CI01000005_05919567_05933578 (GCLC)


Basic Information

Item Value
gene id CI01000005_05919567_05933578
gene name GCLC
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000005
NCBI id null
chromosome length 7630583
location 5918402 ~ 5933856 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000005_05919567_05933578.mRNA
TTATAAAAAAGAAAGAAAAAAAAGAAAGTAACCATTAGGGAACGTTCTGTATAATGGTAATAATAATAATAATAATTATAAAAGAAAATAACCATTAGGGAACGTTTTGTGTAAGTAATTAATTGTTATAAAAACATTAAAAATAAAAAATAACAATTATGGATAGTTCTGTATAATGGTTATTAAAAAAACATTAGGTAATGTTCTGTATAAGCTATTAACGGTTATTAAAAAAAAAAAAAAACATTAGGGAGCGTGCTGTATAAGTTACTGTATTTGTCTCAAATATCATGCAGCGAATGTTCTGGAAACGTTATTTTATGGTTGTAAAAATTAAACCCTAAAAAGAACGTTCTTTGGAAGTTATAATTTGTTGCACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACGGGAAACAAATACTGCTAACGTTAAGGGAACGTTTTGTGTTTGCTGACCTTGGTGTTGCTCCAACCATAACCCTAATATTTCATAACCAGCATATTCCAAATACACGCAATTTAAAAATTTTTTTTTTTTTTAATACAAATAGGTGCAATATTTGATACGTTGCTTAAAAAAAGCAGCATTTTAAATGCTACCTTCATTTAAGAAGGAAAAGACCAAATAATAAAACAACCGCTAAACAAAATGTCCTTAGTTAAACAAACACCGTATTCTGCTTCTTACGTTTTGCATCGTCACGATTACAAAAGCACATTCAATCTGATCGGCTTCCACAGCTGCGCACGTTACCTTCACCACACCGTCAACAGCGCACAATGAAGAAGAAGGGATTGCTGAGTCATAACATGACGTCCCGCAACGACACAGTCACGTGTTCTCAATACAGGCAAAGTGTCTGTGCGGGAGGAAAGGACTGACATATAACTCGCGCACTCCGATCAAATATCACCTGCTCGCAACTCGAGACCGCTTTATTCCCTTCTAACGCGAGGTGTCGTGAACCCGTCCGCGAGAACCGCTTGGAAGCACAGAGCGAATACTTCCGTGTTTAAAAAAAGAATCATTTAAGGCCTAGCGTGCGCGCTCGCGAGCATTATATTATCGTTTATATCAAGTGTGAGACACGTGTCGCGCGGTGGACGAGAAGCTGAAGTTGAAGTCCATAACAATAAGCGAGGGTTCGTAGGTTTGTGATATGGGCTTACTGTCACAAGGGTCACCGCTCAACTGGGAAGAGACCAAGAAACATGCTGACCACGTTAGAAAGCACGGCATCCTTCAGTTCCTCAACATCTACAATAAGGTCAAAGATCGGCAGAAGGATGTGCTGAAATGGGGAGACGAGGTGGAGTACATGTTGGTGGAAATGGATGAAAGACATGAAAAAGTCCGTCTGGTTCTGAACGGGAAGGATGTTCTGGAAACCCTTCAGGAAAAGGGTGAAAAGATCAACCCCAACCACCCTACTCTGTGGAGGCCGGAGTACGGCAGCTACATGATCGAAGGAACGCCGGGACAGCCGTACGGAGGGACGATGTCGGAGTTCAACACGGTAGAAGACAATATGGGAAAGCGGAGGAGAGAGGCCTCATCTGTGCTCAGCCAGAACCAAACTCTCCTCACAGTTACGTCATTCCCCAGGTTAGGCTGCCCAGGCTTCACGCTGCCAGAATACAAACCCACACCTGTCGAGAAAGGGGTGTCCAAATCGCTTTTCTTCCCTGATGAGGCCATCAACAGACACCCTAGATTCAGCACTCTGACCAGAAACATACGCCACCGGAGGGGCGAAAAGGTGGTGATTAACGTACCAATTTTTAAAGATAAAAACACCCCATCTCCGTTTGTGGAGCCGTTTCCAGAAGATGATGGAGAAGCTGCCCGGGGTGCCCTGCCTGATCACATCTACATGGACGCCATGGGCTTTGGCATGGGAAACTGTTGCCTGCAGGTGACCTTCCAAGCTTGCAGCATCAGAGAGGCGCGCTACCTTTATGACCAACTGGCTGTTTTCTGTCCCATAGTGATGGCTCTCAGTGCTGCCTCACCGTTCTATCGCGGATTCGTGTCAGACATCGACTGCCGTTGGGGAGTGATCTCTGCGTCTGTGGATGACCGGACCAGAGAGGAGAGGGGCCTGGAGCCGCTGAAAAACAACAAATTCAGGATCAACAAATCGAGGTATGATTCGATTGACAGCTACCTCTCCTGCTGTGGTGAGAAATACAATGACATTGAGCTGACCATCGATGAAGAGATCAACAAACAGCTCCTCGATGCAGGCATTGACAAACTGCTGGCACAGCACATCGCACATCTCTTCATCCGCGACCCGCTGTCGCTCTTCCAGGAGAAGATTCATTTGGATGATGAGAACGAATCGGACCACTTCGAGAATCTTCAGTCAACCAACTGGCAGACAATGAGGTTCAAGCCTCCCCCTCCAAACTCTGACATCGGATGGAGAGTGGAGTTCCGTCCCATGGAGGTATTAAACAAACAGCTGTCTGTGTGCCAAATGATGCAAGCAGACGCGGCCTGACTGACTGTGTGCTTAGCAAAGCATATATATATACAGGGTGCCATTTGAGGGGAAAAAAGGCAGAGGGGGGATGTTTTTGAAACGTTTTTTTATTCATGAAAGTAAATCACAAACCACAGTGCAGCTGTTAAATGAACTTTAGTGAAAAAATATCTAAACATTTTGGAAAAGGAATATTTTAATCCATTTTTACATTTTCATCAAGTTTCACTCTTATGACTTGTCCTTTCCTCGTTGGGAAGCTCTCATACACATTACATATATATTACATTTACATA

Function

symbol description
gclc Predicted to enable anion binding activity; glutamate-cysteine ligase activity; and magnesium ion binding activity. Predicted to be involved in several processes, including alpha-amino acid metabolic process; cell redox homeostasis; and glutathione biosynthetic process. Predicted to be part of glutamate-cysteine ligase complex. Is expressed in several structures, including alar plate midbrain region; gut; intermediate cell mass of mesoderm; midbrain; and sensory system. Human ortholog(s) of this gene implicated in cystic fibrosis; glutamate-cysteine ligase deficiency; hemolytic anemia; and myocardial infarction. Orthologous to human GCLC (glutamate-cysteine ligase catalytic subunit).

GO: NA

KEGG:

id description
K11204 GCLC; glutamate--cysteine ligase catalytic subunit

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000005_05919567_05933578.mRNA True 2790 mRNA 0.43 11 5918402 5933856

Neighbor

gene id symbol gene type direction distance location
CI01000005_05909951_05914160 KLHL31 coding upstream 3357 5909874 ~ 5915045 (+)
CI01000005_05607239_05610450 NA coding upstream 307938 5606550 ~ 5610464 (+)
CI01000005_05581753_05591911 HMGCLL1 coding upstream 326398 5581753 ~ 5592004 (+)
CI01000005_05538096_05558622 BMP5 coding upstream 359747 5537380 ~ 5558655 (+)
CI01000005_05527581_05534620 NA coding upstream 382811 5527581 ~ 5535591 (+)
CI01000005_05935743_05940360 GCLC coding downstream 1755 5935611 ~ 5941127 (+)
CI01000005_05946561_05962719 ELOVL5 coding downstream 12705 5946561 ~ 5962771 (+)
CI01000005_05984685_05985981 NA coding downstream 50829 5984685 ~ 5986158 (+)
CI01000005_05998137_06003757 PNO1, PNO1.L coding downstream 64281 5998137 ~ 6003909 (+)
CI01000005_06013685_06015621 NA coding downstream 79266 6013122 ~ 6015839 (+)
G39399 NA non-coding upstream 28300 5889878 ~ 5890102 (+)
G39348 NA non-coding upstream 84227 5833835 ~ 5834175 (+)
G39328 NA non-coding upstream 114746 5803376 ~ 5803656 (+)
G39310 NA non-coding upstream 146694 5770270 ~ 5771708 (+)
G39308 NA non-coding upstream 153050 5738292 ~ 5765352 (+)
G39381 NA non-coding downstream 84870 6018726 ~ 6022310 (+)
G39379 NA non-coding downstream 100438 6034294 ~ 6038148 (+)
G39562 NA non-coding downstream 157042 6090898 ~ 6091138 (+)
G39563 NA non-coding downstream 157743 6091599 ~ 6091818 (+)
G39564 NA non-coding downstream 160967 6094823 ~ 6095047 (+)
CI01000005_04735429_04736817 COX20 other upstream 1181545 4735346 ~ 4737082 (+)
G37392 NA other upstream 2194899 3722744 ~ 3723503 (+)
G36291 NA other upstream 4257370 1659733 ~ 1661032 (+)
G36223 NA other upstream 4380598 1503143 ~ 1537804 (+)
G35533 NA other upstream 5394621 491908 ~ 523781 (+)
G39930 NA other downstream 1063688 6997544 ~ 6998340 (+)
CI01000005_07600541_07600974 NA other downstream 1664133 7600541 ~ 7602964 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_005709 gclc coding NC_007124.7 CM002897.2 2357637 ~ 2392664 (+)