XLOC_001210 (uchl1)


Basic Information

Item Value
gene id XLOC_001210
gene name uchl1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 22647756 ~ 22652424 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001937
TTTTAAGAGAAATGAGCAGAGCTGAATTGAGTTATTCAGCTGTGATTTATGCAGCTTTGTTTCATTACATGCAAGTAGACAACATTTGTACTTGATAAAAATAATGCACTTTGAAATTACATTGATTTTTTGGAAGAGAGCAAGATAGTAGCTTCCAGAACCGTCCGGTGGCGGACCGAACTATTTTTGGGAAACACCAACTTTTTCCGTTTCTCTCTCTTCCGTGTTGCGATAACAATATCTGACACTCGAAATACACAAAAAAGTTCCCCTTGCGTAGTGAATATTTATGTCAGCAGTACATTAAGAGCTCTTGTATGTGAACGGACACCCCTCCGGTCTGTGTAAATGGAATATGACCGGGCGCATATATGGTCCTCGTGCTCCTCCTGTCTGGTTTGTGTTTCTCGGGCGGCGCCTTTCACATCTCTGAGGAGTGACGTTCACGACCGTCTGCAACCATGGAGTGGAAACCGATGGAAATAAACCCAGAGATGCTGAATAAGGTGTTGAGCAAGCTGGGTGTGGGCTCGAAATGGCGTTTTGTCGATGTTTTGGGTCTAGAAGATGAATCTTTGTCAGGAGTGCCCTCACCCTGCTGTGCCATGATGCTGCTCTTCCCTTTAACGCAACAGcatgAGGATTTCCGTTCTAAACAATCTGTTGGTGACTGTAAAGATGTGTATTTTCTGAAACAAACTGTGGTCAACTCCTGTGGAACTGTGGGCTTGGTTCATGCTGTGGCCAACAACCAGGACAGTATTGATTTTGATAATAATTCTGCACTAAAGAAGTTTCTAGAAGCCACCTCAGGGATGTCTCCTGCAGAACGAGCCAAAGAACTTGAACAAAATAAGGCTATCCAAGAAACTCATGATGCTGTTGCTGATGAGGGTCAGTGTCGGCCAGAGGCAGACAAAGTCAATTTCCATTTTATTACATTTGTCAATGTAAACGGTCGCCTTTATGAGCTGGATGGTAGAATTGATGGACCTGTGAGTCATGGGCCTACAAAACCAGACAGCTTTGTCATgGATGCGGCAAGGGTGTGCCGTGAGTTTATGGAGCGAGAGAAAGGGGAGGTGCGTTTCTCTGCTGTTGCTCTCTGCAAAGCCTGAGAGGAGCCAGACATCCGAGCTCAAACTACTGTACGAACAATTCCACAAAACCCTTCAACCACTTCTATACAGAGCACACAAACAATCCTTAACCATGCCTTGAAACATGCTACACAaactgcctgcctgcctgtctttCAGACTGTGAATCGCTGTcattttctaatttattatttatttaatttaaaagtttgTATAAATTCACCACTATTCTAATGTCTAAACTTTATTTTAGATTGATGTACCACTTCTAGTTCTAATTTCTTTGGGCACTTATTTTTTTGGAGGGGCTAATGTTTAGcagaaatgtaatgtaaaatttaAGCTTGAAGGTGCAAGTATGTGCAAAATAAAGACAGAAGGGTGATCTCA
>TCONS_00001938
TTGTGTTTCTCGGGCGGCGCCTTTCACATCTCTGAGGAGTGACGTTCACGACCGTCTGCAACCATGGAGTGGAAACCGATGGAAATAAACCCAGAGATGCTGAATAAGGTACGTTCGCTGAGTCATATGTGATGATGGAAGACTGGCTGTCTGTAGAGGACTGTGGCGTTCGTGGCTACACTGTTTTGGCCCTAAATCTAAACCGAAAGGGCGTGGACTTATACACATCGTCACCATAACACGTATCATGCAtggttaataaataaaagtgtccGTGCATAATCCCTCTATTCAGATGTATCGCTTATCTATAGTTGTTAATAATACACAGGCGAAAA

Function

symbol description
uchl1 Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. Predicted to act upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm. Is expressed in nervous system; neural tube; and trigeminal placode. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and hereditary spastic paraplegia. Orthologous to human UCHL1 (ubiquitin C-terminal hydrolase L1).

GO:

id name namespace
GO:0016579 protein deubiquitination biological_process
GO:0006508 proteolysis biological_process
GO:0006511 ubiquitin-dependent protein catabolic process biological_process
GO:0005737 cytoplasm cellular_component
GO:0004843 thiol-dependent ubiquitin-specific protease activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008234 cysteine-type peptidase activity molecular_function
GO:0016874 ligase activity molecular_function

KEGG:

id description
ko05012 Parkinson disease
ko05022 Pathways of neurodegeneration - multiple diseases
ko01002 Peptidases and inhibitors
ko04121 Ubiquitin system

ZFIN:

id description
ZDB-GENE-030131-3844 Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. Predicted to act upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm. Is expressed in nervous system; neural tube; and trigeminal placode. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and hereditary spastic paraplegia. Orthologous to human UCHL1 (ubiquitin C-terminal hydrolase L1).

Ensembl:

ensembl_id ENSDARG00000026871

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001937 False 1490 mRNA 0.42 9 22647756 22652424
TCONS_00001938 True 338 lncRNA 0.45 2 22651579 22652026

Neighbor

gene id symbol gene type direction distance location
XLOC_001209 chrnb5a coding downstream 53418 22542457 ~ 22594338 (-)
XLOC_001208 chrna6 coding downstream 135620 22481723 ~ 22512136 (-)
XLOC_001207 chrnb3a coding downstream 235714 22388799 ~ 22412042 (-)
XLOC_001206 si:ch73-380n15.2 coding downstream 277096 22236489 ~ 22370660 (-)
XLOC_001205 CR388092.1 coding downstream 455689 22191952 ~ 22192067 (-)
XLOC_001211 FP245458.1 coding upstream 11299 22663723 ~ 22674613 (-)
XLOC_001212 fgfbp1b coding upstream 25005 22677429 ~ 22678471 (-)
XLOC_001213 fgfbp2b coding upstream 33537 22685961 ~ 22691182 (-)
XLOC_001214 prom1b coding upstream 60507 22712931 ~ 22757145 (-)
XLOC_001215 tapt1b coding upstream 117831 22770255 ~ 22803147 (-)
XLOC_001204 NA non-coding downstream 646706 21999781 ~ 22001050 (-)
XLOC_001199 CR786570.1 non-coding downstream 967278 21680364 ~ 21680478 (-)
XLOC_001189 BX323083.5 non-coding downstream 1631826 21010689 ~ 21015930 (-)
XLOC_001188 BX323083.2 non-coding downstream 1641823 21000784 ~ 21005933 (-)
XLOC_001224 NA non-coding upstream 764491 23416915 ~ 23436608 (-)
XLOC_001225 NA non-coding upstream 793061 23445485 ~ 23447300 (-)
XLOC_001229 NA non-coding upstream 1099529 23751953 ~ 23783769 (-)
XLOC_001230 NA non-coding upstream 1256293 23908717 ~ 23911006 (-)

Expression


Co-expression Network