XLOC_037672 (umps)


Basic Information

Item Value
gene id XLOC_037672
gene name umps
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 11576502 ~ 11587070 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00073974
ACGTCACTACAAGCCCGCCAGGAAAAAAATGCACAGCACATTGCGGTGAATACTTCATTCTGGTTAGTGAAACATAACTTGTCCAGCAGGAATGGATGACACTAGTCTTGATAGTTTAATCCTAAAACTCCACGACATCCAAGCCGTGAAATTCGGTACTTTTAAACTAAAAAGTGGACTTTCTTCACCGATCTATTTTGATCTCCGAGTAATAGTGTCTCATCCAGCGTTGATGAATCAGGTGGCGGATCTACTGCATAAGAAATCTGAGGAGGCAGGAGTGCAGTTTGACAGTGTGTGTGGAGTCCCTTACACTGCTCTTCCTCTGGCCACAATCATCTGCTCCAGCAAACAGTACCCCATGCTCATCAGACGAAAGGAGGCGAAGGACTATGGAACGAAGCGTCTCATCGAGGGAACCATCCGCCCTGGTGACAGATGTCTGATAGTGGAGGATGTTGTGACCAGCGGCAGCAGTGTCCTAGAAACCGCTGAGGTGCTTGAGAAAGAGGGTCTGAAGATCACAGATGCCGTTGTGTTAATGGACAGAGAGCAGGGTGGCAGCACCAGGCTTGCTGACAGCGGAATCACTCTACATTCAGTCATTTCCATCTCCAGACTTCTGGAAGTGTTACTCAAAGCTGGCCGAATTGACACGGACACCGCTCAGAGTGTCAAGAGGTTCGTTCAAGACAATAACAcctacattttaaagaaaaatggcTCCTCGGCTGCTAAAAAGAGTTGTGGTGAGCTCAGCTATGGAGCTCGGGCAGGGCTGCCAGATACTCACCCTCTTGCTGCCCGCCTGATGCAGATCATGGAGGACAAGAAGACCAACCTGTGTGTGTCTGCGGATGTGACTCACTCCAAGGAGCTGCTGGATATTGCAGTGACGTTGGGGCCTCTGATTTGTGTGTTGAAGACTCATGTGGACATCCTGGAGGATTTTACTGCGGACGTCGCCAGCAATCTGAAAGAGCTGGCTAAAAAACACAACTTCCTAATTTTTGAGGATCGCAAGTTTGCAGACATTGGGAACACAGTGAAGCATCAGTATGAGGGGGGTCTCTATCGTATCTCCTCGTGGGCACACATCATTAATGCCCATGCGCTGCCTGGTCCAGGTGTGCTGCAGGGTCTGGGTGGCGTTGGCAATCCTCTGGGTCACGGCTGTTTACTCATTGCTCAGATGAGCTCTCAGGGTTCCCTCGCAACAGGAGATTACACTCAAGCTGTGGTCAAGATGGCTGAAGACCATTCTGATTTTGTGTTTGGATTTATAAGTGGATCAAAGATCAGTGAAAAGCCTGGTATGGTTCACATGACCCCAGGAGTGCAAATGCAGACAGGAGGAGATGGGCTTGGCCAGCAGTATTCCAGCCCAGAAGATGTGATCTGCACTAAAGGCTCTGATATCATCATTGTGGGACGAGGTATTCTAGGTAGTCCAGATCGACTCAGAGCTGCAGGAGAATACAGGACGGCGGGCTGGGAGGCGTATCTGAAAAGACTCTCACTGGCCAGCTAATCAAACCTTCAGAGAAAGAGAAACTCAGGTCCAGCAGATTTACGTGTGCTTCATTCACTGCCTAGTCATTCCATCCACTTTATTACCAACCCTCCATGTTTTGTACAGTTGGTGCTATGAAGTGTTCAAACACGTCGTAATAAAAGTGTCGTTTAAAAAATGTTA

Function

symbol description
umps Predicted to enable orotate phosphoribosyltransferase activity and orotidine-5'-phosphate decarboxylase activity. Predicted to be involved in UMP biosynthetic process and pyrimidine nucleobase biosynthetic process. Predicted to act upstream of or within 'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; and nucleoside metabolic process. Is expressed in several structures, including alar plate midbrain region; central nervous system; immature eye; mesoderm; and yolk syncytial layer. Human ortholog(s) of this gene implicated in orotic aciduria and purine-pyrimidine metabolic disorder. Orthologous to human UMPS (uridine monophosphate synthetase).

GO:

id name namespace
GO:0019856 pyrimidine nucleobase biosynthetic process biological_process
GO:0044205 'de novo' UMP biosynthetic process biological_process
GO:0009116 nucleoside metabolic process biological_process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process biological_process
GO:0006221 pyrimidine nucleotide biosynthetic process biological_process
GO:0006222 UMP biosynthetic process biological_process
GO:0004588 orotate phosphoribosyltransferase activity molecular_function
GO:0004590 orotidine-5'-phosphate decarboxylase activity molecular_function
GO:0003824 catalytic activity molecular_function

KEGG:

id description
ko00240 Pyrimidine metabolism
ko00983 Drug metabolism - other enzymes

ZFIN:

id description
ZDB-GENE-040426-785 Predicted to enable orotate phosphoribosyltransferase activity and orotidine-5'-phosphate decarboxylase activity. Predicted to be involved in UMP biosynthetic process and pyrimidine nucleobase biosynthetic process. Predicted to act upstream of or within 'de novo' UMP biosynthetic process; 'de novo' pyrimidine nucleobase biosynthetic process; and nucleoside metabolic process. Is expressed in several structures, including alar plate midbrain region; central nervous system; immature eye; mesoderm; and yolk syncytial layer. Human ortholog(s) of this gene implicated in orotic aciduria and purine-pyrimidine metabolic disorder. Orthologous to human UMPS (uridine monophosphate synthetase).

Ensembl:

ensembl_id ENSDARG00000012215

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00073974 True 1696 mRNA 0.48 6 11576502 11587070

Neighbor

gene id symbol gene type direction distance location
XLOC_037671 NA coding downstream 4148 11571312 ~ 11572354 (-)
XLOC_037670 cryba2b coding downstream 16070 11554089 ~ 11560432 (-)
XLOC_037669 fev coding downstream 24798 11548233 ~ 11551704 (-)
XLOC_037668 chpfa coding downstream 313274 11245962 ~ 11263228 (-)
XLOC_037667 BX000444.1 coding downstream 729953 10845918 ~ 10846549 (-)
XLOC_037673 NA coding upstream 8917 11595987 ~ 11655031 (-)
XLOC_037674 zc3h15 coding upstream 77727 11664797 ~ 11676491 (-)
XLOC_037675 NA coding upstream 235309 11822379 ~ 11855305 (-)
XLOC_037676 znf804a coding upstream 319700 11906770 ~ 12034444 (-)
XLOC_037677 NA coding upstream 489773 12076843 ~ 12171785 (-)
XLOC_037663 NA non-coding downstream 1205877 10368380 ~ 10370625 (-)
XLOC_037651 AL954142.4 non-coding downstream 2205636 9355372 ~ 9370866 (-)
XLOC_037649 NA non-coding downstream 2287432 9286419 ~ 9289070 (-)
XLOC_037688 NA non-coding upstream 1302828 12889898 ~ 12903013 (-)
XLOC_037689 NA non-coding upstream 1358487 12945557 ~ 12948957 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000036_01417031_01422737 UMPS coding CI01000036 null 1416887 ~ 1422737 (-)