nuf2 (nuf2)


Basic Information

Item Value
gene id nuf2
gene name nuf2
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035918.1
NCBI id CM008321.1
chromosome length 32506130
location 12926056 ~ 12940460 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007229617.3
CGTGCGCTCTGCTGCGCTGGGTGGTTGGTGGAAGTGACGTCAGGGGCGGGTAAAGTTTAAATCGGCTGCTGGAGGCGAGAGGCAGctgcaatggaaaacacatttCCCGTGTACAAAGTCGACGCTATTGTGCAGTTTTTCCGCACAGATGTTTTAACGGGCCAAGAAGCGAAGCACTTCGCTAAAAGTGATCTCACTCCAAACCCCAAGGCAGATGTTATACAAAGAGTCTACATGAGGGTGCTACAGCTTCTGTATGGTTTCCGTCCTGAATGCCATTACCTGGCACCTCTATCTGAAAACATCCAGTGTATGTCTTTGTATGAATATGCCACTCCAATTATGAGTGTCTACTTGTCCATGTGCCAGTTTTTACCGATGTGTCATGTGTACGACTTTTCACTGAATGACTTGCTCAATCCAAagccAAAACGCACAATCACCATCCTGAGTGGCATCCAGAACTTTCTACACTTTAGGAAACAGAGGCTGGAAATAATAGCAGGGCATCAGCAAGCTTTTCGGGCAGACATGGATAAACTTCAGGCTTGCAACAAAGGAATTAAGGATGCTGAGAAGATGATCGAGAAGCTGATGATTATCCCACCAGAGCAGCAGGCAGAAGCTAAGGAGTTGGCAGCTGCCCTCAAAGAAGTAAACAGTGCCACCACACAGGAGTCCCAAGAAGTGAGTGCCCTGAATGAACAGGTGGCCGAGTGCAAAACTGAAATTGCAGAAAAGTCACAGAAACTGAGCCAGAGGAAGTTAGAAGTGGCCACCCAGAAGGATGAGATCGCCAAGCTCAAGTCACAGATAGTAGAATCCCCCGAAGAAGTCAAAAATGAAATGGAGAAGATGAAGGAAAACATCAAGAACATAAAGAATTCAAAGgagCTGGCTGATGAGATGCTGGTAGACCTGCAGATCAAGGTGCAGTGTGCCAGCCAGGGGGAAGCAGACATCCAGGTCATACTGAAACAGCTGCATGACCTGCAGGCTAGCATGTGCAAGACCAACCAGCAGAAGGAGGAGGTCCAGAGCTTGGTGGCCCTCTCTGAGAACCTGCAGAAGGAGCTGAAGGCCCTTAGCAATGAAGAGGGTCAGATGAAGAGAGCGCTGGCCATGAAACTAGACAAGGAGTCCAAGCAGCAGATACGCCGCCAGAAGAAGAAGGAGCTAAAGGACCAGCATGTCCAAAGTATTATTGGgcaatatgacaaaatccATGAAAAACGGGAGGAAATTGTGGAACGGATAAAGCACATCAACTCAGAAACACGGCAGTTCAAGGAGAAGATGCAGAAGCTGCGAGACACCTGCAACCAGAACAGTGAAAAGGCTCAGGCTATCTATGATCGTCTTCTGACCACACTGGAGCAGTTCCACAAGCGCATTGAGAATATTGTGGTAGAGGCCACTGCAGACATGACgaaaatgaaaactgtgttttaaactaATTTTTGTAGACACAGTTTTGAGGTATGCTTCCTTTTTGTCATTGTAGTCCTTTTTTGAATATTTccatttatgtgtgtgtgtgtgtatattgttcTACTGTAAATAATTGTGCTCCTCTGTTTTGTTGAATAAAATTCCATATCTTTGTTCGATA
>XM_015605043.2
GTAACTAATaatctgtgtttctgtaaagaaaaactgaattttATTCCATTTACAGCGCTTAAATTGCCTGTAGACATGGCTGAGGTGAATTCTGAAAAAGATGctgcaatggaaaacacatttCCCGTGTACAAAGTCGACGCTATTGTGCAGTTTTTCCGCACAGATGTTTTAACGGGCCAAGAAGCGAAGCACTTCGCTAAAAGTGATCTCACTCCAAACCCCAAGGCAGATGTTATACAAAGAGTCTACATGAGGGTGCTACAGCTTCTGTATGGTTTCCGTCCTGAATGCCATTACCTGGCACCTCTATCTGAAAACATCCAGTGTATGTCTTTGTATGAATATGCCACTCCAATTATGAGTGTCTACTTGTCCATGTGCCAGTTTTTACCGATGTGTCATGTGTACGACTTTTCACTGAATGACTTGCTCAATCCAAagccAAAACGCACAATCACCATCCTGAGTGGCATCCAGAACTTTCTACACTTTAGGAAACAGAGGCTGGAAATAATAGCAGGGCATCAGCAAGCTTTTCGGGCAGACATGGATAAACTTCAGGCTTGCAACAAAGGAATTAAGGATGCTGAGAAGATGATCGAGAAGCTGATGATTATCCCACCAGAGCAGCAGGCAGAAGCTAAGGAGTTGGCAGCTGCCCTCAAAGAAGTAAACAGTGCCACCACACAGGAGTCCCAAGAAGTGAGTGCCCTGAATGAACAGGTGGCCGAGTGCAAAACTGAAATTGCAGAAAAGTCACAGAAACTGAGCCAGAGGAAGTTAGAAGTGGCCACCCAGAAGGATGAGATCGCCAAGCTCAAGTCACAGATAGTAGAATCCCCCGAAGAAGTCAAAAATGAAATGGAGAAGATGAAGGAAAACATCAAGAACATAAAGAATTCAAAGgagCTGGCTGATGAGATGCTGGTAGACCTGCAGATCAAGGTGCAGTGTGCCAGCCAGGGGGAAGCAGACATCCAGGTCATACTGAAACAGCTGCATGACCTGCAGGCTAGCATGTGCAAGACCAACCAGCAGAAGGAGGAGGTCCAGAGCTTGGTGGCCCTCTCTGAGAACCTGCAGAAGGAGCTGAAGGCCCTTAGCAATGAAGAGGGTCAGATGAAGAGAGCGCTGGCCATGAAACTAGACAAGGAGTCCAAGCAGCAGATACGCCGCCAGAAGAAGAAGGAGCTAAAGGACCAGCATGTCCAAAGTATTATTGGgcaatatgacaaaatccATGAAAAACGGGAGGAAATTGTGGAACGGATAAAGCACATCAACTCAGAAACACGGCAGTTCAAGGAGAAGATGCAGAAGCTGCGAGACACCTGCAACCAGAACAGTGAAAAGGCTCAGGCTATCTATGATCGTCTTCTGACCACACTGGAGCAGTTCCACAAGCGCATTGAGAATATTGTGGTAGAGGCCACTGCAGACATGACgaaaatgaaaactgtgttttaaactaATTTTTGTAGACACAGTTTTGAGGTATGCTTCCTTTTTGTCATTGTAGTCCTTTTTTGAATATTTccatttatgtgtgtgtgtgtgtatattgttcTACTGTAAATAATTGTGCTCCTCTGTTTTGTTGAATAAAATTCCATATCTTTGTTCGATA
>XM_022682398.1
GGACGATGGCAATAGCCAATCGCAACGACAGTGTGGCGGGGCCTATACAAGTAcagctgcaatggaaaacacatttCCCGTGTACAAAGTCGACGCTATTGTGCAGTTTTTCCGCACAGATGTTTTAACGGGCCAAGAAGCGAAGCACTTCGCTAAAAGTGATCTCACTCCAAACCCCAAGGCAGATGTTATACAAAGAGTCTACATGAGGGTGCTACAGCTTCTGTATGGTTTCCGTCCTGAATGCCATTACCTGGCACCTCTATCTGAAAACATCCAGTGTATGTCTTTGTATGAATATGCCACTCCAATTATGAGTGTCTACTTGTCCATGTGCCAGTTTTTACCGATGTGTCATGTGTACGACTTTTCACTGAATGACTTGCTCAATCCAAagccAAAACGCACAATCACCATCCTGAGTGGCATCCAGAACTTTCTACACTTTAGGAAACAGAGGCTGGAAATAATAGCAGGGCATCAGCAAGCTTTTCGGGCAGACATGGATAAACTTCAGGCTTGCAACAAAGGAATTAAGGATGCTGAGAAGATGATCGAGAAGCTGATGATTATCCCACCAGAGCAGCAGGCAGAAGCTAAGGAGTTGGCAGCTGCCCTCAAAGAAGTAAACAGTGCCACCACACAGGAGTCCCAAGAAGTGAGTGCCCTGAATGAACAGGTGGCCGAGTGCAAAACTGAAATTGCAGAAAAGTCACAGAAACTGAGCCAGAGGAAGTTAGAAGTGGCCACCCAGAAGGATGAGATCGCCAAGCTCAAGTCACAGATAGTAGAATCCCCCGAAGAAGTCAAAAATGAAATGGAGAAGATGAAGGAAAACATCAAGAACATAAAGAATTCAAAGgagCTGGCTGATGAGATGCTGGTAGACCTGCAGATCAAGGTGCAGTGTGCCAGCCAGGGGGAAGCAGACATCCAGGTCATACTGAAACAGCTGCATGACCTGCAGGCTAGCATGTGCAAGACCAACCAGCAGAAGGAGGAGGTCCAGAGCTTGGTGGCCCTCTCTGAGAACCTGCAGAAGGAGCTGAAGGCCCTTAGCAATGAAGAGGGTCAGATGAAGAGAGCGCTGGCCATGAAACTAGACAAGGAGTCCAAGCAGCAGATACGCCGCCAGAAGAAGAAGGAGCTAAAGGACCAGCATGTCCAAAGTATTATTGGgcaatatgacaaaatccATGAAAAACGGGAGGAAATTGTGGAACGGATAAAGCACATCAACTCAGAAACACGGCAGTTCAAGGAGAAGATGCAGAAGCTGCGAGACACCTGCAACCAGAACAGTGAAAAGGCTCAGGCTATCTATGATCGTCTTCTGACCACACTGGAGCAGTTCCACAAGCGCATTGAGAATATTGTGGTAGAGGCCACTGCAGACATGACgaaaatgaaaactgtgttttaaactaATTTTTGTAGACACAGTTTTGAGGTATGCTTCCTTTTTGTCATTGTAGTCCTTTTTTGAATATTTccatttatgtgtgtgtgtgtgtatattgttcTACTGTAAATAATTGTGCTCCTCTGTTTTGTTGAATAAAATTCCATATCTTTGTTCGATA

Function

symbol description
nuf2 Acts upstream of or within heart development. Predicted to be located in kinetochore and nucleus. Predicted to be part of Ndc80 complex. Is expressed in proliferative region. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and pancreatic cancer. Orthologous to human NUF2 (NUF2 component of NDC80 kinetochore complex).

NR:

description
kinetochore protein Nuf2

GO:

id name namespace
GO:0007507 heart development biological_process
GO:0000777 condensed chromosome kinetochore cellular_component
GO:0031262 Ndc80 complex cellular_component
GO:0005634 nucleus cellular_component

KEGG:

id description
K11548 NUF2, CDCA1; kinetochore protein Nuf2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007229617.3 False 1612 mRNA 0.46 14 12926056 12939867
XM_015605043.2 True 1630 mRNA 0.44 14 12926056 12939782
XM_022682398.1 False 1583 mRNA 0.46 14 12926056 12940460

Neighbor

gene id symbol gene type direction distance location
shisa5 NA coding downstream 3076 12905330 ~ 12922980 (-)
LOC103025083 LOC108431510,LOC107586924,LOC107756006,LOC107593103,LOC107704447,LOC105893506 coding downstream 41274 12880822 ~ 12884782 (-)
ippk ippk,LOC107755999,LOC107658385 coding downstream 71663 12820875 ~ 12854393 (-)
LOC111195440 NA coding downstream 140871 12770735 ~ 12785185 (-)
LOC103030591 LOC108435310,LOC108281021,LOC107715788,LOC107659540,LOC107575639 coding downstream 169873 12714488 ~ 12756183 (-)
LOC103034476 zgc:77375,LOC108431553,LOC108254961,LOC107700631,LOC107758152 coding upstream 12050 12952510 ~ 12972311 (-)
LOC103027102 isy1,LOC108431508,LOC108254962,LOC107700632 coding upstream 33480 12973940 ~ 12980817 (-)
LOC111195380 NA coding upstream 42961 12983421 ~ 12990268 (-)
LOC103027392 cnbp,cnbpb,LOC106583855,LOC107742030,LOC108431552,LOC106566283,LOC108254964,LOC107742027,LOC107675970 coding upstream 54019 12994479 ~ 12998610 (-)
mkrn2 mkrn2 coding upstream 93116 13033576 ~ 13047546 (-)
G189385 NA non-coding downstream 22896 12902937 ~ 12903160 (-)
G189381 NA non-coding downstream 29448 12894863 ~ 12896608 (-)
G189380 NA non-coding downstream 34787 12890834 ~ 12891269 (-)
G189376 NA non-coding downstream 45712 12879945 ~ 12880344 (-)
G189352 NA non-coding downstream 157345 12768010 ~ 12768711 (-)
G189402 NA non-coding upstream 89710 13030170 ~ 13032240 (-)
G189404 NA non-coding upstream 110099 13050559 ~ 13053733 (-)
G189417 timp4 non-coding upstream 249318 13189778 ~ 13194807 (-)
G189418 NA non-coding upstream 266580 13207040 ~ 13210220 (-)
G189419 NA non-coding upstream 270328 13210788 ~ 13211185 (-)
LOC111195455 NA other downstream 212024 12612611 ~ 12714032 (-)
G189335 psma5,LOC107685984 other downstream 306490 12614912 ~ 12619566 (-)
mapkapk3 mapkapk3,LOC102784126,LOC107384936,LOC101473327,LOC102305022,LOC102199310,LOC106525176 other downstream 530524 12298049 ~ 12395532 (-)
eogt eogt,LOC107729408 other downstream 747446 12160542 ~ 12178610 (-)
G189055 NA other downstream 881763 12043913 ~ 12044293 (-)
tsen2 NA other upstream 122339 13062799 ~ 13076742 (-)
LOC103024926 dynlrb1,LOC106565026 other upstream 2378183 15318643 ~ 15322175 (-)
LOC103026676 LOC108424672,LOC108254855,LOC107691347,LOC107749448,LOC107685659,LOC107551122,LOC106582641 other upstream 2468747 15409207 ~ 15466584 (-)
G190405 fbln2,LOC108424659,LOC107727849,LOC107691338 other upstream 3405241 16345701 ~ 16460928 (-)
ptpdc1 NA other upstream 3629163 16569623 ~ 16599317 (-)

Expression


Co-expression Network