XLOC_022757 (mastl)


Basic Information

Item Value
gene id XLOC_022757
gene name mastl
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007135.7
NCBI id CM002908.2
chromosome length 42172926
location 5893134 ~ 5908241 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00045263
caaatttcaaaacaaacttgTCGCGGCTGTCAACAACAAGTGAGAATGGATGCGGTGGACTGAAAGGAAGACTCAACAAACAAATAACGTAACAGtctaaataaatgtagcctttaCATGCATTCATGGTGATTTGTGTTTGATTTCCAACACAATAATCACCATTAAAACGTTTTTGCGTGTATCTGAATGAGGAACGCCTGACTGCACGGAAACACAAACGACCACTTACGTTAGTGGACTTACCATCAGCCAgttgtattaaattaatatttttttagagaTGGAAGCTCGTGGATTGGCATGCGAAAGCTCAAACAGTGCAGTGAAAGCTCCTTCCATCGAGGACTTCGTGCTCGTCAAACCCATCAGTCGAGGAGCTTTCGGGAAGGTTTACCTCGCCAGAAAGAAATGCAACTCCAAACTCTATGCCATCAAGgtggTGAAGAAAGCAGAAATGGTGGATAAGAACATGACTGAGCAGATGAGAGCTGAGAGAGATGCTCTGGCTCTCAGTAAAAGCCCTTTCATTGTGCATCTGTTTTACTCCCTTCAAACCGCAACTAAAGTCTATCTGGTGATGGAGTATCTGATTGGAGGAGATGTGAAATCGCTTCTTCATATTTATGGCTACTTTGATGAGGACATGTCTCTGAAATACATCTCAGAGGTCGCGCTCGCACTGGATTACCTTCACAGACACAGCATTATTCACAGGGATTTAAAACCAGACAACATGCTCATCTCGAACGAGGGTCACATTAAGCTTACAGACTTTGGCCTCTCCAAGGTTAAACTCGACAGAGAGCTAAACCTGATGGACATTTTAACCACACCATCTTTGGTGAAGCCTACAAAGGATTATTTTCGAACACCAGGTCAAGTTCTGTCACTGATCAGCTCTCTTGGTCTTAACACCCCAGTTATAGAGGGTAAGCGTCACAGCAGCACAGTACTGGGCAGCCCAATGTCCTGTGGGAAAGTCAAGCAGAGGAACAGGTCTCTGGGCTCACCTCTCATGAAGAGACGGGCCGAGTACATGAATTCCCCAGTGTGCACAAGTCGAGCTCTAGCATCCAACAGTGTGTTCAGTCCTGTCCTGCTGGCGAGGAGTTTGACACCAAGGCTGTTAAAGTCAGGGAAGAGACTCGATACTATGAGTGTTGGGagcacacactcatgcatgctACCATCCACTACTGACTCTGAAAACTGCGTCAGCCCTATGTGGGAAGATGAGCAGAACTTGCATGATGTCGAGAACATTCCACAGCTGAATGGAAGAGAAGTTGACAACAGAAAGTCAAGAAACGTTCCCTTGACTCCTGTGGAAAAGAGGAAGACGCTTCCAGCGCGAGTTCAGGATCACAGCACTGTTTTTACTCCCCTCAATAACCAAGTTAACAACAGCAGGAATATTAAACCAGACCTTTCTGCAAAAAGGCTCCAGTTTGGTGCAACTGACAACTCTGCCACTAAATTGGAGAAGACTGTTCCTCATCAGTCAGTTGGGAATGGTCTTATAAAACCAGAGCCTCTAAAAGAGCTCAAATCTTCAGTGAAGAGAACATTTGAGGAGGTTGAGAAAAGCCCAGAACAGGCTGAGATTTTATGCAAGAAAAATGACGCAGCGTACAAGAGATCCTTCCAGATTCCTGAGAAGACCTCAAGGGCCCACACAGGCTTGACTGGAATTTTCTCGATTGTAGGGCTTGACGATGTTAAAAGTGCACCTAAATGTCAACAGTTCAATGAGAGAACTGGCCCAAAGCAGTCTAGTCCCATAGCTGTGGCCAAAAACCTCTTCTGTGAACTGGAAGATCAGGGGGAAGAGGGGGGTAAAGCAGAGCCCAACTCCAGCTCTTCAACCTCGCCCGGTGATGAGCGAAACATCAGAAGAAGCCTAAGTTTAGAGTCTGACGTCTCAGCACATGAGATGTCACTGGTTGCTAACACGCCACAAAAACTGTCAGACGCCAAACAAGAAGTTTTATCTTCGTCTTTTGAGGAGTTGGACGAAAACGAGATTTCTGCAGTCACCCCGATGGCCAGACCCACGGTTGCTACACCAAAGCATAGCAGCGCAAAGCAGCGCAGGGGTGAATGTGAGCGTTCTCTGCTTGATCATCCTCATGGCCTGTCTGACAGTATGATCAAATCACCCGGCTTCCTCAAACCCAAAAATGTGGTTGCGTTTAGGAGCTACTGTAGCTCAATCAACCGCTCATGTACGTCACATCTCAGCCTGGCCTCGTTTGATGCCATGGAAATGTCTGCGTCAGCGTCCTTTCACAACGCTGTGACTCCAGTTCAGAAGAAAAGGCCCAGTCTAAACAACTCTCTTTACCAGACTCCCCAGCAGATGGTTGTGTCTCACACTCCCTATAGGACACCTAAAAGTGTCCGTAGAGGTCCTGAACGTGTTGAAGGGGCTCCTATTTTGGGTACTCCTGACTACTTGGCACCAGAACTTTTATTAGGCAAGCCTCATGATTTCATGGTGGACTGGTGGGCATTGGGTGTTTGTCTGTTCGAGTTTCTCACGGGAGTCCCACCTTTCAACGATGAGACCCCTCAATTGGTGTTTCAGAACATTCTCAACAGAGATATACCATGGCCAGACGGAGAAGAGGAGTTGACTCCAAATTCAAGAAATGCCATTGAGATTCTGCTCACCATGGACACACTCAAACGGGCCGGCTTAAAAGAGTTGAAGGATCACCCGTTTTTTGATGGTGTGGACTGGGAAAACCTACACCATCAGACGATGCCCTTCATCCCACAGCCTGACAACGAGACTGACACATCGTACTTTGAGGCCAGGAATACGGCACAACATCTGACCGTTTCCGGCTTCAGTCTCTAAGCACAACGTGGAGACGCGGTTTGCTCAGAACTGTTGTTGAGGATCCCATCATGCTCTTCCAttctttgttttgtcttttggtttttcatgtcaaatattttatgtgactttatttctgtatttcagtCAGGTGGCTTTTTATTTACCGACAGTATATGCACATACATGCTGCCAGATGGCCCATTCGTTATCggaaaaagtaatatattatgtAA
>TCONS_00045264
AAAAATCAACTTATCATCGCTGCTATCACTGCTGTATAATAGTGGTCACTTTCTAACGTGTGTTCTAGAATGTTGTGCATTTAGTAATCTGAgcttgagtcttttttttttttttgctttctgacAGATTTCATGGTGGACTGGTGGGCATTGGGTGTTTGTCTGTTCGAGTTTCTCACGGGAGTCCCACCTTTCAACGATGAGACCCCTCAATTGGTGTTTCAGAACATTCTCAACAGAGATATACCATGGCCAGACGGAGAAGAGGAGTTGACTCCAAATTCAAGAAATGCCATTGAGATTCTGCTCACCATGGACACACTCAAACGGGCCGGCTTAAAAGAGTTGAAGGATCACCCGTTTTTTGATGGTGTGGACTGGGAAAACCTACACCATCAGACGATGCCCTTCATCCCACAGCCTGACAACGAGACTGACACATCGTACTTTGAGGCCAGGAATACGGCACAACATCTGACCGTTTCCGGCTTCAGTCTCTAAGCACAACGTGGAGACGCGGTTTGCTCAGAACTGTTGTTGAGGATCCCATCATGCTCTTCCAttctttgttttgtcttttggtttttcatgtcaaatattttatgtgactttatttctgtatttcagtCAGGTGGCTTTTTATTTACCGACAGTATATGCACATACATGCTGCCAGATGGCCCATTCGTTATCggaaaaagtaatatattatgtAACACTACTATAGATATCGACTCTTTAATGCACATTTACACTCAAGGCACTGAAGACACTGCTGTTTTACTCTAGTTTTCATGAAAACTATACTTGTCGGGCTGAAATTTTAACATGCTAAATGTTTTAACTAGTCTTAAAGCAAGTACGATTGCTGCTtcaaaaacatttctttattcattaatcatttaatgtGTACACAACACCTTTAAACACATCCGTGGTTTATAATGTTACCTGTTTTAAAATGATTCTAAAAGGGCttcctgttaaataaaataaaatacaactattgc

Function

symbol description
mastl Predicted to enable protein phosphatase 2A binding activity and protein serine/threonine kinase activity. Acts upstream of or within thrombocyte differentiation. Predicted to be located in centrosome and cleavage furrow. Predicted to be active in nucleus. Is expressed in somite. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human MASTL (microtubule associated serine/threonine kinase like).

GO:

id name namespace
GO:0018105 peptidyl-serine phosphorylation biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0000086 G2/M transition of mitotic cell cycle biological_process
GO:0002574 thrombocyte differentiation biological_process
GO:0006974 cellular response to DNA damage stimulus biological_process
GO:0006468 protein phosphorylation biological_process
GO:0007049 cell cycle biological_process
GO:0051301 cell division biological_process
GO:0032515 negative regulation of phosphoprotein phosphatase activity biological_process
GO:0016310 phosphorylation biological_process
GO:0005813 centrosome cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0032154 cleavage furrow cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0051721 protein phosphatase 2A binding molecular_function
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG:

id description
ko01001 Protein kinases

ZFIN:

id description
ZDB-GENE-040801-128 Predicted to enable protein phosphatase 2A binding activity and protein serine/threonine kinase activity. Acts upstream of or within thrombocyte differentiation. Predicted to be located in centrosome and cleavage furrow. Predicted to be active in nucleus. Is expressed in somite. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human MASTL (microtubule associated serine/threonine kinase like).

Ensembl:

ensembl_id ENSDARG00000055566

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00045263 False 3081 mRNA 0.46 12 5893134 5907947
TCONS_00045264 True 1010 lncRNA 0.39 3 5905548 5908241

Neighbor

gene id symbol gene type direction distance location
XLOC_022756 trpc1 coding upstream 23512 5840258 ~ 5869622 (+)
XLOC_022755 si:ch211-157j23.2 coding upstream 54810 5826005 ~ 5838324 (+)
XLOC_022754 si:ch211-157j23.3 coding upstream 68666 5811350 ~ 5824468 (+)
XLOC_022753 si:ch211-157j23.2 coding upstream 83111 5799764 ~ 5810023 (+)
XLOC_022752 si:ch211-157j23.3 coding upstream 94710 5789582 ~ 5798424 (+)
XLOC_022758 pimr64 coding downstream 4394 5912635 ~ 5918755 (+)
XLOC_022759 abi1a coding downstream 27136 5935377 ~ 6012786 (+)
XLOC_022760 CR385039.1 coding downstream 155430 6063671 ~ 6063785 (+)
XLOC_022761 NA coding downstream 174419 6082660 ~ 6089253 (+)
XLOC_022762 si:ch211-37e10.2 coding downstream 199660 6107901 ~ 6118349 (+)
XLOC_022748 NA non-coding upstream 925885 4960973 ~ 4967249 (+)
XLOC_022747 NA non-coding upstream 1384544 4504746 ~ 4508590 (+)
XLOC_022744 CU462914.1 non-coding upstream 1736735 4154959 ~ 4156399 (+)
XLOC_022743 CT583636.1 non-coding upstream 1833561 4059456 ~ 4059573 (+)
XLOC_022741 NA non-coding upstream 1933711 3958172 ~ 3959423 (+)
XLOC_022764 NA non-coding downstream 481194 6389435 ~ 6399785 (+)
XLOC_022765 BX120013.1 non-coding downstream 496953 6405194 ~ 6405316 (+)
XLOC_022766 CR790361.1 non-coding downstream 673811 6582052 ~ 6582168 (+)

Expression


Co-expression Network