Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_016367 |
| gene name | tgfbr1a |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007113.7 |
| NCBI id | CM002886.2 |
| chromosome length | 59640629 |
| location | 23856045 ~ 23931536 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| tgfbr1a | Predicted to enable SMAD binding activity; activin binding activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in several processes, including heart development; protein phosphorylation; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to act upstream of or within phosphorylation and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane. Is expressed in brain; endoderm; eye; heart; and pharyngeal arch. Human ortholog(s) of this gene implicated in Ferguson-Smith tumor; Loeys-Dietz syndrome 1; Lynch syndrome; and urinary bladder cancer. Orthologous to human TGFBR1 (transforming growth factor beta receptor 1). |
| id | name | namespace |
|---|---|---|
| GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | biological_process |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | biological_process |
| GO:0007507 | heart development | biological_process |
| GO:0032924 | activin receptor signaling pathway | biological_process |
| GO:0071363 | cellular response to growth factor stimulus | biological_process |
| GO:0006468 | protein phosphorylation | biological_process |
| GO:0007399 | nervous system development | biological_process |
| GO:0016310 | phosphorylation | biological_process |
| GO:0048179 | activin receptor complex | cellular_component |
| GO:0005886 | plasma membrane | cellular_component |
| GO:0016020 | membrane | cellular_component |
| GO:0016021 | integral component of membrane | cellular_component |
| GO:0043235 | receptor complex | cellular_component |
| GO:0016361 | activin receptor activity, type I | molecular_function |
| GO:0048185 | activin binding | molecular_function |
| GO:0016740 | transferase activity | molecular_function |
| GO:0005524 | ATP binding | molecular_function |
| GO:0046332 | SMAD binding | molecular_function |
| GO:0000166 | nucleotide binding | molecular_function |
| GO:0004672 | protein kinase activity | molecular_function |
| GO:0004674 | protein serine/threonine kinase activity | molecular_function |
| GO:0004675 | transmembrane receptor protein serine/threonine kinase activity | molecular_function |
| GO:0016301 | kinase activity | molecular_function |
| GO:0005025 | transforming growth factor beta receptor activity, type I | molecular_function |
| id | description |
|---|---|
| ZDB-GENE-051120-75 | Predicted to enable SMAD binding activity; activin binding activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in several processes, including heart development; protein phosphorylation; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to act upstream of or within phosphorylation and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane. Is expressed in brain; endoderm; eye; heart; and pharyngeal arch. Human ortholog(s) of this gene implicated in Ferguson-Smith tumor; Loeys-Dietz syndrome 1; Lynch syndrome; and urinary bladder cancer. Orthologous to human TGFBR1 (transforming growth factor beta receptor 1). |
| ensembl_id | ENSDARG00000017494 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00032226 | True | 1703 | mRNA | 0.51 | 9 | 23856045 | 23931536 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_016366 | si:dkey-24c2.7 | coding | downstream | 72006 | 23773078 ~ 23784039 (-) |
| XLOC_016365 | xirp1 | coding | downstream | 87213 | 23749614 ~ 23768832 (-) |
| XLOC_016364 | cdyl | coding | downstream | 178623 | 23622788 ~ 23677422 (-) |
| XLOC_016363 | si:dkey-58b18.8 | coding | downstream | 246963 | 23604654 ~ 23609082 (-) |
| XLOC_016362 | si:dkey-58b18.9 | coding | downstream | 252984 | 23602463 ~ 23603061 (-) |
| XLOC_016368 | col15a1b | coding | upstream | 5418 | 23936954 ~ 24022085 (-) |
| XLOC_016369 | NA | coding | upstream | 95033 | 24026569 ~ 24069434 (-) |
| XLOC_016370 | CR788285.1 | coding | upstream | 144477 | 24076013 ~ 24105475 (-) |
| XLOC_016371 | myh7 | coding | upstream | 321451 | 24252987 ~ 24270062 (-) |
| XLOC_016372 | dre-mir-736 | coding | upstream | 329681 | 24261217 ~ 24261296 (-) |
| XLOC_016351 | NA | non-coding | downstream | 412856 | 23406472 ~ 23443189 (-) |
| XLOC_016347 | BX548024.1 | non-coding | downstream | 768721 | 23084639 ~ 23087324 (-) |
| XLOC_016346 | NA | non-coding | downstream | 828983 | 23025245 ~ 23027062 (-) |
| XLOC_016343 | BX649390.1 | non-coding | downstream | 958644 | 22897285 ~ 22897401 (-) |
| XLOC_016341 | NA | non-coding | downstream | 987325 | 22857105 ~ 22868720 (-) |
| XLOC_016374 | NA | non-coding | upstream | 379099 | 24310635 ~ 24317436 (-) |
| XLOC_016381 | BX530024.2 | non-coding | upstream | 574439 | 24505975 ~ 24506090 (-) |
| species | gene id | symbol | gene type | chromosome | NCBI id | location |
|---|---|---|---|---|---|---|
| grasscarp (Ctenopharyngodon idella) | CI01000004_07388945_07408147 | TGFR1, TGFBR1, TGFBR1A, TGFBR1B | coding | CI01000004 | null | 7388461 ~ 7408147 (-) |
