XLOC_001221 (ugdh)


Basic Information

Item Value
gene id XLOC_001221
gene name ugdh
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 23283532 ~ 23294753 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001968
AGCTGCTGCTGAAACGCTGTTGTTCACACGTAGCGTTTCGCCGTCTTTGCCATCACGTCAAATTTAAAGCACCGATATTCATTTCGCCCTATAGATAATGCGAGTGttgctgaattgaatttaaactgtaaaaacgCGTTTTGGTAAAAAAGGCTTATTAGATTTGCTTACGCCATTGTCAGAATAAGATTTGTTTTGCGCTGGCTTAGTTAGCGAAGCTCTTAGTTTGAAGAGACTGCATGTACCCGGAAGTAGATGTGTACTCTCCCCTCTCTGAAGTGTTTACGTTGCTATCTCCTCCCGGTGGGGGTGTGTATGTGTATtagtgtgtctgtctgtatgtacTGCCAGAGTTCATGTATcaatagtttattcattcaaGAACAAGGCGCCTCAGACGAAGGAATCTTACCTGCATACAACGCTGAGTTTCATGAAGTATATCTGTAACTAAAGAGCTGCTCTGTAAGACACGATGTTTCAGATTAAAAAGATTTGCTGTATAGGCGCTGGGTATGTTGGTGGTCCAACTTGTAGTGTCATTGCCAGCATGTGTCCTGAGATCACGGTAACAGTGGTGGATGTTAATGAATCCCGGATCAAAGCCTGGAACTCTGATACACTACCCATttatgagcCGGGCCTGAATGAAGTGGTGTTGTCTTGTCGCGGGAAGAACCTCTTCTTCTCCACAGATATAGACTCTGCCATTAAAGAAGCTGATTTGGTCTTCATTTCAGTAAACACCCCAACTAAGACGTACGGTATGGGCAAAGGGCGCGCTGCTGATCTGAAGTTTATTGAGGCATGTGCCCGGCGGATTGTAGAGGTGTCAGACGGGTATAAAATCGTTACAGAGAAGAGCACAGTGCCAGTTCGTGCAGCTGAGAGCATACGCAGGATATTTGATGCCAATACCAAACCCAGCCTTAATCTacagGTTCTCTCTAACCCAGAGTTCCTTGCAGAGGGTACGGCAGTAAAGGACCTTAAAGAGCCAGACCGCGTCTTGATTGGTGGAGATGAGACTCCGGAGGGTCAAAGGGCTATCAGTGCTCTCTGTGCAGTTTATGAGCACTGGGTCCCTAAAACACGCATCATCACCACCAACACCTGGTcctctgaactttctaaactgGCAGCAAATGCGTTCCTGGCTCAGCGCATCAGCAGTATAAACTCCATCTCTGCGCTGTGTGAATCCACTGGTGCTGATGTGGAGGAGGTGGCCAGAGCCATTGGCATGGACCAGCGAATTGGCAGCAAGTTCCTCAAAGCCAGCGTCGGATTTGGAGGAAGTTGTTTTCAGAAGGATGTGCTGAATTTGGTTTACCTCTGTGAAGCACTGAATCTACCAGAGGTTGCTTCATACTGGCAGCAGGTGATTGACATGAATGAATATCAGAGAAAGAGATTCGCCTGTCGGATCATTGACTGCCTGTTTAACACGGTTACAGGGAAGAAAATCGCCTTGTTGGGTTTCTCCTTCAAGAAAGACACGGGAGACACCAGAGAGTCGTCCAGTATTTACATTTCAAAGTATTTGATGGACGAAGGAGCCAAGCTGCATATTTATGACCCTAAAGTACTGAAAGAGCAGATAATCCAGGACCTGTCTCAACCCGGCATCTCCGGAGACAATCCagaaagagTGTCTGATCTTGTAACAGTGACGGTTGACCCCTATGAGGCCTGTGAAAGTGCACATGCTCTGGTCATCTGTACAGAGTGGGATATGTTTAAGgacCTGGATTATGAGAAAATATATCACAAGATGTTGAAACCAGCGTTCATTTTTGATGGACGACGAGTCCTGGATCATCTGCATACCCAACTACAAAACGTTGGCTTTCAGatcgagaccatcGGTAAGAAGGTGATGACACGAATCCCCTTCACAACCTCTGGAGGAGTACCACGAATCACTGAACCACCAGTAAAGAAATCCAAAGCCTGAGGCACAGCTCATCGTCCACACCACACACACGCAGGCACTTTACGCTAATCAAAGTCTTTCTCTGAGAAAACCAAAGTAATGTGTGACCATTGCTGGAAATCAACAGACTCTTCTGTTAGTAAAAGTGCAcatgctctgtgtttgtgtgtgtgtgttgaactgTGTTTTTTAATCAGAGTTTTATCTTTTATGACCGTTAGCAAAAACTTTTATCATTGATGATTCCTATAATATCTTGAATGTTCTCATGTCTGTACCATTTCAGATAAACTGTGCACAAAACTGGTGTTAATGCATTTCAACATCCCACTACTGTTCAGTAGTGTATTAATGTTTACAGCTGTCAGTGTTTTGGTTTTTAATACCAAAATCATATTAGGAATGACAACGTTTAGGACCAAGTGGGACATTAAAAACTCTATCAAACATTTGGGTTCAATTTGGCACGTGATACCTCTAGCAAATATCTGTTCATTTCACCCAGTTATTAATCTTctgatatatatatgtattgtatgTTATTATAGTTGTAGGTTTTATAAAATCATCTCTTACTGTACAGGTTTATATTGATCATGTACAATGATTGCAAAAAtccgatttttaaaaaaataaaaatgtatcaatGAAAA
>TCONS_00001969
GGCCATTCAGAGCCATTGTAGACCTCTTATATGTTGTTATTGTTTCTGAAGGAAATGTGAGTTTGTTTCTGTGTGTCTCTTTTCTTAGATGTTTCAGATTAAAAAGATTTGCTGTATAGGCGCTGGGTATGTTGGTGGTCCAACTTGTAGTGTCATTGCCAGCATGTGTCCTGAGATCACGGTAACAGTGGTGGATGTTAATGAATCCCGGATCAAAGCCTGGAACTCTGATACACTACCCATttatgagcCGGGCCTGAATGAAGTGGTGTTGTCTTGTCGCGGGAAGAACCTCTTCTTCTCCACAGATATAGACTCTGCCATTAAAGAAGCTGATTTGGTCTTCATTTCAGTAAACACCCCAACTAAGACGTACGGTATGGGCAAAGGGCGCGCTGCTGATCTGAAGTTTATTGAGGCATGTGCCCGGCGGATTGTAGAGGTGTCAGACGGGTATAAAATCGTTACAGAGAAGAGCACAGTGCCAGTTCGTGCAGCTGAGAGCATACGCAGGATATTTGATGCCAATACCAAACCCAGCCTTAATCTacagGTTCTCTCTAACCCAGAGTTCCTTGCAGAGGGTACGGCAGTAAAGGACCTTAAAGAGCCAGACCGCGTCTTGATTGGTGGAGATGAGACTCCGGAGGGTCAAAGGGCTATCAGTGCTCTCTGTGCAGTTTATGAGCACTGGGTCCCTAAAACACGCATCATCACCACCAACACCTGGTcctctgaactttctaaactgGCAGCAAATGCGTTCCTGGCTCAGCGCATCAGCAGTATAAACTCCATCTCTGCGCTGTGTGAATCCACTGGTGCTGATGTGGAGGAGGTGGCCAGAGCCATTGGCATGGACCAGCGAATTGGCAGCAAGTTCCTCAAAGCCAGCGTCGGATTTGGAGGAAGTTGTTTTCAGAAGGATGTGCTGAATTTGGTTTACCTCTGTGAAGCACTGAATCTACCAGAGGTTGCTTCATACTGGCAGCAGGTGATTGACATGAATGAATATCAGAGAAAGAGATTCGCCTGTCGGATCATTGACTGCCTGTTTAACACGGTTACAGGGAAGAAAATCGCCTTGTTGGGTTTCTCCTTCAAGAAAGACACGGGAGACACCAGAGAGTCGTCCAGTATTTACATTTCAAAGTATTTGATGGACGAAGGAGCCAAGCTGCATATTTATGACCCTAAAGTACTGAAAGAGCAGATAATCCAGGACCTGTCTCAACCCGGCATCTCCGGAGACAATCCagaaagagTGTCTGATCTTGTAACAGTGACGGTTGACCCCTATGAGGCCTGTGAAAGTGCACATGCTCTGGTCATCTGTACAGAGTGGGATATGTTTAAGgacCTGGATTATGAGAAAATATATCACAAGATGTTGAAACCAGCGTTCATTTTTGATGGACGACGAGTCCTGGATCATCTGCATACCCAACTACAAAACGTTGGCTTTCAGatcgagaccatcGGTAAGAAGGTGATGACACGAATCCCCTTCACAACCTCTGGAGGAGTACCACGAATCACTGAACCACCAGTAAAGAAATCCAAAGCCTGAGGCACAGCTCATCGTCCACACCACAC

Function

symbol description
ugdh Predicted to enable NAD binding activity and UDP-glucose 6-dehydrogenase activity. Acts upstream of or within atrioventricular valve formation; determination of left/right symmetry; and positive regulation of signal transduction. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including axis; head; heart tube; mesoderm; and vestibuloauditory system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 84. Orthologous to human UGDH (UDP-glucose 6-dehydrogenase).

GO:

id name namespace
GO:0090263 positive regulation of canonical Wnt signaling pathway biological_process
GO:0007507 heart development biological_process
GO:0003188 heart valve formation biological_process
GO:0003190 atrioventricular valve formation biological_process
GO:0045880 positive regulation of smoothened signaling pathway biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0006024 glycosaminoglycan biosynthetic process biological_process
GO:0005829 cytosol cellular_component
GO:0005634 nucleus cellular_component
GO:0016491 oxidoreductase activity molecular_function
GO:0003979 UDP-glucose 6-dehydrogenase activity molecular_function
GO:0051287 NAD binding molecular_function
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor molecular_function

KEGG:

id description
ko00040 Pentose and glucuronate interconversions
ko00053 Ascorbate and aldarate metabolism
ko00520 Amino sugar and nucleotide sugar metabolism
ko00541 O-Antigen nucleotide sugar biosynthesis

ZFIN:

id description
ZDB-GENE-011022-1 Predicted to enable NAD binding activity and UDP-glucose 6-dehydrogenase activity. Acts upstream of or within atrioventricular valve formation; determination of left/right symmetry; and positive regulation of signal transduction. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including axis; head; heart tube; mesoderm; and vestibuloauditory system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 84. Orthologous to human UGDH (UDP-glucose 6-dehydrogenase).

Ensembl:

ensembl_id ENSDARG00000019838

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001968 False 2589 mRNA 0.43 12 23283532 23294753
TCONS_00001969 True 1596 mRNA 0.47 11 23284138 23293261

Neighbor

gene id symbol gene type direction distance location
XLOC_001220 rfc1 coding downstream 9028 23243093 ~ 23274504 (-)
XLOC_001219 adgrl3.1 coding downstream 125949 22943551 ~ 23157583 (-)
XLOC_001218 SMIM18 coding downstream 422184 22857753 ~ 22861348 (-)
XLOC_001217 qdprb1 coding downstream 432051 22845225 ~ 22851481 (-)
XLOC_001216 ldb2b coding downstream 448708 22805398 ~ 22834824 (-)
XLOC_001222 smim14 coding upstream 2870 23297623 ~ 23308308 (-)
XLOC_001223 pds5a coding upstream 28249 23323002 ~ 23370618 (-)
XLOC_001224 NA coding upstream 122162 23416915 ~ 23436608 (-)
XLOC_001225 NA coding upstream 150732 23445485 ~ 23447300 (-)
XLOC_001226 fam184b coding upstream 211772 23506525 ~ 23557877 (-)
XLOC_001211 FP245458.1 non-coding downstream 608919 22663723 ~ 22674613 (-)
XLOC_001205 CR388092.1 non-coding downstream 1091465 22191952 ~ 22192067 (-)
XLOC_001204 NA non-coding downstream 1282482 21999781 ~ 22001050 (-)
XLOC_001199 CR786570.1 non-coding downstream 1603054 21680364 ~ 21680478 (-)
XLOC_001189 BX323083.5 non-coding downstream 2267602 21010689 ~ 21015930 (-)
XLOC_001229 NA non-coding upstream 457200 23751953 ~ 23783769 (-)
XLOC_001230 NA non-coding upstream 613964 23908717 ~ 23911006 (-)
XLOC_001234 NA non-coding upstream 1307579 24602332 ~ 24606762 (-)

Expression


Co-expression Network