hand2 (hand2,LOC107676684,LOC107558779,LOC107552491)


Basic Information

Item Value
gene id hand2
gene name hand2,LOC107676684,LOC107558779,LOC107552491
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035921.1
NCBI id CM008324.1
chromosome length 46505145
location 465499 ~ 468662 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022684499.1
AAGATGAAGCTGACACCGAGAGCTAAAGAAGATATTCAAGTAGTGCTGCAAGCGTAGAGTGTATGTTTACATGCACGTCCACTGGGATAGGagctttattttgtttgtttactttgtctATCCAGTACTTTGACACTGAATCGAGTTTCACTGCGGATTTGAAAGCCACTTCAAAACTGCAACTTCAAGTTTCTGATGAAGCTTCCAGCTCGCAGTGATCACTAATGGAGTTTTTTCATGGTGGATATGGACAATGGAGCACATAGGCGTATGTAAGtagttgttttccagtgttttccAGCTTTCCGAACCACGTTTTGGGGGTCAGTTTTGGGTGCTTCTGCTTCAAGTATGCGTCCATGAATAGCATTGCTAGTTTACTGATGGACCAGTAGGACGGTGTTGGCGCTTTGACTCACTAGAAAAGTTCTACACGGCTTCCTGTCCATGGGAGTGCAGTGAGAACCTCAACACGACCAGACCAACCAAAAAATAACCAAGAAAATCAGAACTTTACAGTGGTTCTTCAGTTTTAAATCAGTCGCGATGAGTTTAGTTGGAGGCTTTCCCCACCACCCTGTTATGCACCATGACGGCTACTCCTTCGCCCCGGCCACCCGCTGTCACGAGGAGAGCCCTTATTTTCACGGTTGGCTCATCGGTCACCCGGAGATGTCCCCCCCGGACTACGCCGTGGCTCCCTCGTACAGCCCCGAGTACGCGGCCGGCCCACCGGGGCTCGAACATTACGGCGGCGGGGTTCCCGGGACGGCGCCGCGGCCGGGCAAACCCCGGAGGCCCACGGCCAACCGCAAGGAGAGGCGCAGGACTCAGAGCATCAACAGCGCCTTCGCCGAGCTCAGGGAGTGCATCCCCAACGTGCCTGCAGACACCAAGCTGTCCAAAATTAAGACGCTGCGACTGGCTACCAGCTACATCGCCTACCTCACTGACATCCTAGACAGGGACGAACAGCACGGCGAGGCCGAGGCCTTCAAGGCGGAATTCAAGAAGGCTGAAGCcaaagaggagaggaggaagaaagaaatgAATGAAGTTTTGAAAAGTTCAGGGAGCAGCAGTGAAAAGAAGCCCAAAGGAAGAACTGGTTGGCCTCAACACGTCTGGGCTTTGGAACTGAAACAATGAGAACACAAGTCCGCAAAAAACCCAGAAACCGTTTACGAAAAGACCTTGAAATGCAGGCCTTCCTGTCCCTctgattttttacactataactTTATTTAATGGAATATTTATGTGCAATTTCCCGCTCCGGACAGTGGATCcctgaagagaaaaaaacattgcagaGCTTTAAGAGGAGGATGCCCTCTTGGTAAGGGactctgttgttgttgttatcgTTGTTACTGTTGTTGTCTAGTATGTgctgaatgttttattttattattttttttattttgtccatGTCTCACTCTGAAACAAAACCGAGATGTGTGCCACTAAGGTGTACGTGAAGTGTaggtctctctcttactctctctctctctctctctctctctctctctctctgagtcgaATTAAACACTAAGGGGATCGAATCTATGATACAGTTAAAATAATAACGTTttatttgaaacaaaaaaaaatgtcatgaagtgttaaatatattgtgatgtttGTGGTCGTGTAGATCCAAGTGCACTTCCGTCCAGACACGAGAACCTTAAATAACATTGGAGATGTAAAcaatgtaattaattcaataaaCCACTGTGTTTTAACGAG

Function

symbol description
hand2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including animal organ development; determination of intestine left/right asymmetry; and nervous system development. Predicted to be located in nucleus. Is expressed in several structures, including cardiovascular system; digestive system; head; mesoderm; and pectoral fin. Orthologous to human HAND2 (heart and neural crest derivatives expressed 2).

NR:

description
heart- and neural crest derivatives-expressed protein 2

GO:

id name namespace
GO:0003342 proepicardium development biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0003142 cardiogenic plate morphogenesis biological_process
GO:0003144 embryonic heart tube formation biological_process
GO:0071908 determination of intestine left/right asymmetry biological_process
GO:0035118 embryonic pectoral fin morphogenesis biological_process
GO:0030859 polarized epithelial cell differentiation biological_process
GO:0010002 cardioblast differentiation biological_process
GO:0030878 thyroid gland development biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0060047 heart contraction biological_process
GO:0005634 nucleus cellular_component
GO:0003677 DNA binding molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG:

id description
K18486 HAND2; heart-and neural crest derivatives-expressed protein 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022684499.1 True 1752 mRNA 0.47 2 465499 468662

Neighbor

gene id symbol gene type direction distance location
hpgd hpgd,LOC107552502,LOC107752225,LOC107737128,LOC107676678,LOC107558775 coding upstream 296439 135827 ~ 169060 (+)
glra3 glra3,LOC107670853,LOC107737127,LOC101174559 coding upstream 339647 27843 ~ 125852 (+)
hmgb2 hmgb2,hmgb2a,LOC100707400,LOC102792727,LOC107752228 coding downstream 50525 519187 ~ 528063 (+)
tnip2 NA coding downstream 897139 1365801 ~ 1374851 (+)
nr3c2 nr3c2,LOC107598757 coding downstream 1221415 1690077 ~ 1900094 (+)
prmt9 prmt9 coding downstream 1630828 2099490 ~ 2122451 (+)
znf827 znf827 coding downstream 2254936 2723598 ~ 2897529 (+)
G212921 NA non-coding upstream 110035 355052 ~ 355464 (+)
G212920 NA non-coding upstream 117666 347539 ~ 347833 (+)
G212919 NA non-coding upstream 123990 341307 ~ 341509 (+)
G212871 NA non-coding upstream 207907 254024 ~ 257592 (+)
G212872 NA non-coding upstream 212121 251844 ~ 253378 (+)
LOC111195947 NA non-coding downstream 7762 476424 ~ 488543 (+)
G212940 galnt7,LOC107737119,LOC107551995 non-coding downstream 74818 543480 ~ 544402 (+)
G212945 NA non-coding downstream 111186 579848 ~ 581109 (+)
LOC111195934 NA non-coding downstream 118953 587615 ~ 592952 (+)
G213013 NA non-coding downstream 477303 945965 ~ 946193 (+)
fbxo8 fbxo8,LOC107670846,LOC107752227,LOC107676676 other upstream 215768 229235 ~ 249731 (+)
scrg1 NA other downstream 37439 506101 ~ 511559 (+)
LOC103042715 NA other downstream 872089 1340751 ~ 1351396 (+)
LOC103044168 NA other downstream 2825266 3293928 ~ 3358194 (+)
G213555 NA other downstream 3219907 3688569 ~ 3688992 (+)
inpp4b inpp4b,LOC107657998 other downstream 3431580 3900242 ~ 4367145 (+)

Expression


Co-expression Network