XLOC_004491 (kif22)


Basic Information

Item Value
gene id XLOC_004491
gene name kif22
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 5048044 ~ 5071836 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00008970
aataacCGTGCCGACCCGAGAGGCGCCATTGTCAAGGAGTTTATACGGAAGTAGTGATGCATTGAATtgagtaatttttaaaaaacacactcacaTTGTACCCGAGTGTGAATTATATATCGTTCAAGAACTGGATTAGCCGCTGCACAAGTGAAGAGGTTTGATGTGTTTCATGGTGAAGAGACCACACAGCAGGAGGTGTTTCTGACCTCCGTCAAGCCAATCCTCCCACACATCCTCAATGGTCAGAATGCCAGTGTCTTTGCCTACGGACCCACCGGAGCAGGAAAGACCCACACCATGCTGGGCAGTCAAGAGCAGCCAGGCGTTATTCCCAGAGCTGTAAAGGAGGTCTTCAATCTGGTTGGAGCTCAGAAAAAAGAGCAAGATGGTTGGGAGTACTCCATTGGGATGTCTTACTTGGAAATCTACAATGAAAAGGTGCTGGATCTGTTGTCCCCAGGTTCCCAGGACCTGCCCATCCGTGAAGACAAGGACAGAAACATCCTCATTCCCGGGTTAACACACACTCCTCTCTCATCTTTTGCTGATTTTGACACTCATTTCATCCCCGCGAGCCTCAACCGAACCACAGCCTCTACTAAACTCAACCAGCGCTCCAGCCGCAGTCACGCCATCCTCCTCATAAAGGTGGTGAAGTCTCAGCGTGGTCCGCCACACAGACAGCAAACAGGAAAGCTTTATTTGGTGGATCTTGCCGGTTCAGAGGACAATCGGCGCACAG
>TCONS_00008971
GTCAAGGAGTTTATACGGAAGTAGTGATGCATTGAATtgagtaatttttaaaaaacacactcacaTTGTACCCGAGTGTGAATTATATATCGTTCAAGAACTGGATTAGCCGCTGCACAAGTGAAGAGAAATGGCACAGCGTGTTGCTGTGAACGATGGAGCTGCTGGATCCAAACGCACCTCTCGTGTTCGAGTGGCCGTCCGGCTGAGACCCTACATGGACAAGCAGGACGAGAAGAGCGAGGGCTCCTGTGTGCGGGGTCTGGGGCCACAGAAGCTGGAGATCATCAACTGGAGGAACGCCACTGAGACCCTGCAGTACCAGTTTGATGTGTTTCATGGTGAAGAGACCACACAGCAGGAGGTGTTTCTGACCTCCGTCAAGCCAATCCTCCCACACATCCTCAATGGTCAGAATGCCAGTGTCTTTGCCTACGGACCCACCGGAGCAGGAAAGACCCACACCATGCTGGGCAGTCAAGAGCAGCCAGGCGTTATTCCCAGAGCTGTAAAGGAGGTCTTCAATCTGGTTGGAGCTCAGAAAAAAGAGCAAGATGGTTGGGAGTACTCCATTGGGATGTCTTACTTGGAAATCTACAATGAAAAGGTGCTGGATCTGTTGTCCCCAGGTTCCCAGGACCTGCCCATCCGTGAAGACAAGGACAGAAACATCCTCATTCCCGGGTTAACACACACTCCTCTCTCATCTTTTGCTGATTTTGACACTCATTTCATCCCCGCGAGCCTCAACCGAACCACAGCCTCTACTAAACTCAACCAGCGCTCCAGCCGCAGTCACGCCATCCTCCTCATAAAGGTGGTGAAGTCTCAGCGTGGTCCGCCACACAGACAGCAAACAGGAAAGCTTTATTTGGTGGATCTTGCCGGTTCAGAGGACAATCGGCGCACAGGAAACCAGGGCATTCGTCTGAAAGAGAGCGGAGCCATCAACTTGTCTCTGTTCACGCTCAGTAAGGTGGTGGACGCTCTGAACACAGGGGCTGGGGGCCGCGTGCCCTACAGAGACAGTAAACTCACCCGCCTGCTGCAGGACTCTTTGGGTGGATCCGCACATTCTGTCATGATCACAAACATCGCACCCGAGTACAAATACTACTTTGACACCTTTTCTGCACTTAATTTCGCCGCAAAGTCTAAGCAGATTGTCAATCGGCCTTTTGTCAGAGAAACTGTTTTGGCCCCTACGATTGCTCCTGGAAAGAGAACCAGAGAGGAACAGGAGGCTGGAGGTTCTGGTGAACCCCAGAACAAGAGATCCAAAGAAGGGAAGAAAGCTGAACATTCCCCATCACCGCCCTTACATCCACAGAGTTCACCAGATTCATCAGTTCTGGACCGACTCCTGGCTCTGGAGAAGATGATGATGGGCTCAGCTGAGAGGGAGAGACTCAACCTGCTCAAAACTGTTGCACAGTCCCGAAAAGAAATCCAGATGTTGAAGGAGAAACAGAAGGAGCTGGAGGACAAAGCCAACATGTTTAATAAGCAGAAAGAAACCACTGAGAAAGAGTCCAAAGATGCTCTTCTTTTCAAGACCGATCTGCCGCCCCTACACAGAAAACAGTCGACAGCCGCCAAACCACGCAAACAGCAGGCCGTTGTTACTCCATTACAGGTGTCTCAGGTGCAGCCCTTACAGCAGTGTGCAGTGGTCTGCAAACCCTCACAGACCTTGGTTAAGAAGAAACGTGTCCAAACGGAGGTGTGTGATGGAAAGGAAAACATAGGTGTGGATCTTCATCCTGTTGAAGATGTCAACTGGGAGTCCCGTCTGGATCCAGCATTACTGGAACAGTCCAGGAAGAAGATCCTGCAGACGCTCAACTCGGGCTCTCTGAAGGAGCTCAAGAGCCTGCAGCAGATCGGAGACAAGAAGGCCAAACTCATCATGGGATGGAGAGAGATTAATGGAGACTTCACACAGgtGGAAGACCTGAAGAAAATCGAAGGTGTTACAGTTAAACGATTCTCTTCTTTCATAAAGgCCAATATTCTCAGCAGTATGGGAAAGTGAAGCAATTTGAGCTGCTGTGACTGAAGAGGAGAGCCTGCATACTTGTTTTTAcatgtgttttatggatataatGTGTacagtttttaaacttttttttttctttgtgtataCTTGACTGCTGTTtttcttgttttcatttttcagtgaatTTCCTGCATACCTAGGccaattttttcttttatttaactttttaatctGTAAATGAACCTGTTTCATTTCATAAAGGCACTAAATAAATGCCATCATCACATA

Function

symbol description
kif22 Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Acts upstream of or within several processes, including central nervous system development; somitogenesis; and thigmotaxis. Predicted to be located in cytoplasm; cytoskeleton; and nucleus. Predicted to be part of kinesin complex. Predicted to be active in microtubule. Is expressed in brain. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia with joint laxity type 2. Orthologous to human KIF22 (kinesin family member 22).

GO:

id name namespace
GO:0001756 somitogenesis biological_process
GO:0007018 microtubule-based movement biological_process
GO:0048592 eye morphogenesis biological_process
GO:0021952 central nervous system projection neuron axonogenesis biological_process
GO:0007409 axonogenesis biological_process
GO:0007420 brain development biological_process
GO:0001966 thigmotaxis biological_process
GO:0005856 cytoskeleton cellular_component
GO:0005871 kinesin complex cellular_component
GO:0005874 microtubule cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0003777 microtubule motor activity molecular_function
GO:0008017 microtubule binding molecular_function
GO:0016887 ATPase activity molecular_function

KEGG:

id description
ko04914 Progesterone-mediated oocyte maturation
ko04812 Cytoskeleton proteins

ZFIN:

id description
ZDB-GENE-080204-34 Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Acts upstream of or within several processes, including central nervous system development; somitogenesis; and thigmotaxis. Predicted to be located in cytoplasm; cytoskeleton; and nucleus. Predicted to be part of kinesin complex. Predicted to be active in microtubule. Is expressed in brain. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia with joint laxity type 2. Orthologous to human KIF22 (kinesin family member 22).

Ensembl:

ensembl_id ENSDARG00000102624

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00008970 False 745 mRNA 0.50 5 5048044 5059743
TCONS_00008971 True 2287 mRNA 0.48 13 5048074 5071836

Neighbor

gene id symbol gene type direction distance location
XLOC_004490 arhgap27 coding upstream 3113 4971515 ~ 5044931 (+)
XLOC_004489 plekhm1 coding upstream 84891 4920451 ~ 4963153 (+)
XLOC_004488 cd79b coding upstream 141120 4900981 ~ 4906924 (+)
XLOC_004487 scn4aa coding upstream 154552 4869248 ~ 4893492 (+)
XLOC_004486 ghrhr2 coding upstream 193489 4845448 ~ 4854555 (+)
XLOC_004496 prrt2 coding downstream 9923 5081759 ~ 5095774 (+)
XLOC_004497 AL929469.3 coding downstream 17979 5089815 ~ 5089930 (+)
XLOC_004498 cep55l coding downstream 30834 5102670 ~ 5113389 (+)
XLOC_004499 pde6c coding downstream 57409 5129245 ~ 5154099 (+)
XLOC_004500 lgi1b coding downstream 117940 5189776 ~ 5204629 (+)
XLOC_004485 NA non-coding upstream 212730 4834849 ~ 4835314 (+)
XLOC_004484 NA non-coding upstream 296192 4748571 ~ 4751852 (+)
XLOC_004483 NA non-coding upstream 313056 4729017 ~ 4734988 (+)
XLOC_004480 CABZ01030103.1 non-coding upstream 550565 4497364 ~ 4497479 (+)
XLOC_004479 NA non-coding upstream 574896 4428123 ~ 4473148 (+)
XLOC_004512 NA non-coding downstream 1072869 6144705 ~ 6152579 (+)
XLOC_004513 NA non-coding downstream 1077171 6149007 ~ 6153121 (+)
XLOC_004514 NA non-coding downstream 1085127 6156963 ~ 6171928 (+)
XLOC_004515 NA non-coding downstream 1123334 6195170 ~ 6451609 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000047_03163127_03175326 KIF22 coding CI01000047 null 3162866 ~ 3175326 (-)