XLOC_002206 (dlg2)


Basic Information

Item Value
gene id XLOC_002206
gene name dlg2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 29431529 ~ 29705509 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004236
aACAGGCCTCCAGCGGTACAGGGCTCCCAGCACCAAAGCCACTCTCCAGCATGTATGAACCCGGCCCTGATGAGCTCCCCCTGGGTGAGACAGAAACACGGGGGCCGCGCCATACCAAATCGTCTCTGTCTCTCCACAACTGATTCGCCACACTCTTACCGGTATCAGGACGATGATTCCCCTCCTCCTGAACATAGCTTTCCTCGGCTCACCAATGAAGTTCGAGCGCCGGAGTTGGTGCACGTGTCGGAGAAAAACCTCTCAGAAATCGAGAATGTGCATGGTTATGTTTCCCACTCTCACATTTCACCACTTAAGGCAAGTCCTGCTCCAATTATTGTCAACACGGACACTTTGGAATCTGTACCATACGTAAATGGAAcagaaattgaatatgaatttgaAGAGATTACATTAGAGCGGGGTAACTCAGGGTTGGGGTTTAGTATAGCAGGCGGCACAGATAACCCTCACATTGGCGATGATCCCGGAATCTTCATCACAAAAATCATTCCTGGGGGAGCAGCGGCTGAAGACGGCAGACTCAGAGTCAATGACTGTATTTTGCGAGTGAACGAAAGCGATGTTTCCGAGGTGTCTCACAGTAAAGCAGTGGAGGCTCTGAAAGCGGCCGGATCGATTGTGAGGCTCTATGTTCGCAGGAGGAGACCGATGCTGGAGACCGTCACCGAAATCAAACTCATAAAAGGACCAAAAGGGCTCGGCTTCAGTATTGCAGGTGGTGTAGGAAACCAGCACATCCCAGGTGATAACAGCATTTATGTCACTAAAATCATCGACGGAGGTGCTGCACAGAAGGATGGACGGTTACAAGTTGGAGACAGACTGCTTATGGTGAATAACTACACTCTAGAAGAGGTGACGCATGAAGAAGCAGTGGCCATACTGAAGAACACGTCAGATGTGGTTTACCTAAAGGTCGGGAAACCCACTAGTGTCTATCTCTCAGACCCTTATGGGCCGCCTGATATCACACACTCATTCTCACCCGCTATGGAAAATCATATCTCTTCCCCTGGTAATAATGGCACTCTGGAATATAAGTCCAGTCTTCCGCCCATCTCCCCCGGCCGATATTCCCCCCTGCCCAAGCACTTGCTGGGGGAAGAGGACATAAACAGAAATCCCTCATTAGATGAGATGGAAGGTCACAGGTTTGATTCCCAGCACTTCCAGTTGAGGGAGCCCAGGAAGATCGTTCTCCACAAGGGCTCCACCGGACTGGGCTTCAACATCGTGGGAGGAGAAGATGGAGAAGGCATTTTCGTTTCCTTCATCCTGGCTGGAGGGCCTGCCGACCTCAGTGGAGAACTGCGCAGAGGAGACCAGATCCTGTCTGTCAATGGAATCGATCTGCGAGGTGCCACTCACGAACAAGCCGCGGCAGCGCTGAAGGGAGCAGGGCAGACGGTAACCATCATCGCCCAGTACCGGCCCGAGGAGTACGGGCGTTTTGAGGCCAAAATTCATGACTTGCGAGAGCAGATGATGAACCACAGCATGAGTTCTGGATCCGGATCCCTCAGAACCAATCAAAAACGTTCACTCTATGTCAGGGCTCTGTTTGACTATGAGCGAGCGAAGGACAGTGGTCTGCCCAGTCAGGGTCTCAGTTTCCGGTATGGAGACATTCTTCACGTCATTAATGCATCTGATGATGAATGGTGGCAGGCCAGAAGAGTGACGCCCGAGGGGGACAGTGAGGAGATGGGCGTCATTCCCAGCAAGAGGAGGGTTGAAAGAAAAGAGCGAGCTCGTCTGAAGACGGTTAAATTCAACGCAAAACCCGGCAGCCTGGATTCTAAAGGGTCATTCAGTGAAAAACGTAGAAAGAACTTCATCTTTTCACGCAAGTTCCCTTTCTACAAGAACAAGGACGCCGATGAGCAAGACGGCAGTGACTCGGAACGGAGTCAAGAGGAACTGATACTCTCATATGAGCCTGTCATCAGACAAGAGATTAATTACGCCAGACCAGTTATAATCTTGGGGCCCATGAAGGACCGAATCAACGATGACCTCATCTCTGAGTTCCCTGACAAGTTTGGGTCATGTGTGCCACCGGCTAACAGTTCTGATCAAGAAGATACTACCAGACCAAAGCGGGATTATGAAGTGGATGGGAGAGATTATCACTTTATGGCCTCTCGAGAACAGATGGAGAAAGACATCCAAGAGCACAAATTCATTGAGGCTGGACAGTACAATGACAATCTGTACGGAACCAGCGTCCAGTCGGTCAAATACGTGGCTGAGAGGGGTAAGCACTGCATACTTGACGTGTCTGGGAATGCCATAAAACGACTACAAGTAGCACAACTCTACCCCATTGCCATCTTTATAAAGCCTAGATCCATTGAGTCCTTAATGGAAATGAATAAGAGGTTGACAGAGGAACAGGCCAAAAAGACATACGACCGTGCCATGAAACTGGAGCAGGAGTTTGGCGAGTACTTCACAGCGCTGGTTCAAGGAGACACACTAGAGGACATTTATAACCAGTGTAAGATGGTGATAGAGGAACAGTCTGGACCTTACATCTGGATTCCCTCAAAAGAAAAACTATAAAAAGTCACCTTACTCTGGCAGGGACCTTGGACtgcaaaaaagaagaagaaaaaaaaacataggaataatttgtaatataatataaattattattatggcaATGTTTATTGTTAACTCTTAcagtgatttttttgtttgtttgtttatttatttattttacgttGCTTTTTTCACTTTCAATATGAATGTTCCTGAATGT
>TCONS_00004238
GGAGTCAAGAGGAACTGATACTCTCATATGAGCCTGTCATCAGACAAGAGATTAATTACGCCAGACCAGTTATAATCTTGGGGCCCATGAAGGACCGAATCAACGATGACCTCATCTCTGAGTTCCCTGACAAGTTTGGGTCATGTGTGCCACATACTACCAGACCAAAGCGGGATTATGAAGTGGATGGGAGAGATTATCACTTTATGGCCTCTCGAGAACAGATGGAGAAAGACATCCAAGAGCACAAATTCATTGAGGCTGGACAGTACAATGACAATCTGTACGGAACCAGCGTCCAGTCGGTCAAATACGTGGCTGAGAGGGGTAAGCACTGCATACTTGACGTGTCTGGGAATGCCATAAAACGACTACAAGTAGCACAACTCTACCCCATTGCCATCTTTATAAAGCCTAGATCCATTGAGTCCTTAATGGAAATGAATAAGAGGTTGACAGAGGAACAGGCCAAAAAGACATACGACCGTGCCATGAAACTGGAGCAGGAGTTTGGCGAGTACTTCACAGCGCTGGTTCAAGGAGACACACTAGAGGACATTTATAACCAGTGTAAGATGGTGATAGA

Function

symbol description
dlg2 Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; negative regulation of phosphatase activity; and receptor clustering. Predicted to be located in several cellular components, including axon; perikaryon; and synapse. Predicted to be active in several cellular components, including basolateral plasma membrane; neuromuscular junction; and postsynaptic density membrane. Is expressed in nervous system and neural tube. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2).

GO:

id name namespace
GO:0010923 negative regulation of phosphatase activity biological_process
GO:0098609 cell-cell adhesion biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0097120 receptor localization to synapse biological_process
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity biological_process
GO:0043113 receptor clustering biological_process
GO:0009790 embryo development biological_process
GO:0042995 cell projection cellular_component
GO:0098839 postsynaptic density membrane cellular_component
GO:0043005 neuron projection cellular_component
GO:0030424 axon cellular_component
GO:0031594 neuromuscular junction cellular_component
GO:0045202 synapse cellular_component
GO:0005886 plasma membrane cellular_component
GO:0008328 ionotropic glutamate receptor complex cellular_component
GO:0043204 perikaryon cellular_component
GO:0030054 cell junction cellular_component
GO:0016020 membrane cellular_component
GO:0016323 basolateral plasma membrane cellular_component

KEGG:

id description
ko04390 Hippo signaling pathway
ko04530 Tight junction
ko05165 Human papillomavirus infection
ko01009 Protein phosphatases and associated proteins

ZFIN:

id description
ZDB-GENE-050221-3 Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; negative regulation of phosphatase activity; and receptor clustering. Predicted to be located in several cellular components, including axon; perikaryon; and synapse. Predicted to be active in several cellular components, including basolateral plasma membrane; neuromuscular junction; and postsynaptic density membrane. Is expressed in nervous system and neural tube. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2).

Ensembl:

ensembl_id ENSDARG00000099323

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004236 False 2788 mRNA 0.48 23 29431529 29705509
TCONS_00004238 True 586 mRNA 0.46 6 29698467 29705261

Neighbor

gene id symbol gene type direction distance location
XLOC_002205 FP102896.1 coding upstream 98354 29333059 ~ 29333175 (+)
XLOC_002204 crebzf coding upstream 162806 29265463 ~ 29268723 (+)
XLOC_002203 sytl2a coding upstream 167506 29259882 ~ 29264023 (+)
XLOC_002202 picalma coding upstream 206364 29137482 ~ 29225165 (+)
XLOC_002201 NA coding upstream 339928 29091237 ~ 29091601 (+)
XLOC_002208 hyou1 coding downstream 64611 29770120 ~ 29791466 (+)
XLOC_002209 h2ax1 coding downstream 111172 29816681 ~ 29817589 (+)
XLOC_002210 BX120005.2 coding downstream 135216 29840725 ~ 29848513 (+)
XLOC_002211 hspa8 coding downstream 143988 29849497 ~ 29887864 (+)
XLOC_002212 BX120005.5 coding downstream 145063 29850572 ~ 29850667 (+)
XLOC_002199 NA non-coding upstream 976444 28442909 ~ 28455085 (+)
XLOC_002196 CU207388.1 non-coding upstream 1178734 28252678 ~ 28252795 (+)
XLOC_002195 NA non-coding upstream 1185109 28203764 ~ 28246420 (+)
XLOC_002213 BX120005.4 non-coding downstream 145491 29851000 ~ 29851095 (+)
XLOC_002214 BX120005.1 non-coding downstream 146638 29852147 ~ 29852242 (+)
XLOC_002215 NA non-coding downstream 188117 29893626 ~ 29911696 (+)
XLOC_002217 BX957285.1 non-coding downstream 1030639 30736148 ~ 30736268 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00016297 dlg2 coding CM030122.1 CM030122.1 15087879 ~ 15105018 (+)