XLOC_022505 (itga5)


Basic Information

Item Value
gene id XLOC_022505
gene name itga5
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 33447625 ~ 33558161 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00044374
ATTAAGCTGGAGGGAGGACGCAGAAAGGAGAGGACGGGACAGATAGACGGAGGCGCGGTAACAGAGCGCTTGGAAAAATAAGGATCTGACTGATTCACTTCACCAAGGCATGAGATTTGCGTAAGGCAGCAGCTTCAGCAGGATTCCGCTTAAGTGCATCACTTTTCTTGTGAAAGAAGTTTAATAAAGCAGTGGATTTTGATACATCGGTTACTATGGGCTGCAAACGGCACCGTTCAAAGACTTCGGCGTCTACAAGCTGCTCTCCAATGGGACTTTCGTTGTTGATTCTTCTACCTTTGTCTGTTGCCTTCAACTTGGATGTGGAGAATCCAGCGGTGTATAACGGACCCAGCGGTAGCTACTTCGGGTACTCGGTGGACTTTTATATGACTGACTCAAGTGTGAGCATTATAGTTGGAGCACCCAAAGCCAACACCAGTCAGCCCAAGATCACAGAAGGAGGATCGGTCTTCTACTGTCCGTGGAgtctcagccaatcacaatgcagCAGCATAGAGTTCGATAGACTGGGAGATCTTAACATGTCCGTGAATGACACAGACCATCAAGGAGAGTTCAAATCCCATCAGTGGTTTGGAGCAACAGTACGAGTGCATCAAGACAGTGTGCTGGCTTGTGCTCCTCTTTACTCGTGGAGAACCAAGGAGGACACTCCTCATGCTGATACGACTGGCTCTTGTTTTATGTCTGTCAAAAACTTCACCAAGTTTGTGGAATATGCTCCGTGCCGCACAGAATTTCGTGGAAGGAAAGGGCAAGGCTACTGTCAAGGTGGATTCAGTGCTGATTTTACTCAGGAAGGAAAGGTGGTGCTGGGAGGACCTGGCAGTTACTTCTGGCAAGGCCAAGTAATCACTGCGTTCAAACAAGAAATTGTCAAAGCCTATTACCCAGGATACTTCTTGACCTCAGTGGGTGGCCAGATCCAGACCAAACAGAGAAAAGAGATCAGATTTGATGACACCTACATGGGTTATTCAGTGGCTGTGGGCGAGTTTACcggtgatgatgatgaagACTTTGTGACTGGAGTTCCCAGGGGAGTCAGACTGCATGGACAGgTTTCCATTCTCAATAGCTCTCTGGATGTGCTGAAGATGTTCACTGGTGAACAGATGGGGTCTTACTACGGCTATTCTGTGGCTGCCACTGACATTAACAATGACGGAATGATGGACCTGCTGGTTGGCGCTCCCATGTTCATGGTTCGTGACTCTGATGGGAGGTTGGAGGAGTTGGGTCGAGTTTATGTGTATATGCAAAAAGGTCCTCTGGATCTCATTCCTCAGCTACCTCACCTCACCGGCACACAAATGTTTGCCCGATTTGGGAGCTCCATTACACCACTTGGAGACCTCAACCAAGATGGATACAATGATGTGGCCATCAGCAGTCCATTTGGTGGTGAAGACAAGCAAGGGCTGGTGCTCATATATAATGGGAATGCTGGAGGACTCAGGGAAAAGCCCTCTCAGGTGATCTCTGGACAATGGGCTTCTGCCGGACTGTCAGCGATACCTGCTAGTTTTGGTTATGCACTTCGCGGAGGCAAAGACCTAGATAACAATGGCTACCCAGATCTCATTGTTGGGGCATTTGGTGCAGACAAAGCTGTTCTTTACAGGTCCCGTCCTATTGTGAACACCAGTGCCATCTTAAATGTCTACCCTATTATGATCAATCCTGAGGAGAAAGTCTGCGCCATAAGCCGTGGGAATGAGACGCTGCATGTGTCCTGTGTCAACTTAAGCTTCTGCCTTTCAGCCAATGGCAAGCACCTGCCAAATCATCTCGagtTTAATGTGGAAGTTCAGCTGGACCGTCTGAAGCAACAGCAGAAAGGGGCCGTACGGAGAGCTCTGTTTTTAGAAACACAGCTCCCTGCTTTGCATCGGACGCTGACTGTGCCGAATGGAGCCAGAGTCTGCAGCGATACCAAGATCTACCTGCGGGATGAGAAGGACTTCAGGGATAAACTGTCTCCCATCTTCGTTGCTCTGAACTTCAGCCTGAATCCTCAAGCAGCAGCAGACAGGCACGGACTGCAGCCCATCCTCAACTACCAGACGGCAGAGCTCATTGAACAGAAAGCCCAGATTTTATTGGACTGCGGAGAGGACAACATCTGCGTCCCTGACCTGAAACTCTCTGTGCACGGGGACAGGAAGGAAGTGTACATGGGTGACGACAACTCTCTAACCCTGACTTTCAATGCGAAAAACGACGGAGGCGGCGCTTACGAGGCAGAGCTGTATGTGGTCCTACCACCAGAGGCCGACTACAGCGGAATAGCCCGAAATAATGAGAGCCTGACCCAGCTGACCTGCAGTTACGAGACGGAAAATCAGACCCGTTACCTCAGCTGTGACCTGGGGAACCCCATGAAGTCGGGCACCAGCctaTGGGCTGGTCTGCGGTTCACAGTACCACGTCTCAAGGACACACACAATTTTGTACAGTTTGACCTTCAGATTCGTAGCAAGAATGAGAACAACTCTCAAAGTGAAGTGGTCCCTTATAAGCTGGAGGTGGTGGTTCGCTCTGATGTCATTCTGCAGGGCGTCTCCCGACCAGACAAGGTCTTCTTTCCCCCTCCCAACTGGAAGCTGACCAAGAATGTGATGGTTGAACAGAATGTGGGTCCCTCCGTCCAGCACACTTACGAGctGGTGAACAATGGGCCGAGTCGCATCAGTCACACTTTACTGCAGCTCAAATGCCCCATGAGGCTTCACAGTAACCGGTTCATTTACCCGCTGGAGGTCACCACGGAGGGCCCGGTTAACTGCACCACCCACAACATCATCAACCCACTCAACCTGAAGCTGCAGCAGTCTTCAACAGAGCAGCCTCCTGTACGAGATTCAGGGCACGAACACCACATTGAGAAGCGGGACACGCACAAGGGAGAGCTCTCGCAACTGACCAATCTGTCTTGCTCCAGTGTGGACTGTTGGACTCTGATGTGTAATGTTGGCCTGTTGGAGCGAGGGACGAGTGCCATACTTCATGTTCGCTCACGAATTTGGGCTGAAACGTTTATGGAGAACACTTATAAAAACTTTATTCTGGAGTGCCATGCTAGTTACAAAGTGGAAAAGATGCCATATGCCATTTTGCCTAAGGTGACTCCTAGTGGCTCTAAAAAGATGGTGACTCCTGTGGTGTGGAATAAGCCGGACAGTTCGTACGCTGTTCCTCTGTGGATCATCATTCTGGCGATTCTAGCTGGTCTTCTGCTGCTCGCGCTGCTCATCTACGTCCTCTACAAGCTCGGCTTCTTCAAGCGAACTCCATACGGCACTGCGATGGAAAAAGCCCAACTCAAACCTCAGGCTGCATCCGAGGCCTAAACGAAGAGATGGTTCACGTCCTTAACCAAAGGCCGTCCAAAGAGAAGCTGACTTGCTGTTGAAAAGACAAAGACTAGACTGCAGTAGAGTAGACGGCGGAGGAAAGATCACTGGATCTTCACTGTACTGCACTAGATAACGAGACCCTGAGGACTTAAAGCCAAATGAATGTtgactttgtttattttaactcGTTTTTTCCCCTTGATGTGGGTTTCCACTTTTAACCACCACTTACAGCCTGCCGCTCACAAACAGTTTTGGGTTGATCTGAACCAAAGCTCAGGATCACTGGCAACCTGctaaagcagaaaaaaaacaaaaaaaaaaacggattcAGCCCAAGTTGGACTCAATCTGCACTAATGTAATTatgttcgattttttttttttaacaatttcatgtcttttttttttttagcccacAGCTGCTCAAGGTTAAACAATCCGCAGTGTAGCATTTTCTATTTTTAGCATGCTATCTCACTAAAACACACCCTCAAAGAACATCTATGCAGTATTTCACATCCAACCAAAGTTAATGATACAGGTTTTGCTGATTTATTGTGTCTTGCAAGCGAGAATGAGGTAGTCGGATACCTCACCAGGGACCCTCATCTCCATTTTCCTGCTGTCTATTTTGTTTATGaagacattttaaatgtttgtttgtcaCGTGACTTCTAATGGATAGAGTTTTCACTCTGAACGAGATGTTTTCAGCTCAGTCGCCTCATAGCAAGCCAAGTTTCACTCTCAGGTGATGCCGCGTAAAGGATCAAGTGGCGCTCTTTCAGTGGAAAACATTGTCAGGATCCTTTGCGGAAGGCGACCGTTCTTCCCTACTGAATGTTAGCCGTTTGCCTTAAAAGTCATCTGGGACAAAACTGGATCCGAGTCTGTGAAACCTCACCGATGCCTTGAAGCAGAGCTGTGCTTTGCCATTACGCTAACAGACCCTCGGGCCAAAAGAGCAAAAACAATGTCATCACTCCAAACTTCTGTGGGCAAACGGAGACCCACTGTAGACTTGGATGGAGATTTACACAAAAACTCTTCCAAGGCAGCAGGCCTCATCCAGGGACTGAATGTTGAAATACACCTGTATACTTCTTGTCTTTTGTATGCGTGTTTGTGTTCTGCTTGTGTGTAtggatgtgatttttttttttttcttggagtgCCACAGTCAGTAGAAATGCCTCCATACATCATGGTGCTGAAGTGGTTGAGTGCGGGAATGAAATGAAAACTCCTGTTTCAGCGAGCTGCCTAGAAGGCGACAGCAGCTGGAACCGTGGGATGCGTAGGAAATCTGTATGGAAGTGCAATATTCAACTTTTTCTATGTGcataataatactttattttagtGTCGCTCTCAGAAATAAGGATTATTTGAAGACAACACCCAGTTTGAGGGTTGAAATTAGCCCAGATTTAAGGTAATTAATGTAATGCTGTAGGCTAAAACATACAGAAACACGGCTTCATCTGTCAAAGaagaattatttttaatggttaaGTGTGATAATGCCATAAAAtagacattttagacatttttttgtCTGCCATATTGTAAATGCAGGTTTTACCAAACAAATGGGGTAGTTTGAATTGGTACACAACCAAAGAAGCTGACACACAGACTCGACTTGAATCCTtagtaatgtttttaatgtattttgtacatttttacaaacaaatatttattccTCCAAAGTTAGATTTTagtcttgagattttttttgttgtattttaaacAGGAGGAAACACTGGGtatgtcttctttttttgtttattttcttttgctttttttttttaccagcccCAAATcttggtttgtgtttttttttttttgcattgagttgtaaatatgtttggtgaggagattattttaatttttcagcTGATACTGATTTGACGTATTTCATCACCCCATATTGGGGAGAATCAGAGGGATGTTCAagtaattattatttgtatttacagtttgctttttaaaataaatctttcatTTTTTTGTACA
>TCONS_00044375
aaatatagatttttttcatttttgcagaCGTTGAAAGGCCCCACAGAAATCCTGCTTTTGATAGTGCAGCTCAACATGACCTCACTCAGATGAATGGGAGAGGATGCGTTTGCATGTTTCCACTTGTGTTTTTTGGATGGAATACAGGAAAGAAATGTTCCACCATCCAGTAGATTCATTCTGTTGCCATGGCAGAGCATTATGGGGGATTCCTTTACTTTGTTTGCTGTGGAGAACTGTATTGTGACATTGAAAATAGTGTTGGACCATTTATGATAAATCAATTAATATGTACTTAATGTGCTTTTCAGAAAAGTTTATTACTTAGAGTTAATGAGATTTTATTAAAAagagtattgttttattttcagctaTGGGCTGGTCTGCGGTTCACAGTACCACGTCTCAAGGACACACACAATTTTGTACAGTTTGACCTTCAGATTCGTAGCAAGAATGAGAACAACTCTCAAAGTGAAGTGGTCCCTTATAAGCTGGAGGTGGTGGTTCGCTCTGATGTCATTCTGCAGGGCGTCTCCCGACCAGACAAGGTCTTCTTTCCCCCTCCCAACTGGAAGCTGACCAAGAATGTGATGGTTGAACAGAATGTGGGTCCCTCCGTCCAGCACACTTACGAGctGGTGAACAATGGGCCGAGTCGCATCAGTCACACTTT

Function

symbol description
itga5 Enables fibronectin binding activity and protein heterodimerization activity. Acts upstream of or within several processes, including camera-type eye development; cell migration involved in sprouting angiogenesis; and chordate embryonic development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of integrin complex. Is expressed in several structures, including cardiovascular system; ectoderm; head; mesoderm; and somite. Orthologous to human ITGA5 (integrin subunit alpha 5).

GO:

id name namespace
GO:0021782 glial cell development biological_process
GO:0090245 axis elongation involved in somitogenesis biological_process
GO:0001756 somitogenesis biological_process
GO:0007229 integrin-mediated signaling pathway biological_process
GO:0002042 cell migration involved in sprouting angiogenesis biological_process
GO:0001501 skeletal system development biological_process
GO:0070309 lens fiber cell morphogenesis biological_process
GO:0002089 lens morphogenesis in camera-type eye biological_process
GO:0085029 extracellular matrix assembly biological_process
GO:0032525 somite rostral/caudal axis specification biological_process
GO:0030325 adrenal gland development biological_process
GO:0001944 vasculature development biological_process
GO:0060041 retina development in camera-type eye biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0007155 cell adhesion biological_process
GO:0008305 integrin complex cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0046982 protein heterodimerization activity molecular_function
GO:0001968 fibronectin binding molecular_function

KEGG:

id description
ko04151 PI3K-Akt signaling pathway
ko04512 ECM-receptor interaction
ko04145 Phagosome
ko04510 Focal adhesion
ko04810 Regulation of actin cytoskeleton
ko04640 Hematopoietic cell lineage
ko05206 MicroRNAs in cancer
ko05205 Proteoglycans in cancer
ko05168 Herpes simplex virus 1 infection
ko05165 Human papillomavirus infection
ko05131 Shigellosis
ko05135 Yersinia infection
ko05133 Pertussis
ko05100 Bacterial invasion of epithelial cells
ko05410 Hypertrophic cardiomyopathy
ko05412 Arrhythmogenic right ventricular cardiomyopathy
ko05414 Dilated cardiomyopathy
ko04147 Exosome
ko04515 Cell adhesion molecules
ko04090 CD molecules

ZFIN:

id description
ZDB-GENE-031116-52 Enables fibronectin binding activity and protein heterodimerization activity. Acts upstream of or within several processes, including camera-type eye development; cell migration involved in sprouting angiogenesis; and chordate embryonic development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of integrin complex. Is expressed in several structures, including cardiovascular system; ectoderm; head; mesoderm; and somite. Orthologous to human ITGA5 (integrin subunit alpha 5).

Ensembl:

ensembl_id ENSDARG00000006353

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00044374 False 5405 mRNA 0.46 30 33447625 33558161
TCONS_00044375 True 676 lncRNA 0.42 4 33463217 33468329

Neighbor

gene id symbol gene type direction distance location
XLOC_022504 NA coding downstream 5283 33406774 ~ 33442342 (-)
XLOC_022503 NA coding downstream 63761 33378523 ~ 33383864 (-)
XLOC_022502 slc48a1a coding downstream 86200 33357163 ~ 33361425 (-)
XLOC_022501 si:ch211-226m16.2 coding downstream 96635 33337734 ~ 33350990 (-)
XLOC_022499 NA coding downstream 110771 33232978 ~ 33336854 (-)
XLOC_022506 NA coding upstream 49848 33608009 ~ 33618846 (-)
XLOC_022507 csrnp2 coding upstream 75080 33633241 ~ 33680265 (-)
XLOC_022508 pou6f1 coding upstream 123516 33681677 ~ 33710029 (-)
XLOC_022509 NA coding upstream 173028 33731189 ~ 33739111 (-)
XLOC_022510 bin2a coding upstream 181054 33739215 ~ 33753361 (-)
XLOC_022500 AL929087.2 non-coding downstream 146206 33301304 ~ 33301419 (-)
XLOC_022498 AL929087.1 non-coding downstream 228497 33219005 ~ 33219128 (-)
XLOC_022513 CT025912.1 non-coding upstream 410705 33968866 ~ 33968988 (-)
XLOC_022515 NA non-coding upstream 1209160 34767321 ~ 34768151 (-)
XLOC_022518 NA non-coding upstream 1642531 35200692 ~ 35203084 (-)

Expression


Co-expression Network