XLOC_004080 (twf2b)


Basic Information

Item Value
gene id XLOC_004080
gene name twf2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 17965098 ~ 17981427 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00007779
TTCCGCAGATCGAGTTTCCAACAGGATTCCCCAGGTAAGATGCTCAAGGGGCGTTGATGTCATTGCGCGGAAGTGAGCAGGACCACAGTGCTGGGCACAGATAGCAGTGCCACTGAAGAAGACAATAGAGAAGGACAACCTGGGAGTCTCAACTGGAATTCACTACTGAGCTGGAGCATCAACGGGGTTCAGGATGTCACATCAGACGGGGATTCACGCAACTTCAGACTTAAGAGAGTTCCTCATAAAGGCCAGAAGAGGAGCTTTCAGAGCACTGAAGATTGTTATAAGGAGCGagcagCTGGTGTTGGGAGCATACAGAGAGGTTTCTCAGAGCTGGGATCAGGACTATGACGCATGTGTTTTGCCTATGCTGGATGGCCTGGAACCCTGTTATATCCTGTACCGGCTCGACTCACACAACCAGCTGGGATATGAGTGGCTGTTTATCTCCTGGTCACCAGACCAGTCTCCAGTGAGGTTAAAGATGGTTTATGCTGCCACTCGAGCCACACTGAAGAAAGAGTTTGGGGGAAGCCACATAAATGATGAAGTGTTTGGAACAGTCCAGGAAGACATCTCTTTTCAAGGTTATCTACGACACCTGTCTTCTTCCTCCTGCCCAGCTCCCCTCACCACTGCTGAGCAACAGCTTCATCAGATCAAAATCACAGAGGACAAAGTGGCACGGGACGAGCGAAGAATTGTTCGCCCTGTTGCCACTGTTAGTGGGCAAGGAAAGACAGAGATCAACGTGGAGAGTAAAAACCCGACTTTGCAGGGTTTAGCATTCCCATTGCAGGAGGAGGCTAAACATGCTTTACAGCAGTTTAAACACAAGCGCATCAATTACATTCAACTAAGGCTAGATACTGAACGAGAGACTATTGAACTGGTCCACACTAGTCCAACAGAGACCAAAGAGCTGCCAAGCAGAATCCCCACTGATGCCCCGCGATACCACTTCTTTCTCTACAAGCACGCACATCAAGGACAGCCTCTGGAAGCTGTAGTTTTCATCTACTCCATGCCTGGGTATAGCTGTAGCATTAAAGAAAGGATGCTCTACTCCAGCTGTAAGAATCGACTGCTGGATGAGGTCGAAAGAGACTATCACATAGAGATCGCCAAAAAGatgGAGATTGAAAGTGGAGACGGGCTGACGGAGGATTTTCTGTATGAAGAGGTATACCCGAAACACCATGCGCTGAGGCAAGCCTTCAGCAAGCCAAAAGGCCCAACAGGGAAACGAGGGAACAAGCGGCTCATCAGAGGAGCTGGAGAGAATGGAGATGAGAGCTAGACTCATAGGcctacagtaaaaacaaaacattttaaatgacatctaATACACGTTTCATTTCACCCTCATTTCTCTGTAGCCAGTTTCTTGCTTAAGCTGTACCTTTCCTTGTTATCATTTTTTATGTTTGACTTTGATAATCTCCTTTCACTCTGATACATATTCTGGCATGGTTTACAAGGCCACATAAAGGTGTTGTTTAGGTGATGATTTTTATGTAATAATTcccaataaaatacattaatctGTCTTATTAAATCTTTTCTTGTCttgttaaaagtaattttatcAGGGCGCTCAACCATTTAACAGAGCAcattttgacttaaaaaaaacgatgtttttgtgtgttatgtttaatgaagcaaaaaaagtttcacagtatttcatataatattttttatttcttcctttaaATTTTTTCTGCATATTTTTGAGAGTAAATATTAGGAAtttattgcactttaagctgaatatcttgcaaaataacttgtaaaatgttatgtaatgtcattatggctaaaaaaagaaaaaataataataattattataaactgattattattatgattaaaaatgcctttcctctgttaaacagcacaacaaataattatttttatgagAATTGAAAGTTTACATGAAGGCTAATTATTTTGCCtctaactgtatatatttcagttatattatatattaaagttGAATAAGTATCTAATGCAGGGATTTTTAAACTGggcttaaaataatattttcgaGTTTCTTACCATACATTATTTTCCAACTGAATTAAAtggtatatttaattattttattaaatcatcattttatttattttaattatgatttatctttatattgttttacagCTGTAAATGCTTATTCTCCAAACACTACATGGAACCAGAGCACTCCCaaacaaacagttttaaaacCCCTGATCTAATAACTGTAAAGctgaaaaacattacacaaaTCACACTGAATTCATAAAAAGTAGTACATTTGATCCACGTACATTTAAAGTTcagtaaaaacacaataaaaattgtcagacattaaaattattttgcaacacattaaaataatggtccattatagttaattttagtaaatgtatttactagcatAACCAAACAATTAGAAATACATTTATTACGGTATTAATTTatctagttaatattatttatgtaagTTAAATGTTAGTTTAAGTCAAttaacagtgcattaactaatgttaaaaagcaaaatgtggtttttattaatgtatatttaatgttgatc
>TCONS_00007780
AGATCGAGTTTCCAACAGGATTCCCCAGGTAAGATGCTCAAGGGGCGTTGATGTCATTGCGCGGAAGTGAGCAGGACCACAGTGCTGGGCACAGATAGCAGTGCCACTGAAGAAGACAATAGAGAAGGACAACCTGGGAGTCTCAACTGGAATTCACTACTGAGCTGGAGCATCAACGGGGTTCAGGATGTCACATCAGACGGGGATTCACGCAACTTCAGACTTAAGAGAGTTCCTCATAAAGGCCAGAAGAGGAGCTTTCAGAGCACTGAAGATTGTTATAAGGAGCGagcagCTGGTGTTGGGAGCATACAGAGAGGTTTCTCAGAGCTGGGATCAGGACTATGACGCATGTGTTTTGCCTATGCTGGATGGCCTGGAACCCTGTTATATCCTGTACCGGCTCGACTCACACAACCAGCTGGGATATGAGTGGCTGTTTATCTCCTGGTCACCAGACCAGTCTCCAGTGAGGTTAAAGATGGTTTATGCTGCCACTCGAGCCACACTGAAGAAAGAGTTTGGGGGAAGCCACATAAATGATGAAGTGTTTGGAACAGTCCAGGAAGACATCTCTTTTCAAGGTTATCTACGACACCTGTCTTCTTCCTCCTGCCCAGCTCCCCTCACCACTGCTGAGCAACAGCTTCATCAGATCAAAATCACAGAGGACGAGCGAAGAATTGTTCGCCCTGTTGCCACTGTTAGTGGGCAAGGAAAGACAGAGATCAACGTGGAGAGTAAAAACCCGACTTTGCAGGGTTTAGCATTCCCATTGCAGGAGGAGGCTAAACATGCTTTACAGCAGTTTAAACACAAGCGCATCAATTACATTCAACTAAGGCTAGATACTGAACGAGAGACTATTGAACTGGTCCACACTAGTCCAACAGAGACCAAAGAGCTGCCAAGCAGAATCCCCACTGATGCCCCGCGATACCACTTCTTTCTCTACAAGCACGCACATCAAGGACAGCCTCTGGAAGCTGTAGTTTTCATCTACTCCATGCCTGGGTATAGCTGTAGCATTAAAGAAAGGATGCTCTACTCCAGCTGTAAGAATCGACTGCTGGATGAGGTCGAAAGAGACTATCACATAGAGATCGCCAAAAAGatgGAGATTGAAAGTGGAGACGGGCTGACGGAGGATTTTCTGTATGAAGAGGTATACCCGAAACACCATGCGCTGAGGCAAGCCTTCAGCAAGCCAAAAGGCCCAACAGGGAAACGAGGGAACAAGCGGCTCATCAGAGGAGCTGGAGAGAATGGAGATGAGAGCTAGACTCATAGGcctacagtaaaaacaaaacattttaaatgacatctaATACACGTTTCATTTCACCCTCATTTCTCTGTAGCCAGTTTCTTGCTTAAGCTGTACCTTTCCTTGTTATCATTTTTTATGTTTGACTTTGATAATCTCCTTTCACTCTGATACATATTCTGGCATGGTTTACAAGGCCACATAAAGGTGTTGTTTAGGTGATGATTTTTATGTAATAATTcccaataaaatacattaatctGTCTTATTAAA
>TCONS_00007781
AGACCAGTCTCCAGTACGTAGGAAACAAACGATAAACTGAAGCGCTCTCACACTCTATAAATAAAATGGACATTTTTACCCTTTGGGTAAAGACATATTTACCCATTGGGTAAAACAAACAAGTGAGTTGCCTTTCTGAATAACAGCAGTGGCCACTTATTCTACTCCACACAGGTGAGGTTAAAGATGGTTTATGCTGCCACTCGAGCCACACTGAAGAAAGAGTTTGGGGGAAGCCACATAAATGATGAAGTGTTTGGAACAGTCCAGGAAGACATCTCTTTTCAAGGTTATCTACGACACCTGTCTTCTTCCTCCTGCCCAGCTCCCCTCACCACTGCTGAGCAACAGCTTCATCAGATCAAAATCACAGAGGACGAGCGAAGAATTGTTCGCCCTGTTGCCACTGTTAGTGGGCAAGGAAAGACAGAGATCAACGTGGAGAGTAAAAACCCGACTTTGCAGGGTTTAGCATTCCCATTGCAGGAGGAGGCTAAACATGCTTTACAGCAG

Function

symbol description
twf2b Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in actin filament depolymerization; negative regulation of actin filament polymerization; and regulation of plasma membrane bounded cell projection organization. Predicted to act upstream of or within negative regulation of actin filament polymerization. Predicted to be located in cytoskeleton. Predicted to be active in actin filament and myofibril. Is expressed in lateral line; otic placode; otic vesicle; and posterior lateral line system. Orthologous to human TWF2 (twinfilin actin binding protein 2).

GO:

id name namespace
GO:0042989 sequestering of actin monomers biological_process
GO:0010976 positive regulation of neuron projection development biological_process
GO:0051016 barbed-end actin filament capping biological_process
GO:0030837 negative regulation of actin filament polymerization biological_process
GO:0030042 actin filament depolymerization biological_process
GO:0010591 regulation of lamellipodium assembly biological_process
GO:0005884 actin filament cellular_component
GO:0030016 myofibril cellular_component
GO:0005737 cytoplasm cellular_component
GO:0051015 actin filament binding molecular_function
GO:0003779 actin binding molecular_function
GO:0003785 actin monomer binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050522-238 Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in actin filament depolymerization; negative regulation of actin filament polymerization; and regulation of plasma membrane bounded cell projection organization. Predicted to act upstream of or within negative regulation of actin filament polymerization. Predicted to be located in cytoskeleton. Predicted to be active in actin filament and myofibril. Is expressed in lateral line; otic placode; otic vesicle; and posterior lateral line system. Orthologous to human TWF2 (twinfilin actin binding protein 2).

Ensembl:

ensembl_id ENSDARG00000009727

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00007779 False 2581 mRNA 0.37 11 17965098 17981427
TCONS_00007780 False 1540 mRNA 0.46 10 17966118 17981421
TCONS_00007781 True 513 lncRNA 0.45 4 17974191 17977065

Neighbor

gene id symbol gene type direction distance location
XLOC_004079 cishb coding downstream 573 17959507 ~ 17964525 (-)
XLOC_004078 CR589944.2 coding downstream 56416 17906902 ~ 17908682 (-)
XLOC_004077 uba3 coding downstream 161961 17785182 ~ 17803137 (-)
XLOC_004076 tmf1 coding downstream 182168 17757342 ~ 17782930 (-)
XLOC_004075 eogt coding downstream 209654 17726649 ~ 17755444 (-)
XLOC_004081 qrich1 coding upstream 15976 17997403 ~ 18107447 (-)
XLOC_004082 LO018315.7 coding upstream 162858 18144285 ~ 18148488 (-)
XLOC_004083 mustn1b coding upstream 268382 18249809 ~ 18253111 (-)
XLOC_004084 stimate coding upstream 288886 18270313 ~ 18283886 (-)
XLOC_004085 SFMBT1 coding upstream 302521 18283948 ~ 18323059 (-)
XLOC_004063 CR854846.1 misc downstream 1837420 16127382 ~ 16127678 (-)
XLOC_004019 CR450764.8 misc downstream 5273407 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 5343331 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 5373802 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 5451836 12512966 ~ 12513262 (-)
XLOC_004073 NA non-coding downstream 735245 17223850 ~ 17229853 (-)
XLOC_004072 CR769769.3 non-coding downstream 817637 17144309 ~ 17147461 (-)
XLOC_004071 CR769769.2 non-coding downstream 867165 17093753 ~ 17097933 (-)
XLOC_004070 NA non-coding downstream 873903 17081422 ~ 17091195 (-)
XLOC_004092 NA non-coding upstream 868499 18849926 ~ 18852369 (-)
XLOC_004093 NA non-coding upstream 1106987 19088414 ~ 19091101 (-)
XLOC_004095 CT737428.1 non-coding upstream 1199025 19180452 ~ 19180555 (-)
XLOC_004096 BX511159.1 non-coding upstream 1434751 19416178 ~ 19416315 (-)

Expression


Co-expression Network