| Item | Value |
|---|---|
| gene id | LOC103046962 |
| gene name | ptena,LOC108411875,LOC107670848,LOC101171856,LOC105900832,LOC105940225,LOC104929647,LOC103387686 |
| gene type | misc |
| species | mexican tetra (Astyanax mexicanus) |
| category of species | ornamental fish |
| Item | Value |
|---|---|
| chromosome id | NC_035905.1 |
| NCBI id | CM008308.1 |
| chromosome length | 42966623 |
| location | 12871989 ~ 12912395 (-) |
| genome version | Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome |
| symbol | description |
|---|---|
| ptena | Enables lipid phosphatase activity. Acts upstream of or within several processes, including lifelong otolith mineralization; negative regulation of angiogenesis; and phosphatidylinositol dephosphorylation. Predicted to be located in PML body and cytoplasm. Predicted to be active in several cellular components, including cytosol; nucleus; and plasma membrane. Is expressed in several structures, including nervous system; oocyte; otic vesicle; presumptive neural retina; and ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in several diseases, including Cowden syndrome; breast cancer (multiple); gastrointestinal system cancer (multiple); nervous system cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human PTEN (phosphatase and tensin homolog). |
| description |
|---|
| PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like isoform X1 |
| id | name | namespace |
|---|---|---|
| GO:0046855 | inositol phosphate dephosphorylation | biological_process |
| GO:0046856 | phosphatidylinositol dephosphorylation | biological_process |
| GO:0035335 | peptidyl-tyrosine dephosphorylation | biological_process |
| GO:0001568 | blood vessel development | biological_process |
| GO:0031647 | regulation of protein stability | biological_process |
| GO:0008285 | negative regulation of cell population proliferation | biological_process |
| GO:0051895 | negative regulation of focal adhesion assembly | biological_process |
| GO:0051898 | negative regulation of protein kinase B signaling | biological_process |
| GO:0030336 | negative regulation of cell migration | biological_process |
| GO:0031174 | lifelong otolith mineralization | biological_process |
| GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | molecular_function |
| GO:0030165 | PDZ domain binding | molecular_function |
| GO:0051800 | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | molecular_function |
| GO:0042577 | lipid phosphatase activity | molecular_function |
| GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | molecular_function |
| GO:0004725 | protein tyrosine phosphatase activity | molecular_function |
| GO:0000287 | magnesium ion binding | molecular_function |
| id | description |
|---|---|
| K01110 | PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TU107975 | False | 1884 | TUCP | 0.52 | 8 | 12876039 | 12912380 |
| TU107976 | False | 770 | lncRNA | 0.42 | 2 | 12871990 | 12899172 |
| XM_007244583.3 | True | 3479 | mRNA | 0.49 | 10 | 12871989 | 12912395 |
| XM_007244584.3 | False | 3409 | mRNA | 0.49 | 9 | 12871989 | 12912394 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| LOC103046657 | NA | coding | downstream | 36441 | 12821915 ~ 12835548 (-) |
| LOC103024740 | LOC103024740,LOC108413681 | coding | downstream | 136885 | 12730626 ~ 12735104 (-) |
| yipf4 | yipf4,LOC107744423,LOC107670878,LOC106576945 | coding | downstream | 347152 | 12519463 ~ 12524837 (-) |
| birc6 | NA | coding | downstream | 370705 | 11393761 ~ 12501284 (-) |
| rlf | NA | coding | downstream | 721273 | 12125827 ~ 12150716 (-) |
| LOC103047466 | papss2a,papss2,LOC108411876,LOC105900838,LOC107715960,LOC107583551,LOC107553500,LOC107670849,LOC107689802 | coding | upstream | 9365 | 12921760 ~ 12950947 (-) |
| LOC103025372 | LOC103025372 | coding | upstream | 43975 | 12956370 ~ 12967635 (-) |
| znf593 | znf593 | coding | upstream | 126642 | 13039037 ~ 13048574 (-) |
| LOC103026300 | map4k3,LOC105006890,LOC107715980,LOC107654892,LOC105893436 | coding | upstream | 180336 | 13092731 ~ 13135979 (-) |
| thumpd2 | NA | coding | upstream | 227059 | 13139454 ~ 13150675 (-) |
| G80125 | slc16a12,slc16a12a,LOC107689836,LOC107715954,LOC107744897,LOC107583546 | non-coding | downstream | 53347 | 12818389 ~ 12818642 (-) |
| G80105 | pank1,pank1a,LOC107689800,LOC107553481 | non-coding | downstream | 80402 | 12782613 ~ 12791587 (-) |
| G80060 | NA | non-coding | downstream | 288128 | 12583233 ~ 12583861 (-) |
| G80047 | NA | non-coding | downstream | 328717 | 12540145 ~ 12543272 (-) |
| G79960 | pgrmc2,LOC108438735,LOC107711856,LOC107721516,LOC107654846,LOC107668512 | non-coding | downstream | 497535 | 12223279 ~ 12374454 (-) |
| G80168 | NA | non-coding | upstream | 804 | 12913199 ~ 12975300 (-) |
| G80239 | NA | non-coding | upstream | 106548 | 13018943 ~ 13087370 (-) |
| G80243 | NA | non-coding | upstream | 137368 | 13049763 ~ 13051013 (-) |
| G80253 | NA | non-coding | upstream | 226221 | 13138616 ~ 13138886 (-) |
| G80258 | NA | non-coding | upstream | 233857 | 13146252 ~ 13146698 (-) |
| edaradd | edaradd | other | downstream | 258258 | 12585162 ~ 12613731 (-) |
| ncmap | NA | other | downstream | 499185 | 12334399 ~ 12372804 (-) |
| G79945 | NA | other | downstream | 679961 | 12157586 ~ 12192028 (-) |
| G79865 | NA | other | downstream | 900050 | 11969441 ~ 11971939 (-) |
| ltbp1 | ltbp1 | other | downstream | 1688048 | 10941687 ~ 11183941 (-) |
| selenon | selenon,sepn1 | other | upstream | 108722 | 13021117 ~ 13037306 (-) |
| LOC111193198 | NA | other | upstream | 263641 | 13176036 ~ 13176676 (-) |
| LOC103027799 | rgs7a,LOC108431643,LOC107583631,LOC107668625,LOC107750853,LOC108269497 | other | upstream | 913672 | 13826067 ~ 13919850 (-) |
| LOC111193139 | NA | other | upstream | 1043446 | 13955841 ~ 13956580 (-) |
| LOC103028126 | LOC108431632 | other | upstream | 1056210 | 13968605 ~ 13979750 (-) |