| Item | Value |
|---|---|
| gene id | XLOC_005231 |
| gene name | stat5b |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007123.7 |
| NCBI id | CM002896.2 |
| chromosome length | 49182954 |
| location | 13560082 ~ 13650472 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| stat5b | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; defense response; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated and signal transduction. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in growth hormone insensitivity syndrome with immune dysregulation 1 and growth hormone insensitivity syndrome with immune dysregulation 2. Orthologous to human STAT5A (signal transducer and activator of transcription 5A) and STAT5B (signal transducer and activator of transcription 5B). |
| id | name | namespace |
|---|---|---|
| GO:0019221 | cytokine-mediated signaling pathway | biological_process |
| GO:0006355 | regulation of transcription, DNA-templated | biological_process |
| GO:0042127 | regulation of cell population proliferation | biological_process |
| GO:0006952 | defense response | biological_process |
| GO:0060397 | growth hormone receptor signaling pathway via JAK-STAT | biological_process |
| GO:0007259 | receptor signaling pathway via JAK-STAT | biological_process |
| GO:0043434 | response to peptide hormone | biological_process |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | biological_process |
| GO:0007165 | signal transduction | biological_process |
| GO:0005829 | cytosol | cellular_component |
| GO:0005634 | nucleus | cellular_component |
| GO:0005737 | cytoplasm | cellular_component |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | molecular_function |
| GO:0003677 | DNA binding | molecular_function |
| GO:0003700 | DNA-binding transcription factor activity | molecular_function |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | molecular_function |
| id | description |
|---|---|
| ko04012 | ErbB signaling pathway |
| ko04630 | JAK-STAT signaling pathway |
| ko04217 | Necroptosis |
| ko04658 | Th1 and Th2 cell differentiation |
| ko04659 | Th17 cell differentiation |
| ko04062 | Chemokine signaling pathway |
| ko04917 | Prolactin signaling pathway |
| ko04935 | Growth hormone synthesis, secretion and action |
| ko05200 | Pathways in cancer |
| ko05207 | Chemical carcinogenesis - receptor activation |
| ko05203 | Viral carcinogenesis |
| ko05221 | Acute myeloid leukemia |
| ko05220 | Chronic myeloid leukemia |
| ko05223 | Non-small cell lung cancer |
| ko05166 | Human T-cell leukemia virus 1 infection |
| ko05161 | Hepatitis B |
| ko05162 | Measles |
| ko04933 | AGE-RAGE signaling pathway in diabetic complications |
| ko03000 | Transcription factors |
| id | description |
|---|---|
| ZDB-GENE-040818-1 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; defense response; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated and signal transduction. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in growth hormone insensitivity syndrome with immune dysregulation 1 and growth hormone insensitivity syndrome with immune dysregulation 2. Orthologous to human STAT5A (signal transducer and activator of transcription 5A) and STAT5B (signal transducer and activator of transcription 5B). |
| ensembl_id | ENSDARG00000055588 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00010074 | False | 2726 | mRNA | 0.46 | 20 | 13560082 | 13650472 |
| TCONS_00010076 | False | 3528 | mRNA | 0.44 | 19 | 13564357 | 13650344 |
| TCONS_00010075 | False | 3525 | mRNA | 0.44 | 19 | 13564357 | 13650344 |
| TCONS_00010077 | True | 1433 | nonsense_mediated_decay | 0.48 | 12 | 13603739 | 13650290 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_005230 | CR354395.2 | coding | downstream | 3546 | 13553730 ~ 13556536 (-) |
| XLOC_005229 | ghdc | coding | downstream | 10544 | 13527422 ~ 13549538 (-) |
| XLOC_005228 | lsm5 | coding | downstream | 223045 | 13331526 ~ 13337037 (-) |
| XLOC_005227 | emc9 | coding | downstream | 241113 | 13311939 ~ 13318969 (-) |
| XLOC_005226 | pelo | coding | downstream | 354228 | 13188616 ~ 13205854 (-) |
| XLOC_005232 | foxh1 | coding | upstream | 71913 | 13722385 ~ 13730501 (-) |
| XLOC_005233 | adam11 | coding | upstream | 161159 | 13811631 ~ 13886952 (-) |
| XLOC_005234 | dbf4b | coding | upstream | 238198 | 13888670 ~ 13905307 (-) |
| XLOC_005235 | klhl11 | coding | upstream | 310796 | 13961268 ~ 13966184 (-) |
| XLOC_005236 | aclyb | coding | upstream | 322586 | 13973058 ~ 14078070 (-) |
| XLOC_005224 | NA | non-coding | downstream | 453859 | 13102866 ~ 13106223 (-) |
| XLOC_005222 | BX572641.1 | non-coding | downstream | 1224751 | 12335216 ~ 12335331 (-) |
| XLOC_005214 | NA | non-coding | downstream | 2787136 | 10769131 ~ 10772946 (-) |
| XLOC_005200 | NA | non-coding | downstream | 3430180 | 10124660 ~ 10129902 (-) |
| XLOC_005199 | BX928755.1 | non-coding | downstream | 3496414 | 10060636 ~ 10063668 (-) |
| XLOC_005237 | NA | non-coding | upstream | 487814 | 14138286 ~ 14144159 (-) |
| XLOC_005240 | NA | non-coding | upstream | 1189315 | 14839787 ~ 14840559 (-) |
| XLOC_005243 | NA | non-coding | upstream | 1467415 | 15117887 ~ 15120113 (-) |
| XLOC_005244 | NA | non-coding | upstream | 1474937 | 15125409 ~ 15126049 (-) |
| XLOC_005246 | NA | non-coding | upstream | 1592095 | 15242567 ~ 15244000 (-) |