAAATGTGGAAAAAGCAAAAGGTTTGAGTCTATCGTGACTGTGAAGGAGATCCAGACACACGAAAAACTATCAAGtgagcatgtatgtgtgtgtgttcacatctGACCTATAATAACCACCTTTACTGTGAGATAACAGAGACGACAGTCCAATTACGGAAAAGGATGTGACCTCAATGACTTGTTCTTCTCCCTGATTGGCTGCGAACTCTTCATTCACCAATCCGTGTGCAGACTACTCTAAAGAAGACCAGGAGGCCAGACAGACCTGAATGTCGCTCTTCACGTAATACGGTTGTGGTCAAAATTAGTGGCACTCTTGGAAAATATGAGCAAAACTACCTGCATTTTTAAACTCTTTTTAGTAACAGAAATAGGTCCTTGAGCTaaaaccaatcaatcaaaatcTGTGCAACAAATCATTAGGAAATACAtgtgtttggtaacactttacaatagttTAAACAATAGAcacatagttcatttatttactaacatgaaccaatAATGACCAATACATTTATAACAGTCTTTATTCATCTCTGTTACGGTTAGTTTATGAAAATAGAGTTGACATGTTAAgtgttggattttaataatgcattagtaaatatttagctctgattaataaatgctgtgcaagta

Function

symbol description
prkg1a Predicted to enable ATP binding activity; cGMP binding activity; and cGMP-dependent protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Is expressed in several structures, including heart; nervous system; neural tube; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Orthologous to human PRKG1 (protein kinase cGMP-dependent 1).

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0016310 phosphorylation biological_process
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0030553 cGMP binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004692 cGMP-dependent protein kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1308 Predicted to enable ATP binding activity; cGMP binding activity; and cGMP-dependent protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Is expressed in several structures, including heart; nervous system; neural tube; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Orthologous to human PRKG1 (protein kinase cGMP-dependent 1).

Ensembl:

ensembl_id ENSDARG00000020656

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012180 True 3095 mRNA 0.45 19 40815012 40955599

Neighbor

gene id symbol gene type direction distance location
XLOC_006186 BX294129.1 coding upstream 6576 40754580 ~ 40808436 (+)
XLOC_006187 nkx1.2la coding upstream 39482 40770628 ~ 40775530 (+)
XLOC_006185 ankrd2 coding upstream 74007 40729618 ~ 40741005 (+)
XLOC_006184 hps1 coding upstream 98310 40686133 ~ 40716702 (+)
XLOC_006183 hpse2 coding upstream 146935 40501455 ~ 40668077 (+)
XLOC_006189 NA coding downstream 32816 40988415 ~ 40989361 (+)
XLOC_006190 dkk1a coding downstream 66903 41022502 ~ 41026398 (+)
XLOC_006191 NA coding downstream 841368 41796967 ~ 41799750 (+)
XLOC_006192 CABZ01066611.1 coding downstream 864218 41819817 ~ 41822485 (+)
XLOC_006193 NA coding downstream 866032 41821631 ~ 41854384 (+)
XLOC_006181 NA non-coding upstream 395708 40360160 ~ 40419304 (+)
XLOC_006179 NA non-coding upstream 484638 40327560 ~ 40330374 (+)
XLOC_006177 BX005216.1 non-coding upstream 845547 39969349 ~ 39969465 (+)
XLOC_006176 NA non-coding upstream 941384 39845264 ~ 39873628 (+)
XLOC_006194 NA non-coding downstream 903405 41859004 ~ 41863031 (+)
XLOC_006197 CABZ01080781.1 non-coding downstream 1086627 42042226 ~ 42042342 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000012_02251322_02337964 PRKG1A, PRKG1, PRKG1B coding CI01000012 null 2251137 ~ 2339368 (-)
bowfin (Amia calva) AMCG00002929 LOC106578950,LOC106589397 coding CM030139.1 CM030139.1 6556470 ~ 6575271 (+)