XLOC_017076 (lama2)


Basic Information

Item Value
gene id XLOC_017076
gene name lama2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 1903481 ~ 1979652 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034090
CAGATGTGTGCGCTGGGCTACCGGCGGGTCAACGGGACGATCTACCGGGGTGTGTGTGAACTCTGTCAATGCCACGGACACACAGAGCGCTGTGATGACCTCACTGGACACTGCCTGgGCTGCAGGGATCACACTGTAGGACCGAACTGTGGCCAGTGTGCTCCTGGATATTATGGAGACGCCACTAGAGGAACTGCAGACGACTGTCAGCCCTGCGCCTGTCCTCTGCTGAGCCCCGCAAACAATTTCAGTCCCACGTGTCGTGTGGATGGCAGGGGCGAGGTGATCTGCGACCGATGCCCGCCGGGGTACACCGGATCACGCTGCGACAGGTGTTCTAATGGCTATTTCGGACGTCCCAATATTCCTGGCGGCTCCTgtcagccgtgtgtgtgtagcGGTAACCTGGACCAAACCGCTCCGCTGAGCTGTGACCCGCTGACCGGAGCCTGTCTGCGCTGTCGAGAGGGATACGGAGGAGCTGACTGCGAACGCTGCGCTGACGGATACTTCGGAGATGCCCTCATAGCCAAGAACTGCCAAGCGTGTCAGTGCCACAGTAATGGAtcagtgtcagagctctgccatcAGGAGACAGGACAGTGCCAGTGTCGCCAGCACGTGATTGGACGGCAGTGTGACGAGTGTATGgctggCTCTCATCTGCAGGGCGCTCTCGGCTGTGTCCCGTGCCACTGCAACTCTTTTGGCTCCAAATCGTTTGACTGTGATGAGAGCGGGCAGTGCCGCTGCCAGCCCGGTGTCACGGGACAGAAGTGTGACCGCTGCGCCGCTGGACACTTCAGCTTCCAGGAGGGAGGATGCACACCGTGCCAGTGTGCCCATGTGGGAAATAACTGCGACGCCAGCACGGGCCAGTGTATCTGTCCGCCCAACACCGTGGGAGAGCGATGTGACAAATGTGCGCCCAACCACTGGGGTCACGACATCAGCACGGGCTGCAAGCCGTGTGGCTGTAATGCACTGGGGTCTGTGGCGCAGCAGTGTAACCTGAACACCGGCTGCTGCATGTGCCGAGAGCAGTTCAGGGGGGAGAAATGCGACGAGTGTAAGCTTGGATACAGAGATTTCCCACAATGCATTTCCTGCCAGTGCTCTGCAGCAGGCTCATCGCTGGACACCTGCGACTCAGAGTCAGGCCTCTGCGCATGTGCGGACAGAAGCGGACAGTGCTCCTGCAAGgctAATGTGGAGGGCCAGAAGTGTGAGCGCTGTAAGAGCGGCTCATTCGGCCTCAGTCACAGGAATCCTCTGGGCTGCAGTCGCTGCTACTGCTTTGGCTTGAGCAGCTCCTGTACAGAGGCCACAGGACTCATCCGGATGAGGCTGACTCTGATGCCCGAGCAGACTGTTCTTCCTCTGGTGGACCGTTCTGGACATCAGGAGACCACAGCAGGCATCACTTTCCAGCATCCAGACATCATCGCCACCGCAGACGTGGTCCAGCAGCAGCTGAGTGAGCCGTACTACTGGAGACTGCCCAAACAGTTCAAGCGCTCCATGATAACGGCCTATGGTGGTAAGCTAAGGTACGCCATATATTACGAGGCCCGTGAGGAGACAGGACGCACCTCATATGAGCCTCAGGTCATCATTAAGGGTGGCCCGAATAAAGACAAGATCATGGTGCGGCACATGCCTGCGCTTCAGATTGGCCAGCTGACCCGCCATGAAATCGACATTACAGAGCACGAGTGGAAACACAAGGACGACAGGCCCATGTCTCGAGAGGACTTCATGGACGTTCTGTTTCATGTGGAATATATACTAATAAAGGCTTCGCACGGCAACGTCATGAGGCACAGCAGgatTTCTGAGATCACTCTGGAGGTGGCGGAGGTGGGCAGAGCATCCCAGGACAGTGAAATCGCCCATCAGATTGAGAAATGTGTGTGCCCTCAGGGATACGCCGGTCTCTCCTGTGAGGAGTGTGCGGCCGGGTTCTACAGACTCTCGGTTCTGGCTGGTGGATCTGCATCGCGGGCCGGTTTTGGCAGCTGCGTTCGCTGCCAGTGCAATGGGCACAGCGACTCCTGTGACCCCGAAACCTCCATCTGCCAGAATTGTCAGCACAACACAGTGGGTGATAAGTGTGAGCGCTGTGCTGCGGGGTTTTACGGTGTAGTGCGAGGATTTACAGACGACTGCAAACCCTGCGCCTGTCCACTGCTCAACCCTGAGAACAACTTCAGTCCCACCTGTCAGACGGAGGGTTTTAATGAGTACCGCTGCACCGCCTGTCCTGAAGGCTACGAGGGAAAACACTGTGAAAGGTGCGCTCCTGGTTTTCACGGTGACCCCGGGGTGCTGGGCGGCCGCTGTGAGGAGTGTAAGTGTGACCCGTACGGTGCTTTCCCCTCAGCGTGTGACTCTCACTCTGGGCAGTGCCAGTGCCGTCCCGGTGCCAGCGGACTGAAGTGTGACCAATGCATGGAGAGGCATGTGTGTGGCCCTGAGGGCATCGTGTGTACGTATAACAGCAGCAGTGctaacacactcacacatttgAAGAGG

Function

symbol description
lama2 Predicted to be an extracellular matrix structural constituent. Acts upstream of or within muscle attachment and myelination in peripheral nervous system. Predicted to be located in extracellular region and membrane. Predicted to be active in basement membrane. Is expressed in adaxial cell; head; musculature system; nervous system; and otic vesicle. Used to study congenital merosin-deficient muscular dystrophy 1A and muscular dystrophy. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy; congenital merosin-deficient muscular dystrophy 1A; muscular dystrophy; and myopia. Orthologous to human LAMA2 (laminin subunit alpha 2).

GO:

id name namespace
GO:0045995 regulation of embryonic development biological_process
GO:0007517 muscle organ development biological_process
GO:0030155 regulation of cell adhesion biological_process
GO:0009887 animal organ morphogenesis biological_process
GO:0009888 tissue development biological_process
GO:0016203 muscle attachment biological_process
GO:0060538 skeletal muscle organ development biological_process
GO:0007411 axon guidance biological_process
GO:0030334 regulation of cell migration biological_process
GO:0022011 myelination in peripheral nervous system biological_process
GO:0007155 cell adhesion biological_process
GO:0005604 basement membrane cellular_component
GO:0005102 signaling receptor binding molecular_function
GO:0005201 extracellular matrix structural constituent molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060119-1 Predicted to be an extracellular matrix structural constituent. Acts upstream of or within muscle attachment and myelination in peripheral nervous system. Predicted to be located in extracellular region and membrane. Predicted to be active in basement membrane. Is expressed in adaxial cell; head; musculature system; nervous system; and otic vesicle. Used to study congenital merosin-deficient muscular dystrophy 1A and muscular dystrophy. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy; congenital merosin-deficient muscular dystrophy 1A; muscular dystrophy; and myopia. Orthologous to human LAMA2 (laminin subunit alpha 2).

Ensembl:

ensembl_id ENSDARG00000099390

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034090 True 2535 mRNA 0.58 17 1903481 1979652

Neighbor

gene id symbol gene type direction distance location
XLOC_017075 CABZ01065423.1 coding upstream 11885 1834262 ~ 1891596 (+)
XLOC_017074 NA coding upstream 178433 1663759 ~ 1725048 (+)
XLOC_017073 C20H6orf58 coding upstream 482476 1412193 ~ 1421005 (+)
XLOC_017072 C20H6orf58 coding upstream 497173 1398564 ~ 1406308 (+)
XLOC_017071 mmachc coding upstream 510461 1385674 ~ 1393020 (+)
XLOC_017078 CABZ01092781.1 coding downstream 16550 1996202 ~ 2035120 (+)
XLOC_017079 CABZ01088134.1 coding downstream 59866 2039518 ~ 2054547 (+)
XLOC_017080 BX681416.2 coding downstream 119591 2099243 ~ 2146546 (+)
XLOC_017081 l3mbtl3 coding downstream 155164 2134816 ~ 2206310 (+)
XLOC_017082 NA coding downstream 234037 2213689 ~ 2214421 (+)
XLOC_017070 NA non-coding upstream 547798 1354663 ~ 1355683 (+)
XLOC_017065 NA non-coding upstream 699607 1200292 ~ 1203874 (+)
XLOC_017061 NA non-coding upstream 1003101 896905 ~ 900380 (+)
XLOC_017056 NA non-coding upstream 1221189 681847 ~ 682292 (+)
XLOC_017084 BX681416.1 non-coding downstream 282281 2261933 ~ 2266612 (+)
XLOC_017085 NA non-coding downstream 301972 2281624 ~ 2284813 (+)
XLOC_017087 NA non-coding downstream 501258 2480910 ~ 2481815 (+)
XLOC_017088 NA non-coding downstream 527248 2506900 ~ 2508095 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000135_01069416_01096641 NA coding CI01000135 null 1069163 ~ 1096689 (-)