XLOC_010550 (has2)


Basic Information

Item Value
gene id XLOC_010550
gene name has2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 15369634 ~ 15387459 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00020686
AAAAAGAGTCCTGCGAATGTAAGGCTTACAGGAAACATAAACTTAAAGCGTCTGGAAGAAATTAGGCGCAGAAAAAGACAAGTCCACTACTTCAACCTGTGcgcttggggaaaaaaaaaacttgaatgaaTTACAGCTTGATTCACCAACATTGACTACTGTTGGATgacttttttaaagataaagaagaaaaaaacgtttaaagtcattttttttcttttcttaaattaGCTGACAACTTCAGAATGAACTTCCAAAATGTTCACGCAGACCTCATCACGACAGCAAACTGATGCaaactttaaataatgttttggacGAGGCGAGATGTTATGTGGAAAACGTGGATACTGTACATTTTTGCAATTCAAAACAAGGAGTTTTTAGATGCTCCATGCCGGTCTCCTCTATACTTTCCCCCAAAACTTGTATGGGAAGGTTTGTAGAGTGTCTGGAGAGTGCAGACCCTCGTCGGACAGCATCCCTGTTCAACTAACGGGACATCTCCAAAGAGCTGCTCCAAGATGAGATGTGATAAAGCGGTCAGCTACTTAAGGATTGTTGGGACGACACTGTTCGGCATTTCACTGCTTGTGGGAATCTCTACTGCTTATATCATGGGGTATAAGCTTGTAACAACTCCGGGCAACTATTTGTCCTTTGGTCTTTATGGAGCAATTCTTGTCATCCACCTCATCATCCAAAGTGTGTTTGCCCTACTGGAACACAGGAACATGAAACGCTCCCTGGAAACACCAATCAAACTCAACAAGTCACTGGCCCTATGCATCGCAGCCTATCAGGAAGACCCCAACTACCTGAGAAAGTGTTTAATATCAGTGAAGAGGCTCACGTATCCGGGTATAAAGGTCATAATGGTTATCGATGGGAACAACGATGATGACTGCTACATGATGGAGATCTTTCGAGAAATCATGGGCCGGGACAAGGCAGCCACGTACATTTGGAAAAGCAACTATCACCACAGAGGACCCGAAGAAACTGAAGAATCATACGCAACAAGCTTGCAGCATGTTTCTCACCTGGTTCTCAATAATAAGTGTGTGTGCATCATGCAGAAGTGGGGCGGGAAAAGAGAGGTCATGTACACCGCCTTCAAAGCCCTGGGAAGAAGTGTTGACTATGTACAGGTTTGTGATTCAGACACCATGCTGGACCCGGCCTCCTCTGTAGAGATGGTGAAGGTTCTAGAAGAAGATCCCAATGTTGGAGGAGTAGGTGGAGATGTGCAGATATTGAACAAATATGAGTCGTGGGTCTCCTTCCTGAGCAGCGTGAGGTATTGGATGGCGTTCAACATTGAAAGAGCCTGCCAGTCATATTTCGGGTGCGTTCAATGTATCAGCGGACCCTTGGGAATGTACAGGAACTCCCTCCTCCATGAGTTCCTGGAGGACTGGTATGATCAGACTTTCATGGGAAGCCACTGCAGTTTTGGCGATGACCGCCATCTGACCAATCGAGTACTGAGCTTGGGATATGCCACGAAATACACCGCGCGCTCCAAGTGCTTGACCGAGACGCCCATTACCTACCTGCGCTGGCTCAACCAACAAACCCGCTGGAGTAAATCCTATTTCAGAGAGTGGCTTTACAACTCCTTGTGGTTCCACAAGCACCACTTGTGGATGACTTACGAGGCCGTCATCACCGGCTTCTTCCCGTTCTTCCTTATCGCCACTGCCATTCAACTGTTCTACCAGGGCAGGATCTGGAATATCCTTCTGTTCCTGCTGATCGTCCAGGTCGTGGCACTCATAAAGTCCTCATTTGCCAGTTGCCTCCGAGGCAACATAGTCATGGTCTTCATGTCATTCTACTCAGTGTTATACATGTCAAGTCTGCTACCGGCAAAAATGTTTGCAATAGCCACCATAAACAAATCCGGATGGGGAACGTCTGGAAGGAAGACCGTGGTGGTGAACTTCATCGGACTCATTCCAATCTCAATTTGGTTCACTATTCTTTTCGTTGGCATTATTTATACCATAATCCAAGAGACGCGAAAACCCTTTCCTGAATCCGAAAAGGTGGTTTTGATAATTGGCGCAATCGTTTATATCAGCTACTGGGTTGTGTTTTTGACTTTGTACGCTGTCCTCATTATGAAGTGTGGCAAGAGGAAGAAAGGACAGCAGTATGACATGGTTCTTGACGTATAGTATTTCCCGTGCCCTTCATCCTTTTCTACGTTTACATTAAAGACAGACTGCTATCTGAATGTGGACCTTCCACAGGAAGTGACACTGTAAGGAGACATCAATGCTGCTGTGACTGTCACTAAGAGTATTCCTTTAAAGTGATGAAGGAATATGTTTTGATATGTGAGCTTTGACAGTCTTGATGTTTTAGTTATCCACCATCAGATGACAATTTCTTTGCACTTTTACAATCACTCTTGTTATACATAATGCTTGATATAGAACTTTTAAGGAACAAAATACCTCAGTGGTTGTGTTAGCATTGTGTGAGTGTTTGGGATAGTCTGTGAGActgttttttatgtaatttatgattttttatcaaaaaatttttttgttttatatatatatatataaaatatataatgtatacatttttgaCTGAAATCCAAAACAGAATTTGTGCTGTACTTTTGtttgcataatgtattttattgccTTTttatagatcttttttttttccttttttttattatcaccAAAGATTCTCTATTTTCATTAAATATGaggaaatgtaatgttttaagaCTTGCCTATCTGACCAAAATGTGAAATTAGGAGCTGGATTTGTCTCTGTGATGACAGCAATAAAAGGCAAATCTATGGATAAGTTATTCATTTTCTTTGACAATAAGGGCGAAAAACCTGTGTTATAAGTATATGGAGGAAAGACCAGTCTATTTATATGGTTTATAGCTTTATTACATGATTGTTAGctaaatatttgtaatatgaaAATGTCATTTGCTGGTTCGATTGAATGTTTTGAATTGTCCCACACAAACTATGCAATTTCAGCATGTGCCAATGTCAAATTGCAATGCAAATTCCCAAGAAAAAGTGACACAGGAACatttgcacatgcacacacacacacattggtattTGTGGTTTACAGGTACTCTTTGTAGGCATAAAAGTagtcactgtaaaataaaataaaaaacaaaacgtgTTATATGACCCTACCCACACCTACACCGTTAATTCTAACAGGAAACtagtgaaaaatattaaatttaaaaaagtatgattattaagcattttgaattacaaggacacataAACCTTTCATTATATAATAAATCCTGTAAACTACACACAAAACAAAGGCACTGATACCTTGTTTCATACAACATTCTGAAATCTATCAACATTTGCATTGCTTTTCCAGTGATACCAAACCTGAATTTTCAAGTAGCACTGTGCCTTATTATCTTGGGAAAGCcttgattttatttattgaacatgaaAAGACCCCCAAAAAGTGTGTttattaagcattttgaattatttattcattttctcgtcggcttagtccctttattaatccggggtcgccacagctgaataacccgccaacttatccagcaagttttttacgcagcggatgcccttccagccgcaacccatcttttggaaacattcacatacacattcacacacacactcatacactatggacaatttagcctacccagttcacctgtcccgcatgtctttggactgtgggggaaaccggagcacccggaggaaacccacacgaatgcagggagaacatgcaaactccacacagaaatgccaactgagctgaggttcgaaccagcgaccttcttgctgtgaggcgacagcactacctactgcgtcactgcctcgCCCATTTTGAATTTATAAGgacacaaaacattttctcataAACTACCGTAATAGAGTACAACCCCCTGTCCTTATATGATAAAACCTATAAACCACACACAGACAAAGGCGCCAATACCTTGTGACCGCTGTTGTTTTATACAACCTTTTGTAATCCATCAACATTTGCATTGCTTTTCCAGTGATACCAAACTTGAATTTCCAAGTATCACCATGCCTTAATATCCTGGAAAAGCcttgattttatttattgaatgtgAAAAGACCCTAAAGCGTATGATTAGTACatattttgaattacaaggacacaagaCATTTTCTCATAAACCACTGTAGTGAGTACAACCAcctgtttaattatttaacaaaacctgcaaaccacacacacacaaaggcatcAATAGCTTGTGACCGTTGTTTTATACAACCTTGTGTAATTCATCAGCATTTGCATTGCTTTTCCAGTGATACCATACCTGTATTTCCAAGTATCACCATGCCTTAATATCCTGGAAAAGCCTTGATTTTATTTACcagcaatttttttaatgtttaccaaatgttttaatgttatgGTTTGAATTATATACAAAAGAGGCAACTTTTGATGATAAGTATAGTGTTTTTGTAGTACAGTAAAAATTTGATTGTAATTGATGAGGGCTTTTTTGAGGCAGTATTGTCATAAAGCACTTTTGTGTTTGtgccaaataataaaaaagtacattataaTGCC

Function

symbol description
has2 Predicted to enable hyaluronan synthase activity. Acts upstream of or within several processes, including ameboidal-type cell migration; circulatory system development; and fin regeneration. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; mesoderm; pericardial region; presumptive paraxial mesoderm; and swim bladder bud. Orthologous to human HAS2 (hyaluronan synthase 2).

GO:

id name namespace
GO:0042074 cell migration involved in gastrulation biological_process
GO:0021535 cell migration in hindbrain biological_process
GO:0036302 atrioventricular canal development biological_process
GO:0001756 somitogenesis biological_process
GO:0035810 positive regulation of urine volume biological_process
GO:0003146 heart jogging biological_process
GO:0070295 renal water absorption biological_process
GO:2000223 regulation of BMP signaling pathway involved in heart jogging biological_process
GO:0003171 atrioventricular valve development biological_process
GO:0035050 embryonic heart tube development biological_process
GO:0003181 atrioventricular valve morphogenesis biological_process
GO:0030213 hyaluronan biosynthetic process biological_process
GO:0045226 extracellular polysaccharide biosynthetic process biological_process
GO:0001568 blood vessel development biological_process
GO:0031101 fin regeneration biological_process
GO:0085029 extracellular matrix assembly biological_process
GO:0060030 dorsal convergence biological_process
GO:0001947 heart looping biological_process
GO:0008078 mesodermal cell migration biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0050501 hyaluronan synthase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-020828-1 Predicted to enable hyaluronan synthase activity. Acts upstream of or within several processes, including ameboidal-type cell migration; circulatory system development; and fin regeneration. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; mesoderm; pericardial region; presumptive paraxial mesoderm; and swim bladder bud. Orthologous to human HAS2 (hyaluronan synthase 2).

Ensembl:

ensembl_id ENSDARG00000036987

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00020686 True 4614 mRNA 0.40 4 15369634 15387459

Neighbor

gene id symbol gene type direction distance location
XLOC_010549 sntb1 coding downstream 106535 15164983 ~ 15263099 (-)
XLOC_010548 mrpl13 coding downstream 272121 15052513 ~ 15097513 (-)
XLOC_010547 dscc1 coding downstream 782302 14572008 ~ 14587332 (-)
XLOC_010546 si:dkey-237j11.3 coding downstream 817435 14528374 ~ 14552199 (-)
XLOC_010545 BX324006.2 coding downstream 926245 14421800 ~ 14443389 (-)
XLOC_010551 CT573793.2 coding upstream 320745 15708204 ~ 15709144 (-)
XLOC_010552 CT573793.3 coding upstream 391700 15779159 ~ 15780407 (-)
XLOC_010553 NA coding upstream 398778 15786237 ~ 15786804 (-)
XLOC_010554 CT573799.2 coding upstream 426047 15813506 ~ 15814501 (-)
XLOC_010555 UBE2O coding upstream 555428 15942887 ~ 15988320 (-)
XLOC_010626 CR392024.2 misc upstream 5507653 20895112 ~ 20895175 (-)
XLOC_010544 NA non-coding downstream 952227 14416346 ~ 14417407 (-)
XLOC_010540 BX322530.1 non-coding downstream 1201961 14093781 ~ 14167673 (-)
XLOC_010539 NA non-coding downstream 1278932 14088331 ~ 14090702 (-)
XLOC_010536 NA non-coding downstream 1364025 13976380 ~ 14005609 (-)
XLOC_010562 NA non-coding upstream 879097 16266556 ~ 16270435 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000016_06508677_06514489 HAS2 coding CI01000016 null 6508137 ~ 6514489 (-)
bowfin (Amia calva) AMCG00002611 has2,LOC107673001,LOC107596747 coding CM030136.1 CM030136.1 22694206 ~ 22705745 (-)