| Item | Value |
|---|---|
| gene id | XLOC_022264 |
| gene name | ikbkg |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007134.7 |
| NCBI id | CM002907.2 |
| chromosome length | 46223584 |
| location | 18574221 ~ 18597709 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| ikbkg | Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity. Acts upstream of or within I-kappaB phosphorylation and positive regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to be part of IkappaB kinase complex. Predicted to be active in cytoplasm and nucleus. Is expressed in periderm. Human ortholog(s) of this gene implicated in Behcet's disease; Bloch-Sulzberger syndrome; immunodeficiency 33; and learning disability. Orthologous to human IKBKG (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma). |
| id | name | namespace |
|---|---|---|
| GO:0016070 | RNA metabolic process | biological_process |
| GO:0006351 | transcription, DNA-templated | biological_process |
| GO:0007252 | I-kappaB phosphorylation | biological_process |
| GO:0097659 | nucleic acid-templated transcription | biological_process |
| GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | biological_process |
| GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | biological_process |
| GO:0044260 | cellular macromolecule metabolic process | biological_process |
| GO:0043170 | macromolecule metabolic process | biological_process |
| GO:0032774 | RNA biosynthetic process | biological_process |
| GO:0016310 | phosphorylation | biological_process |
| GO:0044424 | obsolete intracellular part | cellular_component |
| GO:0017119 | Golgi transport complex | cellular_component |
| GO:0005622 | intracellular anatomical structure | cellular_component |
| GO:0005634 | nucleus | cellular_component |
| GO:0099023 | vesicle tethering complex | cellular_component |
| GO:0043226 | organelle | cellular_component |
| GO:0043227 | membrane-bounded organelle | cellular_component |
| GO:0043229 | intracellular organelle | cellular_component |
| GO:0043231 | intracellular membrane-bounded organelle | cellular_component |
| GO:0008385 | IkappaB kinase complex | cellular_component |
| GO:0005737 | cytoplasm | cellular_component |
| GO:0042393 | histone binding | molecular_function |
| GO:0070530 | K63-linked polyubiquitin modification-dependent protein binding | molecular_function |
| GO:0016740 | transferase activity | molecular_function |
| GO:0005515 | protein binding | molecular_function |
| GO:0046872 | metal ion binding | molecular_function |
| GO:0016301 | kinase activity | molecular_function |
| id | description |
|---|---|
| ko04010 | MAPK signaling pathway |
| ko04014 | Ras signaling pathway |
| ko04064 | NF-kappa B signaling pathway |
| ko04668 | TNF signaling pathway |
| ko04151 | PI3K-Akt signaling pathway |
| ko04210 | Apoptosis |
| ko04620 | Toll-like receptor signaling pathway |
| ko04621 | NOD-like receptor signaling pathway |
| ko04622 | RIG-I-like receptor signaling pathway |
| ko04623 | Cytosolic DNA-sensing pathway |
| ko04625 | C-type lectin receptor signaling pathway |
| ko04660 | T cell receptor signaling pathway |
| ko04658 | Th1 and Th2 cell differentiation |
| ko04659 | Th17 cell differentiation |
| ko04657 | IL-17 signaling pathway |
| ko04662 | B cell receptor signaling pathway |
| ko04062 | Chemokine signaling pathway |
| ko04920 | Adipocytokine signaling pathway |
| ko04380 | Osteoclast differentiation |
| ko05200 | Pathways in cancer |
| ko05208 | Chemical carcinogenesis - reactive oxygen species |
| ko05203 | Viral carcinogenesis |
| ko05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
| ko05212 | Pancreatic cancer |
| ko05221 | Acute myeloid leukemia |
| ko05220 | Chronic myeloid leukemia |
| ko05215 | Prostate cancer |
| ko05222 | Small cell lung cancer |
| ko05166 | Human T-cell leukemia virus 1 infection |
| ko05170 | Human immunodeficiency virus 1 infection |
| ko05161 | Hepatitis B |
| ko05160 | Hepatitis C |
| ko05171 | Coronavirus disease - COVID-19 |
| ko05164 | Influenza A |
| ko05162 | Measles |
| ko05168 | Herpes simplex virus 1 infection |
| ko05163 | Human cytomegalovirus infection |
| ko05167 | Kaposi sarcoma-associated herpesvirus infection |
| ko05169 | Epstein-Barr virus infection |
| ko05165 | Human papillomavirus infection |
| ko05120 | Epithelial cell signaling in Helicobacter pylori infection |
| ko05130 | Pathogenic Escherichia coli infection |
| ko05132 | Salmonella infection |
| ko05131 | Shigellosis |
| ko05135 | Yersinia infection |
| ko05145 | Toxoplasmosis |
| ko05142 | Chagas disease |
| ko05340 | Primary immunodeficiency |
| ko05010 | Alzheimer disease |
| ko05417 | Lipid and atherosclerosis |
| ko05418 | Fluid shear stress and atherosclerosis |
| ko01523 | Antifolate resistance |
| ko01001 | Protein kinases |
| id | description |
|---|---|
| ZDB-GENE-050327-68 | Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity. Acts upstream of or within I-kappaB phosphorylation and positive regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to be part of IkappaB kinase complex. Predicted to be active in cytoplasm and nucleus. Is expressed in periderm. Human ortholog(s) of this gene implicated in Behcet's disease; Bloch-Sulzberger syndrome; immunodeficiency 33; and learning disability. Orthologous to human IKBKG (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma). |
| ensembl_id | ENSDARG00000017037 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00043952 | False | 830 | lncRNA | 0.42 | 2 | 18574221 | 18578522 |
| TCONS_00043953 | False | 2448 | mRNA | 0.48 | 13 | 18574274 | 18597704 |
| TCONS_00043954 | False | 1812 | mRNA | 0.50 | 13 | 18574719 | 18595020 |
| TCONS_00043955 | False | 1769 | mRNA | 0.50 | 12 | 18574719 | 18595025 |
| TCONS_00043956 | True | 2054 | mRNA | 0.50 | 14 | 18574721 | 18597709 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_022263 | ssr4 | coding | downstream | 1536 | 18569291 ~ 18572685 (-) |
| XLOC_022262 | sephs2 | coding | downstream | 5699 | 18558209 ~ 18568522 (-) |
| XLOC_022261 | NA | coding | downstream | 158349 | 18386787 ~ 18415872 (-) |
| XLOC_022260 | NA | coding | downstream | 189053 | 18382297 ~ 18385168 (-) |
| XLOC_022259 | hsd17b10 | coding | downstream | 192860 | 18372048 ~ 18381361 (-) |
| XLOC_022265 | zgc:158296 | coding | upstream | 5478 | 18603187 ~ 18609475 (-) |
| XLOC_022266 | CT027756.2 | coding | upstream | 12307 | 18610016 ~ 18611010 (-) |
| XLOC_022267 | CT027756.1 | coding | upstream | 13418 | 18611127 ~ 18612421 (-) |
| XLOC_022268 | arhgap4b | coding | upstream | 18283 | 18615992 ~ 18668836 (-) |
| XLOC_022269 | zgc:103759 | coding | upstream | 104807 | 18702516 ~ 18707568 (-) |
| XLOC_022256 | NA | non-coding | downstream | 499802 | 18073715 ~ 18074419 (-) |
| XLOC_022255 | dre-mir-135c-2 | non-coding | downstream | 510922 | 18063173 ~ 18063299 (-) |
| XLOC_022251 | NA | non-coding | downstream | 688370 | 17881023 ~ 17885851 (-) |
| XLOC_022270 | trpc4apb | non-coding | upstream | 161833 | 18759542 ~ 18777957 (-) |
| XLOC_022272 | NA | non-coding | upstream | 271508 | 18869217 ~ 18898522 (-) |
| XLOC_022273 | NA | non-coding | upstream | 306965 | 18904674 ~ 18913159 (-) |
| species | gene id | symbol | gene type | chromosome | NCBI id | location |
|---|---|---|---|---|---|---|
| grasscarp (Ctenopharyngodon idella) | CI01000001_05295894_05308912 | SSR4, SSRD, IKBKG | coding | CI01000001 | null | 5295523 ~ 5308986 (-) |