nr3c2 (nr3c2,LOC107598757)


Basic Information

Item Value
gene id nr3c2
gene name nr3c2,LOC107598757
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035921.1
NCBI id CM008324.1
chromosome length 46505145
location 1690077 ~ 1900094 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022684442.1
agagagagcgagcgagacaGACACCTATGCGCGCGCACAGGTAAAAAGGACGCAAGTgcgtttgttgtttttttctgaagccgCGCGCACGAGGAAACTCGCGGACGggattttctctgtttttctggggtttttggtgtttttcttttttttctattcttcttcttcctcctcctctcagcGCGTGATGTGCGCAGCACCGAGCTCAAACTAGTGGacgagcagagagagagagagagagagaggagtacaaacagaagaaaaaggAGAGGAAAACTACTTTCCCTCATTTGGATTAATTGAATAATCGAACGGAGCAACGCGGGGGACGGCGGGGACACACCTGACACAACACCTGGATGACTTAATCAAGGTTTATCAAATGATCCAGGCATGGAGACCAAAAGATACCAAAGTTTCTACGAAGGCACCGACACCGAGAACAGATGGAGCCAGGTGCCAGGATCTATGGAGTACTGCTGCCCAGCAGAGGAGGAGGGTGGCTTGATGAACAGTGATGTCTTGATGGACATTGTGAACGTAAGCAGTGCGTCCAACCCCCCAGCACCAGCGCCCACGTGCAAGGACAGTGTTGCAACAAAGAAGTCAGAGGCACCGATACTTCGGATCGGTCCGAACCAGCCTCTCAGCTTTCCTTCATTTAACAACAACAACTCCCTCCACCATCGCAAGCCAGAAGGCGACTCTAAAGAGCTCTCCAAAACTGTGGCTGAGTCCATGGGCATCTACATGAATGCTGCCCGGGAAGCAGAGTTTGCTTACGGCCAGCAGGGTCCACCCGCCGGGTGCCAGGGCAGCCCTGGCAAACTGTACCCCATGTGTGGCCGAGGGATTGAGGACAAACAGTCCGGAACTGTTGGGAGCCCCAATATGAAAGCTCCACCAACACCATTCCCAACCATGCCTCAACTTCCCAACGGAAACCTTGGGGAGTGTGTTGTAGGCACAGCGTCAACACCTTCTGCCCTGGTCTCGGCTCTGTCCAGCCCTATCGAAAACTCCAGCAACATCTCCAGCCCTACTGGAAACAACATGGTGACTTCCACCACCAGTCCCACCTACTTTGGCGCCAGCTGCCCTTCTATCGGCAGCCCATCAAGCTTGGGGCCAGTTGGTTCAAGCCTAGCTCCAGGCCACCGTCCGAGCTCCAGCACCTGCAGCCCGGTGCAGTCCAGCACAGTTGGGTCTCCACCACTGGCGAGTCCCTTAAACGTGATGAAGTCGCCCATCTCGAGCCCGCAGAGCATGGGAAGCGTGAGGACGCCACCATCCTGCAGCACCAACATAAGATCGTCCGTGTCCAGCCCTACGGGAAGCGGGGGCAAAGTAAGGCCATCCATTTCTAGTCCGCCCACCGTGGGTTCCATGACCATGTCCAGTCCCAGGAACCCTTCTAGGAGCTTCTCCGTCTCAAGCCCTCCCAGCGGTCTGGGTTTGGTGCAAAACGACATCCACAGCCCGGAGGTTCGAGAGCCAGACTTTAAAGGGTTTGAGTTCCCCAAAGTGGAGAGCATTGATGGGGAGATCTTTAACGTAGGTCTGGACTCAATGGGGATGGTCAAGTACATCAAGAACGAGCCGGACACTGATTACAAGAGCATGTGTTTGGGCAGCAGTAAGGCTAACTTGTCCCATTCGCCGTTTGTGGCTCAGATTAAAACTGAACCCAATCAGGACATGACTTGCGGAAGTGCGCACTATGGCGAAACGCAGCACTCCATGGGGCTCTTCCCGGGGTCAGAGACCACATACTTGTCCTTGCGGGATAATTTTGATGAATACAGCCTCTCGGGGATCCTGGGACCTCCCGCTTCTTCTCTTAATGGCAACTACGAGCCTGGCATGTTTCCTAACAATGACCTGCCCAAGGGGATTAAACAGGAGACCAATGATGGCAGCTATTACCAAGAGAATAATAACGTGCCCGCTTCGGCTATTGTCGGCGTTAATTCAGGTGGACATTCATTTCATTACCAGATTGGAGCGCAAGGAACAATGTCGTTTTCACGGCACGACGTGCGGGACCAGACGAACCCCTTGTTGAATCTAATCTCTCCGGTTACGGCGCTAATGGAGACGTGGAAAACACGCCCAGGCCTGTCGCAGTGCCCCCTGTCCGCACGAGCAGACGGCTACACGGGCCCTGGCGGCTTTTCAGACAACATGGCAAGTGCGTCTCTGAGGCACTCGTCCTCCACGGCGAAGGTGTGTCTGGTGTGCGGGGACGAGGCGTCCGGCTGCCACTACGGCGTGGTCACCTGCGGCAGCTGCAAGGTCTTCTTCAAGAGAGCGGTGGAAGgTCAGCACAACTACCTGTGCGCTGGGAGGAACGACTGTATCATTGACAAAATCCGACGGAAAAACTGCCCGGCCTGCCGAGTACGGAAGTGTCTCCAGGCGGGGATGAATCTGGGAGCACGTAAATCGAAGAAGTTGGGGAAGCTGAAGAGTGTGAGCGAGGACTCGGTACAGGGCTCCAAAGACTCCGCCCCGTTCCTCACCTCAGAGAAGGAGCTGACCTCCAGCATGGCTCTGGTTCCTCACGGCTCTGCGGTGACTCCGTACCTGTCGCCGTCCGTCTGCAGCATCCTGGAGCTCATCGAGCCCGAGGTGGTGTTCGCCGGCTACGACAACACGCAGCCCGACACAACCGACCACCTGCTGACCAGCCTCAACAAACTCGCCGGCAAACAGATGATCCGCGTGGTCAAGTGGGCCAAAGTACTTCCAGGTTTCCGCTCTTTGCCCATTGAGGATCAGATCACGCTGATCCAGTACTCCTGGATGTGTCTGTCCTCCTTCTCCCTCAGCTGGAGATCCTACAAACACACCAACGCTCAGATGCTCTACTTCGCCCCGGACCTCGTCTTTAACGAGGAGCGCATGCAGCAGTCGGCGATGTATGAGCTGTGTGTGAGTATGAAGCAGGTCAGTCAGGAGTTCGTCCGGCTGCAGCTCACCTACGAGGAGTTCCTCGCCATGAAGGTTCTGCTGCTCCTcagcacagtGCCCAAAGACGGTCTGAAGAACCACGCGGCGTTCGAGGAGATGAGGGTGAACTACATTAAGGAGCTGAGGCGTTCAGTGGGCAAGGCCACCAACAACTCAGGCCAAACGTGGCAGCGTTTCTTCCAGCTCACCAAGCTACTGGACGCCATGCACGATCTGGTGGGGAACCTGCTGGACTTCTGCTTCTACACCTTCCGCGAGTCCCAGGCTCTGAAGGTGGAGTTCCCCGAGATGCTGGTGGAGATCATCAGCGACCAGATACCAAAGGTGGAGTCGGGCCTGACgcacatcatttactttcacaaGAAGTGACTGGCAGCGGATGAGCAGAAGAAGACAGGAAACTGGGGGTGaatggaagaaagaaagaaagaaagaaagaggggtaAAAGAGAAGATGCGAGGACACCAAGCTCtcggaaaaaaagagagagagcgggaaAAGGTAGAgccagagaaagaaagagagagataaagagagagaagagcccAGGACGGCCAGCTCGCCCGCTATGCACACAGTTAGAGGGATTAATGCTATTGTAAAGCTCAGCTCGCACCGCCggacagagaaaagaaagagagcgaaaaagagaaagagagagaaagaaagagagaaagagcagaggGTAGCATTGTCCGTAGCCAGCCTGCCGAGGAGGACTTCAGCCCGCAGCTCCTCGCCCCCCAAAGACAATGCTGACTATGTTCCTACTATGGATATGAAGCCATATGTTTCTTTGGTAAAGCTATAGTGCACATGTACAAGTGTATAAATAATGctaaagtacacacacacacacacacacacacacacatgtgtacacacacacacacacacacaccgaaacaaagaaagagatagacacAGTAATGTCCTTGCCTCTGAATACCTAAATACAATCTGCATTTAATTACCGAGGCATTTCTGTTTCTATTTAACCGATCCGGACACAACACGTCCACGTTCTTTCagagtacagaaaaaaagagagagagagagagagagaaaaatgcaattaaaagaagaagaaaaaaaaaaacaaatcagaaacGACGTCTTGTTTATATTGTATGTCTGTAGCAATCATACTACTTTCATTACCGGAGGATTTTTGGGGGACAAAAGCCGAGGCACGAGAGGACGTTTTTCCAAGGGCTACACTACCTAAAAAAACCTGAATAGTGTGTCTAATtggtttgtattaaaaaaaaacgcaaaGCAAA

Function

symbol description
nr3c2 Enables steroid hormone binding activity and steroid hormone receptor activity. Acts upstream of or within cellular response to cortisol stimulus and multicellular organismal response to stress. Predicted to be located in nucleus. Is expressed in several structures, including blood; eye; heart; liver; and pleuroperitoneal region. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autosomal dominant pseudohypoaldosteronism type 1 and pseudohypoaldosteronism. Orthologous to human NR3C2 (nuclear receptor subfamily 3 group C member 2).

NR:

description
PREDICTED: mineralocorticoid receptor

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0043401 steroid hormone mediated signaling pathway biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0003707 steroid hormone receptor activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K08555 NR3C2, MR; mineralocorticoid receptor

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022684442.1 True 4257 mRNA 0.53 9 1690077 1900094

Neighbor

gene id symbol gene type direction distance location
tnip2 NA coding upstream 315226 1365801 ~ 1374851 (+)
hmgb2 hmgb2,hmgb2a,LOC100707400,LOC102792727,LOC107752228 coding upstream 1162014 519187 ~ 528063 (+)
hand2 hand2,LOC107676684,LOC107558779,LOC107552491 coding upstream 1221415 465499 ~ 468662 (+)
hpgd hpgd,LOC107552502,LOC107752225,LOC107737128,LOC107676678,LOC107558775 coding upstream 1521017 135827 ~ 169060 (+)
glra3 glra3,LOC107670853,LOC107737127,LOC101174559 coding upstream 1564225 27843 ~ 125852 (+)
prmt9 prmt9 coding downstream 199396 2099490 ~ 2122451 (+)
znf827 znf827 coding downstream 823504 2723598 ~ 2897529 (+)
frem3 frem3,LOC107550584,LOC107654895,LOC107734585 coding downstream 1476757 3376851 ~ 3441060 (+)
LOC103022278 NA coding downstream 1554854 3454948 ~ 3475096 (+)
LOC103021981 NA coding downstream 1579390 3479484 ~ 3499830 (+)
G213142 NA non-coding upstream 86511 1557738 ~ 1603566 (+)
G213137 NA non-coding upstream 179319 1508087 ~ 1510758 (+)
G213073 NA non-coding upstream 327018 1346558 ~ 1363059 (+)
G213061 NA non-coding upstream 337589 1294551 ~ 1352488 (+)
G213060 NA non-coding upstream 341876 1294041 ~ 1348201 (+)
G213166 NA non-coding downstream 6157 1906251 ~ 1928531 (+)
G213235 arhgap10,LOC107742542 non-coding downstream 62149 1962243 ~ 2099280 (+)
G213240 NA non-coding downstream 95753 1995847 ~ 1999106 (+)
G213241 NA non-coding downstream 99869 1999963 ~ 2002593 (+)
G213293 NA non-coding downstream 222929 2123023 ~ 2123277 (+)
LOC103042715 NA other upstream 338681 1340751 ~ 1351396 (+)
scrg1 NA other upstream 1178518 506101 ~ 511559 (+)
fbxo8 fbxo8,LOC107670846,LOC107752227,LOC107676676 other upstream 1440346 229235 ~ 249731 (+)
LOC103044168 NA other downstream 1393834 3293928 ~ 3358194 (+)
G213555 NA other downstream 1788475 3688569 ~ 3688992 (+)
inpp4b inpp4b,LOC107657998 other downstream 2000148 3900242 ~ 4367145 (+)
G213715 znf330 other downstream 2498491 4398585 ~ 4428962 (+)
tbc1d9 tbc1d9,LOC107598515,LOC107594295 other downstream 2610845 4510939 ~ 4590452 (+)

Expression


Co-expression Network