XLOC_017879 (cyp46a1.4)


Basic Information

Item Value
gene id XLOC_017879
gene name cyp46a1.4
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 5256275 ~ 5267600 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035294
TTCGATAGTAGTTATAGGCAGTGTGCAGACGTTTACAGTACAAAGCCATCATGATCTTAGAATGGAtcttatatataattttttacctGCTCTCTGCTGTTTTTACTGCATTTCTTGCGTATTGTCTGTACATTCATTATGTACAtcagaaatatgatcatataccTGGACCTCCAAGAGACAATTTTCTGTTCGGACATTCACCATCTCTTACTAAATCGATGTATGCCGACGACAGCCTTATACATGACTTGTTTCTTCAATGGGCAGAAAAATATGGCCCAGTTTACAGAATCAACAGTTTGCATTATATCGCAATAGTGGTTCACTGCCCTGAGGCTACGAAGACAATCTTGATGTCACCCAAGTATACCAAGGATCCATTTGTCTACAGACGCCTATTTAACTTGTTTGGGAAAAGGTTCTTGGGATATGGGCTAATTACAGCTGTGGACCATGACATCTGGTACAGGCAGCGTCGCATCATGGATCCAGCCTTCAGCAGCTCATACTTACGAAGCTTGATAAGCACTTTTGACGAGATGTCAGAACGCCTGATGGACAAGCTGGAGGAAATGGCCAACAACAAAACCCCTGCCGTCATGCACGACCTGGTCAACTGTGTTACACTTGATGTCATTTGCAAGGTGGCTTTTGGTGTTGATTTAAACTTCTTGGCGCAAAAGGATAGTCCCTTCCAGAACGCAGTAGAGCTTTGTTTAAATGGCATGACCGTAGATCTCAGGGACCCATTTTTTAGGCTTTTTCCCAAAAATTGGAAGCTTATACACCAAATCAGAGATGCAGCTGAACTCTTGCGTAAAACGGGagagaaatggatacaaaacAGGAAGACAGCAGTGAAAAATGGAGAGGACGTCCCCAAAGACATTCTCACACAAATCCTCAAATCAGCAGAGGAAGAAAATGTTAATAACACAGATGATCTTGAGCAGATGTTGGACAATTTTGTGACTTTCTTTATAGCTGGCCAAgagacaacagccaatcagctcTCATTTGCAATCATGGCATTAGGGAGAAATCCAGAGATATACAAGCGAGCTAAAGCAGAGGTGGATGAAGTCCTCGGAACCAAAAGAGAAATTTCAAATGAAGACCTTGGAAAGTTTACTTACTTGTCTCAGGTGTTAAAGGAAACCCTGCGTCTGTACCCCACTGCGCCAGGAACCAATCGCTGGCTTCATGAGGACATGGTCATAAACGGCATTAAAATCCCTGGAGGCTGTTCTGTTATGTTCAGCTCGTATGTCTCCCAAAGACTGGAAAAGTTTTTCAAAGATCCGTTGAAGTTTGATCCAGAGAGGTTTGATGTGAATGCCCCAAAGCCTTATTACTGCTACTTCCCATTTGCACTTGGTCCACGAACCTGTCTAGGGCAGGTCTTCTCACAGATGGAGGCAAAAGTTGTGCTTGCCAAACTGCTCCAGAGATTTGAGTTCAGTCTGGTCCCTGGACAGTCTTTCGACATTAAAGACACGGGAACTCTACGGCCCAAGAGCGGAGTGATCTGCAACATCAAGCAGTGCTCATAGGACATGTTTAAATCTCTAATGACAGCTCTTCTGAAATAAATCCTCTTATATTAGCCAAACATTAATCAGAGAACAGAAGTTGAGCAATCACCGATTATGATCCATCAATTGATTACAATGAAAATACATTAACTCACagtacattaattaatattaagtGTGCTTCACAGTATTCACTGCATTAAATGTGCTTCACACTGGTGAGTGgtctgacaaaccacctgtagaaacataTCATCTCTTTCTcattaatcaaaacaataaacattCCCACTCCTTACTCTAGC

Function

symbol description
cyp46a1.4 Predicted to enable cholesterol 24-hydroxylase activity and heme binding activity. Predicted to be involved in cholesterol catabolic process. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CYP46A1 (cytochrome P450 family 46 subfamily A member 1).

GO:

id name namespace
GO:0006707 cholesterol catabolic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0005506 iron ion binding molecular_function
GO:0033781 cholesterol 24-hydroxylase activity molecular_function
GO:0020037 heme binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1224 Predicted to enable cholesterol 24-hydroxylase activity and heme binding activity. Predicted to be involved in cholesterol catabolic process. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CYP46A1 (cytochrome P450 family 46 subfamily A member 1).

Ensembl:

ensembl_id ENSDARG00000113820

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035294 True 1843 mRNA 0.42 15 5256275 5267600

Neighbor

gene id symbol gene type direction distance location
XLOC_017878 cyp46a1.2 coding downstream 1665 5237286 ~ 5254610 (-)
XLOC_017877 ccdc85cb coding downstream 27118 5158419 ~ 5229157 (-)
XLOC_017876 NA coding downstream 186085 5068812 ~ 5070190 (-)
XLOC_017874 arid1b coding downstream 203437 4897996 ~ 5052838 (-)
XLOC_017875 BX649499.1 coding downstream 348798 4906078 ~ 4907477 (-)
XLOC_017880 cyp46a1.3 coding upstream 5055 5272655 ~ 5291012 (-)
XLOC_017881 ism2b coding upstream 34586 5302186 ~ 5328637 (-)
XLOC_017882 CABZ01045949.1 coding upstream 53615 5321215 ~ 5321329 (-)
XLOC_017883 sptlc2b coding upstream 62940 5330540 ~ 5369105 (-)
XLOC_017884 snw1 coding upstream 111241 5378841 ~ 5400395 (-)
XLOC_017928 CU539064.1 misc upstream 4785805 10053405 ~ 10053701 (-)
XLOC_017869 NA non-coding downstream 760133 4495141 ~ 4496142 (-)
XLOC_017867 NA non-coding downstream 869968 4381929 ~ 4386307 (-)
XLOC_017865 NA non-coding downstream 1110143 4135534 ~ 4146132 (-)
XLOC_017885 BX088548.1 non-coding upstream 346279 5613879 ~ 5613996 (-)
XLOC_017886 CABZ01064253.1 non-coding upstream 727989 5995589 ~ 5995703 (-)
XLOC_017887 CABZ01062797.1 non-coding upstream 744851 6012451 ~ 6023109 (-)
XLOC_017888 CABZ01062796.1 non-coding upstream 760601 6028201 ~ 6035070 (-)

Expression


Co-expression Network