XLOC_006200 (ide)


Basic Information

Item Value
gene id XLOC_006200
gene name ide
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 42309688 ~ 42350160 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012189
TGCGTATATATTTTACATACTTcctaatatttattacatttaaattcgcGAAATGTACGTAAAGCCGCTGTGCGTGCTCTGAGATTGATTGGTTACGTCTGCAGGAATCATGGCGTCCTGACGTCTTAAGCTGAGTTTTGTTATCCAGCACTGAAGTATGCAGAAATGTGTTAGCCGGTGTGCCCTTACAGCGAGTTATCTTCCGATTTTATGATATTGTCCACGGTTTTCGGTCGAAGTATTAGACGTGTGTCGACTCTGTCCATCAGAATGAGTGATCCGGCTGTCAAGAGGGTGGTGAGTGATATCATTCGCTCTCCAGAAGACAAACGGGAGTATCGAGGACTCGAGTTTACAAATGGTCTGAAAGCCATTCTCATCAGTGACCCCACCACTGACAAATCATCAGCTGCCCTGGACGTCCACATGGGCTCTTTGTCAGATCCTGAGAACATTTCAGGCCTGGCCCACTTCTGCGAGCACATGCTGTTTCTGGGCACTGAGAAGTATCCCAAAGAGAACGAGTACAGCCAGTTTTTGAGTGAGCATGCCGGCAGCTCGAACGCCTTCACCAGCGGAGAGCACACCAATTACTACTTTGATGTATCCCATGAGCATCTGCAAGGGGCGTTGGACAGATTTGCCCAGTTCTTCCTCTGTCCCCTGTTTGATGAGAGCTGTAAGGACCGAGAGGTGAATGCAGTGGACTCTGAACATGAGAAGAACCTCATGAATGACGCATGGCGGTTGTTTCAGTTGGAGAAAGCCACTGGGAACCCAAAACACCCTTTTAGCAAATTTGGAACCGgcAACAAGTTAACCCTTGAGACCAGGCCATCTCAACAGGGCATTGATATCCGCGAGGAGCTGCTAAAGTTTCACTCTACCTATTATTCCTCCAACCTGATGGGATTGTGTGTGCTGGGCAGAGAGACGCTGGATGAATTGACATCAATGGTGGTGAAGCTTTTCGGAGAGGTGGAGAACAAGAATGTCCCTGTCCCAGAATTCCCTACACATCCTTTCCAGGAGGAACACCTGAGGCAATTCTATAAAGTGGTGCCAATCAAGGACATCAGAAACTTGTATGTGACCTTCCCTATACCAGACCTGCAGAAGTACTACAAATCAAATCCGGGTCATTATCTTGGCCACCTGATTGGACACGAGGGTCCAGGCAGTCTTTTGTCTGAGCTCAAATCTAAAGGATGGGTGAACACTCTAGTTGGAGGCCAGAAAGAAGGAGCCAGAGGATTCATGTTCTTCATTATTAATGTGGATTTGACAGAAGAGGGGCTGTTGCATGTCGAGGATATCATCTTCCACATGTTTCAGTACATTCAGAAGCTGCGGACGGAGGGCCCTCAGGAGTGGGTCTTTCAGGAGTGTAAGGATTTGAACACCGTGGCTTTCCGATTTAAGGATAAGGAACGTCCTCGTGGATACACGTCTAAAGTGGCTGGACTTCTGCATtACTATCCGCTGGAAGAAATTTTGGCTGCCGAATACTTGCTGGAAGAGTTCAGGCCAGACCTCATTGAGATGGTGCTTGATAAACTGAGACCAGAGAATGTCAGGGTTGCAGTTGTCTCCAAATCATTTGAAGGACAGACTGATCGGACTGAGGAGTGGTACGGCACACAGTATAAACAAGAAGCCATTACTGATGAAGCTATTAAGAAATGGGACAATGCAGACCTCAACGGAAAGTTTAAACTGCCAATGAAGAATGAATTTATCCCCACAAACTTTGAGATTTACCCTCTAGAGAAGGATTCCCCATCTGCCCCCACTTTAATAAAGgacaCTGCAATGAGCAAAGTTTGGTTCAAACAAGATGACAAGTTTTTCCTGCCTAAAGCTTGTTTAAACTTTGAGTTTTTCAGCCCGTTTGCATACGTGGACCCGTTGCATTGTAACATGGCGTATTTGTACCTTGAGCTGCTTAAGGATTCGCTGAATGAGTATGCATATGCAGCCGAGTTAGCCGGCCTGAGCTATGACCTTCAAAATACCGTCTATGGGATGTATCTGTCAGTCAAGGGTTATAATGACAAGCAACACATCCTGCTGAAGAAGATCATTGAGAAAATGGCCACGTTTGAGATCGATGAGAAGCGGTTTGATATCATTAAGGAAGCGTACATGAGGTCTTTGAATAACTTCCGCGCTGAGCAGCCTCACCAGCACGCCATGTATTACCTCCGTCTGCTCATGACTGAAGTGGCCTGGACCAAAGATGAGCTCAGAGACGCTCTGGATGATGTGACGTTACCTCGTCTGAAGGCGTTCATACCGCAGCTGTTGTCACGGTTACACATTGAAGCACTTCTGCATGGCAACATAACCAAACAGTCAGCTCTGGAAATGATGCAAATGCTGGAAGACACTCTCATTGAGCATGCTCACACTAAACCCCTTCTACCGAGTCAGCTGATTCGCTACAGAGAGGTGCAGGTTCCTGATGGTGGTTGGTATGTATACCAGCAGAGGAACGAGGTTCATAATAACTGTGGGATCGAGATTTACTATCAGACTGACATGCAGAACACCCATGAGAACATGCTGCTGGAGCTCTTCTGTCAGATCATCTCTGAGCCATGCTTCAACACGCTACGCACCAAAGAACAGCTGGGTTATATTGTGTTCAGTGGGCCTCGCAGGGCCAATGGGGTGCAGGGTCTGCGCTTCATCATCCAGTCTGAAAAAGCTCCCCACTACCTGGAGTCTCGTGTAGAGGCTTTCCTGAAGACCATGGAGAAGAGCGTGGAGGAGATGGGAGACGAGGCCTTTCAGAAACACATCCAGGCACTGGCCATTCGCCGTCTTGACAAACCCAAGAAGCTGGCGGCCGAGTGTGCAAAGTACTGGGGAGAGATCATCTCACAACAGTACAACTTCGACAGGGATAATATTGAAGTGGCTTACCTGAAGACACTGACAAAGGAACACATTATGCAGTTTTACAGGGACTTGTTGGCCATTGATGCCCCCAGAAGACATAAAGTGTCTGTGCATGTGCTGTCTAGAGAGATGGACTCTTGTCCACTGGTCGGAGAGTTTCCTGCTCAAAATGATGTCAATCTGGCTCCTGCTCCATCACTTCCTCAGcCATCATTGGTTCAGGATATGACTGAGTTCAAGAGGAGTCTGCCGCTGTTTCCCCTCACCAAACCTCACATCAACTTCATGGCTGCCAAACTGTGACCAGCATCATGGGATTGTCAGAGACGCCCCAATATGGAGCCAGTAACACCATagtctgtgtgtgagagtgtttctctctgtgtgtatgtgtgcctgtgtgcgtgcgtgcgtgtgtgtaagcAGGTATGGCCACAGCGCTGCTGCCTGTAACCCTTTCCGTTGTGCTCTGCGTCAGACATGCTCACCTGATTATCTCATAGATACAAAGAAAACATGCAATGGTTGGTTCATGTTGCTTCTGTCAGGAAATTTGTATATCTGTGTACTTTAGGAATCACTTGCTGGCCACGACAACAGTTCATGTCCAAATGCTGTTTCATTAATCTACACCACTGTTTAGGAAAAAACACAAGAAACTGCCTGGAGAGGCTTGTTCAGAGAAGTCTCTCCTGAAAAGGAAACGAAACTggccttaaaatgattttaatcaGCGATCAGGTTTTTCTGGCACCTTTTTTAAAACGTTTAATTTAAGTCATTTGCTTTTGAGTTGTTTTTAGGTTCTGTGCATGTTGGCAGAGTTTTATCTTTAAGGATGGTGATTGTAAATGCAAGGTGGTCACAACTTGAtggactttttgttttatttgagtttgaaaaaatataataaaccatttttaatataattttcttttcagttacTTTTGTCCTTTTAAAAATTTCATAATATACACCAAACCTGTTTTTTAAGCTAAACTCGGTTTCATAATAGTTTGTGAAAACCTTAagaatgttgtttgttttttcttaataaaaagtttaaact

Function

symbol description
ide Predicted to enable metal ion binding activity and metallopeptidase activity. Acts upstream of or within pancreas regeneration and type B pancreatic cell development. Predicted to be active in mitochondrion and peroxisomal matrix. Is expressed in myotome. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human IDE (insulin degrading enzyme).

GO:

id name namespace
GO:0042447 hormone catabolic process biological_process
GO:0031018 endocrine pancreas development biological_process
GO:0050435 amyloid-beta metabolic process biological_process
GO:0006508 proteolysis biological_process
GO:0043171 peptide catabolic process biological_process
GO:0051603 proteolysis involved in cellular protein catabolic process biological_process
GO:1990798 pancreas regeneration biological_process
GO:0003323 type B pancreatic cell development biological_process
GO:0005782 peroxisomal matrix cellular_component
GO:0005739 mitochondrion cellular_component
GO:0046872 metal ion binding molecular_function
GO:0004222 metalloendopeptidase activity molecular_function
GO:0003824 catalytic activity molecular_function

KEGG:

id description
ko05010 Alzheimer disease
ko01002 Peptidases and inhibitors

ZFIN:

id description
ZDB-GENE-070410-85 Predicted to enable metal ion binding activity and metallopeptidase activity. Acts upstream of or within pancreas regeneration and type B pancreatic cell development. Predicted to be active in mitochondrion and peroxisomal matrix. Is expressed in myotome. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human IDE (insulin degrading enzyme).

Ensembl:

ensembl_id ENSDARG00000075570

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012189 True 3973 mRNA 0.45 25 42309688 42350160

Neighbor

gene id symbol gene type direction distance location
XLOC_006199 opn3 coding upstream 44103 42245221 ~ 42265585 (+)
XLOC_006198 cdc42ep3 coding upstream 166051 42124566 ~ 42143637 (+)
XLOC_006197 CABZ01080781.1 coding upstream 267346 42042226 ~ 42042342 (+)
XLOC_006196 cyp1b1 coding upstream 290740 42011285 ~ 42018948 (+)
XLOC_006195 polr1b coding upstream 369221 41917606 ~ 41940467 (+)
XLOC_006201 cpeb3 coding downstream 56723 42406883 ~ 42472060 (+)
XLOC_006202 NA coding downstream 193800 42543960 ~ 42551434 (+)
XLOC_006203 mlh1 coding downstream 252246 42602406 ~ 42617639 (+)
XLOC_006204 mrpl14 coding downstream 326042 42676202 ~ 42679041 (+)
XLOC_006205 cdh23 coding downstream 412066 42762226 ~ 43011856 (+)
XLOC_006194 NA non-coding upstream 446657 41859004 ~ 41863031 (+)
XLOC_006193 NA non-coding upstream 455304 41821631 ~ 41854384 (+)
XLOC_006191 NA non-coding upstream 509938 41796967 ~ 41799750 (+)
XLOC_006189 NA non-coding upstream 1320327 40988415 ~ 40989361 (+)
XLOC_006206 NA non-coding downstream 469185 42819345 ~ 42819715 (+)
XLOC_006210 NA non-coding downstream 1240607 43590767 ~ 43610001 (+)
XLOC_006212 NA non-coding downstream 1504460 43854620 ~ 43855787 (+)
XLOC_006213 NA non-coding downstream 1523277 43873437 ~ 44113266 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G684071 NA unknown CI01180000 null 7506890 ~ 7525654 (-)
bowfin (Amia calva) AMCG00002865 ide coding CM030139.1 CM030139.1 4879277 ~ 4906202 (-)