thbs1 (thbs1,LOC108270370,LOC107568499,LOC107687209,LOC107719693,LOC107743901,LOC107678760)


Basic Information

Item Value
gene id thbs1
gene name thbs1,LOC108270370,LOC107568499,LOC107687209,LOC107719693,LOC107743901,LOC107678760
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035905.1
NCBI id CM008308.1
chromosome length 42966623
location 2316627 ~ 2331376 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_015606920.2
TGAAGGGTTTCAGTGAGAACGAGCTGAACTGAGCTGAAACCAGAGGAACCAGGAGGAGGAAAAGCCTTTAAATGGAGAAAACCATCAgagaatattaataattatatttaaagaactatatatttaatcagAGGAGCTGGACTTTaggctttttttattatcacaGATTCTCACAGATTCTTAAACAAAAGGGATTTTAACCAAGACTCTTTTTGTCTGCTGTTCTTTTTTGGGATATCTCATTTTCATTCAGTAAAGAAGTGAAGAAGTTGTGATCATGATGTTCAGCGCGCTCTTTTTACTGCTGATGCTCTGCTGCTGGACTTCAGAAGGAAGCCGGATGGCAGAGAACCGAGATGACAACAGCGTGTACGATCTTTTCGAGCTGGCACGTGTGAATAAGAAGAACCACGGAGTGAGTTTGGTGAAGGGGCCGGAACCCTACAGTCCCGCGTACAAAATCCTCAACCCTAACCTGATCCCCTCCATCCCAGAGCACTCCTTCAGGGACCTCGTCTACTCCATTCAGGAAGAAAAGGGATTCCTCTTCACCGTCAACTTGAAGCAGGCCAAGAAAACCCGAGGCAGCCTCCTGACTGTGGAGAAGAAGGATGGCAGCGGGCCCATTTTCGAGATTATCTCCAACGGAGATGCCAACACTCTGGATTTGGTTTTCACCACGGCTAACAAGCAGGACGTGGTGTCCATCGAGGATGCCCACTTGGCGAGCGGCAGCTGGAAGAACATCACGCTGTTTGTGCAGGAGGATCGTGCGCAGTTACACGTCGGCTGCGAAGAGATTAACACCAGCGAGCTGGACGTGCCTATTCACCAGATTCTGACGCAGGAGGTCGTCGATATCGCTAACCTCAGGATCGGGAAGGGAGCAATGAAAGATAGGTTTATGGGTGTTCTCCAGAATGTGCGCTTTGTATTCAGAACCACAGTGGACGCGATCCGACGCAACATGGGATGCGAGAGCTCCACCTACATCACAGACGTCATGACCCTGGACAACCCTGTGAACGGCTCCAGTCCGGCCATCCGCACTGATTACACTGGACACAAGACAAAagatctCCAAGACATCTGTGGCTTCTCCTGTGAGGACCTGGCCAGCATGTTTAAGGAGCTCAAGGGGCTCGGTGTGGTGGTTAAGCAGCTGTCAAACGAGCTCCTCCAAGTGaGGACGGATAACAACTTGATAAAGAACAAGATCAAAATCCACAGCGGCGTGTGTCTGCACAACGGCGTCGTCTACAAAGACAAGGACGAGTGGACGGTGGACAGCTGCACCCACTGCACCTGCCAGAACTCTGCCACCATTTGCCGGGAAATCTCCTGCCCGCTCATGCCGTGTGCCAACGCCACCGTGCCCGACGGTGAATGCTGCCCACGCTGTGGAACACCGAGTGACTACGCTGAGGACGGATGGTCCCCCTGGTCTGAGTGGACGCACTGCTCGGTAACCTGCGGTCGTGGCATCCAGCAACGCGGACGCTCCTGCGACCGCATCAACAGCAACTGCGAGGGAACCTCTGTGCAAACCAGAGACTGCTACCTGCAGGAATGCGACAAGCGCTTCAGGCAAGATGGCGGCTGGAGCCACTGGTCTCCTTGGTCCTCGTGCTCAGTGACGTGCGGAGAGGGCGTCATCACCCGCATTCGCCTCTGCAACTCGCCTACGCCGCAAATGGGAGGCAGGGACTGCCAGGGAGAGGGTCGTCAAACGGAGCCATGCAAGATGTCTCCATGCCCTGTAAACGGAGGTTGGGGGCCGTGGTCACTGTGGGACACTTGCTCCGTAACTTGTGGAGGAGGACTGCAGACCAGACATCGCCTCTGTAACAATCCCATGCCTAAACATGGTGGAAAAGAGTGCGTGGGTGATGCTAAAGGCACTCGCTTGTGCAACTCCGAGGACTGTCCCATCGATGGCTGTCTCTCCAGCCCTTGCTTTGCTGGAACCAAGTGCACCAGCTTTCCTGACGGCTCCTGGAAGTGTGGCGAGTGTCCTGTTGGGTATACTGGAGATGGCATGCACTGTGAGGACATTGACGAGtGCAAAGCTGTTCCTGAAGCTTGCTTCACTCTTAACGGAGTCCATCGCTGTGAGAACACAGAGCCCGGCTATAACTGCCTTCCGTGTCCCCCTCGCTACTCCGGAGTCCAGCCTTTTGGAAAAGGAATTGAACAGGCGATGGCCAACAAACAGGTCTGCGCACCAAAGAACCCTTGCGAGGATGGCAGCCATGACTGCAACAAAAACGCAAACTGTATTTACCTGGGCGTTTTCTCCGACATCATGTTCCGCTGCGAGTGCAAACCTGGCTACGCAGGAAACGGACACATCTGCGGTGAGGACTCGGACTTGGATGGCTGGCCCAACACCAATCTTCACTGCGTGGAGAATGCCACCTACCACTGCAAGAAGGACAACTGCCCCAACCTTCCCAACTCCGGGCAAGAGGACTACGACAAAGACGGAACCGGAGACGCTTGTGATAGCGATGATGACAACGATGGGATCCCTGATGATAGGGACAACTGCCCGTTCACCTTCAACCCAAGACAGTATGATCAGGACCGCGATGAAGTCGGCGACCGCTGTGACAACTGCCCGTACGACAGCAACCCCGACCAGATCGACACCGACAACAACGGCGAAGGCGATGCTTGTGCCATTGACATCGATGGCGATGGTATTCTGAACGAGAAAGACAACTGCCCATACGTGTACAACATTGACCAGAGAGACACAGACTATGATGGCGTTGGAGACCACTGTGATAACTGCCCGTTGGAGCACAATCCTGATCAGATCGACTCAGATTCAGATAATGTGGGCGACAAGTGCGACAGCAATCAGGACATCGACGAGGACGGCCATCAGAACAATCTGGACAACTGCCCGTACATCCCCAACGCCAACCAGGCCGACCACGACAAGGACGGCAAGGGAGACGCCTGCGACCACGATGACGACAACGACGGTGTTCCTGACGACAAAGACAACTGCAGACTGGCCCCCAACCCAGACCAGATCGACTCTGATGGTGATGGGCGTGGCGATGCCTGCAAAGATGACTTTGACCAAGACAATGTGCCCGATATTGAAGACGTCTGTCCGGAGAACTTCGCCATCAGCGAGACAGACTTCCGCAAGTTCCAGATGGTTCCCCTGGACCCCACAGGAACTTCACAGATTGACCCCAACTGGGTGGTCCGGCATCAGGGCAAAGAGCTTCTCCAGACAGTCAACTGCGACCCTGGCATTGCTGTTGgTTTTGATGAGTTTAACGCCGTGGACTTCAGTGGAACCTTCTTCATCAACACCGACCGTGATGACGATTACGCCGGTTTCGTCTTCGGCTATCAGTCCAGTTCCCGCTTCTACGTGGTGATGTGGAAACAGATCACCCAGACATACTGGTCCACACACCCCACCAGAGCTCAGGGCTATTCTGGACTGTCCATCAAAGTGGTAAACTCCACCACAGGACCCGGAGAGCACCTCAGGAACGCGCTGTGGCACACTGGAGACACGGCAGGACAGGTTCGCACTTTGTGGCACGACCCCAAGAACATCGGCTGGAAGGATTACACTGCCTACAGATGGCACCTGATCCACAGACCTAAAACTGGACACATCAGaGTCATCATGTACGAAGGCAAGAAGGTTATGGCAGATTCTGGAAGCGTATACGACAAGACGTATGCTGGTGGAAGACTTGGACTCTTTGTCTTCTCTCAAGAGATGGTTTACttctcagacctcaaatatgaATGCAGAGataTATAACGGGATCATAGTTTGAGTTCCCCGAAGAATGTGCCGTGAATCATCTTTTGACGTCGACCTATTTATAAGTGCATTACATATTTTCTGGGACGAAGcctttttgagatttttttatttttattatttcctatGATGGGACCAATTGGATGAGATGGAGTCACGTGACCTGGACAGCGGGGACAGCCGAACCCTGCACCAGTGGCAGGTAGAGCACGGACATGCGTGGAGTTCTGCCTGAAACGAGCGAGAAACATTAAGACTTCTGAACTTCTCGACTGGTCAGGTTCATCCTCCCGTCATAGCGgaccaaaaaaagagaaaaggaagcGTTATTGTCTGTAATTGCAGAGCTGAAGCTCAGATCTGCTGTGGACTATAATCTGGAAAGGAAGAAACCTctcataaaaaaatgaagaaaagcaaCAGGAGCTCCACTTCTTTCTGCTGGGTCTGAGGTCCCACTGTGGAGGAACTGTGGGAGAACCGAGGGAGGAGGATGCACAGGacgatatatataaatataaatataaatatatatgtgtgtgtataaacagaaaTGGACTGTCTTTCATGTTGAGAGAATGAATGAgtgtttttgagtgtgtgtgtgtgtgtgtgtgtgtatgtttatgaccaacaccccagttttatGGACTCTTATGTtcatattcttttttattttattttattgtttacaaTGATTACAATGATTTAACCCATCCAGTAACCCATCCAATCAGGTTTCAAGTTTCAAGTTTTATAGTTGATGACAGCATGCCCATTGAAAGGCTATTACTTGCCTTTTTTCTGGAGAtatacagctcagaaaaaaaaatctatttataa

Function

symbol description
thbs1 Enables several functions, including collagen V binding activity; fibrinogen binding activity; and fibroblast growth factor binding activity. Involved in several processes, including regulation of cell migration; regulation of gene expression; and regulation of signal transduction. Acts upstream of or within several processes, including negative regulation of endothelial cell chemotaxis; negative regulation of endothelial cell proliferation; and negative regulation of nitric oxide mediated signal transduction. Located in several cellular components, including external side of plasma membrane; extracellular space; and platelet alpha granule. Part of fibrinogen complex. Colocalizes with collagen-containing extracellular matrix. Implicated in cholangiocarcinoma; pancreatic cancer; and pancreatic ductal carcinoma. Biomarker of COVID-19; cholangiocarcinoma; obesity; pancreatic cancer (multiple); and urinary bladder cancer.

NR:

description
PREDICTED: thrombospondin-1

GO: NA

KEGG:

id description
K16857 THBS1; thrombospondin 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_015606920.2 True 4648 mRNA 0.51 24 2316627 2331376

Neighbor

gene id symbol gene type direction distance location
LOC103039711 NA coding downstream 84195 2221508 ~ 2232432 (-)
LOC103030988 NA coding downstream 182192 2129198 ~ 2134435 (-)
LOC111188180 inf2,LOC103357023,LOC104924786 coding downstream 249602 2061458 ~ 2067025 (-)
LOC103031516 inf2 coding downstream 255490 2047308 ~ 2061137 (-)
adssl1 adssl1,LOC107703625,LOC107678758,LOC107571830 coding downstream 275341 2030382 ~ 2041286 (-)
acp7 acp7,papl coding upstream 100779 2432155 ~ 2457592 (-)
LOC103025843 LOC103025843,LOC108430663 coding upstream 146760 2478136 ~ 2505873 (-)
LOC111193124 LOC108270491,LOC108234815 coding upstream 342040 2673416 ~ 2752256 (-)
LOC103025537 LOC108430628,LOC108269477,LOC107745352,LOC107711907 coding upstream 538120 2869496 ~ 2875636 (-)
LOC103024903 LOC108430667 coding upstream 549733 2881109 ~ 2895681 (-)
G77655 NA non-coding downstream 130764 2183986 ~ 2185863 (-)
G77639 NA non-coding downstream 151680 2127525 ~ 2164947 (-)
G77641 dnajc17 non-coding downstream 170354 2087617 ~ 2146273 (-)
G77630 NA non-coding downstream 288661 2008069 ~ 2027966 (-)
G77626 NA non-coding downstream 375012 1938885 ~ 1941615 (-)
G77683 NA non-coding upstream 28355 2359731 ~ 2359936 (-)
G77684 NA non-coding upstream 61500 2392876 ~ 2393116 (-)
G77695 NA non-coding upstream 117197 2448573 ~ 2469056 (-)
G77696 LOC108430664,LOC108269450,LOC107567345,LOC107678748,LOC104954960,LOC107084056 non-coding upstream 120046 2451422 ~ 2477759 (-)
G77705 NA non-coding upstream 169971 2501347 ~ 2512338 (-)
G77656 NA other downstream 125974 2190313 ~ 2190653 (-)
gchfr gchfr other downstream 161279 2150788 ~ 2155348 (-)
LOC111193168 NA other downstream 269386 2042959 ~ 2047241 (-)
srp14 srp14 other downstream 456218 1853644 ~ 1860409 (-)
LOC103034803 ppp1r14d,LOC105908342,LOC107678771,LOC108269636,LOC101077163 other downstream 552096 1714520 ~ 1764531 (-)
LOC103029757 LOC108430670,LOC108269994 other upstream 632648 2964024 ~ 3044763 (-)
bmf bmf other upstream 844422 3175798 ~ 3206686 (-)
G77892 NA other upstream 966206 3297582 ~ 3348989 (-)
prkd1 prkd1,LOC107590910,LOC107719483,LOC107733145 other upstream 1313721 3645097 ~ 3714357 (-)
G78023 scfd1 other upstream 1503186 3834562 ~ 3840570 (-)

Expression


Co-expression Network