XLOC_025544 (prkcbb)


Basic Information

Item Value
gene id XLOC_025544
gene name prkcbb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 35005062 ~ 35266060 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050337
CTGTTTTATGTGTAACTGGCTTGTACTCATGCCAGTTTAATCAATGATCGAGGACTTTTAGTTACctgaattatttttcatattcacTCATgtccttttattttttcttacaaGCTATGCAAATTAAAGTACCGTTTTGGTGCGTTTTGTACAACCGGTCATGTGATGTCAACATGTAAAATGCCCATGAGGGGGCGACCCGCTCCATGCAGAATAAAATCACCCTTTTTCCCCCAGCACTTATCTTTATCTCTCATGGCAGTAAATGTTTATAACGTTATCTCTAAAACCTAAACGCTTTGTTTAAGAGTAGAACagtttaattacaaaaaataaataccgactgcacctttaagtttgaACCCAAATAGGCGTTCATCCGACCTACTCCATATTCAGTATCAACAAGGCAGCATGATTGGCAGATTCCCTTCAATTATAAATGTTCACGAGCCTCATAATTCATCAGCTCGTAAATGTTTCCACACTGTCTCCTTCTCGTAATGCTGTCGAGCGGATTTTAATGTAAATGCGTAAGAGGTTTGACAGAATCTCTATCAATCAGCTCTGCTCGCCAAAGGTAAATGAGTGGGAGGGTGGGAGGAGTCTTGTAACAGCGCGTCAGTGTGTGtctgggtatgtgtgtgtgtgtgtgtgaaaagagagagagagagtgtaccGGTGAAGGCACTTGGGCGGAGAAGGAAGCGAAGCATCGCGCCTGAGAGTTGATCGCAGTCTGAAGCTTTTGCGTTACATGTGCGCAACTCACTCCAGTGTCCAGGCTCGTGCAAACTTTCCCCGCTTTTAGAATGGCAGAGCCGGCGAACAGCGATGGAGAGGAGAGGAGCGCACCCATGAGGGGTTTTGCCCGGCAAGGCGCCCTGAGACAGAAGAACGTTCACGAAGTCAAGAACCACAAGTTTATCGCTCGCTTCTTCAAGCAGCCTACTTTCTGCAGCCACTGCACGGACTTTATCTGgggttttgggaaacaagGATTTCAATGTCAAGTCTGCTGCTTTGTGGTGCACAAGCGTTGCCATGAATTCGTCACCTTCTCCTGCCCGGGAGCAGATAAGGGTCCCGCATCAGATGACCCGCGCAGTAAGCACAAGTTCAAGGTCCACACATACTCCAGTCCGACCTTCTGTGACCACTGCGGCTCTCTGCTGTACGGCCTCATCCACCAGGGCATGAGATGTGACCactGCATGATGAACATCCACAAGCGCTGTGTGGCCAACGTGCCGAGTCTGTGTGGGACTGACCACACCGAGAGGAGGGGCCGCATCCAAATCACTGCAGAGATCAAGAACAATGTGCTCACCGTCAGCATTAAAGAGGCAAAGAACCTGGTACCCATGGACCCCAATGGCCTCTCTGACCCCTACGTCAAACTAAAACTCATCCCTGACCCCAAGAGCGAGAGCAAACAGAAGACCAAGACCATCAAGTGCTGCCTGAATCCCACATGGAACGAGACCTTCACATTTAATCTGAAGGAGTCTGACAAGGACCGCAGGCTGTCTGTGGAGATCTGGGACTGGGACTTGACCAGCCGGAACGACTTTATGGGCTCTCTTTCTTTTGGCATTTCAGAGCTTCAGAAGCAAGGAGTGGACGGATGGTTTAAGCTGCTCAGTCAGGAAGAGGGCGAGTATTTCAATGTACCTGTCCCACCTGAGGGAGAAGAGGGCAACGAGGAACTCCGACAGAAGTTTGAGAGAGCTAAAATCGGTCCCAGCAAAACAGATGGCTCCTCCTCTAACGCCATCTCCAAATTCGACAGTAATGGCAACCGGGACCGCATGAAACTGTCTGACTTCAATTTCCTCATGGTTCTAGGAAAGGGTAGCTTTGGAAAGGTAATGTTGGCTGAGAGGAAGGGAGCGGATGAGCTGTTTGCCATaaagatcctgaagaaggacgtGGTGATCCAGGACGATGATGTCGAATGCACTATGGTGGAGAAGAGAGTGCTGGCTTTGTCAGGAAAACCCCCGTTCCTAACCCAGCTGCACTCCTGCTTTCAGACAATGGACCGCCTGTACTTTGTCATGGAATACATCAACGGTGGAGATCTCATGTACCATATCCAGCAGGTCGGCAAGTTTAAGGAGCCCCATGCTGTgtttTATGCTGCAGAAATTGCCATAGGCCTGTTCTTCCTGCATTCAAAGGGTGTTATTTACAGAGATCTGAAGTTGGATAATGTCATGCTGGATGCAGAGGGTCATATCAAAATCGCTGACTTTGGCATGTGCAAAGAGAACATGCTTGATGGAGTCACCACCAAGACCTTCTGTGGAACCCCTGACTACATCGCCCCTGAGATCATCGCCTACCAGCCGTATGGAAAGTCAGTGGACTGGTGGGCTTTTGGAGTTTTGCTATATGAGATGCTGGCTGGGCAGCCTCCGTTTGATGGCGAGGATGAGGATGAGCTATTTCAGTCCATCATGGAGCACCATGTTTCCTATCCCAAATCCATGTCCAAGGAGGCTGTGGCCATCTGTAAAGGGCTGATGACCAAACACCCAGGCAAGCGTCTGGGCTGCGGTCCAGAAGGTGAGCGAGACATCAGGGAACATGGCTTCTTCCGTTACATGGACTGGGAGAAGCTGGAGCACAGGGAAGTTCAGCCACCATTTAAACCAAAAGCCCGGAACAGCCGAGATACCTGCAACTTTGACCGGGAGTTCACAAAAATGGCCGTGGAGCTAACGCCCACCGACAAGCTGTTTATCATGAATCTGGACCAGGACGAGTTCCTGGGCTTCTCCTACACCAACCCAGAGTACGAGGTTCCTGCTCAGGGTTAATCGAGCAAGCATACTGGAGACTGCTGGCCATGtatctctctgtctgcctgtatgtgtgtgacaTGTATGCTCAGGGTCGTGAAAGCTCACTCATATTACTGTAACAGGATTTAACCAAAGGGCTCAGGTGGACCACCTCAGTATACAGCTGTGCGGTATCCGACGCATTTCCAAAGGGGGCCAGAAATCAGTCTCAGCGTAATGTTTCCCTCTTCCTGGCGTTCACACAGAGCCGGTAGCCCTCcagcttatttatttttattttttgagactGCATTGTTGGTGTTTATACGACGGTAAACGCGGCCTATGCAACAAACGAGGAACAAACCCCGAGTGAGCAATTTGAAAAACAACAATGCCGCCTTCAATTATTTATTTGCGCTTCATTATTTTTCCCCCCGTTTGGTTTCTATTTGAGCTGAGCTAATGTTTAATTCACTGGCTTAAACCCATTATACCAAAATATTATTACCTCCCACACATGACTTGAGCCGCCGCTCCCGTACGCAGCCTGAATCCCTGGCAGAAGTGTCCTCACTATTGTGACATTCAGGGAGAGGGAAAGAGAAAGACGACAAAGAAAAAAATGGTCATTATCATTCATAACTCTGTATTTCAGGAAGGATTCATATCACTGGGTTTGGGAAGAGTGGAGATTTGTAAAGCTACTAGTTCATATTCCAGTATCCTTCAGGACGAGGATTAGAAACAGCCGGATAGATCAAACGCAGTCGACGCCGTCGTGCAATACAGAATTCTAATAGTACATAACTGTGTATCTATGCACCTTGTAGGAAACACAATgtgccatttcttttttttttccaaaggacTTCGTCGTCCCTGTGATTTCAAATGCTTAATTTGCATGATTGCAATAGTTTGTTTATCCTCTAGGCATAATACTTTCGGACGTATCTATCATTCAAGCGGAAAAAAAAGACTTCAGACGTGAGGTTTTCAATCACAGAACAATCATACATGCGTTTCTGAATGCTTGGTCTAGACCGGTCGTATATAGCAATGTGATTCGAGTCTGCCACCTATGTGCACTCATAGGCTTTGTGTATATAATGTAACTATAAGCACTTTCTGAAATGACATGTATTTCTTAGCACAGTAAAAAGATAAAGGCGTAAGGTTTTTGCATGTTCAGATGTATTATCACTACGCGTTAATGGCTTGTAATTTGTTCCTCGCATCATTATGTTTTCTAGTACTCATGCATCTCAAAGTTACCTGGTGAAACCTCTAATGAAAATTACTTTGAGATTAGATAAACATAAATCGATAGCCTTCTCTCTCCGGAATAAGCGGCGCTGGATTGATCCGTTCTGCCCGTTTTTGTACAGATCTTAACCTCTTTAgtgctgtgtgtgagtgtgtgtatgtatgtatgtatgtatgtgtgtgtgtgtgtgtgtgtgtatatagcgGTGCTGTCTCTGTGAGGTGAATAGTCGCAGTGTTTTGGCTAGCCTTCATTTTATACCCGCCGTGTGGCCACCGGTAGTGCTATCCCATAATGCTGCACGAGACCCAGACCAAGCTCCGTTGAACGTTAAGCCGGCGCGTATTGATCGGACAATTatcaaaaagagaaataaaaggCGTATATCAGTTGACACTTTAGAGCGTGGGGTGAGCGCGAGGTGATTTAGAGGGAAAATTTAGCAGGCTTAAAGGCACACAGTGTCTGGTTAATTGCCAACCAAACAGTTTATGTTTCTCTCGGAGGTCAGGCTCCAGGGATAAAGGATTGCGAGGTCTCTGAAGCCACCAACACATAGATAACAGGGTGAGATGCTAGGTACAGTGTTAATGCTATAACTTATTGATGTATTTATGAGAGAATATGTAATTTGTTCTATTTATAATAAAGATATTCAATGTAAACCTGCTTT
>TCONS_00050338
agagagtgtaccGGTGAAGGCACTTGGGCGGAGAAGGAAGCGAAGCATCGCGCCTGAGAGTTGATCGCAGTCTGAAGCTTTTGCGTTACATGTGCGCAACTCACTCCAGTGTCCAGGCTCGTGCAAACTTTCCCCGCTTTTAGAATGGCAGAGCCGGCGAACAGCGATGGAGAGGAGAGGAGCGCACCCATGAGGGGTTTTGCCCGGCAAGGCGCCCTGAGACAGAAGAACGTTCACGAAGTCAAGAACCACAAGTTTATCGCTCGCTTCTTCAAGCAGCCTACTTTCTGCAGCCACTGCACGGACTTTATCTGgggttttgggaaacaagGATTTCAATGTCAAGTCTGCTGCTTTGTGGTGCACAAGCGTTGCCATGAATTCGTCACCTTCTCCTGCCCGGGAGCAGATAAGGGTCCCGCATCAGATGACCCGCGCAGTAAGCACAAGTTCAAGGTCCACACATACTCCAGTCCGACCTTCTGTGACCACTGCGGCTCTCTGCTGTACGGCCTCATCCACCAGGGCATGAGATGTGACCactGCATGATGAACATCCACAAGCGCTGTGTGGCCAACGTGCCGAGTCTGTGTGGGACTGACCACACCGAGAGGAGGGGCCGCATCCAAATCACTGCAGAGATCAAGAACAATGTGCTCACCGTCAGCATTAAAGAGGCAAAGAACCTGGTACCCATGGACCCCAATGGCCTCTCTGACCCCTACGTCAAACTAAAACTCATCCCTGACCCCAAGAGCGAGAGCAAACAGAAGACCAAGACCATCAAGTGCTGCCTGAATCCCACATGGAACGAGACCTTCACATTTAATCTGAAGGAGTCTGACAAGGACCGCAGGCTGTCTGTGGAGATCTGGGACTGGGACTTGACCAGCCGGAACGACTTTATGGGCTCTCTTTCTTTTGGCATTTCAGAGCTTCAGAAGCAAGGAGTGGACGGATGGTTTAAGCTGCTCAGTCAGGAAGAGGGCGAGTATTTCAATGTACCTGTCCCACCTGAGGGAGAAGAGGGCAACGAGGAACTCCGACAGAAGTTTGAGAGAGCTAAAATCGGTCCCAGCAAAACAGATGGCTCCTCCTCTAACGCCATCTCCAAATTCGACAGTAATGGCAACCGGGACCGCATGAAACTGTCTGACTTCAATTTCCTCATGGTTCTAGGAAAGGGTAGCTTTGGAAAGGTAATGTTGGCTGAGAGGAAGGGAGCGGATGAGCTGTTTGCCATaaagatcctgaagaaggacgtGGTGATCCAGGACGATGATGTCGAATGCACTATGGTGGAGAAGAGAGTGCTGGCTTTGTCAGGAAAACCCCCGTTCCTAACCCAGCTGCACTCCTGCTTTCAGACAATGGACCGCCTGTACTTTGTCATGGAATACATCAACGGTGGAGATCTCATGTACCATATCCAGCAGGTCGGCAAGTTTAAGGAGCCCCATGCTGTgtttTATGCTGCAGAAATTGCCATAGGCCTGTTCTTCCTGCATTCAAAGGGTGTTATTTACAGAGATCTGAAGTTGGATAATGTCATGCTGGATGCAGAGGGTCATATCAAAATCGCTGACTTTGGCATGTGCAAAGAGAACATGCTTGATGGAGTCACCACCAAGACCTTCTGTGGAACCCCTGACTACATCGCCCCTGAGATCATCGCCTACCAGCCGTATGGAAAGTCAGTGGACTGGTGGGCTTTTGGAGTTTTGCTATATGAGATGCTGGCTGGGCAGCCTCCGTTTGATGGCGAGGATGAGGATGAGCTATTTCAGTCCATCATGGAGCACCATGTTTCCTATCCCAAATCCATGTCCAAGGAGGCTGTGGCCATCTGTAAAGGGCTGATGACCAAACACCCAGGCAAGCGTCTGGGCTGCGGTCCAGAAGGTGAGCGAGACATCAGGGAACATGGCTTCTTCCGTTACATGGACTGGGAGAAGCTGGAGCACAGGGAAGTTCAGCCACCATTTAAACCAAAAGCCTGTGGCCGGGATGCAGAGAACTTTGACCGCTTTTTCACCCGCCATCCACCGGTTCTCACCCCTCCAGACCAGGAGGTCATCATGAACCTCGACCAAGACGAATTCGAGGGCTTTTCCTTCATAAACCCTGAATTCCCTGCCATGGAAGCCCAGAGTTAAGGGCGACCCCCTAAAACTAACCCAACCCTCCATCAACCCTCCCCTGCCCTCTTCATCAAACCTCATGTTTATGTACCATACACTGGGGCACGTGTATGTATATAAACAGCCATGCACCAAAACTAAATCATCAATATACGTATGCATGCTGAGTTTCGATATTCGTAGATTAGCCTAAAGATCGCTGTGGCTTTCACGACATCCCATTGAATGTATTCATGCTGGAGGAACGTTTGAATCTTTAGACCTTCTCGCACTTTGGCTGTCTTTATACTATTTGTTCTCCTACGGCTTTCCTGAATGTGGTGTGTATTGCATAGCTCTCTTCTAGACTACCTTCGGATTTGTCTTTCTTGGGATTGTCGGTGTTGAGATTTAGCCATTTGCACTAAAGGTGCATGAATCACATATATGAGATGCAAAATGGCTAGCCTCGCTCTCCTTATCCAGCCTGCGGCAGTGATATTTTTTGCTGATTTTATCATCAAACCATTTTGCTTGTTTCCAAAAGAATGCAAACCTGGAAAGGTTTTTGCATGATGATTTTGTTTTGTCCGATATGTTAGTTAGTTAGCTCTATAGTGAACTCGAGGCTTGTTTTAATCTTTAGTACAGAATCTAACCGAATTTTTTCTCTTCATTTAAAGCATGAGTAAATCTGAATGAATTAGGGTGCCTGTTTGCGTGTATGTACAGGCCAATAGAGCTTAATGGATGTGCCTGATTGTGGTAGTGAtctgcctttctttctttttttttttttgcctgatcATCTCACACCATCTGCAAACATTCACCCATGTATGGAAAGCATGACTCCTGTGATGGTTCCTCTTCCTTGACTTCTGCTTAAAGGTCAGACGGATTTTATCGAAAGGTATTTGACAGGCATATTAAATATCAACTACCTCCTGCTAGAGACAATTACCGATTGAAATAGGATGAGAGAACGAGTGCTAATTTCAGAATTAAGCTTGCACTGTAGCTAGTAACCTTTAAAAGCCCATCAGCCGTATATTACTGACCTCTATCTTAGATAGGAATAGAAACCACTTTTAAACATTCTTGGGGGTTTATGATGACAAAGAGATGAGTAGTTACCCAAGGGTAATATCTCAAATTATACCCTGAATTTCTTTCAGGAGCTCATGTATGAGCAAATTAGTCTAGTTGGGACGCGTTGATGTAGCTTTACTTCGCCTGAATGATTCCATCTTGAAGCTTGTCAACAGAGACCGGCCTAGTGTCGGTACGTGAGTTTGTGTGGAACTTAATATCGCGCCTCAAAGCTGAACAGGATATAAAGACGATGAAACATTAGAATTAAACTAGTAACATAAAGCATTTTAAGCGTGTAAACATTGCTCATAAGCAACAATAGGGGTCGGATGAAGCTATCTGACTTCGTGTTAATGGGTCCAACAGGGGGGCTGGTCAGTGCAGAGCCCTAATTTAGCATTCTGACGGCTCGGGATACGACAGCACTGTTCATGTCAGCACTAACAGCAGCAAAGTCCTTGTGTGGAACAGATACTGTATCACTAAATGGAACTGGAAAGGCCACAAGAGCCACACATCCACAGAAACGGGTCAGATCCTCTCAGACATCACAGTTCCTTGAGCGGTTATCCGTGCTGACTAGCGGCCAGTGGCTTTTATTGGAAACCACTGGGGCTTCATATCATATCTTCATCATGGGATTTCAGAGAAGGGAGAACCTCTTTAAAATGGCTTCTTGTGCAAGAGGGTTTCCAGATATATACTGCGGGATTAGAAAACTGAAAGAgatgaaaaagggaaaaaaaatgttgtgcaTTTGTCATTTCTGCCAAATAGTTATATACAACAAGCAGTTCAACATAGggctttgatatttttttaagtgtcttaaaataatataagcaaATAATATGTGTCAAATGTTCTTAAATGTTATGAATTCTATGTGGTCAGTATTGTAGATAACGAAAAAATTCAAGAAAAAAAGGGGGTTTTGTGTTTGTGCATAGCAGCTTTGTGCATGAACTGATTcagagtacttttagcttagtgTTTGTGTTCTTGACATTCCTGTGTGATTTGCTCAATACATCCTCAATGCTTTTTTATGTGCCAAAtattttccacacacacacacacaaaacatgaacatacattcaaataaaagtgaaacatCAATAGCC

Function

symbol description
prkcbb Predicted to enable several functions, including androgen receptor binding activity; histone kinase activity (H3-T6 specific); and nuclear receptor coactivator activity. Acts upstream of or within blood coagulation and embryonic hemopoiesis. Predicted to be located in nucleus. Is expressed in brain; retinal neural layer; and somite border. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and lung non-small cell carcinoma. Orthologous to human PRKCB (protein kinase C beta).

GO:

id name namespace
GO:0002250 adaptive immune response biological_process
GO:0018105 peptidyl-serine phosphorylation biological_process
GO:0006325 chromatin organization biological_process
GO:0006915 apoptotic process biological_process
GO:0042113 B cell activation biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0007596 blood coagulation biological_process
GO:0002376 immune system process biological_process
GO:0006468 protein phosphorylation biological_process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling biological_process
GO:0035162 embryonic hemopoiesis biological_process
GO:0016310 phosphorylation biological_process
GO:0050853 B cell receptor signaling pathway biological_process
GO:0005634 nucleus cellular_component
GO:0016020 membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0030374 nuclear receptor coactivator activity molecular_function
GO:0042393 histone binding molecular_function
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003682 chromatin binding molecular_function
GO:0050681 androgen receptor binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0035403 histone kinase activity (H3-T6 specific) molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004697 protein kinase C activity molecular_function
GO:0004698 calcium-dependent protein kinase C activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1178 Predicted to enable several functions, including androgen receptor binding activity; histone kinase activity (H3-T6 specific); and nuclear receptor coactivator activity. Acts upstream of or within blood coagulation and embryonic hemopoiesis. Predicted to be located in nucleus. Is expressed in brain; retinal neural layer; and somite border. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and lung non-small cell carcinoma. Orthologous to human PRKCB (protein kinase C beta).

Ensembl:

ensembl_id ENSDARG00000022254

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050337 False 4732 mRNA 0.46 17 35005062 35266060
TCONS_00050338 True 4340 mRNA 0.46 17 35005730 35250525

Neighbor

gene id symbol gene type direction distance location
XLOC_025543 smarce1 coding upstream 10000 34985895 ~ 34995062 (+)
XLOC_025542 ca10b coding upstream 23389 34919810 ~ 34981673 (+)
XLOC_025540 itga3a coding upstream 88021 34846201 ~ 34917041 (+)
XLOC_025541 BX890565.1 coding upstream 94663 34910280 ~ 34910399 (+)
XLOC_025539 cdk5r1a coding upstream 182742 34821327 ~ 34822320 (+)
XLOC_025545 cacng3b coding downstream 32018 35298078 ~ 35375978 (+)
XLOC_025546 rbbp6 coding downstream 140335 35406395 ~ 35421194 (+)
XLOC_025547 NA coding downstream 173850 35439910 ~ 35489947 (+)
XLOC_025548 tnrc6a coding downstream 229510 35495570 ~ 35533366 (+)
XLOC_025549 rpusd1 coding downstream 276007 35542067 ~ 35549478 (+)
XLOC_025429 BX649540.1 misc upstream 4756026 30248739 ~ 30249036 (+)
XLOC_025538 NA non-coding upstream 271944 34732869 ~ 34733118 (+)
XLOC_025535 BX470190.1 non-coding upstream 645730 34359215 ~ 34359332 (+)
XLOC_025534 NA non-coding upstream 751116 34253557 ~ 34253946 (+)
XLOC_025533 NA non-coding upstream 754819 34249182 ~ 34250243 (+)
XLOC_025550 NA non-coding downstream 301442 35567502 ~ 35570748 (+)
XLOC_025552 BX572621.1 non-coding downstream 477124 35743184 ~ 35743256 (+)
XLOC_025553 NA non-coding downstream 483781 35749841 ~ 35750233 (+)
XLOC_025555 NA non-coding downstream 692618 35958678 ~ 35965512 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000046_05904400_05973821 PRKCB, PRKCBB coding CI01000046 null 5904400 ~ 5973821 (+)
bowfin (Amia calva) AMCG00018469 prkcb,LOC107722959,LOC105899995 coding CM030135.1 CM030135.1 11755834 ~ 11817048 (+)