XLOC_004776 (cdk5r1b)


Basic Information

Item Value
gene id XLOC_004776
gene name cdk5r1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 28367557 ~ 28370484 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009445
ACTGCTCTCAGCATCACCAACCGAAGGAGACATCCAGCATCCCTAGACCACGGGAGAGACCTCCGACGAGACGTggaatgcttttttttatttgatttgattaaaagCCTGCTGTTTTATTGGAATTTAGGCTTTCTGTCCGTCTTGATATTAAATCTTTTTCTTGTGTGGATGATTTTGCATCTCCTTGATGCGCAGTGTTATCAAGGATAAACCCAGACAGCCATTACTGCGGCTCTTGTTTTGCTAAAGCATCGTGGAGGCGAGCAGATTTCCTGCTTTGCAGTAACCGAGCCCTCATCCATCGCAACAGCATTCTTCCTTAAATAGAACACCAACCTAAATTTGGATGTCTAACAGATTGAACTAGTCTCAGGAAGCAGTGGGCTCCGGTTTGGCGCCTTCTTTAGCTGACCCCTAACCTTGAGTTCCTGATATCCCACTCCCGGCATCATGGGAACCGTGCTATCACTTTCACCCAGCTACCGGAAGGCTGCCCTGTTCGAAGATGGCCCGGCCACAGTGGGCCACTACACGGCGGTTCAGAACAGCAAGAACGCCAAAGACAAGAACCTAAAACGGCACCCACTCATCAACGTACTGCCATGGAAGCGAATAGTAGCCGTTTCAGCCAAGAAAAAGGGGTCTAAGAAGGTGCAGCCAAACACCACCTACCAGAACAATGTTTCTCACCTTAACAATGAGAACCTCAAGAAGTCCCAGTCATGTGCAAATCTCGCCTCCTTTACGCAGGACCAGACAAGTCCGTCAAACCAAGGCTCCAAAAACTCCAACAACACAGCTTCCTCGGTCAAGAAAGCACCTCTTTCCAACTCCAACGCTGTCCCTGGGACACCCAAGAGGGTGATCGTTCAGGCCTCCACCAGCGAGCTTCTGCGTTGTCTTGGGGAGTTCCTCTGCCGGAGGTGCTATCGGCTCAAGCATCTGTCCCCTACAGACCCGGTATTGTGGCTCCGCAGCGTGGACCGTTCTTTGCTCCTGCAGGGCTGGCAGGACCAGGGATTCATCACCCCGGCCAATGTAGTTTTCGTCTACATGCTCTGCCGAGACGTGGTCTCCTCTGAGGTGGCCACAGAGCACGAGCTGCAGGCCGTCCTACTGACCTGCCTCTACCTGTCTTACTCATACATGGGCAATGAGATCTCGTACCCTCTCAAGCCATTCCTTGTGGAGACCTCCAAGGAGACATTCTGGGACCGCTGTCTGTCCATCATAAATTTGATGAGCGCCAAGATGCTGCAGATCAACTCGGATCCTCACTATTTCACCCAGGTCTTTGCGGACCTTAAAAACGAGAGCCAGAAGGAGGAGGAACGGAGTCGTCTGCTTATCGGCCTGGACCGGTGAGGGGGCTTTGGAGATGT

Function

symbol description
cdk5r1b Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity and kinase activity. Acts upstream of or within amacrine cell differentiation; embryonic retina morphogenesis in camera-type eye; and retina layer formation. Predicted to be located in plasma membrane. Predicted to be part of protein kinase 5 complex. Is expressed in basal plate midbrain region and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1).

GO:

id name namespace
GO:0035881 amacrine cell differentiation biological_process
GO:0016310 phosphorylation biological_process
GO:0060041 retina development in camera-type eye biological_process
GO:0010842 retina layer formation biological_process
GO:0060059 embryonic retina morphogenesis in camera-type eye biological_process
GO:0016533 protein kinase 5 complex cellular_component
GO:0016740 transferase activity molecular_function
GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040718-220 Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity and kinase activity. Acts upstream of or within amacrine cell differentiation; embryonic retina morphogenesis in camera-type eye; and retina layer formation. Predicted to be located in plasma membrane. Predicted to be part of protein kinase 5 complex. Is expressed in basal plate midbrain region and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1).

Ensembl:

ensembl_id ENSDARG00000045087

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009445 True 1385 mRNA 0.52 2 28367557 28370484

Neighbor

gene id symbol gene type direction distance location
XLOC_004775 LO017791.1 coding upstream 67628 28298859 ~ 28299929 (+)
XLOC_004774 CABZ01027646.1 coding upstream 185837 28117365 ~ 28181720 (+)
XLOC_004773 cacna1g coding upstream 293995 27704015 ~ 28073562 (+)
XLOC_004772 spata20 coding upstream 701966 27589607 ~ 27665591 (+)
XLOC_004771 etv4 coding upstream 798863 27536095 ~ 27568694 (+)
XLOC_004777 NA coding downstream 6546 28377030 ~ 28381255 (+)
XLOC_004778 tbkbp1 coding downstream 204379 28574863 ~ 28678323 (+)
XLOC_004779 NA coding downstream 247217 28617701 ~ 28617965 (+)
XLOC_004780 tbx21 coding downstream 378705 28749189 ~ 28770817 (+)
XLOC_004781 pnpo coding downstream 429504 28799988 ~ 28807184 (+)
XLOC_004762 dre-mir-10a non-coding upstream 1232590 27134869 ~ 27134967 (+)
XLOC_004754 BX469896.1 non-coding upstream 1470941 26894321 ~ 26896616 (+)
XLOC_004752 NA non-coding upstream 1533365 26737431 ~ 26834192 (+)
XLOC_004751 NA non-coding upstream 1675506 26691819 ~ 26692051 (+)
XLOC_004748 NA non-coding upstream 1774259 26589644 ~ 26593298 (+)
XLOC_004786 NA non-coding downstream 563040 28933524 ~ 28946150 (+)
XLOC_004791 AL732488.1 non-coding downstream 643089 29013573 ~ 29013690 (+)
XLOC_004796 NA non-coding downstream 942081 29312565 ~ 29373414 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00016745 cdk5r1,LOC108426451 coding CM030122.1 CM030122.1 29328529 ~ 29329440 (+)