XLOC_004505 (dlx3b)


Basic Information

Item Value
gene id XLOC_004505
gene name dlx3b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 5708400 ~ 5711920 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00008989
CTCTGCCATTACCTTCAGTGCTTCAACAGAGGGAGTGTGAGAAAGCAGTTCATCGAGGATTTTGTGTTACAGGCATCGTCCCAAACCCAACGTCTGCATGACTTGCTTCGGTCTGCCTTGGAAATAAAGTGGACGATCGTTGTTTTTTCCTTCCTTATTAAGGATGAGTGGACCGACATATGACAGGAAGATACCCGGTATTTCGACCGATCTTTCAGGCTCTATGAGTTGCCATCCGACTTCTAAGGACTCTCCGACTCTCCCAGAGTCATCGGCTACAGACATGGGTTATTACAGCAGCCATCACGAATACTACCAGAGCCCTCCATATCCTCAACAGATGAACTCATATCATCAGTTTAATCTGTCAGGGATGGGGGCAACACCCGGAGCGTATCCCACCAAGACAGAGTATCCTTACAATACTTATAGACAATACGGACATTACAACAGAGACCTGCAGACGCCACCACAAAGTGCAGTCAAAGAGGAACCAGAGACTGAAGTGCGGATGGTAAACGGAAAACCCAAGAAAATTCGCAAGCCGCGCACCATTTACTCGAGTTACCAGCTCGCCGCGCTCCAGCGCCGCTTCCAGAAAGCGCAGTATCTGGCGCTGCCGGAGAGAGCTGAACTCGCCGCACAGCTGGGGCTCACACAGACACAGGTGAAAATCTGGTTCCAGAACCGGAGATCCAAGTTCAAGAAGCTTTACAAGAACGGCGAGGTTCCGCTAGAGCACAGCCCGAACGCCAGCGACTCCATGGCCTGCAACTCGCCTCCATCCCCGGCTGTTTGGGACAATAACGCGCACTCTAGCCAGGTCAACCGGGGGCAGATCCCCCAGCCACCCCTCAGTTCCACACCCCCCTACATGGAAGATTACAGCAATCACTGGTACCAGCAGGGATCACATTTACAGCATCCAGTGCACCACCCGGGACCACCGCAGAGCGTGGGGGCCGTGTATTAACAGACACTGATGGAAGAGTTTAATATAAGCGCAAAAAGACTTTTGGAAAAACTCCGCAGAAATAAGCTGACAGATACTCCGCGAGTATCTAGAGTGGAACAGCAAACTTCTGGACTGTTTGAACGCATATCTGTTGATATGAATGCtttgtgttaaaataataataatagtataataataaataattgtttcaATGTGTCCCGGCTACTCAGACCTATTTCACATGCACATAGGTGTAGGTTAAACGATGTAAAGGAAGTTTAGAGTggttttaaattattatgttgtATGACTTCCTTTATCTTCATGTTTTGCTCATTAATAGgtgaatattaaaaatgttttaaagaatgattgAACCCCAAATTGTGTTGTTATCAGCCACGTACGCCACCCACAATGTGGGCTGGAGTGGCGCGCGCTTCACAGACTCAGGACATAAGTTATAGACTGTACAAAATGTTGAAAGCTGTACATAAGTGTTTAAATAAAGCAGAACCACTAAATTCGTGTTACTTCAACAGATAGAGACTGCACGGTGGTGCTCGAACCATTTTATATTCCTGTAAGTAGTTTTATTGTTATTCTGTCAAACCGAATAAATGCAAAATGAAAATA

Function

symbol description
dlx3b Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including sensory organ development; skeletal system development; and trigeminal nerve development. Predicted to be located in nucleus. Is expressed in several structures, including ectoderm; neural plate; neurogenic field; pharyngeal arch; and presumptive structure. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 4 and trichodontoosseous syndrome. Orthologous to human DLX3 (distal-less homeobox 3).

GO:

id name namespace
GO:0021559 trigeminal nerve development biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0035270 endocrine system development biological_process
GO:0043010 camera-type eye development biological_process
GO:0060119 inner ear receptor cell development biological_process
GO:0030154 cell differentiation biological_process
GO:0071599 otic vesicle development biological_process
GO:0071600 otic vesicle morphogenesis biological_process
GO:0043049 otic placode formation biological_process
GO:0070306 lens fiber cell differentiation biological_process
GO:0007275 multicellular organism development biological_process
GO:0051216 cartilage development biological_process
GO:0048840 otolith development biological_process
GO:0071698 olfactory placode development biological_process
GO:0030855 epithelial cell differentiation biological_process
GO:0048666 neuron development biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0030910 olfactory placode formation biological_process
GO:0042667 auditory receptor cell fate specification biological_process
GO:0030916 otic vesicle formation biological_process
GO:0009790 embryo development biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-980526-280 Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including sensory organ development; skeletal system development; and trigeminal nerve development. Predicted to be located in nucleus. Is expressed in several structures, including ectoderm; neural plate; neurogenic field; pharyngeal arch; and presumptive structure. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 4 and trichodontoosseous syndrome. Orthologous to human DLX3 (distal-less homeobox 3).

Ensembl:

ensembl_id ENSDARG00000014626

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00008989 True 1591 mRNA 0.46 3 5708400 5711920

Neighbor

gene id symbol gene type direction distance location
XLOC_004504 ace coding upstream 126340 5530247 ~ 5582060 (+)
XLOC_004503 drd6b coding upstream 248197 5458462 ~ 5460203 (+)
XLOC_004502 plce1 coding upstream 309822 5251647 ~ 5398578 (+)
XLOC_004501 SLC35G1 coding upstream 483623 5209822 ~ 5224777 (+)
XLOC_004500 lgi1b coding upstream 503771 5189776 ~ 5204629 (+)
XLOC_004506 LO017821.1 coding downstream 63933 5775853 ~ 5810279 (+)
XLOC_004507 si:ch211-131k2.2 coding downstream 265857 5977777 ~ 5981577 (+)
XLOC_004508 si:ch211-131k2.3 coding downstream 290795 6002715 ~ 6006865 (+)
XLOC_004509 g6pca.2 coding downstream 329655 6041575 ~ 6048286 (+)
XLOC_004510 sgms1 coding downstream 353741 6065661 ~ 6114296 (+)
XLOC_004497 AL929469.3 non-coding upstream 618470 5089815 ~ 5089930 (+)
XLOC_004495 AL929469.1 non-coding upstream 646703 5061567 ~ 5061697 (+)
XLOC_004494 AL929469.2 non-coding upstream 651044 5057221 ~ 5057356 (+)
XLOC_004493 AL929469.4 non-coding upstream 655822 5052443 ~ 5052578 (+)
XLOC_004492 AL929469.5 non-coding upstream 656703 5051562 ~ 5051697 (+)
XLOC_004512 NA non-coding downstream 432785 6144705 ~ 6152579 (+)
XLOC_004513 NA non-coding downstream 437087 6149007 ~ 6153121 (+)
XLOC_004514 NA non-coding downstream 445043 6156963 ~ 6171928 (+)
XLOC_004515 NA non-coding downstream 483250 6195170 ~ 6451609 (+)
XLOC_004517 CU184911.1 non-coding downstream 996209 6708129 ~ 6708243 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000047_02747442_02755248 DLX3B coding CI01000047 null 2746901 ~ 2755248 (-)
bowfin (Amia calva) AMCG00016736 dlx3,dlx3b coding CM030122.1 CM030122.1 28949450 ~ 28953796 (-)