XLOC_017880 (cyp46a1.3)


Basic Information

Item Value
gene id XLOC_017880
gene name cyp46a1.3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 5272655 ~ 5291012 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035295
ATGACATCGGAGTGGCTCTTGTATATGGTGTTTTACCTTCTTTCTGCTGTTTTCGTTGTATTTCTTGCATACTGTCTGTATATTCATCAAGTTCAccagaaatatgatcatataccTGGACCTCCTAGAGACAATTTTCTGCTGGGACATATTCCAACTATTAACAGAGTGACAAAGTCGGAAAGACATATGAACGACTTATTACTTATATGGGCGGAAAAATATGGCCCTGTCTACAGGCTGAACAGTTTTCATTATGTCATAATCAATGTCCATTGCCCCGAGGCTACAAAGACAATCATGATGTCACCAAAGTATCTCAAAGATCCCTTTATCTACAAACGTCTCTTTGGCTTGTTTGGAAAAAGGTTCTTGGGGTATGGCCTGGTGACAGCCACAGACCATGACATCTGGTACAGGCAGCGTCGAATCATGGATCCAGCCTTCAGCAGCTCATACTTGCGAGGCTTGATAAGCACTTTTAATGAGATGTCAGAACGCCTGATGGACAAGCTGGAGGAAATGGCCATCAACAAAACCCCTGCCGTCATGCACGACCTGGTCAACTGTGTTACACTTGATATCATTTGCAAGGTCGCTTTCGGTGTTGATTTGAACTTGTTTAAGCAAACAGACAACCCTTTCCAGCAGGCAATAGAGCAGTGTTTACAGGGTATGGTGTTAGATCTAAGAGACCCATTTTGTAAGTTTTTTCCCAAGAATTGGAAGGCTATACAGGAAACTAAAGGTGCTACTGTACTCTTACGTAAAACGGGAGAGCAATGGATACAAAACAGAAAGACAGCAGTGGAAATTGGAGAGGACGTCCCCAATGACATTCTCACACAAATCCTCAAAACTGCAAAGGAGGAGAAAGTTAATAACACTAAAGATCATGAGCAGATGTTGGACAATTTTGTGACTTTCTTCATTGCTGGGCAAgagacaacagccaatcagctcTCGTTTGCAATCATGGAATTAGGGAGACATCCTGAGATATATAAACGAGCTAAAGCAGAGGTGGATGAAGTTCTTGGAACCAAAAGAGACATTTCATATGAAGACCTTGGAAAATTCACTTATTTGTCTCAGGTGTTGAAGGAAACCCTGCGTCTGTACCCGACTGCGCCAGGAACCAATCGCTGGCTTCATGAGGACATGGTCATAAACGGCATTAAAATCCCTGGAGGCATTTCTGTTATTTTCAGCTCTTATGTCGCCCAGAGACTGGAAAAGCATTTCAAAGATCCGTTGAAGTTTGATCCAGAGAGGTTTAATGTGAATGCGCCAAAGCCTTACTACTGCTACTACCCATTTTCACTTGGTCCAAGATCCTGTCTGGGGCAGGTCTTCTCACAGGCCACGCCAGCAGAGGGAGCCCTCGCCCAACTACTGACTCAGCTCCTCACCCTCTGCAGTCACTTCCTTATTGTGCTGTATTTTAGCAAGAGCTCAGGCCATGCTTCCTTGTGA

Function

symbol description
cyp46a1.3 Predicted to enable cholesterol 24-hydroxylase activity and heme binding activity. Predicted to be involved in cholesterol catabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CYP46A1 (cytochrome P450 family 46 subfamily A member 1).

GO:

id name namespace
GO:0006707 cholesterol catabolic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0004497 monooxygenase activity molecular_function
GO:0005506 iron ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0033781 cholesterol 24-hydroxylase activity molecular_function
GO:0020037 heme binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060519-40 Predicted to enable cholesterol 24-hydroxylase activity and heme binding activity. Predicted to be involved in cholesterol catabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CYP46A1 (cytochrome P450 family 46 subfamily A member 1).

Ensembl:

ensembl_id ENSDARG00000089177

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035295 True 1476 mRNA 0.44 15 5272655 5291012

Neighbor

gene id symbol gene type direction distance location
XLOC_017879 cyp46a1.4 coding downstream 5055 5256275 ~ 5267600 (-)
XLOC_017878 cyp46a1.2 coding downstream 18045 5237286 ~ 5254610 (-)
XLOC_017877 ccdc85cb coding downstream 43498 5158419 ~ 5229157 (-)
XLOC_017876 NA coding downstream 202465 5068812 ~ 5070190 (-)
XLOC_017874 arid1b coding downstream 219817 4897996 ~ 5052838 (-)
XLOC_017881 ism2b coding upstream 11174 5302186 ~ 5328637 (-)
XLOC_017882 CABZ01045949.1 coding upstream 30203 5321215 ~ 5321329 (-)
XLOC_017883 sptlc2b coding upstream 39528 5330540 ~ 5369105 (-)
XLOC_017884 snw1 coding upstream 87829 5378841 ~ 5400395 (-)
XLOC_017885 BX088548.1 coding upstream 322867 5613879 ~ 5613996 (-)
XLOC_017928 CU539064.1 misc upstream 4762393 10053405 ~ 10053701 (-)
XLOC_017875 BX649499.1 non-coding downstream 365178 4906078 ~ 4907477 (-)
XLOC_017869 NA non-coding downstream 776513 4495141 ~ 4496142 (-)
XLOC_017867 NA non-coding downstream 886348 4381929 ~ 4386307 (-)
XLOC_017865 NA non-coding downstream 1126523 4135534 ~ 4146132 (-)
XLOC_017886 CABZ01064253.1 non-coding upstream 704577 5995589 ~ 5995703 (-)
XLOC_017887 CABZ01062797.1 non-coding upstream 721439 6012451 ~ 6023109 (-)
XLOC_017888 CABZ01062796.1 non-coding upstream 737189 6028201 ~ 6035070 (-)

Expression


Co-expression Network