XLOC_003768 (sos1)


Basic Information

Item Value
gene id XLOC_003768
gene name sos1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 45436703 ~ 45465268 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00007255
atgcagGCTCCGCCCTTTCAGTATGACTTTTACAGTGAGGAGAACGCGCACAAGTGGAGAGGCCTGCTGGTGCCGTCACTCAACAAGgtgctTAATCAGGTGCACCCGAAGCTGTCGTCCCAGCAGGAGGCGCTGCAGTACATCGAGGGGCTGATCTTGGTGCTGCTCAACACACTCTGCCAGGCACAGCCTCGCACTGTACAGGATGTGGAGGAGCGTGTGCAGAGGAGTTTTCCACACCCGATAGAGAAATGGGCGATCGCAGATGCTCAGGCCGCCATcgagaagaggaagaggaggaaccCGCTGGCGCTGCCCGTGGACAAGATACATCCACTGCTCAAGGAGGTTCTGGGCTATAAGATCGACCACCAGGTGTCGGTGTACATCGTGGCGGTGCTGGAGTACATCTCTGCAGACATACTGAAGCTGGCTGGAAACTACGTCAGAAACATCCGGCACTATGAGATCTCACAGCAGGACATCACTGTGGCCATGTGTGCTGAtaaggtgctgaTGGACATGCTCCACCCCATCGAGATCGCCCGCCAGCTCACACTGCTGGAGTCTGACTTCTACAGGGCGGTGCAGCCGTCAGAGCTGGTGGGAAGCGTCTGGACTAAAGAAGATAAAGAGATCAACTCTCCAAACCTGCTGAGGATGATCAGACACACCACCAACCTCACACTCTGGCTGGAGAAGTGTATAGTGGAGACGGAGAATGTGGAGGAGCGTGTGTCCGTGGTGTCGCGTATCATTGAGATCCTGCAGGTCTTTCAGGAGCTCAACAACTTCAATGGTGTGCTGGAGGTGGTGAGCGCCATGAACTCCTCACCCGTCTACAGGCTCGACCACACCTTCGAGcaaATCCCCAGCAGACAGAGGAAGATCCTGGAGGAAGCTCATGAGCTCAGTGAAGATCATTATAAGAAGTATCTGGCCAAGCTCAGGTCCATCAACCCACCCTGTGTGCCCTTCTTTGGCATTTATTTAACGAACATCTTGAAGACGGAGGAGGGAAACCCAGACTTCCTGAAGCGCCACGGCACTGAGCTGATCAACTTCAGCAAGAGGAGGAAAGTGGCCGAGATTACTGGAGAGATCCAGCAGTACCAGAACCAGCCCTACTGTCTGCGGGTGGAGAACGACATCCGGAAGTTCTTCGAGAACCTAAACCCGATGGAGGACATGATGGAGAAGGAGTTCACAGATTACCTGTTCAACAAATCTCTGGAGATCGAGCCGCGCAACGCACGCACACTGCCCAGATTCGCCAAGAAGTACAGCTGTCCTCTGAAGTCTCCGGGGGTCCGTCCGTCCGCGGTGCGGCCGGGAGCGATGCGACACCCGACGCCGCTGCAGAACGAGCCGCGCAAGATCAGCTACAGCCGCATCCCTGACAGCGAGACGGAGAGCAGCGCAGCGTCTGCACCAAACTCCCCCAGAACACCCCTGACACCCCCACCCGCATCCGCTGCATCCACTGACACCTGCAGTGTGTTCGACTCTCCACAGCAGCCCTCCAGCCCGTTCCACTCCaACAGCGAGTGTGTGTTCGCTCCGGTGGCTCTGCCGCACGGCCCACgatccTCTTCAGTGTCCTCTATGATGGGTTTTCTGAGGAATGATGATCCTCCAGTTCCTCCTCCTGTCCCGCCGCGCCGCCGGCCCGAGTCTGCCCCCGCCGAGTCCTCGCCCTCCAAGatgatgTCAACACACCTGGACAGTCCTCCTGCGATTCCCCCTCGTCAGCCGACCAGCAGTAAGGTGTATTCTCCTCGATACTCGCTGACGGATCCTCCGGAGAGCCCACCTCTGCTGCCGCCGCGGGAGCCGGTGCGGACCCCGGACGTGTTCTGCAGCTCGCCGTTACACCTGCAGCCGCCGCCGCCGGGCCGCCGCGCCCCTGAGCTGCAGGCCTTCTTCCCACCACAGACGCCCTCACCGTCACCGCTGGGGCCGCGGAAACACCCGGAGCCGCCGCCGGAGCCCCCACTGGGGCCGCCCGTCCCCCCGCGCCTCAGCACCGCAGGCCCGCCCGCACACATCCCCAAACTGCCCCCAAAAACATACAAGAGGGAGTCAGTGCACCGCGAGGGTCCGCCGCCGCCACTGCTGCTGGAGAACGCCAACcccacatga
>TCONS_00007256
GCTCCGCCCTTTCAGTATGACTTTTACAGTGAGGAGAACGCGCACAAGTGGAGAGGCCTGCTGGTGCCGTCACTCAACAAGgtgctTAATCAGGTGCACCCGAAGCTGTCGTCCCAGCAGGAGGCGCTGCAGTACATCGAGGGGCTGATCTTGGTGCTGCTCAACACACTCTGCCAGGCACAGCCTCGCACTGTACAGGATGTGGAGGAGCGTGTGCAGAGGAGTTTTCCACACCCGATAGAGAAATGGGCGATCGCAGATGCTCAGGCCGCCATcgagaagaggaagaggaggaaccCGCTGGCGCTGCCCGTGGACAAGATACATCCACTGCTCAAGGAGGTTCTGGGCTATAAGATCGACCACCAGGTGTCGGTGTACATCGTGGCGGTGCTGGAGTACATCTCTGCAGACATACTGAAGCTGGCTGGAAACTACGTCAGAAACATCCGGCACTATGAGATCTCACAGCAGGACATCACTGTGGCCATGTGTGCTGAtaagGTGGAGCAGTTCGACCTGATGACCCTCCACCCCATCGAGATCGCCCGCCAGCTCACACTGCTGGAGTCTGACTTCTACAGGGCGGTGCAGCCGTCAGAGCTGGTGGGAAGCGTCTGGACTAAAGAAGATAAAGAGATCAACTCTCCAAACCTGCTGAGGATGATCAGACACACCACCAACCTCACACTCTGGCTGGAGAAGTGTATAGTGGAGACGGAGAATGTGGAGGAGCGTGTGTCCGTGGTGTCGCGTATCATTGAGATCCTGCAGGTCTTTCAGGAGCTCAACAACTTCAATGGTGTGCTGGAGGTGGTGAGCGCCATGAACTCCTCACCCGTCTACAGGCTCGACCACACCTTCGAGcaaATCCCCAGCAGACAGAGGAAGATCCTGGAGGAAGCTCATGAGCTCAGTGAAGATCATTATAAGAAGTATCTGGCCAAGCTCAGGTCCATCAACCCACCCTGTGTGCCCTTCTTTGGCATTTATTTAACGAACATCTTGAAGACGGAGGAGGGAAACCCAGACTTCCTGAAGCGCCACGGCACTGAGCTGATCAACTTCAGCAAGAGGAGGAAAGTGGCCGAGATTACTGGAGAGATCCAGCAGTACCAGAACCAGCCCTACTGTCTGCGGGTGGAGAACGACATCCGGAAGTTCTTCGAGAACCTAAACCCGATGGAGGACATGATGGAGAAGGAGTTCACAGATTACCTGTTCAACAAATCTCTGGAGATCGAGCCGCGCAACGCACGCACACTGCCCAGATTCGCCAAGAAGTACAGCTGTCCTCTGAAGTCTCCGGGGGTCCGTCCGTCCGCGGTGCGGCCGGGAGCGATGCGACACCCGACGCCGCTGCAGAACGAGCCGCGCAAGATCAGCTACAGCCGCATCCCTGACAGCGAGACGGAGAGCAGCGCAGCGTCTGCACCAAACTCCCCCAGAACACCCCTGACACCCCCACCCGCATCCGCTGCATCCACTGACACCTGCAGTGTGTTCGACTCTCCACAGCAGCCCTCCAGCCCGTTCCACTCCaACAGCGAGTGTGTGTTCGCTCCGGTGGCTCTGCCGCACGGCCCACgatccTCTTCAGTGTCCTCTATGATGGGTTTTCTGAGGAATGATGATCCTCCAGTTCCTCCTCCTGTCCCGCCGCGCCGCCGGCCCGAGTCTGCCCCCGCCGAGTCCTCGCCCTCCAAGatgatgTCAACACACCTGGACAGTCCTCCTGCGATTCCCCCTCGTCAGCCGACCAGCAGTAAGGTGTATTCTCCTCGATACTCGCTGACGGATCCTCCGGAGAGCCCACCTCTGCTGCCGCCGCGGGAGCCGGTGCGGACCCCGGACGTGTTCTGCAGCTCGCCGTTACACCTGCAGCCGCCGCCGCCGGGCCGCCGCGCCCCTGAGCTGCAGGCCTTCTTCCCACCACAGACGCCCTCACCGTCACCGCTGGGGCCGCGGAAACACCCGGAGCCGCCGCCGGAGCCCCCACTGGGGCCGCCCGTCCCCCCGCGCCTCAGCACCGCAGGCCCGCCCGCACACATCCCCAAACTGCCCCCAAAAACATACAAGAGGGAGTCAGTGCACCGCGAGGGTCCGCCGCCGCCACTGCTGCTGGAGAACGCCAACcccacatgaacacacacacacactcacagactccACACGTGCGCTCACTGCGAGCAGGAGTGTGTTCAGactcttctgtctgtcctcatcTGTAGCTGTCTGACATCACTGACACATCCagaacagcagcacacacacacacacacacacacacacacacacacacactgtaaataatgcaCTGCAGAGGCGCGTGTCTCTTATTTCCAGCTTGTTTCTGGTCTAAATCTGGAGTCTGTTTAATCCTGAAGCATCTTCAGACGGGCCGGTGTTCAGGGGACATTAGGGAAGCTGAATAATCtgggtaatgtgtgtgttttctctgaaaTCAGATTATTTTACACAAACTCTCTTCATTTGGCCTCATTATGTCTAAAAATACACTCTATCTAGAGCTCATCTAGAAATGCTCCGGATGTGAggagttttagatatttggacttgaattGAGACACAAACTCTGAGTAagacagtgtgtgtgcgtgtgtgcgtgcgtgcgtgcgtgtgtgtgcgtgcgtgcgtgtgtgtgtgtgcatgcgtgtgtgtgcgtgcgtgcgtgtgtgtgtgtgcatgcgtgtgtgtgtgtgtgtgtgcactgcttTTGTGTTTGGAGTTTGATCTTGTTTCTAGTGTGAATATCTGAACCGTCTTAAAGACCCAGTTCACCCATCAGTTCACCCAGTTTTAATCATCAATCAAGTCTTCATTTCCTCCTCATTTAGtaaagtttcttctgttgaacactaaagaagatatttagaagaatgctgtaaaccggtaaccattgactttcatatgatttgttttgtcctacaatggaagtcaatggttaccggtttccaaccttcttcaaaatatcttcttcagtgttcaacagaggaaaggaACTCTTGAAGGTTTGGACACTCGAGGGAGCGTAAATCAAGAGGAATTGTTGATGTTGGGGTGAACTGACCCTGTAAATCAATCTTTTTTTTAGGCTAGTAAATGTTTGATTTTCAGAAATAAGACGTCAGTATTGAAGGAGACTTTGAAGCAAGCTTGTCAGACAAACATGTTTTTGGAATAATATATTGAGGTAAATGAGCTGAAGTGGAGAAACTCCCTATTCAAGACATGAATCAGTGTGGGTCCAGAAATGCTTCATGATTGAAGAGTCTGTAGATTCTCCGACTGAAAACACGGCAGACTCTGAGTGTGAGAAGCGCTTGCTCTGCAGTGTGTGAGCCGTTTTATTTCTCAGATTTGTGAggaaaaagtaaaaaatgcaGATCAGTTTTCAGAATAATGAAGTCAGAGCTGCAGGACTGGCGGGACTCCTCTGACTCTGATGTCGGATTGTTCAGGACTTCTGTTCTGCAGTGTGAGGTTGTAAATGTTGAGCTGCAGAcaggaggacacacacacacacacacacacacacacacacacacatgtgcatctTCTAGAGAAACACACACTGAGATTGTAACTCCAGCTGCAGGATCATAAAGTAGCACTGTGTGAAAGTA
>TCONS_00007257
CCGATAGAGAAATGGGCGATCGCAGATGCTCAGGCCGCCATcgagaagaggaagaggaggaaccCGCTGGCGCTGCCCGTGGACAAGATACATCCACTGCTCAAGGAGGTTCTGGGCTATAAGATCGACCACCAGGTGTCGGTGTACATCGTGGCGGTGCTGGAGTACATCTCTGCAGACATACTGAAGCTGGCTGGAAACTACGTCAGAAACATCCGGCACTATGAGATCTCACAGCAGGACATCACTGTGGCCATGTGTGCTGAtaagGTGGAGGAGGACATCAGTGTGTTCCCTCTGCTGGACGAGGAGCCGTCGGCCACAGAGGAGCAGAGCTACTATGAGCTGGTGAAGACCTTCATGGCGGAGCTGCGGCAATACCTGCGGGACCTCAACCTCATCATCAGGGTCTTCAGAGAGcccttcaacacacacacactgctgttctCAGCACACgatgtGGAGAGCATCTTCAGTCGTATAGTGGATGTACATGAGGTGACGGTGAAGCTGCTGGGCCTCATCGAGGACACGGTGGAGATGACGGACGAGAGCAGCCCGCACCCGCTCGTGGGCTACTGCTTTGAGGACCTCGCTGagGAGCTGGCCTTTGACCCCTACGAGACGTACGCACAGGATATCCTGCGCAGCGGCTTCCATGAGCACTTCCTGAGTCAGCTGTACAAACCTGGAGCCGCCATATACCTGCAGtcgaTCTGCGAGGGCTTTAAGGAGGCTGTTCAGTATGTTCTGCCACGGCTGCTGCTCACTCCAGTCTATCACTGTCTGCACTACTTTGAGATCCTCaag
>TCONS_00007258
AGGTAAAGCCATGAGGAAGTGGGTGGAGTCCATCACGAAGATCATCCAGAGGAAGAAGCAGGCGCAGGCCAGCGGCTCCAGCCACAACATCACCTTCGAGAGCTCTCCGCCCGCCATCGAGTGGCACCTGTGCAGAGCGGGACAGGTGGAGCAGTTCGACCTGATGACCCTCCACCCCATCGAGATCGCCCGCCAGCTCACACTGCTGGAGTCTGACTTCTACAGGGCGGTGCAGCCGTCAGAGCTGGTGGGAAGCGTCTGGACTAAAGAAGATAAAGAGATCAACTCTCCAAACCTGCTGAGGATGATCAGACACACCACCAACCTCACACTCTGGCTGGAGAAGTGTATAGTGGAGACGGAGAATGTGGAGGAGCGTGTGTCCGTGGTGTCGCGTATCATTGAGATCCTGCAGGTCTTTCAGGAGCTCAACAACTTCAATGGTGTGCTGGAGGTGGTGAGCGCCATGAACTCCTCACCCGTCTACAGGCTCGACCACACCTTC
>TCONS_00007259
CCCTGACACCCCCACCCGCATCCGCTGCATCCACTGACACCTGCAGTGTGTTCGACTCTCCACAGCAGCCCTCCAGCCCGTTCCACTCCagatccTCTTCAGTGTCCTCTATGATGGGTTTTCTGAGGAATGATGATCCTCCAGTTCCTCCTCCTGTCCCGCCGCGCCGCCGGCCCGAGTCTGCCCCCGCCGAGTCCTCGCCCTCCAAGatgatgTCAACACACCTGGACAGTCCTCCTGCGATTCCCCCTCGTCAGCCGACCAGCAGTAAGGTGTATTCTCCTCGATACTCGCTGACGGATCCTCCGGAGAGCCCACCTCTGCTGCCGCCGCGGGAGCCGGTGCGGACCCCGGACGTGTTCTGCAGCTCGCCGTTACACCTGCAGCCGCCGCCGCCGGGCCGCCGCGCCCCTGAGCTGCAGGCCTTCTTCCCACCACAGACGCCCTCACCGTCACCGCTGGGGCCGCGGAAACACCCGGAGCCGCCGCCGGAGCCCCCACTGGGGCCGCCCGTCCCCCCGCGCCTCAGCACCGCAGGCCCGCCCGCACACATCCCCAAACTGCCCCCAAAAACATACAAGAGGGAGTCAGTGCACCGCGAGGGTCCGCCGCCGCCACTGCTGCTGGAGAACGCCAACcccacatgaacacacacacacactcacagactccACACGTGCGCTCACTGCGAGCAGGAGTGTGTTCAGactcttctgtctgtcctcatcTGTAGCTGTCTGACATCACTGACACATCCagaacagcagcacacacacacacacacacacacacacacacacacacactgtaaataatgcaCTGCAGAGGCGCGTGTCTCTTATTTCCAGC
>TCONS_00007260
gcAGCCCTCCAGCCCGTTCCACTCCagatccTCTTCAGTGTCCTCTATGATGGGTTTTCTGAGGAATGATGATCCTCCAGTTCCTCCTCCTGTCCCGCCGCGCCGCCGGCCCGAGTCTGCCCCCGCCGAGTCCTCGCCCTCCAAGatgatgTCAACACACCTGGACAGTCCTCCTGCGATTCCCCCTCGTCAGCCGACCAGCAGTAAGGTGTATTCTCCTCGATACTCGCTGACGGATCCTCCGGAGAGCCCACCTCTGCTGCCGCCGCGGGAGCCGGTGCGGACCCCGGACGTGTTCTGCAGCTCGCCGTTACACCTGCAGCCGCCGCCGC
>TCONS_00007261
CAGCCCTCTAGCCCACTCCACTCCagatccTCTTCAGTGTCCTCTATGATGGGTTTTCTGAGGAATGATGATCCTCCAGTTCCTCCTCCTGTCCCGCCGCGCCGCCGGCCCGAGTCTGCCCCCGCCGAGTCCTCGCCCTCCAAGatgatgTCAACACACCTGGACAGTCCTCCTGCGATTCCCCCTCGTCAGCCGACCAGCAGTAAGGTGTATTCTCCTCGATACTCGCTGACGGATCCTCCGGAGAGCCCACCTCTGCTGCCGCCGCGGGAGCCGGTGCGGACCCCGGACGTGTTCTGCAGCTCGCCGTTACACCTGCAGCCGCCGCCGCCGGGCCGCCGCGCCCCTGAGCTGCAGGCCTTCTTCCCACCACAGACGCCCTCACCGTCACCGCTGGGGCCGCGGAAACACCCGGAGCCGCCGCCGGAGCCCCCACTGGGGCCGCCCGTCCCCC

Function

symbol description
sos1 Predicted to enable DNA binding activity; guanyl-nucleotide exchange factor activity; and protein heterodimerization activity. Predicted to act upstream of or within small GTPase mediated signal transduction. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in Noonan syndrome; Noonan syndrome 4; and gingival fibromatosis. Orthologous to human SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1).

GO:

id name namespace
GO:0007264 small GTPase mediated signal transduction biological_process
GO:0000786 nucleosome cellular_component
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0046982 protein heterodimerization activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-070209-128 Predicted to enable DNA binding activity; guanyl-nucleotide exchange factor activity; and protein heterodimerization activity. Predicted to act upstream of or within small GTPase mediated signal transduction. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in Noonan syndrome; Noonan syndrome 4; and gingival fibromatosis. Orthologous to human SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1).

Ensembl:

ensembl_id ENSDARG00000100503

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00007255 False 2142 mRNA 0.60 15 45436703 45463766
TCONS_00007256 False 3647 mRNA 0.53 14 45436709 45465268
TCONS_00007257 False 810 mRNA 0.56 6 45448212 45453725
TCONS_00007258 False 505 lncRNA 0.57 3 45454556 45456610
TCONS_00007259 False 849 mRNA 0.64 3 45461419 45463968
TCONS_00007260 False 332 mRNA 0.65 3 45461853 45463515
TCONS_00007261 True 454 mRNA 0.68 3 45462070 45463638

Neighbor

gene id symbol gene type direction distance location
XLOC_003767 plaat1 coding upstream 10810 45421761 ~ 45425893 (+)
XLOC_003766 NA coding upstream 22906 45412823 ~ 45413797 (+)
XLOC_003764 srsf11 coding upstream 36557 45388126 ~ 45400146 (+)
XLOC_003765 CU459093.1 coding upstream 46627 45389377 ~ 45390076 (+)
XLOC_003763 NA coding upstream 80364 45354855 ~ 45356339 (+)
XLOC_003369 CR854846.2 misc upstream 29313621 16122786 ~ 16123082 (+)
XLOC_003318 CR450764.6 misc upstream 32724707 12711700 ~ 12711996 (+)
XLOC_003317 CR450764.16 misc upstream 32742440 12693967 ~ 12694263 (+)
XLOC_003316 CR450764.11 misc upstream 32751104 12685304 ~ 12685599 (+)
XLOC_003315 CR450764.18 misc upstream 32756675 12679732 ~ 12680028 (+)
XLOC_003761 NA non-coding upstream 100830 45331401 ~ 45335873 (+)
XLOC_003757 CABZ01078080.1 non-coding upstream 199969 45234480 ~ 45236734 (+)

Expression


Co-expression Network