XLOC_005703 (bmp5)


Basic Information

Item Value
gene id XLOC_005703
gene name bmp5
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 1872767 ~ 1906732 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00011312
GTGCGCTTCTGCTCACAGGTGAAGAGCGCGCGCATAGTCACATACATACCGCGTTAATCGAAGCAATCTGAATGATAGCAGAGAGGATGTAGTGAAGAAAGAAGTCCAAACAGAGTCTAAAGAAGGATTTAATACTTTTGTGGAGGAGAAAGTTGGTGCGCCATGGAGAGCAGCAGCATCATCAGCTGAAAGCATCATCATCCTGGTCAAGATGAGAACATTTGGACTTCTGTGGAGCTGTTTAGGCTTTCTTCACGGCGTTCAGTGCGGTTTGGGAGACAACCATGTGCACTCGAGCTTTATTTACAGGCGCTTGCGGAACCACGAGCGCCGCGAGATCCAGAGAGAGATCCTCTCCATCCTGGGCTTGCCTCACCGACCCAGGCCGTTCTCCCCGGGCAAGCAGGCGTCGTCCGCGCCGCTCTTCATGCTGGATCTCTACAACGCGATGACGACGGAAGAGGAGAACGAGATACTGGGGAAATCGCTCGCGGGGAAAGTGCGTAAAAGCGCGCCCGGAGCTCCGCACGGATATTCGCGCGCGCCACCGCGTGTTCCGCAGCCGCAACACTCCCGCGCCGCGCCGCTCAGCAGCCAGAGCCCGCCGCTGGCGAACGCGCACGACACAAACTTTCTTAATGATGCGGACATGGTCATGAGTTTTGTCAATCTAGTGGAGCGGGATAAGGATTTCTCCCACCACAGGCGACACTACAGGGAGTTTCGCTTTGACCTGACTCAGATCCCAGAAGGTGAAGCGGTGACCGCTGCTGAGTTCAGGATTTATAAGGATCAAAGTCACATCAGATATGAGAACATCACGCTGAAGGTCACCATATATCAGGTCATCAAAGAATATCCAAACAGGGATCCTGACACGTTTCTGTTGGACTGGAAGAAGATCCGCGCTACTGATGGAGGATGGCTGGTGTTTGACATCACGGCCACCAGCAATCACTGGGTCCTGAACCCGCAGCAGAACATGGGCCTTCAGCTGTGTGTGGAGACCACCGATGGTAGAAGCATCAACATGAAATCTGCTGGCATCATCGGCAGGAACGGACCTCAGTCCAAACAGCCGTTCCTGGTGGCTTTTTTCAAAGCCAGCGAGGTTTTGCTTCGTTCTGTGAGAGCCACGGGAAGCAAGAAGAAGAGCCACAAcagaaacaaaagcaaaacacaagCGAAATCAACACCAGCTCTCAAAAGCGGAGATCAGAACACCAGTGAACAGAGGCAAGCCTGCAAGAAACACGAACTCTACGTCAGCTTCCGGGATCTGGGATGGCAGGACTGGATTATTGCTCCAGAAGGCTACGCTGCCTTTTACTGTGATGGAGAATGTTCATTTCCACTGAACGCACATATGAATGCCACGAATCATGCCATTGTGCAGACCTTGGTCCATCTGATGTTTCCGGATAACGTGCCAAAGCCTTGCTGTGCTCCGACCAAACTGAACGCCATCTCTGTGCTGTATTTCGACGACAGCTCCAATGTTATTCTGAAGAAGTACAGGAATATGGTGGTGCGGTCCTGTGGGTGTCACTGAGAGAAGACGGTGTCGTATTGCTGGATTTAAGAACATATCAAGAGAAATAGTTTTGAGATTTGATGTACagtattatgtatatattagcTCATAATTCCTCTTATTTATTTGGCTTTGTTTTGTTATAAGATGTAGTTCAGTTATAACCTGGTTACCACTCTCACCACACATTCATGGCTCATTGCTGTTTCTCTCAGAGTATTTCAATGAGGTGAAAAAGTTAGAGAGCGTCTTATAAACGTCCTTTGTTTCAAAGACATCATCAATTCATCAGCGACCactccaaaaaacaaaactgctgcTATTGTACGACAGAAATGTAAGCAAACAAAGAACAGCCATATTGAAATTTGCAAACCAAAACAGTTTTTCTTTAATTTAGTCATTGTAGTATTGTTTTAAAAGCACTGAGAATGTCTTAGGACTCTGTAGTACATATTTCCTCAAGCAGCCCAAAGTATTGCAGCCCGCAGTTACTGATGATGTTAGTTTGCTGTAGATGTCAGTGGGTGGATATGCAAAATCAAATATTCTTTCtccttatatacacacacacacttgtatttgTACTCTGAGTAATATATTTTTGGGAAGATATTGCATTTATTGTTTTAGAACCATGTTTGTATGTCATTAAATCTATTTTCCAAT

Function

symbol description
bmp5 Predicted to enable BMP receptor binding activity and cytokine activity. Acts upstream of or within neural crest cell development; positive regulation of ERK1 and ERK2 cascade; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including neural crest; optic vesicle; periderm; pharyngeal arch; and sensory system. Orthologous to human BMP5 (bone morphogenetic protein 5).

GO:

id name namespace
GO:0060395 SMAD protein signal transduction biological_process
GO:0030509 BMP signaling pathway biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:0014032 neural crest cell development biological_process
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005125 cytokine activity molecular_function
GO:0070700 BMP receptor binding molecular_function
GO:0008083 growth factor activity molecular_function

KEGG:

id description
ko04350 TGF-beta signaling pathway
ko04390 Hippo signaling pathway
ko04060 Cytokine-cytokine receptor interaction
ko04052 Cytokines and growth factors

ZFIN:

id description
ZDB-GENE-040426-1413 Predicted to enable BMP receptor binding activity and cytokine activity. Acts upstream of or within neural crest cell development; positive regulation of ERK1 and ERK2 cascade; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including neural crest; optic vesicle; periderm; pharyngeal arch; and sensory system. Orthologous to human BMP5 (bone morphogenetic protein 5).

Ensembl:

ensembl_id ENSDARG00000101701

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00011312 True 2203 mRNA 0.47 7 1872767 1906732

Neighbor

gene id symbol gene type direction distance location
XLOC_005702 col21a1 coding upstream 6056 1799003 ~ 1866711 (+)
XLOC_005700 zmp:0000000760 coding upstream 86622 1726953 ~ 1786145 (+)
XLOC_005701 CABZ01044297.1 coding upstream 107145 1765507 ~ 1765622 (+)
XLOC_005699 DST coding upstream 152837 1575276 ~ 1719930 (+)
XLOC_005698 CABZ01044281.1 coding upstream 319840 1542493 ~ 1552927 (+)
XLOC_005704 hmgcll1 coding downstream 21629 1928361 ~ 1981727 (+)
XLOC_005705 NA coding downstream 76579 1983311 ~ 2033043 (+)
XLOC_005706 NA coding downstream 243038 2149770 ~ 2153016 (+)
XLOC_005707 klhl31 coding downstream 432029 2338761 ~ 2350762 (+)
XLOC_005708 CR376766.2 coding downstream 445557 2352289 ~ 2352995 (+)
XLOC_005687 NA non-coding upstream 886504 973009 ~ 986263 (+)
XLOC_005685 NA non-coding upstream 1010871 859057 ~ 861896 (+)
XLOC_005671 NA non-coding upstream 1168429 471548 ~ 704338 (+)
XLOC_005710 CR376766.1 non-coding downstream 479681 2386413 ~ 2386533 (+)
XLOC_005715 NA non-coding downstream 764700 2671432 ~ 2676336 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000005_05538096_05558622 BMP5 coding CI01000005 null 5537380 ~ 5558655 (+)