| Item | Value |
|---|---|
| gene id | XLOC_012067 |
| gene name | vax1 |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007128.7 |
| NCBI id | CM002901.2 |
| chromosome length | 53461100 |
| location | 21432693 ~ 21442279 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| vax1 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including camera-type eye morphogenesis; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and regulation of retinal ganglion cell axon guidance. Predicted to be active in nucleus. Is expressed in several structures, including anterior neural rod; eye; forebrain; forebrain neural keel; and optic vesicle. Human ortholog(s) of this gene implicated in syndromic microphthalmia 11. Orthologous to human VAX1 (ventral anterior homeobox 1). |
| id | name | namespace |
|---|---|---|
| GO:0061386 | closure of optic fissure | biological_process |
| GO:0090259 | regulation of retinal ganglion cell axon guidance | biological_process |
| GO:0021554 | optic nerve development | biological_process |
| GO:0006355 | regulation of transcription, DNA-templated | biological_process |
| GO:0006357 | regulation of transcription by RNA polymerase II | biological_process |
| GO:0030182 | neuron differentiation | biological_process |
| GO:0007275 | multicellular organism development | biological_process |
| GO:0007411 | axon guidance | biological_process |
| GO:0007417 | central nervous system development | biological_process |
| GO:0007420 | brain development | biological_process |
| GO:0060041 | retina development in camera-type eye | biological_process |
| GO:0060042 | retina morphogenesis in camera-type eye | biological_process |
| GO:1902254 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator | biological_process |
| GO:0005634 | nucleus | cellular_component |
| GO:0043565 | sequence-specific DNA binding | molecular_function |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | molecular_function |
| GO:0003677 | DNA binding | molecular_function |
| GO:0003700 | DNA-binding transcription factor activity | molecular_function |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | molecular_function |
| GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding | molecular_function |
| id | description |
|---|---|
| ZDB-GENE-030904-9 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including camera-type eye morphogenesis; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and regulation of retinal ganglion cell axon guidance. Predicted to be active in nucleus. Is expressed in several structures, including anterior neural rod; eye; forebrain; forebrain neural keel; and optic vesicle. Human ortholog(s) of this gene implicated in syndromic microphthalmia 11. Orthologous to human VAX1 (ventral anterior homeobox 1). |
| ensembl_id | ENSDARG00000021916 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00023804 | False | 2555 | mRNA | 0.46 | 3 | 21432693 | 21441464 |
| TCONS_00024893 | True | 1281 | lncRNA | 0.46 | 2 | 21432693 | 21442279 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_012066 | atp6v1ba | coding | downstream | 14353 | 21372291 ~ 21418340 (-) |
| XLOC_012065 | shtn1 | coding | downstream | 63918 | 21311401 ~ 21368775 (-) |
| XLOC_012064 | hspa12a | coding | downstream | 152508 | 21220934 ~ 21280185 (-) |
| XLOC_012063 | NA | coding | downstream | 212214 | 21213422 ~ 21220479 (-) |
| XLOC_012062 | abhd12 | coding | downstream | 232287 | 21154576 ~ 21200406 (-) |
| XLOC_012068 | gpr26 | coding | upstream | 164960 | 21607239 ~ 21617618 (-) |
| XLOC_012069 | hmx2 | coding | upstream | 339764 | 21782043 ~ 21784152 (-) |
| XLOC_012070 | hmx3a | coding | upstream | 348327 | 21790606 ~ 21793113 (-) |
| XLOC_012071 | si:ch211-208g24.8 | coding | upstream | 384546 | 21826825 ~ 21832190 (-) |
| XLOC_012072 | cuzd1.2 | coding | upstream | 391440 | 21833719 ~ 21859164 (-) |
| XLOC_012061 | AL929290.1 | non-coding | downstream | 302316 | 21130261 ~ 21130377 (-) |
| XLOC_012055 | NA | non-coding | downstream | 509165 | 20900590 ~ 20923528 (-) |
| XLOC_012054 | BX927186.1 | non-coding | downstream | 729396 | 20703179 ~ 20703297 (-) |
| XLOC_012051 | NA | non-coding | downstream | 758802 | 20670398 ~ 20673891 (-) |
| XLOC_012073 | NA | non-coding | upstream | 421376 | 21863655 ~ 21864182 (-) |
| XLOC_012082 | NA | non-coding | upstream | 1042526 | 22484805 ~ 22504384 (-) |
| XLOC_012083 | BX511218.1 | non-coding | upstream | 1079357 | 22521636 ~ 22525745 (-) |
| XLOC_012086 | NA | non-coding | upstream | 1244891 | 22687170 ~ 22689787 (-) |
| XLOC_012087 | BX548077.1 | non-coding | upstream | 1343895 | 22786174 ~ 22786291 (-) |