ephb4a (ephb4)


Basic Information

Item Value
gene id ephb4a
gene name ephb4
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053127.1
NCBI id CM020924.1
chromosome length 37730433
location 22341196 ~ 22381203 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039777803.1
GGTGCCATTCGACTCCGGCTTTGATGCGGTGATGAAGTCCTCAGTGACCAACGTACAGTGTCAGCCCTACGAGCTACTTTAGCGCACAACTTTTAGTAGCCGCTGTTGGTCCAGTCTGCTGACTTATCCAGAGAACATTTACCCCAGTTTCAGTCTAATTTTCGCCTGTTAATCCAGGCCAGGCTAGACGTGTCGCGCAGTATCCCCACCACCTTTcgtggattttttttctccccccgcAGCCCTAGCTAATAGTCTGGTGCtttaagaggaaaaaaaggaaaaacacactTTCGCGGATTGTTTTGCCGAACATGACGAGAAGATGTGGAAGTAGGTATGAACCGACTGATAAGGAGGAGTATCTCTGCAACTAACACATATGCAGTGAGGTGCCCTGGTTGCGGATTCAGGCTGCTCGATCATCAGGCTGAGGGGGAGAATTTGGGAGAAGTCGCATGGAGCACAAAGCCGAGGATACAACAAGTTTGGACCATGCACCCCTTGTGCTGACAGAGGACTGAGGTGGAAGAGGAGTTGAAACGCTGAAGCATGTTTCTGACTGTTGTTCTTCTGCCCATACTTTCACCACAACACAAAGTTGGACAATTCATAGAAGTTTCGAGTCCGTGCTAACACTTGCTATTTAAGGTGCTGCGGCCGACCAGTTAAACGTGCTTTTAGATTCACAATTCGTCTGAATCCGCACTTAgcaaaagtgtattttttttttttactgcagtgTTGTGTGAGGCTCTCCGAACTGAAGTCCACTTTAAATGCGGACTGGTTTGCGGTCAGTCAGTGCACAGCCGAGCTGCCAGTGCCACTTGATTTTTAATTTACGGCAAAACAGAAGTCGGTTCATTTTTTACCATTTAGTGACAGAACTATGGAGCTGACATACAGGatcattgttctgctggggtgCATCTTCCTGGACTGGGCTCTTCTGGCTTCTGCAGAGGAAGAGGTCCTGATGAACACTAAAACGGAGACTTCTGATCTCAAATGGACCATCTTCTCACATGCCAAACCCGAGTGGGAGGAAGTAAGCGGTTTAGATGAGGAAAACAACAGTGTGAGGACCTATCAGATCTGTCAGACTGACAGCTCATCCAGCCATTGGCTGCGCAGCGGCTTCATCCAGCGACGTGGAGCGTCTCAGGTTTACGTGGAACTGCGATTCACCATGATGGAGTGTTCATCCAGGAGCACCCACCACCGCAGCTGTAAGGAGACCTTTAACCTGTACTACTACCAGGCAGACTCCAACGAGGCCACGTCCTCTTACCCGCCCTGGATGGAGAACCCATACACCAAGGTGGACACAGTGGCTGCAGACTTTCTTCTGAGGAAGGGTGGGGAGCGGAAATTCAATGTGAAGACCTTAAGACTCGGCCCTCTATCTAAGAGAGGCTTCTACTTGGCTTTTCAGGCTCAGGGTGCCTGCATGGCCCTGCTGTCAGTCAGGGTGTTCTTCAAAAAGTGCCCCCCCCTGGTCAGtgctctttcctctttccccGAGACTGTTCCCCGTACTCTGGTGCAAGAGgcgcagggtgtgtgtgtggagcacgCGGCCCAGCAAGGGCCCCGACCTCGGCCACCTAAGCTCTTCTGCGGGGAAGATGGCCAGTGGGTGGGCCAGCCAACAACCTCCTGCGCCTGCCTACCAGGATTTGAGTCTGCCGAAGGACACACTAGATGCACAGGCTGTCCTGTGGGTCAGTTCAAGTCGACCTCAGAGGGACAGTGCACAGGCTGTCCAGGATTCAGCCACGCCGCCATGGGAGGGGCGACGGTGTGTGCGTGTCGCTCCGGATACTTGCGTGCAGAGTCTGAATCTCCCAACATGCCGTGCACTAGACCTCCCTCGGCTCCGCGCAGCATCGTCACCCAGATCAACGACACCACGCTCAGTCTGGAGTGGAACGAGCCCTTGGACAACGGCGGCAGAACAGACCTGAGCTACTCCGTCACATGCTCTGTGTGCAGGTCACCGAAGGGGCCGTGCCTCTCCTGCGGAGACAGCGTCAGCTACCGGCCCGCGCAGCACGGCCTGCTGGGTCGTAGGGTGGAGGTGTGGGGCCTGCTGCCTCACACCACATACACGTTCACAATCCAGACGCTCAACGGGGTGTCTCAGGTCAGCGGAAAGGACCCTGGCAGTGAAAGCGTCAACATCACCACAAGCCATGACGTGCCATCTCTGGTTTCTGTGATTCAGAAGAGTGACTCCACAGAGAGCAGTCTGACTCTGCACTGGCCAGTCCCGGCTCAGCCACACTACACCATCCTGCAGTATCAGCTACGCTACTGTGAGAAGGAGCGACGTAGTGAAGATCAGTGTCACTACACAGAGAGTAACAGAAACCAGGCCGTGCTGACGGACCTCCGCAGGGCCACTCAGTACGAGGTGCAGGTTCGGGCGCGCACCATGGCCGGTTATGGCAGCTTCAGTCGTGCAGCCGTGTTCCGCACGCTGCCTGATGGTCATGACTCCGCCGCTCAGTTCTTAGTACCTGGAATCCTTATCGCTGTTGGGATGCTGCTGCTTGTCACTTTCGTCTTAGTGGCCGCCTACTGCATACGCAGACACAGCCGAGTGAAGGATCCAGAGCTGAGCGACAAAAACAGCCAGTACCTTGTTGGCCAAGGGGTCAAGGTCTATATCGACCCCTTCACCTATGAGGACCCTAATGAGGCCGTGCGAGAATTTGCCAAGGAAATTGATGTTTCCTTTGTCAAGATCGAGGAGGTTATCGGTGCTGGAGAGTTCGGGGAGGTGTGTCGAGGGCGGCTGAAGATCccagggaaaaaagaaaactacGTAGCAATTAAGACGCTAAAAGGAGGCTACACTGACAAGCAGAGACGGGACTTCCTTTCTGAAGCGTCCATCATGGGTCAGTTCCAGCACCCCAACATCATCCACCTGGAGGGGATCATCACAGCCAGCTGTCCAGTCATGATCCTCACAGAGTTTATGGAGAACGGAGCTCTGGACTCTTTTCTACGGCTGAACGACAGCCAGTTCACTCCCATCCAGCTGGTGGGTATGCTGCGCGGCATCGCCTCCGGCATGAAGTACCTGGCAGAGATGAGCTACGTCCACCGAGACCTGGCTGCTCGCAACATCCTGATCAACAGCAACCTTGTGTGCAAGGTGTCCGACTTCGGCTTGTCACGCTTCCTGCAGGAGAACTCCTCTGATCCGACCTACACCAGCTCTTTGGGTGGTAAGATCCCAATCCGCTGGACAGCGCCGGAGGCGATCGCCTTCAGAAAGTTTACCTCAGCCTCAGATGTGTGGAGCTATGGCATTGTCATGTGGGAGGTCATGTCTTTTGGAGAGAGACCGTACTGGGACATGAGCAACCAGGATGTAATCAATGCCATAGAGCAGGACTACCGGCTGCCACCGCCCCCTGACTGCCCCACCCATCTGCACCAGCTGATGCTGGACTGCTGGCAGAAGGACCGCTCGGCGCGCCCTCGTTTCGCGGACATTGTCAGTGCTCTGGACAAGCTGATCCGCAACCCTGCATCGCTGAAAATAGTGGCTCAAGAAGGCGCAGGGCCGTCTTACCCCCTGCTGGACCAGCGTGCACCTTTAGCCCTCTCACCGTGTGCTTCAGTCGGAGAATGGCTGAGGGCAATCAAGATGGAGCGCTACGAAGACAGCTTCCTGCAGGCCGGCTTCAACTCAGTGGACCAGCTGGCCCAGATCACCACACAGGATCTACTGCACATGGGAGTGACTTTGGCCGGGCACCAGAGGAAAATCCTTTCCAGCATCCAGACAATGACTTTTCGGAGCAAGAGCACTGCAACTGTGAGCTTCTAGCTCACCTGTCTCCTAACCTGGACGTGCAGCCATGTACTGGAGTACTGTGGATCCTCTCCTGTGACCCACTTTGAACACGGACTCCAAGGGAGCTTGGCAGAATTAACTATGACCAGAATCTTTTTGACTAAACATGACATTCCCATCCGGATGAGAAAGTCGTTTAGAGACGGGCGAGTCCCTTTCGTTCAAAGGGACCAGGAGATGAAGTTGACTAATTTTTAcagtttgtggtgtttttttgtggaCCTGAAGTCAGGACCCAATACATGTGCTAAACCAAGAGGAGAGACCGATCAGAGTTTACAAAGTTTCTGTAGTATCATGTCATTTTGGAAACAGACAGTCGACTGTTTTGTTGTCGAGTAAAAAGTCACTTCACCaaaggagacaaaaagaaaTGCCAGTGCCAATCCAAGGATTTCAGTTTTCATATCCGTGTGTAATTATGAATGAGAACTGCTTTCACCCTGGGTGTCTTGCATCAAATCCATCTGGATTACATTACTACGTAGACATTTTTCACATCAAGACCGAACATTTTAACAGTTGGATTTCACTTCTTTGTTTCCATTTGATTTCAACATTACCTCCTCTTCTCTCAGGTGTGATGTGTAATGCAAACTTTGGAGAGCACTGTACTCCTAGTCCTAATCAGACTTCTCTCATCTTCTTCGGTCTCTCCCCTAATCGGCTCCACGGAGCGTGAGGGGAAGAGAGACATATCAGCACTTTTGTCATTTCAGAGTGAATTGTAGTCTTCAGTAACTCCATGTGTTTCTCTCGGAGTGTGGTTGGTTATTTCTACTGCCTGTGTTTCTGCTGGCAGCTCAGTTTTATTATACTTAGACTGAACAAGGACCAAGTGGACTCAGAGACCAGAGATCACTGTACAGTCGGTTTTCTTTGTTGTACCGAGGAAGCTATCTGGCCTCCAACTTGTTTTTCTTGATATAACGGATGCATTTTTAATTCTCTTATTCTGTATTCTCCATCTTCCAGTGCCATTCAGTTGTCTTTGTGGACTTAAATGCCAATTTTATGAAGCAGAAATCTCATGAGTGATTCTTCTTGTCTCATTAAAATGTACCTCAAAGGGttactttgaca

Function

symbol description
ephb4 Enables ephrin receptor activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; ephrin receptor signaling pathway; and protein autophosphorylation. Is integral component of plasma membrane. Implicated in hereditary lymphedema.

NR:

description
ephrin type-B receptor 4 isoform X1

GO:

id name namespace
GO:0018108 peptidyl-tyrosine phosphorylation biological_process
GO:0048013 ephrin receptor signaling pathway biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0005003 ephrin receptor activity molecular_function

KEGG:

id description
K05113 EPHB4, HTK; Eph receptor B4

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039777803.1 True 4960 mRNA 0.52 17 22341196 22381203

Neighbor

gene id symbol gene type direction distance location
LOC120544364 dlg4,LOC102775934,LOC101463677,LOC107386432,LOC107093504 coding upstream 7871 22265010 ~ 22333325 (+)
si:dkey-251i10.1 LOC104931197,LOC103353321,LOC101464643,LOC102200398 coding upstream 125908 22212857 ~ 22215288 (+)
zgc:175280 slc7a1,LOC102202414 coding upstream 207377 22128250 ~ 22133819 (+)
gsx1 gsx1,LOC102779870 coding upstream 255739 22083968 ~ 22085457 (+)
LOC120544110 zfx,LOC101469595,LOC102299651,LOC100691538 coding upstream 325518 22002808 ~ 22015678 (+)
xrra1 NA coding downstream 46136 22427339 ~ 22432587 (+)
LOC120543726 pak3,LOC103353309,LOC103475835,LOC103141826,LOC107093501 coding downstream 100372 22481575 ~ 22512174 (+)
LOC120544485 LOC102796686,LOC101483903,LOC104935288,LOC100691539,LOC101070532,LOC103353305 coding downstream 186297 22567500 ~ 22573747 (+)
klhl13 klhl13,LOC103475825,LOC106563441,LOC101069997,LOC104946894 coding downstream 279041 22660244 ~ 22699965 (+)
si:ch1073-224n8.1 LOC103353299,LOC102794175 coding downstream 335515 22716718 ~ 22721292 (+)
G167651 NA non-coding upstream 113898 22218081 ~ 22227298 (+)
G167649 NA non-coding upstream 124732 22215533 ~ 22216464 (+)
G167569 atp6v1a,LOC106526133,LOC108236878,LOC100710668,LOC101468244 non-coding upstream 309556 22030297 ~ 22031640 (+)
G167564 LOC104935632,LOC104965992,LOC103353333 non-coding upstream 323291 22016075 ~ 22017905 (+)
G167559 map7d2 non-coding upstream 358944 21981342 ~ 21982252 (+)
G167670 spag7 non-coding downstream 68667 22449870 ~ 22452122 (+)
G167711 NA non-coding downstream 73016 22454219 ~ 22455752 (+)
G167717 NA non-coding downstream 79344 22460547 ~ 22463330 (+)
G167774 NA non-coding downstream 327898 22709101 ~ 22712803 (+)
G167818 NA non-coding downstream 435546 22816749 ~ 22819328 (+)
kif20a kif20a,LOC102778170 other upstream 196997 22134507 ~ 22144199 (+)
sms sms other upstream 493098 21823653 ~ 21848098 (+)
LOC120544341 LOC108236972,LOC106514048,LOC103368261 other upstream 570442 21764201 ~ 21770754 (+)
dnajc18 dnajc18,LOC101477689,LOC100707186,LOC104924601 other upstream 620331 21713943 ~ 21720865 (+)
LOC120544614 LOC103368254,LOC101478346,LOC103475446,LOC100706924,LOC104924602 other upstream 630819 21680133 ~ 21710377 (+)
LOC120544391 LOC106960928,LOC103141750,LOC106923483,LOC103475842,LOC104941830,LOC102202980,LOC105919900,LOC100693698,LOC101158965,LOC101487699,LOC102291410 other downstream 13313 22394516 ~ 22422054 (+)
zgc:163098 LOC103353302,LOC100691810,LOC102795692 other downstream 240190 22621393 ~ 22645826 (+)
gria3a gria3,LOC103367234,LOC103395443,LOC102795589,LOC101486592 other downstream 1460330 23841533 ~ 23918477 (+)
G168226 thoc2 other downstream 1546139 23927342 ~ 23928481 (+)
gab3 NA other downstream 2029102 24410305 ~ 24420345 (+)

Expression


Co-expression Network