| Item | Value |
|---|---|
| gene id | XLOC_002268 |
| gene name | exosc8 |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007121.7 |
| NCBI id | CM002894.2 |
| chromosome length | 45420867 |
| location | 35002786 ~ 35011502 (+) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| exosc8 | Acts upstream of or within axonogenesis; cerebellar Purkinje cell layer structural organization; and myelination. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is expressed in alar plate midbrain region; immature eye; midbrain; and retina. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human EXOSC8 (exosome component 8). |
| id | name | namespace |
|---|---|---|
| GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' | biological_process |
| GO:0016075 | rRNA catabolic process | biological_process |
| GO:0071028 | nuclear mRNA surveillance | biological_process |
| GO:0071035 | nuclear polyadenylation-dependent rRNA catabolic process | biological_process |
| GO:0071038 | nuclear polyadenylation-dependent tRNA catabolic process | biological_process |
| GO:0071042 | nuclear polyadenylation-dependent mRNA catabolic process | biological_process |
| GO:0034473 | U1 snRNA 3'-end processing | biological_process |
| GO:0034475 | U4 snRNA 3'-end processing | biological_process |
| GO:0034476 | U5 snRNA 3'-end processing | biological_process |
| GO:0006396 | RNA processing | biological_process |
| GO:0006401 | RNA catabolic process | biological_process |
| GO:0043928 | exonucleolytic catabolism of deadenylated mRNA | biological_process |
| GO:0042552 | myelination | biological_process |
| GO:0000467 | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological_process |
| GO:0021693 | cerebellar Purkinje cell layer structural organization | biological_process |
| GO:0007409 | axonogenesis | biological_process |
| GO:0007420 | brain development | biological_process |
| GO:0000176 | nuclear exosome (RNase complex) | cellular_component |
| GO:0000177 | cytoplasmic exosome (RNase complex) | cellular_component |
| GO:0000178 | exosome (RNase complex) | cellular_component |
| GO:0017091 | AU-rich element binding | molecular_function |
| id | description |
|---|---|
| ZDB-GENE-030131-1736 | Acts upstream of or within axonogenesis; cerebellar Purkinje cell layer structural organization; and myelination. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is expressed in alar plate midbrain region; immature eye; midbrain; and retina. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human EXOSC8 (exosome component 8). |
| ensembl_id | ENSDARG00000068755 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00004337 | False | 969 | mRNA | 0.44 | 11 | 35002786 | 35011502 |
| TCONS_00004338 | False | 847 | processed_transcript | 0.42 | 9 | 35002798 | 35009437 |
| TCONS_00004339 | True | 407 | processed_transcript | 0.45 | 5 | 35005895 | 35009096 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_002267 | rfxap | coding | upstream | 41028 | 34958583 ~ 34961758 (+) |
| XLOC_002266 | CT573139.1 | coding | upstream | 50921 | 34937548 ~ 34951865 (+) |
| XLOC_002265 | nbeaa | coding | upstream | 267791 | 34426256 ~ 34734995 (+) |
| XLOC_002264 | stard13a | coding | upstream | 598018 | 34315719 ~ 34404768 (+) |
| XLOC_002263 | NA | coding | upstream | 762948 | 34239060 ~ 34239838 (+) |
| XLOC_002269 | NA | coding | downstream | 42809 | 35054311 ~ 35058561 (+) |
| XLOC_002270 | nsun5 | coding | downstream | 141426 | 35152928 ~ 35163612 (+) |
| XLOC_002271 | NA | coding | downstream | 224846 | 35236348 ~ 35242028 (+) |
| XLOC_002272 | styxl1 | coding | downstream | 246149 | 35257651 ~ 35262368 (+) |
| XLOC_002273 | tmem120a | coding | downstream | 253581 | 35265083 ~ 35275350 (+) |
| XLOC_002260 | BX548044.3 | non-coding | upstream | 782545 | 34175468 ~ 34220241 (+) |
| XLOC_002261 | NA | non-coding | upstream | 809480 | 34190542 ~ 34193306 (+) |
| XLOC_002259 | BX548044.2 | non-coding | upstream | 831361 | 34151286 ~ 34171425 (+) |
| XLOC_002277 | NA | non-coding | downstream | 358090 | 35369592 ~ 35414277 (+) |
| XLOC_002282 | BX663516.1 | non-coding | downstream | 633217 | 35644719 ~ 35644798 (+) |
| XLOC_002283 | dre-mir-132-2 | non-coding | downstream | 633515 | 35645017 ~ 35645135 (+) |