mthfd1l (mthfd1l,si:ch211-266i18.6,LOC107665399)


Basic Information

Item Value
gene id mthfd1l
gene name mthfd1l,si:ch211-266i18.6,LOC107665399
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035899.1
NCBI id CM008302.1
chromosome length 74127438
location 56055205 ~ 56125560 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022663154.1
GCAGCGGTTATCGTGTCTCAGCGTGTCGTGTGGGCTGGCTGGGAGTGAGAGAGACTCTCAGAGTGAGGCAGCCGCTCACTCTTTACCCTCCGCCGCCCTGCAGTTCACACCATGAGGCTGTCCGCCGCTCTCCGACACGCCTGCCGGACCAGCCGGTCTGGAGCCGGCCAGGTGAGGGTGCTCAGCCCGCGGGGGAGCTCCACAGCCCGCGAGGAGAGGAGCGCGGGCTGGGCGCCGGTCAGAGGGACCCACTACACCTCCGGCAGCAGCGGCGGGAGCTCCGCTCACTCCCTCAGCCTGCAGAGCCGCAGCCCCCGGCTCAGGGCGGAGCACCAACACGCCGCCAGGGAGATCATCGAGAAGAGCAGAGAGGAGCTGGCTTCTGTGCTTAAAGCCCATCCAGCCATTAAACCCACACTGGCCATCATACAGGCTGGAGAAGATGACATTCTGCTGGAGATGAATACGATGATGGCTGAAAAGGTTGGCCTGAATGTGATGCAAATATGTCTGCCACGCCACTGCACTGAGGAGGAGGTCATAGAGGAGGTTCTGCGTCTAAATGAGGACCAGAATGTTCATGGTGTGTTCCTGTGTCTTCCTCCATCCATCCTCTCCCGGAGAATACTCAacaccatcaaacctgagaaagacGTAGATGGGGTTTCAGATTTGAACGTGGGGCGCCTGGTTTCTGGAGCTCTATCAGAAGGGTTTCCCTCACCTGTAGCAGGAGCTGTGCTAGAACTGCTGTCCAGACAGGATGCTTCACTGGCTGGGAAAAGGGCAGTGCTGGTTGGCCTAGAAGGGCCTCTGAAGGTGATCCTCCAGTACCTCCTGCAGGATGCTGGAATGGAAGTGCAGACCAGCCGATGGGCCGCAGACAATCTACAGAAGCAGgtcAAGCAAGTCGATGTAGTTGTGGTGATGGGGACTGAAAACACTGATCTGCTACCTATCTCAGTCAAGCCAGGAGTAACAGTCATTAACTGTGGTTCTGccttaatgccagAGATCTCAGCTGCtgaggagagagcgagagaagctGAATGCTGGACTGAGATTGGCCCGATAAGTGCTGCCTTAAGGATGCAGAATGTGGTGAGGAGCAGTGTGAGATGGGTAGAGAATCAGCAGTATCAGACATGGACACTCCGCCCCCTGAAGCTCCAGCCACTGTCTCCTGTGCCTAGTGATATCGAGATCTCCAGAGCTCAAACCCCAAAACCCATAGTGCAGCTGGCTGAGGAGATTGGCCTGCTGCCGGAGGAACTGGAGGCTTATGGGCGCACCAAGGCCAAGGTCCGCCTCTCTCTGCTCACACGCTTGCAGAACCAGCCCAATGGCAAATACGTCCTGGTGGCAGGCATCACTCCTACACCTCTTGGAGAAGGCAAAAGCACTGTGACCATTGGTCTGGTCCAGGCACTTTCTGCTCACCTCAAGCTCAACTCCTTCGCTTGCTTGAGACAGCCGTCTCAAGGTCCCACATTTGGAGTCAaagGAGGGGCTGCAGGAGGGGGCTATGCGCAAGTCATTCCCATGGAAGAGTTTAATCTTCACCTCACTGGTGATATCCATGCCATAACAGCAGCCAACAACCTTGTGGCAGCAGCAGTTGATGCCCGCATCCTGCATGAAGCTACACAGTCAGACAAGGCTTTATACAACAGACTAGTGCCTTCTGTGAATGGAGTGAGACGCTTTTCTCCCATCCAGCTGGGCAGACTGCAGCGTCTTGGAATCAACAAATCTGATCCCGGCACCCTCACGCCAGAGGAGGTCCGCTCCTTTGTCCGCCTTGACCTTGACCCAGCAAAAGTCACTTGGCAGAGAGTGGTAGACACCAACGACCGTTTCCTGCGGAAGATCACAGTCGGCCAGGCAAACACAGAGAAAGGCCACAGCCGACAGACACAGTTTGACATTGCAGTGGCCAGTGAGATCATGGCTATCCTGGCCTTAACTGATGGGCTGGCTGACATGAAGTCCAGGCTTGGCCGCATGGTAGTAGGGAGCAGTCGGAGTGGACAGCCAGTTACTGCAGATGACCTGGGTGTGACTGGTGCTCTCGCAGTGCTGATGAAAGATGCCATCAAACCCACCCTGATGCAAACGCTGGAGGGCACACCAGTGTTTGTGCATGCTGGACCATTCGCCAACATTGCCCATGGCAACTCCTCTGTTCTGGCAGACCAACTTGCTCTTAAACTGGTTGGAGAGGACGGCTTTGTGGTAACTGAGGCAGGTTTCGGAGCTGACATTGGTATGGAGAAGTTCTTCAACATCAAGTGTCGTGCTTCTGGACTAAAGCCTGATGTTGTGGTGTTGGTTGCCACCATCAGAGCACTGAAGATGCATGGAGGAGGTCCCAGTGTAACAGCAGGGGCGCCATTGCCGAAAGAATACATTGATGAGAATCTACAGCTGGTTTCTGAGGGCTGCAGTAATCTGAAGAAGCAGATTGAGATCGCCCGTCTGTTTGGAGTTCCGGTGGTGGTGGCTCTTAACGTCTTTAAGACTGACACAGAGGCGGAGGTTGACCTTGTGTGCCGCATCGCAGAGGCTTCTGGGGCATCAGCTGCTGTGCCGTGTCATCACTGGACCCGCGGTGGGCGGGGCTCTGTGGAGCTGGCTCGCGCTGTCAAGGAAACTGCAGCACAGGAGAATGATTTTCACTTCCTCTACAGCTTGCAGACGCCTATAGTGGAGAAAATTCGCACAATCGCACAGAAGGTTTATGGAGCCGACGACATTGAGTTGTCGCCTGAAGCCCAAGCTAAGATTGAATATTACAATCAACAGGGCTTTGACACCCTGCCGGTTTGCATGGCCAAGACCCACTTGTCACTCTCTCACATGCCTGACAAGAAGGGTGTGCCCACTGGTTTCATTCTGCCAATCAGAGATGTCCGAGCCAGCATTGGGGCGGGGTTTATCTACCCACTGGTTGGAACAATGAGCACCATGCCAGGCCTGCCCACGAGACCCTGTTTCTATGACATCGACCTTGATCCAAATACCGAGGAGATAACCGGGCTGTTCTGAGCTTCCTGGCAGAAAGATTCAGAAAGTCACGTCGTCAAATTTCGTCCAGGCAGACAGTTCAAGTGACTTCTATTAAACCTACAGCCTTCAGCCCTATGGCACCAGATACCAATTCCCTATCAGATGAATCagaagagctttttttttgcattcatgATGCACACATTGTTTGGAAACCAATTATGCGCACAATGAAATGAAGAttaatttaaaatctttttattatttttttgaccAAACTTTTACTATGTATGCGAGAAAATAGTTAACTCCAGTTAATGCAATTTAAGTTTTatcaactttttttaagttcttttttAAGTTCTGTTAGTAAGTTTTCTGTGAACAGTCTGAATGTTACTGTAGAAGAGTAATTATAGTGTTATGTGTTTATGATTTttgaaatgtaagaaatgttcaTTCTTACCGGGCAAAGCATTTCagtgtaattcaTAGTGTCAAGATCTAATTTTATCCTCAGCCTTTTGAAAACTGCCAAttctctgtatttttatataacttAGCATTAaccagttgtttttttatgttgttatgttttttcttcCTGTGAACTGTATTACGCACAATGCCTCACAGGCAAGTCTTTACACTTCCTAACAGCAGTGCCAAAATAATtgatatcttaatatcttaatcGCTGTGTGAactatgtttattaataaacaaataaagttgACTAAAGAGTTGCTTTTATTTACCCCTCAA

Function

symbol description
si:ch211-266i18.6 Predicted to enable ATP binding activity; formate-tetrahydrofolate ligase activity; and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to act upstream of or within one-carbon metabolic process.
mthfd1l Predicted to enable methenyltetrahydrofolate cyclohydrolase activity and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in tetrahydrofolate interconversion. Predicted to act upstream of or within one-carbon metabolic process. Predicted to be active in cytosol. Is expressed in anterior neural tube and optic cup. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human MTHFD1L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like).

NR:

description
monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X2

GO:

id name namespace
GO:0009396 folic acid-containing compound biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004329 formate-tetrahydrofolate ligase activity molecular_function

KEGG:

id description
K13402 MTHFD1L; monofunctional C1-tetrahydrofolate synthase, mitochondrial

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022663154.1 True 3774 mRNA 0.51 29 56055205 56125560

Neighbor

gene id symbol gene type direction distance location
LOC103043128 NA coding downstream 11920 55949627 ~ 56043285 (-)
armt1 armt1 coding downstream 124019 55924510 ~ 55931186 (-)
LOC103043741 LOC108424497 coding downstream 135959 55889634 ~ 55919246 (-)
LOC103044058 LOC108424438 coding downstream 396073 55654005 ~ 55659132 (-)
serac1 serac1,LOC107555766 coding downstream 402812 55640884 ~ 55652393 (-)
gpr176 gpr176 coding upstream 28154 56153714 ~ 56170803 (-)
LOC103032431 LOC108424505 coding upstream 47897 56173457 ~ 56187855 (-)
LOC103029201 LOC103029201 coding upstream 115411 56240971 ~ 56252577 (-)
LOC103033540 fntb,LOC108424508,LOC107668263,LOC107756604,LOC107721314,LOC107671778,LOC103359368 coding upstream 148926 56274486 ~ 56289838 (-)
zfyve1 zfyve1,LOC107721321 coding upstream 587057 56712617 ~ 56723774 (-)
G28567 NA non-coding downstream 160366 55894509 ~ 55894839 (-)
G28568 NA non-coding downstream 165102 55886323 ~ 55890103 (-)
G28505 NA non-coding downstream 418545 55635525 ~ 55636660 (-)
G28395 NA non-coding downstream 629556 55424296 ~ 55425649 (-)
G28394 parp1,LOC107678834 non-coding downstream 631462 55418687 ~ 55423743 (-)
G28604 NA non-coding upstream 597 56126157 ~ 56126524 (-)
G28606 NA non-coding upstream 3635 56129195 ~ 56129732 (-)
G28617 NA non-coding upstream 21616 56147176 ~ 56147738 (-)
G28634 NA non-coding upstream 64929 56190489 ~ 56190689 (-)
G28661 NA non-coding upstream 88984 56214544 ~ 56227854 (-)
G28536 NA other downstream 238607 55815872 ~ 55816598 (-)
gtf2h5 gtf2h5,tf2h5,LOC107721375,LOC107659223 other downstream 413830 55634532 ~ 55641375 (-)
G28501 nrbp1,LOC103372645,LOC105015343,LOC106537236,LOC102314540 other downstream 448319 55602870 ~ 55606886 (-)
LOC111189318 NA other downstream 553445 55499900 ~ 55501760 (-)
mixl1 lin9,LOC107678835,LOC107726751,LOC107697095 other downstream 610536 55432081 ~ 55444669 (-)
LOC103031416 dpf3,LOC108424513,LOC107659173,LOC107721322,LOC107668213,LOC108257599,LOC107562702,LOC107602065 other upstream 514791 56640351 ~ 56694835 (-)
ppp4r4 ppp4r4,LOC107711657 other upstream 1686702 57812262 ~ 57841318 (-)
LOC103041090 LOC103041090,LOC108424449 other upstream 1866081 57991641 ~ 57995476 (-)
LOC111189852 LOC108411318,LOC108257913,LOC107721335,LOC102302990,LOC102081001 other upstream 2033647 58159207 ~ 58174704 (-)
G29317 eif5,LOC103022293,LOC107561927,LOC107746071,LOC108435020,LOC107589079,LOC107701513,LOC107582488 other upstream 2807403 58932963 ~ 58934789 (-)

Expression


Co-expression Network