AMCG00012739 (ube2na,ube2nb,ube2n,LOC105897570,LOC107658971,LOC107707098,LOC107555890)


Basic Information

Item Value
gene id AMCG00012739
gene name ube2na,ube2nb,ube2n,LOC105897570,LOC107658971,LOC107707098,LOC107555890
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030125.1
NCBI id CM030125.1
chromosome length 49972098
location 6280300 ~ 6282779 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00012739
tttaaatgttctaactgcaggaaatgaaaaatacaccaACCAATACGCCAAAATGTCAACCTTTTGTCATGTAAGCTTTGCTGAAATAATTTGACTTTGTGCTAGCATGCTGTGAAGCAGCTGAATCGCCTGACGGCAGTGTTGTCTTGCCATTAGCACAAAGCTTTTCCTGTTGACAATGCATGCTTGTTATCATAAATGATTGCTCCTTGTAAATACATATTGGTAAAATCAGCTTTTTAATGCTTCTCACGTGCCAGTGTTTTGAATTACGGATTGATGTTCATTGAGGGGCTGTTAAGATCAGAATTTTAAGATGGCATTGCAAAAGGAATTCCAAACAACATGATGTATTCTTTTCTGAAGTCAAATGAAACGCccagtatgtttttattcagtatAGTGCGATGTTGCCCCAGATTTTTCCCGCACATGAAGTTAAAGGGAGACaagttattttataaaaatgtatttaagaacaTTATGGTAATgaagaggaaggagaaaaaGAGAATCAGTCGACCTACAGGAGAGAGAAACTAAAACCTGCTCTAGGAAAACCGTtctaggagaaaataaatcaagtggTTTTCAGGAACGATGATGAAGCTCAGCCTGGTGTGTGACAGCGCCCCATCTTCTCTCTTTCGCTCTTTTCTCTCCAGGAGACACAACGCTTACTGGCAGAGCCGGTTCCTGGGATAAAGGCCGAGCCGGACGAAGGCAATGCTCGCTATTTCCATGTGGTTATCGCTGGTCCACAGGATTCCCCCTTTGAGGGCGGGACTTTTAAACTTGAACTATTCCTTCCAGAAGAATATCCAATGGCAGCTCCTAAAGTTCGTTTCATGACCAAAATATATCACCCTAATGTAGACAAGCTGGGAAGAATATGTCTAGATATTTTGAAAGATAAGTGGTCTCCAGCCTTGCAGATTCGCACAGTCCTGCTATCAATCCAGGCGTTATTAAGTGCTCCTAACCCTGATGATCCACTAGCAAATGATGTTGCAGAGCAGTGGAAAACCAACGAAGCTCAAGCCATAGAAACAGCCCGGACATGGACTAGGCTTTATGCCGGCAACAATATTGAAGTTTAATCAGAAGTCAAGTGTGAGTGAACAAAACTCCTCCTGTTCTGCCAAGATCTCTTCCTTCTTCGTTTGCATTTAAAGGACACAGtcttagaaaaagaaaaataatacagaattaaaaataatgtaaaaaaagcaaaaaacaacaacaaaagcagaaacCAGACAACTACAGTCCATTGgtgatttaaatgcacattaGCAAATATTTGTCTTGTCCTGATTCACTGTTATAATGCATGAGCAGAGGCTAGAAATATACCACGTggcttttttttacatttggttCTAAAGCAGTGGCCCGCCTCtgcttttatttgcatataACTGGCATTGTTCGACTGTACCTGGAAGTGAATGTTCGGGTTTCGCTGCAGGAAcggtgtatttttgtgtttgtttgtttcgttctgtttttttggctttggttttccttttttttctccttcctgtGATGATGCTAATGGTTTATTAAAGCAGCTGATTAGAACAACATAGCTCATGCCCTCTAGCCAGGTCTGGTTCACCCTTTAGATGCTTTAGAGAAAAAAGCTTGGCTTTTCAAACATccaacttaaattaaataagaataataaagcCACCTCCACCGCCATCACTAATAACATTGTGACTGCTATCAAGTGTATACCCTAATATAGGCTTGTGACTTTTTGTATGGCTtgtctggagaaaaaaataatctgtaaatcttatgttttagtaaaatattttttttg

Function

symbol description
ube2na Predicted to enable ubiquitin conjugating enzyme activity. Acts upstream of or within DNA damage response, detection of DNA damage and protein polyubiquitination. Predicted to be active in nucleus. Orthologous to several human genes including UBE2N (ubiquitin conjugating enzyme E2 N).
ube2nb Predicted to enable ubiquitin binding activity and ubiquitin conjugating enzyme activity. Acts upstream of or within DNA damage response, detection of DNA damage. Predicted to be part of UBC13-MMS2 complex. Predicted to be active in nucleus. Orthologous to several human genes including UBE2N (ubiquitin conjugating enzyme E2 N).
ube2n Enables ubiquitin binding activity; ubiquitin protein ligase binding activity; and ubiquitin-protein transferase activity. Involved in several processes, including DNA repair; protein ubiquitination; and regulation of protein modification process. Located in cytoplasm; fibrillar center; and nucleoplasm. Part of UBC13-MMS2 complex; UBC13-UEV1A complex; and ubiquitin ligase complex.

NR:

description
ubiquitin-conjugating enzyme E2 N

GO:

id name namespace
GO:0006301 postreplication repair biological_process
GO:0045739 positive regulation of DNA repair biological_process
GO:0051443 positive regulation of ubiquitin-protein transferase activity biological_process
GO:0033182 regulation of histone ubiquitination biological_process
GO:0042769 DNA damage response, detection of DNA damage biological_process
GO:0031058 positive regulation of histone modification biological_process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling biological_process
GO:0000209 protein polyubiquitination biological_process
GO:0000724 double-strand break repair via homologous recombination biological_process
GO:0000729 DNA double-strand break processing biological_process
GO:0051092 positive regulation of NF-kappaB transcription factor activity biological_process
GO:0050852 T cell receptor signaling pathway biological_process
GO:0031372 UBC13-MMS2 complex cellular_component
GO:0005634 nucleus cellular_component
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0043130 ubiquitin binding molecular_function

KEGG:

id description
K10580 UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00012739 True 1831 mRNA 0.39 3 6280300 6282779

Neighbor

gene id symbol gene type direction distance location
AMCG00012738 NA coding upstream 10857 6265742 ~ 6269443 (+)
AMCG00012740 LOC105905702 coding upstream 15506 6243907 ~ 6264794 (+)
AMCG00012741 btbd11,btbd11a,LOC106573291,LOC100703440 coding upstream 49010 6193260 ~ 6231290 (+)
AMCG00012737 btbd11a,btbd11,LOC107757250,LOC107694300,LOC107592010 coding upstream 178690 6100581 ~ 6101610 (+)
AMCG00012729 NA coding upstream 240710 6032753 ~ 6039590 (+)
AMCG00012750 NA coding downstream 101026 6383805 ~ 6412746 (+)
AMCG00012749 asun coding downstream 155264 6438043 ~ 6453810 (+)
AMCG00012747 NA coding downstream 262453 6545232 ~ 6579959 (+)
AMCG00012746 NA coding downstream 343215 6625994 ~ 6627816 (+)
AMCG00012753 NA coding downstream 360566 6643345 ~ 6759575 (+)
G39382 NA non-coding upstream 357277 5922614 ~ 5923023 (+)
G39321 LOC100846954 non-coding upstream 632193 5647774 ~ 5648107 (+)
G39279 NA non-coding upstream 843138 5436833 ~ 5437162 (+)
G39193 NA non-coding upstream 1206174 5037547 ~ 5074126 (+)
G39186 NA non-coding upstream 1324433 4949240 ~ 4955867 (+)
G39445 NA non-coding downstream 2155 6284934 ~ 6287936 (+)
G39490 LOC103376870 non-coding downstream 229869 6512648 ~ 6536393 (+)
G39538 NA non-coding downstream 479186 6761965 ~ 6762278 (+)
G39560 NA non-coding downstream 615218 6897997 ~ 6898230 (+)
G39586 NA non-coding downstream 930966 7213745 ~ 7218459 (+)
AMCG00012734 NA other upstream 223468 6053148 ~ 6056832 (+)
AMCG00012718 NA other upstream 456785 5807846 ~ 5823515 (+)
G39297 NA other upstream 727533 5552417 ~ 5552767 (+)
G38954 NA other upstream 1906726 4370313 ~ 4373574 (+)
AMCG00012681 NA other upstream 2028706 4183875 ~ 4251594 (+)
AMCG00012748 itpr2,LOC100196824 other downstream 193470 6476249 ~ 6517983 (+)
AMCG00012763 NA other downstream 1061671 7344450 ~ 7381559 (+)
G39670 kcnj8,LOC108279966,LOC107725582,LOC107655555,LOC107587158,LOC107729834 other downstream 1442709 7725488 ~ 7727828 (+)
G39709 LOC101154678 other downstream 1552567 7835346 ~ 7836214 (+)
AMCG00012797 NA other downstream 2053119 8335898 ~ 8345855 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_012691 ube2na coding NC_007129.7 CM002902.2 15778110 ~ 15793163 (+)
grasscarp (Ctenopharyngodon idella) CI01000013_06629494_06632725 UBE2NA, UBE2NB, MCG1038069, UBE2N coding CI01000013 null 6629494 ~ 6632725 (-)