XLOC_021103 (map2k2a)


Basic Information

Item Value
gene id XLOC_021103
gene name map2k2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007133.7
NCBI id CM002906.2
chromosome length 39133080
location 20388621 ~ 20403194 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00041460
TGGCCGGACTTTTTCCCCCTCCTTTTTTCTTGGGGGAAATTTCAACTTCTGTTTTCGCGGCTCCTCCGAGCCAAACTATTTCGGACAGCGTTTCTCGCCCGGTCCTGAGGCTGTGAACGATAGGCCTAACTTGTCTTTTGCCGCCTTTTGTCTGTGGGAGCGCTCGCGAGTCAGAGGCCGTGCCGGAGAGACATTCCAGCGATGCACGcgcttaaataaactgcatttccTGCACTTTTACCTCTGAGCCACTCGCTTTTTCATTTGACACTTTAATTTCACCTGGAGCAGCTTTTGAGAGCATGATTGGGTGTTGAAATTTGGGGCTTGCTAATCTCAGAAACTTCCACTACAAGGGTTTGTGTATCAGTTTGAAGTATTGGATGTCAGTAGAGACAACCTGGTTGCTTTCTTTGAAATTGATAACTTTGCAAGTATGGCACCAAAAAGAAGACCAGTCCCCTTGATTATAACCCCCACTGGAGAGGGACAGTCAACCAACATTGATGCAGCAGCAGAGGCCAACCTGGAGGCCTTGCAGAGGAAGTTAGGTGAGCTGGATTTGGATGAACAGCAGAGGAAGCGCCTCGAAGCTTTCCTCACCCAGAAAGCCCAGGTGGGCGAGCTCAAGGATGAAGATTTCGAACCCATATGTGAACTTGGCGCTGGTAATGGTGGAGTGGTTCATAAAGTCCGTCACAAACCCTCGAGACTGGTTATGGCCAGGAAGCTTATACACTTGGAAATCAAACCAGCCATCAGGAACCAGATTATTCGAGAGCTGCAGGTTCTACACGAGTGTAACTCACCGTACATTGTAGGGTTTTACGGCGCCTTCTACAGTGATGGAGAAATCAGCATCTGTATGGAGCACATGGATGGAGGCTCTTTGGATCAAGTGCTCAAAGAAGCCAGAAGAATCCCTGAGGAAATTTTGGGCAAAGTTAGCATAGCTGTACTCAGAGGTTTGGCGTATCTTCGGGAGAAGCACCAAATAATGCACAGAGACGTTAAGCCCTCCAACATCCTGGTGAACTCGCGCGGTGAGATCAAACTGTGCGACTTTGGTGTGAGTGGCCAGCTCATCGACTCTATGGCCAACTCCTTCGTTGGAACACGGTCGTACATGTCGCCGGAGAGACTCCAGGGCACGCACTACTCGGTTCAGTCGGATGTGTGGAGCATGGGCCTATCACTGGTTGAGCTTGCTATTGGACGCTACCCCATCCCCCCTCCCGATGCTAAGGAACTGGAGGCCATATTTGGCCGGCCAGTGCTGGATGCAGGTGGGGCAGAAGGTCACAGCATGTCTCCAAGACCCAGGCCTCCAGGACGACCAGTTAGTGGACACGGAATGGACAGCAGGCCAGCAATGGCTATATTTGAGCTACTGGACTACATTGTCAATGAGCCTCCACCCAAGCTCCCCCATGGCGTCTTCACCACAGACTTTGAGGAGTTTGTGACAAAATGccTCATAAAGAACCCTGCTGACAGAGCTGACCTCAAGATGCTAATGGGTCACACGTTCATCAAGCGGGCTGAGGTTGAGGAGGTGGATTTTGCTGGATGGTTGTGTAAAACCATGGGCCTTCACCAGCCTAGCACACCCACTCATAGCGCTGAATGAATGCTGGCTCATACCGTTGCCACCCATGCCATCCTCCACTCTACTTCTGTCCTCTTTGCTCTCACAGGCCTGTATGCTTGTAAGCCTCCGACACACCGCTGTGCACTCTTTTGCCGTTCTCTGCTTGCTCTTCCCTTCCGCTGCAGTGCGTTCTGGGGGCATTGTTTTATAGGAGCCTCTGGTGTTGGAACACTTGGTCATTTGAACGAATATGGAGATTTATAGTCACTTAAGTGAAGTGGCTGTATTTTTAACGACCAGCTTATTCAGGAATGTGTCCAAAATGGTTAAGATCAACTGGGTTTTGGTTTTGTATAACAGCATTTTCATTAGCTTTATGATGCTTTTCTTTTCACCGtctgtttattaattaatcacAATCACAATCTCTGTTGCTAATGTGCCATTCGTTGGCAATTAGCATTACACTGTGTTAAGATGTATAGCCTGGTTCAATGGCAAGCATTTCATTATGAATCAACTGCCGTTTAAAACAAGATAAAAGAATGAGAGAAAACCAAAGAGGGCTACTATGGATTATACACTATGGTTGGTTTATTACTAATTATAAGGCGATTATTATAAATGCAGGATGGCCAAATCACCAATTTATCAAGCACATGTGTACAAGTTTTTAACTTGTGCTTTGCATGGCCAGTCACACCAACAAATGGCCATGCCGTGAGTTTGCACACATTACCACATATTAAAAAAAGCTATATTAAAGTTCCTGTATCAGATGCCCTTAGTTCTGCTGTGCCTGTTAAAAAGATCTCTTTTAGTATTCATATTTGGTTTGAACACCATTTGATCCCCTTAACATTGGCCCTTAAAAATGTTTCATCGCATCTTTCTCAAGTATAGTTTAAATCATGCTTGACTCATTTTTGCGACCAGTGCTTGAACGGTTTTCTTAGAACGTGCTTTATTGAAATAATCTGTAGAAAAGTatatttgggtaaaattattgtttgtaatttaTGCTGTAATGTCTTTGATTTAAGTTTGAGTACAACCAGAGTTGCACAGTGCTTTTTCCATGGACTCTATGAATTTGAACACATCCAAATGACTCCAACTAAGACCACAACAGGTACACTCATGGTTTGAACTTTAGTGGTATATAAAGTGCAAAGTAATGTCTCAGGCCACCATGTACAGTGCTATGCAGATCCAATGAACCTCAGCAGATATTACCGTATTAGTGGGTCTTATAAATACACGGGTGTTACAGATGGGCATTGTGAAGTGTGGCTAAAGCCCACTTGTTCTGAATagctttgtgtttcttttttttcttctctgtaGTACTTTTCAGTAACATTGAAACCGTATTACACACTGGCATTCAGCTCTGACCAAGTGAATGCATTGCCACACTTgcgtgtataaaataaaatatgtacagtacAAACGGTACTGTTTTTCagtcttaaaaatagcattttatttttgttttgtttttttgactacTTTCGAGAAGAGGATCTAAGTCATTTTATTACCATATGGAATGTGTTGAATACAgttctaatataaaaataaaacttatttgtgAATGAT

Function

symbol description
map2k2a Predicted to enable MAP kinase kinase activity. Predicted to act upstream of or within protein phosphorylation. Is expressed in cardiac ventricle. Human ortholog(s) of this gene implicated in cardiofaciocutaneous syndrome 4 and small intestine adenocarcinoma. Orthologous to human MAP2K2 (mitogen-activated protein kinase kinase 2).

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0000187 activation of MAPK activity biological_process
GO:0016310 phosphorylation biological_process
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004708 MAP kinase kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-041027-1 Predicted to enable MAP kinase kinase activity. Predicted to act upstream of or within protein phosphorylation. Is expressed in cardiac ventricle. Human ortholog(s) of this gene implicated in cardiofaciocutaneous syndrome 4 and small intestine adenocarcinoma. Orthologous to human MAP2K2 (mitogen-activated protein kinase kinase 2).

Ensembl:

ensembl_id ENSDARG00000006609

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00041460 True 3193 mRNA 0.44 11 20388621 20403194

Neighbor

gene id symbol gene type direction distance location
XLOC_021102 zbtb7a coding downstream 1639 20372533 ~ 20386982 (-)
XLOC_021101 tcf3b coding downstream 46361 20312180 ~ 20342260 (-)
XLOC_021100 mbd3b coding downstream 79338 20267522 ~ 20309283 (-)
XLOC_021099 mbd3b coding downstream 126722 20246587 ~ 20261899 (-)
XLOC_021098 btbd2a coding downstream 221957 20159067 ~ 20166664 (-)
XLOC_021104 pias4a coding upstream 3216 20406410 ~ 20419660 (-)
XLOC_021105 atp8b3 coding upstream 70035 20473229 ~ 20515347 (-)
XLOC_021106 BX088720.1 coding upstream 87247 20490441 ~ 20490557 (-)
XLOC_021107 NA coding upstream 119010 20522204 ~ 20547540 (-)
XLOC_021108 lingo3a coding upstream 170668 20573862 ~ 20575679 (-)
XLOC_021094 NA non-coding downstream 750592 19622740 ~ 19638029 (-)
XLOC_021093 NA non-coding downstream 786159 19598045 ~ 19602462 (-)
XLOC_021090 BX936298.1 non-coding downstream 958697 19429806 ~ 19429924 (-)
XLOC_021089 BX936298.2 non-coding downstream 988686 19397226 ~ 19399935 (-)
XLOC_021088 BX927243.3 non-coding downstream 1172433 19215022 ~ 19216188 (-)
XLOC_021117 CU693455.1 non-coding upstream 715708 21118902 ~ 21119016 (-)
XLOC_021118 NA non-coding upstream 716702 21119896 ~ 21121096 (-)
XLOC_021124 NA non-coding upstream 1141016 21544210 ~ 21547893 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000030_03719059_03726730 MAP2K2B, MAP2K2, MAP2K2A, MP2K2, TMEK coding CI01000030 null 3718535 ~ 3727455 (-)