XLOC_022866 (eif2s3)


Basic Information

Item Value
gene id XLOC_022866
gene name eif2s3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007135.7
NCBI id CM002908.2
chromosome length 42172926
location 16983269 ~ 17002950 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00045448
ATAACATAAGAACTACAAAACTTCTGACGTCATTATAATAAGACGGACCCTTGTTTCATCAGTATCAGCCCAACGTGTTTTCAAGTTTGCTGACGTTAATCACAATTAGATGGCGGGCGACGAGTCTGGAACAACGTTGGGTCAGCCCCATCTTTATAAACAAGATCTCAGTACACTAGATGTGAGCAAACTGACTCCTCTCTCCCAAGAGATCATCAGCAGACAAGCCACAATAAACATAgGAACTATTGGTCATGTAGCCCATGGAAAATCAACAGTGGTGAAAGCCATCTCTGGAGTTCACACTGTCAGATTCAAAAACGAGCTGGAGAGGAACATTACAATCAAGTTGGGCTATGCTAATGCCAAGGTGTATAAATTGGACGACCCAAGTTGTCCACGGCCGGAGTGTTACAGGTCTTGTGGCAGCAGCACACCTGATGAGTTCCCTACAGACATTCCTGGCACCAAAGGCAACTTCAAACTAGTCCGacATGTCTCATTTGTGGATTGCCCAGGTCACGACATCTTGATGGCCACCATGTTAAACGGTGCTGCTGTAATGGATGCTGCGCTGCTCCTAATCGcTGGCAATGAATCATGTCCTCAGCCTCAGACGTCAGAGCATTTGGCTGCCATTGAGATCATGAAGCTCAAGCACATACTGATTCTGCAGAATAAAATCGACTTGGTGAAAGAGAGTCAGGCCAAAGAGCAGTATGAACAGATCCTGGCGTTTGTGCAGGGTACAGTAGCAGAGGGAGCTCCAATTATCCCGATCTCAGCCCAGCTCAAGTACAACATCGAAGTTGTTTGCGAGTACATTGTAAATAAGATCCCCGTGCCTGTCCGCGACTTCACCTCTGAGCCTCGACTTATTGGTA
>TCONS_00045449
ATAATAAGACGGACCCTTGTTTCATCAGTATCAGCCCAACGTGTTTTCAAGTTTGCTGACGTTAATCACAATTAGGATGTGAGCAAACTGACTCCTCTCTCCCAAGAGATCATCAGCAGACAAGCCACAATAAACATAgGAACTATTGGTCATGTAGCCCATGGAAAATCAACAGTGGTGAAAGCCATCTCTGGAGTTCACACTGTCAGATTCAAAAACGAGCTGGAGAGGAACATTACAATCAAGTTGGGCTATGCTAATGCCAAGGTGTATA
>TCONS_00045450
AGTATCAGCCCAACGTGTTTTCAAGTTTGCTGACGTTAATCACAATTAGGTAAATCGTGATATTTGTATGTtgctgctttcattttatttgttaccCATAGTTTAGAATGCGATTTCCGGTCTATCTTCTCTTCTTGGGATTTCCTGTCCTTTTCTAGAATCGGATTGCATCATCCCATACGTTACCTCCTGGACGCCGTTAAATATATGAGTTTATAATTATTTGTCTCATTTAATGGTTTGATACAGTGTAATAGTAAGAATTACAACTTTATCTAACTTCATATGACCGAAACTGCGATGTAATTGCACAGAATATTATTTAATcgcatatatttatttgtaaaaaacgGTCAGGCGCTTGCGTGGTCATACCCTCATTCCTTTTCTTTCAAGATGGCGGGCGACGAGTCTGGAACAACGTTGGGTCAGCCCCATCTTTATAAACAAGATCTCAGTACACTAGATGTGAGCAAACTGACTCCTCTCTCCCAAGAGATCATCAGCAGACAAGCCACAATAAACATAgGAACTATTGGTCATGTAGCCCATGGAAAATCAACAGTGGTGAAAGCCATCTCTGGAGTTCACACTGTCAGATTCAAAAACGAGCTGGAGAGGAACATTACAATCAAGTTGGGCTATGCTAATGCCAAGGTGTATAAATTGGACGACCCAAGTTGTCCACGGCCGGAGTGTTACAGGTCTTGTGGCAGCAGCACACCTGATGAGTTCCCTACAGACATTCCTGGCACCAAAGGCAACTTCAAACTAGTCCGacATGTCTCATTTGTGGATTGCCCAGGTCACGACATCTTGATGGCCACCATGTTAAACGGTGCTGCTGTAATGGATGCTGCGCTGCTCCTAATCGcTGGCAATGAATCATGTCCTCAGCCTCAGACGTCAGAGCATTTGGCTGCCATTGAGATCATGAAGCTCAAGCACATACTGATTCTGCAGAATAAAATCGACTTGGTGAAAGAGAGTCAGGCCAAAGAGCAGTATGAACAGATCCTGGCGTTTGTGCAGGGTACAGTAGCAGAGGGAGCTCCAATTATCCCGATCTCAGCCCAGCTCAAGTACAACATCGAAGTTGTTTGCGAGTACATTGTAAATAAGATCCCCGTGCCTGTCCGCGACTTCACCTCTGAGCCTCGACTTATTGTAATCAGGTCGTTTGATGTCAATAAGCCTGGCTGTGAAGTAGATGATCTGAAAGGTGGTGTAGCTGGAGGAAGTATCCTCAAAGGTGTCCTGAAGGTCGGACAGGAGCTTGAGGTCAGACCAGGTATCGTTTCAAAGGACCATGAAGGGAAATTAATGTGCAAACCCATCTTCTCCAAAATCGTCTCACTTTTTGCCGAACACAATGACCTTCAGTATGCTGCTCCTGGTGGCCTTATTGGTGTTGGCACCAAGATTGACCCTACACTGTGCAGAGCGGATCGAATGGTGGGTCAGGTCCTCGGTGCAGTGGGGGCTCTTCCTGAGATCTTTACAGAGCTGGAGATCTCCTACTTCCTCTTGAGAAGACTGCTAGGTGTGCGCACTGAAGGGGACAAGAAAGCAGCCAAGGTTCAGAAGCTGTCGAAGAATGAGGTGCTGATGGTAAACATTGGCTCGCTGTCAACAGGAGGCCGTGTGAGTGCAGTCAAAGCTGATCTGGCTAAGATTGTGCTCACAAACCCTGTTTGCACAGAGGTGGGGGAGAAGATCGCCTTGAGTCGCAGAGTGGAGAAACATTGGCGtttgatcGGATGGGGGCAGATCAGGAGAGGTGTAACCATCACACCAACAGTCGACGATGATTGAGGAGTGACCACAACCTGTCAGTGGCTGGCACTGTCTCTCTACCGGACATAATTATTAAACCATTTTCACACACACTTGAGCACAGGCCAGCGCGTTTCGCCATCAGCGCAGAGTGAAGGGAAGAGCTCTTTTTGAGGGGAACGCACTGGCCCTGTATTTTAAGATGTTCGCCATACTCAGAGGAAAGATTGGTGTCATTTATATGAGAAATGCAATGAAAACATTATTCCTTGGCTTGGCGAAGAAATTGTCAACATCTTTCAGTGATgacaaataaaaaaccttttgGATCAAACC
>TCONS_00045451
CACACTGTCAGATTCAAAAACGAGCTGGAGAGGAACATTACAATCAAGTTGGGCTATGCTAATGCCAAGGTGTATAAATTGGACGACCCAAGTTGTCCACGGCCGGAGTGTTACAGGTCTTGTGGCAGCAGCACACCTGATGAGTTCCCTACAGACATTCCTGGCACCAAAGGCAACTTCAAACTAGTCCGacATGTCTCATTTGTGGATTGCCCAGGTCACGACATCTTGATGGCCACCATGTTAAACGGTGCTGCTGTAATGGATGCTGCGCTGCTCCTAATCGcTGGCAATGAATCATGTCCTCAGCCTCAGACGTCAGAGCATTTGGCTGCCATTGAGATCATGAAGCTCAAGCACATACTGATTCTGCAGAATAAAATCGACTTGGTGAAAGAGAGTCAGGCCAAAGAGCAGTATGAACAGATCCTGGCGTTTGTGCAGGGTGTTGGCACCAAGATTGACCCTACACTGTGCAGAGCGGATCGAATGGTGGGTCAGGTCCTCGGTGCAGTGGGGGCTCTTCCTGAGATCTTTACAGAGCTGGAGATCTCCTACTTCCTCTTGAGAAGACTGCTAGGTGTGCGCACTGAAGGGGACAAGAAAGCAGCCAAGGTTCAGAAGCTGTCGAAGAATGAGGTGCTGATGGTAAACATTGGCTCGCTGTCAACAGGAGGCCGTGTGAGTGCAGTCAAAGCTGATCTGGCTAAGATTGTGCTCACAAACCCTGTTTGCACAGAGGTGGGGGAGAAGATCGCCTTGAGTCGCAGAGTGGAGAAACATTGGCGtttgatcGGATGGGGGCAGATCAGGAGAGGTGTAACCATCACACCAACAGT

Function

symbol description
eif2s3 Predicted to enable translation initiation factor activity. Predicted to contribute to tRNA binding activity. Predicted to be involved in formation of translation preinitiation complex and positive regulation of translational fidelity. Predicted to act upstream of or within translational initiation. Predicted to be part of eukaryotic translation initiation factor 2 complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in MEHMO syndrome. Orthologous to several human genes including EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma).

GO:

id name namespace
GO:0001731 formation of translation preinitiation complex biological_process
GO:0006412 translation biological_process
GO:0006413 translational initiation biological_process
GO:0045903 positive regulation of translational fidelity biological_process
GO:0005829 cytosol cellular_component
GO:0005850 eukaryotic translation initiation factor 2 complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0000049 tRNA binding molecular_function
GO:0003924 GTPase activity molecular_function
GO:0005525 GTP binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0003743 translation initiation factor activity molecular_function

KEGG:

id description
ko03012 Translation factors

ZFIN:

id description
ZDB-GENE-030131-5552 Predicted to enable translation initiation factor activity. Predicted to contribute to tRNA binding activity. Predicted to be involved in formation of translation preinitiation complex and positive regulation of translational fidelity. Predicted to act upstream of or within translational initiation. Predicted to be part of eukaryotic translation initiation factor 2 complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in MEHMO syndrome. Orthologous to several human genes including EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma).

Ensembl:

ensembl_id ENSDARG00000008292

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00045448 False 884 mRNA 0.47 8 16983269 16992516
TCONS_00045449 False 274 processed_transcript 0.42 4 16983303 16985539
TCONS_00045450 False 2112 mRNA 0.46 12 16983329 17002950
TCONS_00045451 True 839 mRNA 0.51 7 16985181 17002640

Neighbor

gene id symbol gene type direction distance location
XLOC_022865 cct5 coding upstream 70372 16905188 ~ 16912897 (+)
XLOC_022863 NA coding upstream 81408 16719606 ~ 16901861 (+)
XLOC_022864 BX004771.1 coding upstream 175621 16807521 ~ 16807648 (+)
XLOC_022862 sema5a coding upstream 276288 16393302 ~ 16706981 (+)
XLOC_022861 BX005275.1 coding upstream 774269 16207562 ~ 16209000 (+)
XLOC_022867 zfx coding downstream 2697 17005647 ~ 17023677 (+)
XLOC_022868 pip4k2aa coding downstream 65774 17068724 ~ 17127833 (+)
XLOC_022869 mllt10 coding downstream 137988 17140938 ~ 17216312 (+)
XLOC_022870 commd3 coding downstream 253843 17256793 ~ 17259643 (+)
XLOC_022871 bmi1a coding downstream 257051 17260001 ~ 17267235 (+)
XLOC_022859 NA non-coding upstream 788539 16166765 ~ 16194730 (+)
XLOC_022860 BX005275.2 non-coding upstream 805969 16174199 ~ 16177300 (+)
XLOC_022873 NA non-coding downstream 277890 17280840 ~ 17282535 (+)
XLOC_022874 BX005392.4 non-coding downstream 315571 17318521 ~ 17319849 (+)
XLOC_022875 NA non-coding downstream 319536 17322486 ~ 17325645 (+)
XLOC_022876 NA non-coding downstream 329216 17332166 ~ 17334612 (+)
XLOC_022879 CU041377.1 non-coding downstream 735569 17738519 ~ 17738635 (+)

Expression


Co-expression Network