CI01000013_08555865_08573521 (FGD4, FGD4A)


Basic Information

Item Value
gene id CI01000013_08555865_08573521
gene name FGD4, FGD4A
gene type misc
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000013
NCBI id null
chromosome length 12551977
location 8555208 ~ 8573521 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000013_08555865_08573521.mRNA
CTGTTGGCAGCAGCAGTCCTGATGAGCAAGGTTGTCACAATGAGAAGTTGAATCGTGGATGCAGATTCAGCAATAAGGGCCTTACTGGAGTAAATGGAAGAGTTTCAGGCCGACGGCCACCACTGCAACCCAAACCACAAGTGCCTCCTAAACCTGCACACCTTCAGAGTCCGGTGACGGAAGTTTCCTTTCCTCTGGCTGCCGGAAAGTTATCCATCAATCCCAGCATGGAGGGGGGAGGAGTAGGAGGAGCAGTAGGGAAGGGCCGAGTGTCCAACCTCATCAGTCGCTTTGAGGAGAACCGTCACACAGACGGTCGGAGGGAGGGCGCTCCTCTGAAGCAGGTCAGCAGATCTCCTAACTCCAGCCCGCCTCATAAGAGCTACCAGAGACAGACGGAGCAGCCCACAGACTCCGGCTCTGGCGCGACCAGCCCACGCCATGCTCTCAAACCCCCCAATGGGGTTCTAGCACAGAAGAACAGAGACCAGGACAGAGATCTGGACATGGATGGCGTTAAAAACGATACAGTTCCGGTCGTGAGGATAGACACGCAGGACTTGCTGAACGGAGATGCCGCCGATATGGCTAAGAGGGCAATTATGGACGAGGACTCGGTAGATATGCCTCATGCTCACATAGACCAGGTCGAAGAGCAGGAGAGGAAAGCACCAGAGCAGCATGATGTTGTAATGAACAGCATCCCCGAGCAGAAGTGTGCATCAGGAAGTTCCTTTAACAGACTTCAGCGTGTACAGTGTGTGTATGCCAGTAGATGTTCATTTGTGTATGGGTGTGATAGAGAGAAAGAGGGGAAGAAATGTTATGGTGAGGAAACCAATGAGCAGAAGCTCTACAAGATAGCAAATGAACTTCTGCAGACAGAGAAGGCCTATGTTGCACGACTCAACTTATTAGATAAGGTGTTTTATGCCAAGCTGATAGAAGAGGCAAGAAAAGACACATTCCCCGTGGATGTGGTGATGAAAATCTTTTCCAACATCTCTTCCATTAATGCCTTCCACAGCCAGTTCCTTCTGCCTGACCTGGAAAAACGCATGGGAGAATGGACGTCAACACCTCGCATTGGTGACATCCTACAGAAGCTCACGCCCTTCTTGAAGATGTACGCTGAGTATGTGAAGAACTTTGATCATGCCTTGGATCTGCTGAAGCAATGGACAGATCGATCACCTCCATTTAAAGCTATCATTCTGGAAATCCAGAGTCAAGAAGTGTGTGGCAGTCTGACGCTGCAGAACCACATGTTGGAGCCTGTTCAGAGAGTGCCACGATACGAGATGCTGCTCAAAGACTATCTGAAGAAACTTCCTCAGGATCACATAGACCGGCGGGATGCTGAAAAGTCTTTAGAGATTATTTCCATGGCTGCCACTCATTCCAACACTGCCATTAAGAAAACAGAAAACCTTAAGAAATTGCTGGAAATTTATGAGATGTTGGGAGAAGAAGAGGACATCGTGAACCCCTCGAATGAGTTGATAAAGGAGGGTCATATTCTAAAACTGGCAGCCAGAAACACTTCAGCCATGGACAGATATCTCTTCCTGTTCAACAACATGCTGCTGTACTGCGTTCCCAAGTTCAGCTTGGTGGGACAGAAGTATACAGTGCGCACACGTATTGGCATTGAAGGCATGAAGGTGATGGAGACGTACAATGAGGATTATCCTCACACCTTTCAGGTTTCCGGAAAGGAACGGACACTGGAGCTGCAGGCCAGCTCCGAACAGGATAAAAAAAGCTGGATAAAGGCATTCCAGGAAACGATACACATCTCCCTCCAGAAAAATGAGACCTTTAAGTCAGCATTCAAAGATGCGGAGGAAGCATCGGAGCTTAAGATATCAGAGCTGGGTAAAAGAGCCCCTCGCTGGATCCGAGACAACGAGGTGACCATGTGCATGAAGTGCAAAGAGGCCTTTAATGCTATCAGACGCAGGAGACATCACTGTCGGGCCTGTGGTTACGTGGTCTGCTGGAAGTGCTCAGACTACAAAGCCATTCTGGAATATGATGGGAATAAGATGAACAAGGTGTGCAAAGACTGTTACTCGATCCTGACAGGCCATATAGACAGTGAGGAGAGGGAGGGCAAGAAGAAGGGCATTCTAGAGATTGAAGCTGCTCAGTTCTCAGGCAACAGTATCATGTGTGGCTTCCTACAGTACTGTGAGAAGAACAAGCCCTGGCAGAAAGTCTGGTGTGTTATTCCTCAGAAGGAAGCTTTAGTTCTCTACTTGTACGGAGCACCTCAGGATGTCAAGGCCCAGTCCACAATTCCTCTGCTCGGCTACCAGGTGGAGGACAACCCAAGACCCACCGACCCTCCTGCAAGCTTCAGACTATCTCAGTCTAAATCAGTACACAGCTTTGTCGCAGAAAGCGAGGAACTGAAACAGCGCTGGCTCAAAGTGATCCGTATGGCGGTGACGGGAGAGGAACCAGAATCGCCTGAAGAAAGCCATTCTACGGAAATCACCCAAGAAACAAACTCTAACGGTGTCTAAGCAAAGAGAGCGTACTTTTCTTAAAGATTTCTCTACAGATGTGGCGATGCAATTGGTAAGAAAAGTGTTGACACTCCTCCTGCTTACGTTGCACAGACTTGCTGCGCCATTACTGCTGGACTGTCTGAGCTACAGCATTTGTCCAGTTGTCCTAAAGTTCCATTTGGATTTGAACACATCCAGAATATGGGGGTTGAAAGGACATGGACATCAGCTTGACCTTTACCGGACAGATTTGAAGTTCATACAAATGGAGCTCATGTGAAGAGTACTAAGAGATGCTATTCCATCATCACACCTTACTACAGCTGATGCCGCACTGTTTCAAGCCTAATGTAAATATTGTACAACTATTGTACAAAATATTGAACATTTACATGTTGTATGTATAGTATATTGAGGCTAAAATTCAGATGTGTTGACAGCATTGTAAAAAATGTGATGTGTATGTGCAGGACATAAGCGCTTTTCAAAAAGTCAAGATTGCAATCTACTGCAACTATAAATTGCATTCAGTTCCAGAACGCTCTGGATGCAATAGACACTCCTTCATTATGGCCATCGTGACTTTGCCAAGACAGACATGTTGTGTTGACACATTTGTTGATCCTAGGGTTGCAGCGGTATACTGGTTTCACGATATATCATTGTATTAAA

Function

symbol description
fgd4a Predicted to enable guanyl-nucleotide exchange factor activity and metal ion binding activity. Predicted to be involved in cytoskeleton organization and filopodium assembly. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. Is expressed in basal plate midbrain region; diencephalon; and tegmentum. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4H. Orthologous to human FGD4 (FYVE, RhoGEF and PH domain containing 4).
fgd4 Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Predicted to act upstream of or within lamellipodium assembly; microspike assembly; and positive regulation of JUN kinase activity. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Predicted to be active in cytoplasm. Implicated in Charcot-Marie-Tooth disease type 4H.

GO:      GO:0005089, GO:0046872, GO:0035023

KEGG:

id description
K05723 FGD4; FYVE, RhoGEF and PH domain containing 4

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000013_08555865_08573521.mRNA False 3188 mRNA 0.47 17 8555208 8573521

Neighbor

gene id symbol gene type direction distance location
CI01000013_08418098_08441411 NA coding downstream 113457 8417837 ~ 8441751 (-)
CI01000013_08311120_08328130 NA coding downstream 226865 8310985 ~ 8328343 (-)
CI01000013_08308180_08308362 NA coding downstream 245295 8307851 ~ 8309913 (-)
CI01000013_08229647_08258878 TBXAS1 coding downstream 296330 8229172 ~ 8258878 (-)
CI01000013_08098898_08099508 UQCRFS1 coding downstream 455700 8098758 ~ 8099508 (-)
CI01000013_08616374_08648611 BICD1A, BICD1 coding upstream 42683 8616204 ~ 8648611 (-)
CI01000013_08732651_08797549 TMTC2 coding upstream 159130 8732651 ~ 8797549 (-)
CI01000013_08950324_08962808 NA coding upstream 376457 8949978 ~ 8962808 (-)
CI01000013_09007324_09008538 NA coding upstream 433736 9007257 ~ 9008749 (-)
CI01000013_09293519_09305846 TTC38 coding upstream 719612 9293133 ~ 9305846 (-)
G83634 NA non-coding downstream 1965 8551722 ~ 8553243 (-)
G83631 NA non-coding downstream 5359 8545354 ~ 8549849 (-)
G83636 NA non-coding downstream 13290 8539931 ~ 8541918 (-)
G83633 NA non-coding downstream 19183 8531160 ~ 8536025 (-)
G83677 NA non-coding downstream 25840 8529152 ~ 8529368 (-)
G83692 NA non-coding upstream 88080 8661601 ~ 8661813 (-)
G83695 NA non-coding upstream 92084 8665605 ~ 8665808 (-)
G83699 NA non-coding upstream 95474 8668995 ~ 8669251 (-)
G83702 NA non-coding upstream 104370 8677891 ~ 8678105 (-)
G83706 NA non-coding upstream 111365 8684886 ~ 8685095 (-)
CI01000013_07339918_07367774 NA other downstream 1172848 7339709 ~ 7367774 (-)
CI01000013_05883498_05884071 CHTF8 other downstream 2670836 5882049 ~ 5884071 (-)
G81547 NA other downstream 2811170 5739526 ~ 5744038 (-)
G81032 NA other downstream 3804647 4748809 ~ 4750561 (-)
CI01000013_04561253_04567647 MAP2K1 other downstream 3996305 4560340 ~ 4567647 (-)
CI01000013_09309438_09335834 MICAL3A other upstream 733515 9307036 ~ 9336077 (-)
G85170 NA other upstream 1906340 10479861 ~ 10480700 (-)
CI01000013_10564288_10569141 NA other upstream 1989938 10563459 ~ 10569290 (-)
G85188 NA other upstream 2018683 10592204 ~ 10595337 (-)
G85401 NA other upstream 2461511 11035032 ~ 11035466 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_012647 fgd4a coding NC_007129.7 CM002902.2 12147971 ~ 12229524 (+)