serpinc1 (serpinc1)


Basic Information

Item Value
gene id serpinc1
gene name serpinc1
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035901.1
NCBI id CM008304.1
chromosome length 40584741
location 14005926 ~ 14016985 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022669643.1
GATGTGCTCTGCAGGGCACTGACCTGCTGCAGACGACGCAGTGTCCCCTGTGTCCACTCGCTGCTTTACAACGATAGAGAAACGCTGCCCTCtgttttataaaggatttaaagCCTCAGCAGttcAGGCATCATGAAGTTGTGGACATGTCTAGGAGCTCTCTGGATCCTCTCTATCTGCTCAGTTCAGGCTGCCGTAGACATCTGCAGCGCTAAGCCCAAAGACCTGCCTCTGCAGCCGGTCTGCATCTACCGCAACCCAAACGTGCACGATCATGAAGCAGCACCAACCGAGAAACCCGCTGTGAAGGTCCTGGAGAAAGCCTCAGAAAAAGCCCACGGGAAGATGCTAGAGAAGATCCCAGAGTCCACCAACCCTCGAGTGTATGAGCTGTCCAAAGCCAACGGCCGCTTCGCCCTGTCCCTCTTTAAGCAGCTCTCTAAGGGAAAACCTCATGAAGAAAACATCTTCATGTCCCCCCTCAGCATCTCCACGGCCTTCGCCATGACCAAGCTGGGGGCCTGCAATAGCACACTGGAGCAGATCATGAAGGTCTTCGAGTTCGACACTATAAAGGAGAAAACGTCAGATCAGGTTCACTTTTTCTTCGCTAAGCTGAACTGTCGCCTCTACcgcaaaaaacacaacactgtGGAGCTGGTCTCGGCCAACCGCCTGTTCGGAGAGCAGTCCCTGAACATCAACGAGAACTTCCAGAACATCAGCGAGGTCGTCTACGGGGCCAAGCTGATGCCACTCAACTTTAAGGAGAAACCTGAAATATCGAGACTGAAAATCAACCAGTGGATCTCTGAGAAGactaaaggtaaaataaacgaCACTCTGCCGCAGGGATCAATAGACGCCACTGCTGTAATGGTCCTGGTGAACACCATCTACTTTAAGGGCCAGTGGAAGAATAAGTTTGACAAAAAGGATGTCATGTCGTTACAATTCCATGTGAGCTCTACAAAGAAGTGTCAGGTTCACATGATGTACAAGGAGGCAAAGTTCCAGTATAAGAAGTTTCCAGAGGATAAGGtgaaggtgctggagctgcccTACAATGGAGGCGGGATTTCCATGGTGCTGGTGCTACCAATGAAAGATTCCAACCTTACTGAGGTGGAAAAGATCATAACCTATAGCAAACTGACCAACTGGACGAACACCATGTCTGAGACCACCGTGGCGGTTCAGATCCCCCGTTTCCGCATCGAGGACAGCTTCAGCCTAAAGGAGAAGATGCGGGACATGGGCCTCAACCATCTCTTCAGCGCAGAGCACGCCAGCCTCCCAGGCATCGTTGAGGGCGTCGACAACGGCATTTACATCTCTGACGCTTATCACAAGGCTTTCCTCGAAGTGAACGAGGAGGGCAGTGAGGCAGCAGCTGCCACGGCTGTTGTGGCACTCGGCCGCTCCCTCAACGTGAACCGCGAGAGTTTTGTCGCCAACAAGCCCTTCCTGCTCTTCATCCGGGAAGccaccatcaacaccatcatcttCGCTGGCCGCATATCCAACCCCTGCAAAAGCGGCTAAAGCACTTTGTTCCTTTTATTTGAAATGTTACCAGCactggaggagaagaaggagggaGAGGAAAGCCAGTTGTTATCCTCATCCATCAGACAACGAGATGGTTTTTCATCACAAATAAAGATCTTTTCGCCATGTCA

Function

symbol description
serpinc1 Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within cellular response to estrogen stimulus and regulation of blood coagulation. Predicted to be active in extracellular space. Is expressed in liver; yolk; and yolk syncytial layer. Used to study disseminated intravascular coagulation. Human ortholog(s) of this gene implicated in antithrombin III deficiency; disseminated intravascular coagulation; intermediate coronary syndrome; thrombosis; and toxic shock syndrome. Orthologous to human SERPINC1 (serpin family C member 1).

NR:

description
antithrombin-III-like isoform X1

GO:

id name namespace
GO:0030162 regulation of proteolysis biological_process
GO:0010951 negative regulation of endopeptidase activity biological_process
GO:0071391 cellular response to estrogen stimulus biological_process
GO:2000266 regulation of blood coagulation, intrinsic pathway biological_process
GO:0005615 extracellular space cellular_component
GO:0008201 heparin binding molecular_function
GO:0004867 serine-type endopeptidase inhibitor activity molecular_function

KEGG:

id description
K03911 SERPINC1, AT3; antithrombin III

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022669643.1 True 1682 mRNA 0.51 8 14005926 14016985

Neighbor

gene id symbol gene type direction distance location
dph5 dph5,LOC107715097,LOC106613590 coding downstream 92714 13892691 ~ 13913212 (-)
dbt dbt,LOC107715105,LOC107588055,LOC107669841,LOC107653638,LOC107592709 coding downstream 312560 13683295 ~ 13693366 (-)
LOC103036543 NA coding downstream 322726 13680717 ~ 13683200 (-)
lrrc39 lrrc39,LOC107592708,LOC107653639 coding downstream 326842 13672906 ~ 13679084 (-)
LOC103034756 osbpl1a,LOC108429508,LOC108271178,LOC107592705 coding downstream 341039 13630221 ~ 13664887 (-)
rc3h1 rc3h1,LOC108429496 coding upstream 9788 14026773 ~ 14052048 (-)
stil NA coding upstream 36538 14053523 ~ 14073444 (-)
LOC103040192 NA coding upstream 128150 14145135 ~ 14148466 (-)
LOC103042854 LOC103042854,LOC108424983 coding upstream 395995 14412980 ~ 14421108 (-)
LOC103043174 lpl,LOC108271131,LOC107588078,LOC107715086 coding upstream 414296 14431281 ~ 14441363 (-)
G42430 s1pr1,LOC107715096,LOC107592715,LOC107669844 non-coding downstream 20865 13981970 ~ 13985061 (-)
G42415 NA non-coding downstream 139587 13861654 ~ 13866339 (-)
G42414 NA non-coding downstream 166918 13837030 ~ 13839008 (-)
G42411 NA non-coding downstream 171727 13830953 ~ 13834199 (-)
G42375 NA non-coding downstream 210609 13791891 ~ 13795317 (-)
G42465 NA non-coding upstream 114730 14131715 ~ 14134393 (-)
G42500 mrpl54,LOC102788358 non-coding upstream 289738 14306723 ~ 14309624 (-)
G42519 NA non-coding upstream 328836 14345821 ~ 14346308 (-)
LOC103043998 NA non-coding upstream 439862 14456847 ~ 14459618 (-)
G42674 NA non-coding upstream 599431 14616416 ~ 14666365 (-)
tm2d1 tm2d1,LOC107669801,LOC107653653,LOC107715116,LOC106574044,LOC107731529 other downstream 843121 13142373 ~ 13162805 (-)
nr2c2ap nr2c2ap,LOC107554809,LOC107687739,LOC107728548 other downstream 2232824 11767698 ~ 11773102 (-)
borcs8 borcs8,LOC107599453,LOC107554813,LOC107728595 other downstream 2243665 11756447 ~ 11762261 (-)
mef2b mef2b other downstream 2274030 11720126 ~ 11731896 (-)
LOC103041480 NA other downstream 2326907 11618444 ~ 11679019 (-)
fam32a fam32a,LOC107757479 other upstream 286555 14303540 ~ 14305976 (-)
G42516 NA other upstream 318945 14335930 ~ 14339171 (-)
G42661 NA other upstream 445688 14462673 ~ 14526890 (-)
G42712 LOC108438667,LOC105021477,LOC107674533 other upstream 843569 14860554 ~ 14861338 (-)
socs7 socs7 other upstream 932899 14949884 ~ 14966800 (-)

Expression


Co-expression Network