CI01000015_00690873_00738349 (KCNH1, KCNH1B)


Basic Information

Item Value
gene id CI01000015_00690873_00738349
gene name KCNH1, KCNH1B
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000015
NCBI id null
chromosome length 8631711
location 690478 ~ 739716 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000015_00690873_00738349.mRNA
GTATATATGAGTAGGATTTTATAGTGTTTTTATAACATCAGAACAAACATAATAGGGTTACAGTAACTTGGGTGTTTGGACCATAGGGTTTGGACTCCTAATCACTAAAGAAATCTGACCTCACCTCAGGTTTTGCTTATTCTGTAGTTCTCCCTCTCACCAACAGATGTCTCCGTCGATCACTGATTGTCAGACTCAGCATATGCTGGATCTCTTTACACAGATGTTGTCTATAGAAGACTCTGGTTGGCTCTTCAACAGCAGGGGGAGGCACAAGCAGCCAGTGCTTTATATCCTGATTTGGGCTCTTAACTCTGGCCATAATCATGTAGGCTGCTTTCAGGCAGGAGCCAGCCTCATCCTCACACTGATCTCAGACCGCATGAGGAGTAGGGATGGCCGGGGGACGCAGAGGACTGGTGGCCCCTCAGAACACTTTTCTGGAGAATATAGTCCGTCGCTCCAATGACACCAATTTTGTTTTGGGGAATGCCCAAATTGTGGACTGGCCTATTGTCTACAGCAATGATGGATTCTGCAAGCTGTCTGGTTACCATCGTGCTGAAGTCATGCAGAAGAGCAGCACATGCAGCTTCATGTATGGGGAACTCACTGACAAAGAAACCTGCGAGAAAGTCCGCCAGACCTTTGAGAACTATGAGATGAACTCCTTTGAAATACTCATGTACAAGAAGAACCGGATGCCAGTGTGGTTCTTCATTAAAATTGCTCCCATCCGAAACGAACAGGACAAAGTTGTACTTTTTCTCTGCACCTTCAGTGATATCACTGCATTCAAGCAGCCTATTGAAGATGACTCATCTAAAGGCTGGGGTAAGTTTGCTCGCCTGACACGGGCGCTGACCAGCAGCCGTGGTGTTTTACAGCAGCTGGCGCCGACTGTCCACAAGGGCGAGAACGTCCACAAGCACTCCCGTCTGGCTGAGATTGTAGTTATACTCTGTCCTCTTCTTATTCCCTATCAGGTACTGCAGCTAGGCTCGGACATCCTCCCGCAATACAAGCAAGAGGCTCCGAAAACGCCTCCTCACATCATCCTGCATTACTGCACCTTCAAAACTACCTGGGACTGGGTGATTCTCATCCTCACCTTCTACACGGCCATAATGGTGCCCTACAATGTGTCCTTCAAGACCAAACAAAACAACGTCACCTGGCTGGTAGTAGACAGCATTGTGGATGTGATTTTCCTGGTGGACATTGTGCTCAACTTCCACACAACCTTTGTTGGACCCGCTGGGGAGGTGATCTCAGACCCAAAGCTCATCCGCATGAACTACGTGAAGACCTGGTTCGTCATTGACCTCCTCTCCTGTCTTCCTTATGATGTCATTAATGCCTTTGAGAACGTTGACGAGGGCATCAGCAGCCTCTTCAGTTCTCTGAAGGTGGTGCGTTTGTTGCGACTCGGGCGTGTGGCCCGCAAGCTGGACCACTACATTGAATATGGTGCGGCGGTGCTGGTGTTGCTGGTTTGTGTGTTCGGCCTGGCCGCCCACTGGCTAGCCTGCATCTGGTACAGCATCGGTGACTATGAGGTCATAGATGAGGAAGCCAACATGGTCCGTACGGACAGCTGGCTGTATCTTCTGGGAGAATCTGTTGGTACACCATATCGCTTCAACGCCAGTGGCACGGGGAAGTGGGAAGGGGGTCCCAGCAAAGATTCGGTCTACATCACGTCATTGTATTTCACCATGACCAGCCTGACCAGTATTGGCTTTGGGAACATCGCCCCCACCACAGATGGAGAGAAGATCTTTGCCGTGGCCATGATGATGATTGGCTCTCTCCTTTATGCCACCATCTTTGGTAATGTAACCACCATCTTCCAGCAAATGTATGCCAACACCAACCGCTACCATGAGATGTTAAACAGCGTGAGAGACTTCCTGAAGCTCTACCAGGTTCCCAAGGGCCTCAGTGAGAGGGTCATGGACTATATCGTCTCGACATGGTCTATGTCCAGAGGAATTGACACTGATAAGGTGTTGCAAATTTGCCCCAAAGACATGCGAGCAGACATCTGCGTTCATCTCAACAGGAAGGTGTTCAAAGAACATCCGGCTTTCCGTCTGGCCAGCGACGGCTGTTTAAGAGCCCTTGCCATGGAGTTTCAGACCATCCACTGCGCCCCGGGCGACCTCATCTACCACGCTGGTGAAAGCGTGGACAGCCTCTGCTTTGTCGTGTCAGGGTCTTTGGAGGTCATCCAGGACGATGAAGTCGTTGCTATTTTGGGAAAGGGAGATGTATTCGGGGATGTGTTCTGGAAAGAGGTGAATTTAGCTCAGGCTTGTGCAAACGTTCGTGCACTGACCTACTGCGATCTTCACATCATCAAGCGTGATGCCTTACAGAAGGTTCTGGAATTCTACACAGCCTTTGCCGGCCACTTCTCACGGAATCTGGTGCTAACCTACAACCTGAGGAAGAGGTGCTGCTCCCACCGTACATCTCATAGTCATCCGTCTGACCTGATAGAAAATCCATTTGTTTTTGCACTTTACAATGCATCTAAGTGGCTTCATCAGGAAGCACAGCCATGTGACCTGATCGTCTTCCGTAAAATAAGTGACGTCAAGCGGGAGGAAGAGGAAATGCTGCGAAGGAAGAATGAAGCCCCTCTGAATCTTCCTCCAGATCACCCTGTGCGGCGTCTCTTCCAGCGATTCCGCCAGCAGAGAGAGGCCCGTCTGGCGGCGGAGCGAGCAAGTCAAGGAGAACAGGATGTCGAGAAAGGCAGAGTGGAGACTATGATGCCAACTAGCATCATCACGGTCACTGAAAGTCCAGCCTCTCCAGTTACGTCTTCACCCACTTCATCATCATCAACATCATGTCGAGCAAAACGTTACACTCCCTTGGCTCCTAATGGAAACTATACAAGAAATAAGTCAGCAGAACCACTCAAAAACAAAGGCTGGGGTCGGTTTAAAGATGCCACAGCCAAGTCTGATCTCTCCTGGTGTCCTGTGTCCAAAGCCGAGTCCATGGAGATGCTACCAGACAGGACTAAGTCGCAAGATGAACTGTCCCTCAAGAAGACGGACTCGTGCGACAGTGGCATCACAAAGAGTGACCTGCGACTCGACAATATGGGTGACAGTAGCACTCGAACCCCTCAGGATCGGAGCCCCATGCAGCCTGAGGGGAAACGAATTTTCCACCCCATTCCTGAACACAGTCTTCAGGCCTGCTTTACAGAACTGAAACAGGAGCTACAAGGAGACATCCACTCCCTCAGCAGCAGAATGAGCGCACTTGAAGCGCAGCTTGCAGAGATGCTCCAACTTCTCAAAGACAGAAAGACCTCAGGATCTTCGAACTTGTTTGACATATCAAGGCCGGACTCTCCAGATTCAGAAAAGGACATGTTCTCCTAGCTGTGTTTTATGTCTGATGCAATGGGCTGAAGGGAAGATGGTTTGATCCTGTTCTAGTCCAAGCCAAACTGACCTCAACTAGTATTTTACTTTAAAGGTGAAGTATGCAGGATTTGTTATGTTAAAATACATTCTCTTCACCCAGTTTATTGTTGATTGACTACTGTTATTTTGTCATTCATGAGTTTCTGAAAAGTGTAAACATTGAGCCTCGCAGGCACCATCAAAGCATTAAGAGCATCTATGGCTGCTGTTGCAGGCTGAGAGTTTGGGGCATGGCTATTGTAGCAGGCTGAAAGTTTGGGGTGTGGCTACTGTAGCAGGTTGAGAGTTTGGGGCGTGGCTACTGTAGCAGGCTGAGAGTCGGGGGGCGTGGCTACTGTAGAAGGCTGAGAGTTTGGGGCGTGGCTACTATTGCTGGCTAAGAGTTCAGGGCATGGCTACTGTAGCAGGCAGAGATAGAGTAATGATCTACAGTAGACTCTTCAGTACCACAGCATCATCATGCACCCATTCAGAAAGATAAATGTACTGGTTTATATTGTTTATTTAGATGTGTCCAGTGTAGACAGCATCATGTCAAAAAATGCACCCATGTGCAGATATGTTGGATGGGTTTATTATAAGCAAGATGCTCACTTTCGCTCTAGACAGAGTGTGTTACTCCATTGCTTACTCATGAAATAGCAACACAACTAAAAGTACTCTTAATATGTTGGACCTTTTATTGAAAGTAGCCAACATGCCTTAACAAGCCCCTGTAAGAGCAGTCTGTGATGTTTGAGTTGGGGGAGGCACGGCACGTAAAAGGGGCATTTGCAAGGATGTTTGAAGAAATGCTTTATTTTTGTAATTCCGCTAGGTGCCACTAATGTTGCAGAAATGACATACTTCACCTTTAAAGATGAAGAGTGTAATTTTTTCTGTGTTAAAGTACTTTATTCTTTTGTCTGAGCCATAACCTAGTGGGCAGCACTCATATGGTGTAACGCTGCTTTGGCTCGTTATTTTTGCAGTTCTGTTTGTTGGAACAAGAATTACACATTTCAGCTATAATAAGCAACACATTAATGAATATATGGAACTTACATATAATGGAATATACCAGTATATTACTATAAAACCAGTTGTCAATTTTTGTACAGTCATCTAAATCAACATATATTTGTATTTGTGAGATGTACAACTGCCGTCTGTCTTTTTCTCACATCTGTCAAATCATATGTCAGATTTCAATGTCAGATCATTTGTCAGTCAATCAAGCAAAAGACAAAGCTGATTATAATGATTTAAACAATGGGCCCCATTCATGAACAAGAGCAGAATTAATTTCTGTGTAAAATTACTGAGTAGAATTATTGCATTCA

Function

symbol description
kcnh1b Enables voltage-gated potassium channel activity. Acts upstream of or within hindbrain formation and somitogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in gill; nervous system; pleuroperitoneal region; and trunk. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human KCNH1 (potassium voltage-gated channel subfamily H member 1).
kcnh1 Enables delayed rectifier potassium channel activity and phosphatidylinositol bisphosphate binding activity. Involved in several processes, including cellular response to calcium ion; phosphatidylinositol-mediated signaling; and potassium ion transmembrane transport. Located in early endosome membrane. Is integral component of plasma membrane. Part of voltage-gated potassium channel complex. Implicated in colorectal adenocarcinoma. Biomarker of hepatocellular carcinoma and renal cell carcinoma.

GO:

id name namespace
GO:0042391 regulation of membrane potential biological_process

KEGG:

id description
K04904 KCNH1, KV10.1; potassium voltage-gated channel Eag-related subfamily H member 1

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000015_00690873_00738349.mRNA True 4774 mRNA 0.47 12 690478 739716

Neighbor

gene id symbol gene type direction distance location
CI01000015_00677822_00681741 NA coding upstream 8672 677755 ~ 681806 (+)
CI01000015_00670047_00675766 NA coding upstream 14496 669599 ~ 675982 (+)
CI01000015_00625163_00648377 NA coding upstream 41499 625163 ~ 648979 (+)
CI01000015_00481072_00489281 NCBP2 coding upstream 201197 481072 ~ 489281 (+)
CI01000015_00469983_00471517 RBBP9 coding upstream 218698 468804 ~ 471780 (+)
CI01000015_00749679_00758875 NA coding downstream 9665 749381 ~ 759297 (+)
CI01000015_00790715_00793401 COMMD2 coding downstream 50724 790440 ~ 794661 (+)
CI01000015_00800582_00853181 WWTR1 coding downstream 60866 800582 ~ 853181 (+)
CI01000015_00886425_00888351 TM4SF18 coding downstream 145515 885231 ~ 888806 (+)
CI01000015_00890625_00902801 CP coding downstream 150909 890625 ~ 902996 (+)
G86933 NA non-coding upstream 33752 656227 ~ 656726 (+)
G86932 NA non-coding upstream 34331 655932 ~ 656147 (+)
G86931 NA non-coding upstream 34556 655318 ~ 655922 (+)
G86908 NA non-coding upstream 98881 590779 ~ 591597 (+)
G86783 NA non-coding upstream 197644 491955 ~ 492834 (+)
G87246 NA non-coding downstream 261525 1001241 ~ 1001459 (+)
CI01000015_01002365_01011214 HYKK non-coding downstream 268787 1002365 ~ 1011275 (+)
G87249 NA non-coding downstream 269656 1009372 ~ 1009607 (+)
G87253 NA non-coding downstream 273868 1013584 ~ 1013801 (+)
CI01000015_01015968_01016675 NA non-coding downstream 276159 1015623 ~ 1017700 (+)
G87432 NA other downstream 871367 1611083 ~ 1611387 (+)
G87972 NA other downstream 1136288 1876004 ~ 1876594 (+)
G88172 NA other downstream 1644300 2384016 ~ 2526510 (+)
CI01000015_02512276_02523824 NA other downstream 1772382 2511546 ~ 2524572 (+)
CI01000015_03011472_03026518 NA other downstream 2283280 3011472 ~ 3026636 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_020611 kcnh1b coding NC_007133.7 CM002906.2 37902976 ~ 37952513 (+)
bowfin (Amia calva) AMCG00001443 LOC108411957,LOC107753489,LOC108270513,LOC105026838,LOC106564801,LOC103369331 coding CM030143.1 CM030143.1 4471081 ~ 4484279 (-)