CI01000001_09228393_09265951 (LRP1AB, LRP1)


Basic Information

Item Value
gene id CI01000001_09228393_09265951
gene name LRP1AB, LRP1
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000001
NCBI id null
chromosome length 13537560
location 9228366 ~ 9266098 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000001_09228393_09265951.mRNA
ACCCAAACCTTTTAATCATACACTCTGTGTGTATGTGTTTTTGGTTGGTTGAGCAGTTAAGCCCCTGTTGTGCTTTTATATTGTTCCAAGATGTCCTAAAGTCTTCTCTATAAGAGCATCAAAGGCTTTTCACTGTACACTGCACACATGGAAATCCCATACAATTTCTCTGATATCTCTAAGATAAGTGTGCACATACATAACAGAGACACTTGTAACAGACTAAGGCCGATCTTAGAGTTCGCTCATAACTGCACCATCATGGGCTGCCAATACAACTGTTCGGTGACAATGTCGGGTCCAAAGTGCTACTGCATGAACGGCTATGAGGTGGGAGAAGATGGAAAGACATGCAAAGACTTTAACGAGTGTGCAGTGTACGGGACTTGCAGTCAGACATGCACGAACTTAGATGGCTCCTACACCTGCAGCTGTGTGGAGGGCTACTTGCCTCAACCAGACAACCGCTCTTGCAAGGCCAAGAATGAACCTGTAGATCGGCATCCGTACCTCCTCATAGCCAACTCTCAGAACATCCAAGCCACCTCCCTGAGTGGAGCTAACCCCATCTCCATCAACACTAAGCAGACCACCGCTATGGACTTCATCTACGCCCAGGAGACCGTGTGCTGGATCCACATGGGTGACTCTCCCGCTGCCACCCAACTCAAGTGTGCCAAGTTCCCCAATGCCAAGAGCTTCACAGAGGAGAAGACCATCAACATCTCCCTCAGCCTGCACCATGTGGAGCAGATGGCCATTGACTGGCTGACGGGAAACTTTTACTTTGTGGATGATGTGGACGACCGCATATTTGTGTGCAGTAAAGACGGCTTGACCTGTGTCATCCTACTGGACCTGGAGCTCTATAATCCTAAAGGAATCGCACTGGATCCTGCCATGGGGAAAGTGTTCTTCACTGACTATGGCCAGATCCCGAAGGTGGAACGCTGCGATATGGACGGCCAAAACCGCACCAAACTTGTAGACAGCAAAATAGTCTTCCCTCATGGCATCACTCTGGACCTGGTCAGCAAGCTGGTGTATTGGGCCGACGCTTATCTGGATTACATTGAGGTGGTGGACTACGAAGGCAAGAACCGGCACACCATCATTCAGGGTTTACTGATTGAACATCTCTATGGTCTAACGGTGTTTGAAAACTATCTGTATGCCACCAACTCTGACAACGCCAACATGCAGCCCAAAACCAGTGTGATCAGAGTCAACCGATTCAACAGCTCTGACTTCCAGGTGGTGACACGCGTGGATAAAGGCGGCGCCCTTCACGTTTACCACCAGAGACGTCAGCCTGCAGTCCGCAGTCATGCGTGTGCACCCGATCAGTTTGGGAAGCCAGGCGGTTGCTCTGATATCTGTCTGCTGGGTAATAGTCACAAGAGCCGAACCTGCCGCTGTCGCTCTGGTTTCAGCCTTGGCAGTGATGGAAAGTCCTGCAAGAAACCAGAGCATGAGCTCTTCCTGGTGTACGGTAAAGGCCGGCCTGGTGTCATCCGCGGTATGGACATGCACGCTAAGGTGTATGACGAGCACATCATCCCCATTGAGAACCTGAATAACCCAAGAGCCCTGGACTTCCACGCTGAGACCGAATTCATCTATTTTGCTGATGCCACCAGCTACATCATCGGCCGCCAGAAAATTGATGGCACTGAGAGAGACATCATAGTGAAGGATGGTATTCACACAGTAGAAGGTATTGCTGTGGACTGGATGGGGCAAAACCTCTATTGGACTGATGATGGACCCAAAAAGACCATCAGTGTGGCCAAATTGGAAAAAGCCTCTCAGACCCGCAAAACTCTTATTGAGGGCAAGATGACCCATCCCAGAGCCATAGTAGTAGACCCTTCTCATGGAATGATGTATTGGAGTGACTGGGAGGAGGAGCCTAAAGAGACCAATCGTGGCAGTATAAAGAAGGCCTGGATGGACGGCTCAAACACTGGCATCCTGCTTACGTCTAAAACTGTGCTCTGGCCCAATGGCCTCAGCCTGGACATCCAGCAGGGCATCCTGTACTGGGTGGATGCGTACTACGACCGCATCGAGATGGTGCTTCTCAACACTACAGAACGCAGGACGGTATATGAAGGACAGGAGCTAAATCATCCCTTTGGCCTGTGCCATTATAAGAACTTCCTGTTCTGGAATGAGTACCGCGGTGGAGGAATCTACAAGCTGGACCAGAACACCAAAAAGGCCACATTGCTACGCAATGAACGACCACCAATCTACGAGATTCGCACCTACGATGCACAACAACAGCAAATCACAGGCTCCAATGTGTGCCGTGCCAATAATGGTGGCTGCAGCAGTCTGTGTCTGCTGACGCCCACGGGGCGCTCCTGCGCCTGTGCCGACGACCAAATACTAGACACTGACAACAAGACCTGTAAAGCAAACCCTTCCTACATACCTCCTCCACAGTGCCAGCCTGGAGAATTTGCCTGTAAGAATAACCGCTGTATTCAAGACCGCTGGAAGTGTGACGGGGACAATGACTGCCTGGACAACAGCGATGAGGCCCCTGAGTTGTGCCACCAGCACACCTGTCCTGCAGACCGCTTCAAGTGCCAAAATAACCGCTGTATCCCCCTGCGCTGGCTTTGTGATGGAGACAATGACTGTGGGAATGATGAAGATGAATCTAACAGCACCTGCTTGGCACGCACTTGTCCTTCTAATCAATACCCATGTGCCAGTGGCCGTTGTATCCCTGTCTCCTGGACATGTGACTTGGATGATGATTGTGGAGATCGCTCAGATGAACCAGCGTCTTGTGCATATCCTACCTGTTTCCCACTCACTCAGTTCACCTGTGCCAATGGACGCTGCATCAATGTCAACTGGCGTTGTGATAATGATAATGACTGCGGGGATAACAGTGATGAAGCCGGCTGCAGTCACTCGTGCTCCAGTGTGCAGTTTAAATGCAACAGCGGCCGCTGTATTCCAGAGTACTGGACCTGCGACGGAGACAACGACTGTGGAGATTACAGCGATGAGACTCATGCCAATTGTACCAATCAGGCCACGCGGCCTCCCGGCGGTTGCCACACGGATGAGTTCCAGTGCAGAATGGACGGCTTGTGTATTCCCATGCGATGGCGGTGCGATGGAGACACGGACTGCATGGACCTCAGCGACGAGAAGAACTGCGAGGGCGTCACGCATATGTGTGACCCTGCCGTAAAGTTCGCTTGCAAGGACTCAGCTCGCTGTATCAGTAAGGCCTGGGTGTGCGACAGGGACAGCGATTGCGAGGATAACTCAGATGAAGAAAACTGCGAGGCTCTTGAGTGCAAGCTCTCCCATCATGTTTGTGCCAGCAATGACTCCATCTGCCTACCTCCTGAGAAACTGTGTGACGGCAAGGATGACTGCCCTGATGGCTCGGACGAGAAGCTTTGCAATCTTTGCACGATGGATAATGGAGGCTGCAGCCACAACTGTACCATCGCACCTGGTGAGGGCATCCTGTGCTCCTGCCCAGCTGGCATGGAGCTGGATACCGACAACAAGACCTGCAAGATTCAGAACTTCTGCGCCAAGCATCTCAAGTGCAGCCAGCGCTGCGTGCAGGAGAAGGCCACTGTTAAGTGTGCCTGCTACGAGGGCTGGGCGCTCGGACCAGACAGCGAGAGCTGCAAGAGCACTGATCCATTCAAGCCCTTCATCATCTTCTCCAACCGGCATGAGATCCGTCGGATTGATTTGTACAAGGGCGAGTTCAGTGTACTGGTGCCTGGCCTGCGTAACACCATTGCCCTGGACTTTCACCTCAACCAGAGTGCCCTCTACTGGACTGATGTGGTGGAAGACAAGATCTATCGGGGAAAGCTGTCAGAAAACGGAGCTCTCACTAGTTTTGAGGTGGTGATCCAGTATGGTTTGGCCACTCCAGAGGGACTAGCTGTGGACTGGATCGCAGGAAATATCTACTGGGTGGAAAGTAATCTGGATCAGATCGAGGTGGCCAAGCTGGATGGTACAATGCGTACAACGCTGCTTGCCGGAGAGGTGGAGCATCCGCGTGCGATTGCGCTTGATCCAAGAGATGGTATTCTGTTCTGGACAGACTGGGACGCCAGCTCCCCCAGGATAGAGGCTGCGTCTATGAGTGGGGAGGGCCGTCGCACCATCCACAAAGAGACTGGGAATGGTGGCTGGCCTAACGGTCTTACTGTGGACTACCTAGAGCGCCGTATCCTGTGGATTGATGCAAGATCCGACGCCATCTACTCTGCGGCTTATGATGGTTCCGGCCTAATCGAGGTGCTTCGGGGTCATGAACACTTGTCACACCCCTTCGCAGTCACCATGTATGGAGGAGAGGTCTACTGGACGGACTGGAGGACCAATACTCTGGCTAAGGCCAACAAATGGACGGGACACAATGTGACAGTCGTCCAGAGAACAAACACTCAGCCGTTTGACCTTCAAGTGTTTCATCCATCTAGACAACCTCAGGCTCCAAACCCATGTGCGGCGAATGACGGGAAGGGGCCGTGTTCTCACCTGTGCCTCATCAACTACAACCAAACCTTCTCCTGTGCCTGTCCACACCTCATGAAGCTCAAGGCAGACAAGCACACTTGCTACGAGTACCGTCAGTTCCTGTTGTACGCTCGTCAGATTGAAATCAGAGGGGTGGATATTGATAATCCCTATTACAACTACATCATCTCTTTCACTGTGCCCGACATCGACAATGTTACAGTGGTGGATTATGATGCTCTGGAGCACCGCATCTACTGGTCTGATGTCCGCACTCAAACAATCAAAAGAGCCTTCATCAATGGGACTGGTGTTGAGACGGTTGTGTCAGCTGACCTTCCAAATGCTCAGGGTCTAGCTGTTGACTGGATCTCCAGAAACCTCTTTTGGACCAGCTATGATACGAATAAGAAGCAGATCAATGTTGCACGGCTGGATGGGTCCTTTAAGAACGCTGTAATCCACGGACTGGACAAGCCTCACTCGTTGGTGCTACATCCTATCCTGGGAAAGCTCTACTGGCTCGATGGGGACAACATCAGTATGGCCAACATGGACGGCACCAACCACACATTACTGTTCTCCAATCAGAAAGGCCCAGTGGGTCTGTCCATAGACTTTCACATGCAGCAGTTGTACTGGATCAGCTCAGGGAGCAGCACCATTAACCGCTGTAAGCTGGATGGCTCTGGACTGGAGATCATTGAGGGTGTGAAAGGAAAACTTACCAAAGCTACAGCCCTTGCCATCATGGGAAATAAGTTGTGGTGGGCCGATAAGGGAACAGATCAGATCGGTACATGTGACAAGAGCGATGGAGGCAACTGGAAGGTTCTCCGAAATAACACCTCACCCATGATGTATATGAAAATCTACAATGAGACTGTCCATCAAGGCATGGGCTCGTTTTTGCTCTACTCTGTGCATGAGGGCATCCGTGGCATTCCTCTGGACCCATTAGATAAATCTGATGCCCTGGTACCGGTGTCTGGCACCTCTCTTGCTGTGGGCATTGACTTCCATGCTGACAATGACACCATATACTGGGTTGACATGGGCCTGAGCACTATTAGCCGAGCCAAGAGAGACCAGACATGGAGAGAGGACATTGTGACCAATGGCATCGGACGTGTGGAAGGTATCACCGTTGACTGGATCGCAGGGTCTGGACAAACCTCGTGCCATTACTGTACATCCAGAGAAAGGGAAAAACTGATCTTGGACTCATGTATTTGTTTGTACAGGTATCTGTTCTGGACGGAGTGGGGTCAGTATCCACGTATCGAAAGGTCTCGTCTGGATGGTTCGGAGAGAATAGTTCTTGTCAATGTCAGCATCAGCTGGCCCAATGGCATCTCCATTGATTACCAGGAGGGCCTTCTGTATTGGTGTGATGCCCGCACAGACAAAATTGAACGCATAAATCTGGAGACTGGAGAAAACCGTGAGCTGGTGCTGTCTAGTAACAACATGGACATGTTTGCTGTTTCTGTCTTTGAGGAATACATCTACTGGAGTGACAGGACACATGCCAATGGCTCCATCAAGAGAGGAAACAAGGACAACGCCACAGATATGGTCTATCTAAGAACAGGCATTGGTGTGCAGCTCAAAGACATTAAAGTCTTCAATCGTGCTAGGCAGCAAGGTACCAACGTCTGTAAGGTGAACAATGGTGGTTGTGAACAGCTGTGTCTGTTCCGTGGTAATGGCAATCGTACCTGTGCCTGCGCACACGGCATGCTGGCAGAAGATGGCCACAGTTGCAGGGACTATGATGGCTACCTCCTCTACTCGGAGCGCACGATACTGAAGAGCATCCACCTGTCGGATGAAACAAACCTCAATGCTCCCATTAAACCCTTCGAAGACCCAGAGCACATGAAGAACGTAATCGCCCTTACCTTCGACTACAGAGGCGGTGGTGGAAAGGGAGCCAACCGGATCTTCTACAGCGACATCCACTTCGGTAACATTCAGCAGATCAGCGATGACGGCTCTGACCGCAAGACCATAGTAGAGAGTAAGTGTTCAGTCTTTTTATTCATGTTCATTGTTCTGTATTGTGCAAAGCATCTGGATGAGGGTAACAAGAATATGTGTAAAAAAAATTATAATTAATGAAACCAATCACTTGAAAAAAATAAA

Function

symbol description
lrp1ab Predicted to enable calcium ion binding activity. Acts upstream of or within regulation of vasculature development. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; keratosis pilaris atrophicans; myocardial infarction; and sciatic neuropathy. Orthologous to human LRP1 (LDL receptor related protein 1).
lrp1 Enables alpha-2 macroglobulin receptor activity; apolipoprotein binding activity; and clathrin heavy chain binding activity. Involved in several processes, including amyloid-beta clearance by cellular catabolic process; amyloid-beta clearance by transcytosis; and positive regulation of lysosomal protein catabolic process. Located in basolateral plasma membrane and early endosome. Part of receptor complex. Implicated in Alzheimer's disease; keratosis pilaris atrophicans; myocardial infarction; and sciatic neuropathy.

GO:

id name namespace
GO:0016020 membrane cellular_component

KEGG:

id description
K04550 LRP1, CD91; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000001_09228393_09265951.mRNA True 6669 mRNA 0.51 38 9228366 9266098

Neighbor

gene id symbol gene type direction distance location
CI01000001_09213449_09223894 LRP1AB, LRP1 coding downstream 4016 9213431 ~ 9224350 (-)
CI01000001_09032204_09038149 IDH3G coding downstream 190217 9032204 ~ 9038149 (-)
CI01000001_08990605_08998643 AVPR2AA coding downstream 228832 8990590 ~ 8999534 (-)
CI01000001_08942877_08948672 NA coding downstream 279694 8942780 ~ 8948672 (-)
CI01000001_08904658_08904945 NA coding downstream 323128 8904644 ~ 8905238 (-)
CI01000001_09270954_09281725 NA coding upstream 3604 9269702 ~ 9282511 (-)
CI01000001_09322428_09325859 NA coding upstream 56032 9322130 ~ 9325977 (-)
CI01000001_09356265_09365557 SENP1 coding upstream 89069 9355167 ~ 9366268 (-)
CI01000001_09367413_09370794 NA coding upstream 100387 9366485 ~ 9370794 (-)
CI01000001_09374272_09375120 NA coding upstream 106404 9372454 ~ 9375120 (-)
G18508 NA non-coding downstream 8439 9207983 ~ 9219927 (-)
G18646 NA non-coding downstream 84675 9143103 ~ 9143691 (-)
G18645 NA non-coding downstream 85483 9142615 ~ 9142883 (-)
G18499 NA non-coding downstream 122779 9104525 ~ 9105587 (-)
G18637 NA non-coding downstream 139974 9088076 ~ 9088392 (-)
G18700 NA non-coding upstream 53365 9319463 ~ 9320136 (-)
G18698 NA non-coding upstream 88048 9354146 ~ 9355051 (-)
G18694 NA non-coding upstream 134752 9400850 ~ 9407239 (-)
G18771 NA non-coding upstream 244894 9510992 ~ 9511210 (-)
G18223 NA other downstream 1299849 7926104 ~ 7928517 (-)
G18023 NA other downstream 1470846 7756501 ~ 7757520 (-)
G17911 NA other downstream 1975112 7251311 ~ 7267952 (-)
CI01000001_06932075_06937182 NA other downstream 2291143 6931621 ~ 6937231 (-)
G17789 NA other downstream 2337952 6837525 ~ 6890414 (-)
CI01000001_09804494_09811219 NA other upstream 543559 9804429 ~ 9811219 (-)
G20136 NA other upstream 1272929 10539027 ~ 10539850 (-)
CI01000001_10862471_10864514 NA other upstream 1596127 10862225 ~ 10865770 (-)
G20230 NA other upstream 1756029 11022127 ~ 11028777 (-)
G20319 NA other upstream 1844739 11110837 ~ 11114747 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_022377 lrp1ab coding NC_007134.7 CM002907.2 25452656 ~ 25686954 (-)
bowfin (Amia calva) AMCG00008788 LOC106565466 coding CM030126.1 CM030126.1 11800161 ~ 11878186 (-)