XLOC_006100 (hif1aa)


Basic Information

Item Value
gene id XLOC_006100
gene name hif1aa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 31757331 ~ 31783663 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012032
ATGGAGGCAGTCGCACCTGGGAAAAAAAGGGTGAGTTCAGAGCGAAGGAAGGAGAAATCCAGAGACGCAGCACGTTGTCGGAGAGGAAAAGAGTCTGAGGTGTTTTATGAGCTGTCCAGAGAACTCCCTCTCCCCCACAGCGTCACCTCTAACCTGGATAAAGCATCGGTCATGAGACTGGCTCTCAGTTACCTGCGCCTGCGTAAACTGCTGAACAGCGaTGTGCTGGAGAAGGAGACTGCATTAGACACTCAGTGGAACGGTTCATTTCTGAAAGCTCTGGACGGGTTTCTTTTGGTTCTTTCAGCTGATGGTGATATTGTCTACCTTTCAGAGAATGTCAGCAAGTGCTTGGGCCTTCCTCAGATTGAACTCACTGGTCACAGTGTGTTTGAGTTTACTCATCCGTGTGACCATGAGGAGCTCAGAGAAATGCTGGCACACAGATTTGGTCTGTCTAAGAAATCGAAAGATCAAAACACAAACAGAAGTTTCCTGCTGAGGATGAAATGCacgctgaccagcagagggcgCACTGTCAATGTTAAATCTGCCTCCTGGAAGGTGCTGCGCTGTTCGGGCCGTATCCACACAGCAGATGGTGTTGAGAAGGAGGTGTGTGAAGAAAAAAACACGTGTTCGACGTACCTGGTGCTCATCTGCGAGTCTATTCCCCATCCGGCGAACATTGAGGCTCCTCTGGATTCCAGAACGTTCCTCAGCCGCCACACTTTAGACATGCGCTTCACCTACTGTGATGAGAGGATCACAGAGCTCTTGGGTTTTGATCCAGAGGATGTGTTACAGCATTCTGTGTATGAATACTATCATGCGTTGGATTCAGACCACATGACCAAAACACACCACAGCCTTTTTGTGAAGGGGCAAGTGTGTACCGGACAGTACCGTCTGCTGGCTAAAGCCGGAGGGTTTGTTTGGGCAGAGACTCAGGCCACTGTGATCTATAACAGTAAAAACTCTCAGGCACAGTGTGTGGTTTGTGTCAACTACATCCTCAGTGGCATTGAACAACCCAAACAAATCCTGTCGCTTCAGCAAACCaacagcacaaaaataaaacaggaaGAACACCAGGAGGAGGTTGAGGTGACCATGGCAGAGTTGAAAGAGGAGGAAAAGGAGATGGACAAAGAAGATGAGGAGTGTGTGCAGCCTGTAGTGCAACATAACAGCCTGAAGGGGGAGACAGAGGCGCTGACTGTAGCAGATCCTGTTCTCACGCTGGATATCAACATCACTGACTCAGCGATCTCTGTCCTGACAGAAATTCCTCTCTACAACGATGTCATGTTGCCCTCTTCAGATGTCCTGCTCCCCCTCTCGCCCCTATCTCCCCCGTGCTCCTCTCTAAATGATGATGAAGCCTCCACAGGCCATCTACAACACGACCAATTCCCTTTCCAACAGTCCTCTGACTCCTCCAGATCACAGGTTGATCTACCGGTGGATTCAGAACTatgtgaccagctaaaaccagatcACGTTGAGAAACACTTTTCCATGGATATAGAGTCCAAGACACAGGGAGTGGGTTTGGATCTGGAGATGTTGGCTCCATACATTCCCATGGATGATGACTTCCAGCTGCGGACTGTTTCTCCAGTCAGGCCCATGTGCTCCAGTCCATGTTCAGGGCTTGATCTGACCCCGTCCAGCAGCACACAAACCAGCCCTGCTCTTTCGGCAGCCACTCCAGATTCGCTATCCTGTGATCCCGtgcagcagaaaaacaaaaccaCAGTGCAGGACCACAGCAGAGAAATTATTCAAGACAGTGATATTTCTTATAAATGTCAGACCAACCCGAAGCTACTCAAGAGGAAACTCGAGACCATACCGCTGTCTGAAGCAATAAGACTGGGGTCTGTGCTGCAGGTTGTTACCGATTTTCCAGAGAAAAAGGTCCGCAAAACAGATGCTCCATCATCAGAAGGAATTCGTCATGCTACGATACTGTTGCTGCCATCCAATGTTGCAAGTCGGTTATTGAGCAGATCGTCAGAGGGCGGAGCCATAGCTATGCCCCTCCCCCAAATCACCCATCACGACTGTGAGGTAAATGCACCTGTGATTGGACGACAGCACCTGCTGCAGGGGGAGGAGCTTCTTTGTGCCTTggatttagttatttaa
>TCONS_00012033
AGGGTGAGTTCAGAGCGAAGGAAGGAGAAATCCAGAGACGCAGCACGTTGTCGGAGAGGAAAAGAGTCTGAGGTGTTTTATGAGCTGTCCAGAGAACTCCCTCTCCCCCACAGCGTCACCTCTAACCTGGATAAAGCATCGGTCATGAGACTGGCTCTCAGTTACCTGCGCCTGCGTAAACTGCTGAACAGCGaTGTGCTGGAGAAGGAGACTGCATTAGACACTCAGTGGAACGGTTCATTTCTGAAAGCTCTGGACGGGTTTCTTTTGGTTCTTTCAGCTGATGGTGATATTGTCTACCTTTCAGAGAATGTCAGCAAGTGCTTGGGCCTTCCTCAGATTGAACTCACTGGTCACAGTGTGTTTGAGTTTACTCATCCGTGTGACCATGAGGAGCTCAGAGAAATGCTGGCACACAGATTTGGTCTGTCTAAGAAATCGAAAGATCAAAACACAAACAGAAGTTTCCTGCTGAGGATGAAATGCacgctgaccagcagagggcgCACTGTCAATGTTAAATCTGCCTCCTGGAAGGTGCTGCGCTGTTCGGGCCGTATCCACACAGCAGATGGTGTTGAGAAGGAGGTGTGTGAAGAAAAAAACACGTGTTCGACGTACCTGGTGCTCATCTGCGAGTCTATTCCCCATCCGGCGAACATTGAGGCTCCTCTGGATTCCAGAACGTTCCTCAGCCGCCACACTTTAGACATGCGCTTCACCTACTGTGATGAGAGGATCACAGAGCTCTTGGGTTTTGATCCAGAGGATGTGTTACAGCATTCTGTGTATGAATACTATCATGCGTTGGATTCAGACCACATGACCAAAACACACCACAGCCTTTTTGTGAAGGGGCAAGTGTGTACCGGACAGTACCGTCTGCTGGCTAAAGCCGGAGGGTTTGTTTGGGCAGAGACTCAGGCCACTGTGATCTATAACAGTAAAAACTCTCAGGCACAGTGTGTGGTTTGTGTCAACTACATCCTCAGTGGCATTGAACAACCCAAACAAATCCTGTCGCTTCAGCAAACCaacagcacaaaaataaaacaggaaGAACACCAGGAGGAGGTTGAGGTGACCATGGCAGAGTTGAAAGAGGAGGAAAAGGAGATGGACAAAGAAGATGAGGAGTGTGTGCAGCCTGTAGTGCAACATAACAGCCTGAAGGGGGAGACAGAGGCGCTGACTGTAGCAGATCCTGTTCTCACGCTGGATATCAACATCACTGACTCAGCGATCTCTGTCCTGACAGAAATTCCTCTCTACAACGATGTCATGTTGCCCTCTTCAGATGTCCTGCTCCCCCTCTCGCCCCTATCTCCCCCGTGCTCCTCTCTAAATGATGATGAAGCCTCCACAGGCCATCTACAACACGACCAATTCCCTTTCCAACAGTCCTCTGACTCCTCCAGATCACAGGTTGATCTACCGGTGGATTCAGAACTatgtgaccagctaaaaccagatcACGTTGAGAAACACTTTTCCATGGATATAGAGTCCAAGACACAGGGAGTGGGTTTGGATCTGGAGATGTTGGCTCCATACATTCCCATGGATGATGACTTCCAGCTGCGGACTGTTTCTCCAGTCAGGCCCATGTGCTCCAGTCCATGTTCAGGGCTTGATCTGACCCCGTCCAGCAGCACACAAACCAGCCCTGCTCTTTCGGCAGCCACTCCAGATTCGCTATCCTGTGATCCCGtgcagcagaaaaacaaaaccaCAGTGCAGGACCACAGCAGAGAAATTATTCAAGACAGTGATATTTCTTATAAATGTCAGACCAACCCGAAGCTACTCAAGAGGAAACTCGAGACCATACCGCTGTCTGAAGCAATAAGACTGGGGTCTGTGCTGCAGGTTGTTACCGATTTTCCAGAGAAAAAGGTCCGCAAAACAGATGCTCCATCATCAGAAGGAATTCGTCATGCTACGATACTGTTGCTGCCATCCAATGTTGCAAGTCGGTTATTGAGCAGATCGTCAGAGGGCGGAGCCATAGCTATGCCCCTCCCCCAAATCACCCATCACGACTGTGAGGTAAATGCACCTGTGATTGGACGACAGCACCTGCTGCAGGGGGAGGAGCTTCTTTGTGCCTTggatttagttatttaaaaaaagccaTACTCATGTTAATTTAACAATTATCAGTGGCATTATGGATGGACTTCCATTCTAAAGAAACAGGGGTG
>TCONS_00012034
GAGCGAAGGAAGGAGAAATCCAGAGACGCAGCACGTTGTCGGAGAGGAAAAGAGTCTGAGGTGTTTTATGAGCTGTCCAGAGAACTCCCTCTCCCCCACAGCGTCACCTCTAACCTGGATAAAGCATCGGTCATGAGACTGGCTCTCAGTTACCTGCGCCTGCGTAAACTGCTGAACAGCGaTGTGCTGGAGAAGGAGACTGCATTAGACACTCAGTGGAACGGTTCATTTCTGAAAGCTCTGGACGGGTTTCTTTTGGTTCTTTCAGCTGATGGTGATATTGTCTACCTTTCAGAGAATGTCAGCAAGTGCTTGGGCCTTCCTCAGATTGAACTCACTGGTCACAGTGTGTTTGAGTTTACTCATCCGTGTGACCATGAGGAGCTCAGAGAAATGCTGGCACACAGATTTGGTCTGTCTAAGAAATCGAAAGATCAAAACACAAACAGAAGTTTCCTGCTGAGGATGAAATGCacgctgaccagcagagggcgCACTGTCAATGTTAAATCTGCCTCCTGGAAGGTGCTGCGCTGTTCGGGCCGTATCCACACAGCAGATGGTGTGTGAAGAAAAAAACACGTGTTCGACGTACCTGGTGCTCATCTGCGAGTCTATTCCCCATCCGGCGAACATTGAGGCTCCTCTGGATTCCAGAACGTTCCTCAGCCGCCACACTTTAGACATGCGCTTCACCTACTGTGATGAGAGGATCACAGAGCTCTTGGGTTTTGATCCAGAGGATGTGTTACAGCATTCTGTGTATGAATACTATCATGCGTTGGATTCAGACCACATGACCAAAACACACCACAGCCTTTTTGTGAAGGGGCAAGTGTGTACCGGACAGTACCGTCTGCTGGCTAAAGCCGGAGGGTTTGTTTGGGCAGAGACTCAGGCCACTGTGATCTATAACAGTAAAAACTCTCAGGCACAGTGTGTGGTTTGTGTCAACTACATCCTCAGTGGCATTGAACAACCCAAACAAATCCTGTCGCTTCAGCAAACCaacagcacaaaaataaaacaggaaGAACACCAGGAGGAGGTTGAGGTGACCATGGCAGAGTTGAAAGAGGAGGAAAAGGAGATGGACAAAGAAGATGAGGAGTGTGTGCAGCCTGTAGTGCAACATAACAGCCTGAAGGGGGAGACAGAGGCGCTGACTGTAGCAGATCCTGTTCTCACGCTGGATATCAACATCACTGACTCAGCGATCTCTGTCCTGACAGAAATTCCTCTCTACAACGATGTCATGTTGCCCTCTTCAGATGTCCTGCTCCCCCTCTCGCCC

Function

symbol description
hif1aa Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including hematopoietic stem cell differentiation; macrophage migration; and regulation of angiogenesis. Predicted to be located in nucleus. Is expressed in several structures, including digestive system; eye; gill; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in carcinoma (multiple); diabetic retinopathy; myocardial infarction; prostate cancer; and type 2 diabetes mellitus. Orthologous to human HIF1A (hypoxia inducible factor 1 subunit alpha).

GO:

id name namespace
GO:1905517 macrophage migration biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0045765 regulation of angiogenesis biological_process
GO:0071456 cellular response to hypoxia biological_process
GO:0005634 nucleus cellular_component
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-080917-55 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including hematopoietic stem cell differentiation; macrophage migration; and regulation of angiogenesis. Predicted to be located in nucleus. Is expressed in several structures, including digestive system; eye; gill; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in carcinoma (multiple); diabetic retinopathy; myocardial infarction; prostate cancer; and type 2 diabetes mellitus. Orthologous to human HIF1A (hypoxia inducible factor 1 subunit alpha).

Ensembl:

ensembl_id ENSDARG00000006181

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012032 False 2154 mRNA 0.49 15 31757331 31783586
TCONS_00012033 False 2204 mRNA 0.49 14 31769809 31783663
TCONS_00012034 True 1294 nonsense_mediated_decay 0.49 10 31769821 31777526

Neighbor

gene id symbol gene type direction distance location
XLOC_006099 prkcha coding upstream 8361 31716820 ~ 31748970 (+)
XLOC_006098 slc38a6 coding upstream 49461 31687973 ~ 31707870 (+)
XLOC_006097 mnat1 coding upstream 75380 31648271 ~ 31681951 (+)
XLOC_006096 six6a coding upstream 151084 31583034 ~ 31606247 (+)
XLOC_006095 ppm1aa coding upstream 177141 31545530 ~ 31580190 (+)
XLOC_006101 NA coding downstream 22857 31806520 ~ 31850508 (+)
XLOC_006102 NA coding downstream 171557 31955220 ~ 31978484 (+)
XLOC_006103 NA coding downstream 321602 32105265 ~ 32108472 (+)
XLOC_006104 osr1 coding downstream 360707 32144370 ~ 32150443 (+)
XLOC_006105 CR769766.1 coding downstream 608720 32392383 ~ 32392499 (+)
XLOC_006074 NA non-coding upstream 828670 30920554 ~ 30928661 (+)
XLOC_006071 CR762493.1 non-coding upstream 920555 30836656 ~ 30836776 (+)
XLOC_006067 NA non-coding upstream 1079688 30676825 ~ 30677643 (+)
XLOC_006065 AL844152.1 non-coding upstream 1245608 30511607 ~ 30511723 (+)
XLOC_006063 AL929330.1 non-coding upstream 1505474 30251741 ~ 30251857 (+)
XLOC_006111 CR936241.1 non-coding downstream 1062830 32846493 ~ 32846609 (+)

Expression


Co-expression Network