Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_025201 |
| gene name | stat5a |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007114.7 |
| NCBI id | CM002887.2 |
| chromosome length | 62628489 |
| location | 17251542 ~ 17331919 (+) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| stat5a | Enables DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within several processes, including hemopoiesis; positive regulation of myeloid cell differentiation; and receptor signaling pathway via JAK-STAT. Predicted to be located in cytoplasm and nucleus. Is expressed in adaxial cell and liver. Human ortholog(s) of this gene implicated in growth hormone insensitivity syndrome with immune dysregulation 1 and growth hormone insensitivity syndrome with immune dysregulation 2. Orthologous to human STAT5A (signal transducer and activator of transcription 5A) and STAT5B (signal transducer and activator of transcription 5B). |
| id | name | namespace |
|---|---|---|
| GO:0030098 | lymphocyte differentiation | biological_process |
| GO:0019221 | cytokine-mediated signaling pathway | biological_process |
| GO:0006355 | regulation of transcription, DNA-templated | biological_process |
| GO:0042127 | regulation of cell population proliferation | biological_process |
| GO:0006952 | defense response | biological_process |
| GO:0060397 | growth hormone receptor signaling pathway via JAK-STAT | biological_process |
| GO:0007259 | receptor signaling pathway via JAK-STAT | biological_process |
| GO:0048821 | erythrocyte development | biological_process |
| GO:0030218 | erythrocyte differentiation | biological_process |
| GO:0048589 | developmental growth | biological_process |
| GO:0043434 | response to peptide hormone | biological_process |
| GO:0045639 | positive regulation of myeloid cell differentiation | biological_process |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | biological_process |
| GO:0007165 | signal transduction | biological_process |
| GO:0005829 | cytosol | cellular_component |
| GO:0005634 | nucleus | cellular_component |
| GO:0005737 | cytoplasm | cellular_component |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | molecular_function |
| GO:0003677 | DNA binding | molecular_function |
| GO:0003700 | DNA-binding transcription factor activity | molecular_function |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | molecular_function |
| id | description |
|---|---|
| ko04012 | ErbB signaling pathway |
| ko04630 | JAK-STAT signaling pathway |
| ko04217 | Necroptosis |
| ko04658 | Th1 and Th2 cell differentiation |
| ko04659 | Th17 cell differentiation |
| ko04917 | Prolactin signaling pathway |
| ko04935 | Growth hormone synthesis, secretion and action |
| ko05200 | Pathways in cancer |
| ko05207 | Chemical carcinogenesis - receptor activation |
| ko05203 | Viral carcinogenesis |
| ko05221 | Acute myeloid leukemia |
| ko05220 | Chronic myeloid leukemia |
| ko05223 | Non-small cell lung cancer |
| ko05166 | Human T-cell leukemia virus 1 infection |
| ko05161 | Hepatitis B |
| ko05162 | Measles |
| ko04933 | AGE-RAGE signaling pathway in diabetic complications |
| ko03000 | Transcription factors |
| id | description |
|---|---|
| ZDB-GENE-030820-2 | Enables DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within several processes, including hemopoiesis; positive regulation of myeloid cell differentiation; and receptor signaling pathway via JAK-STAT. Predicted to be located in cytoplasm and nucleus. Is expressed in adaxial cell and liver. Human ortholog(s) of this gene implicated in growth hormone insensitivity syndrome with immune dysregulation 1 and growth hormone insensitivity syndrome with immune dysregulation 2. Orthologous to human STAT5A (signal transducer and activator of transcription 5A) and STAT5B (signal transducer and activator of transcription 5B). |
| ensembl_id | ENSDARG00000019392 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00049762 | False | 2612 | mRNA | 0.51 | 19 | 17251542 | 17331898 |
| TCONS_00049763 | True | 880 | mRNA | 0.49 | 6 | 17314997 | 17331919 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_025200 | stat3 | coding | upstream | 144097 | 17030665 ~ 17107445 (+) |
| XLOC_025199 | cavin1a | coding | upstream | 239202 | 16976095 ~ 17012340 (+) |
| XLOC_025198 | atp6v0a1a | coding | upstream | 278417 | 16922226 ~ 16973125 (+) |
| XLOC_025197 | BX470185.1 | coding | upstream | 368238 | 16874401 ~ 16883304 (+) |
| XLOC_025196 | stk17al | coding | upstream | 378633 | 16841942 ~ 16872909 (+) |
| XLOC_025202 | si:ch211-210g13.5 | coding | downstream | 14583 | 17346502 ~ 17523082 (+) |
| XLOC_025203 | CU207238.1 | coding | downstream | 63320 | 17395239 ~ 17461885 (+) |
| XLOC_025204 | hcrt | coding | downstream | 205433 | 17537352 ~ 17541448 (+) |
| XLOC_025205 | kcnh4a | coding | downstream | 215613 | 17547532 ~ 17604109 (+) |
| XLOC_025206 | rab5c | coding | downstream | 283680 | 17615599 ~ 17651899 (+) |
| XLOC_025429 | BX649540.1 | misc | downstream | 12916820 | 30248739 ~ 30249036 (+) |
| XLOC_025188 | CR388224.1 | non-coding | upstream | 878415 | 16373012 ~ 16373127 (+) |
| XLOC_025185 | NA | non-coding | upstream | 1010202 | 16186593 ~ 16241340 (+) |
| XLOC_025184 | NA | non-coding | upstream | 1090083 | 16153224 ~ 16161459 (+) |
| XLOC_025183 | CR387933.1 | non-coding | upstream | 1195810 | 16055009 ~ 16055732 (+) |
| XLOC_025215 | NA | non-coding | downstream | 708694 | 18040613 ~ 18061783 (+) |
| XLOC_025218 | NA | non-coding | downstream | 857690 | 18189609 ~ 18197126 (+) |
| XLOC_025227 | NA | non-coding | downstream | 1338905 | 18670824 ~ 18672291 (+) |
| XLOC_025229 | AL772362.2 | non-coding | downstream | 1439609 | 18771528 ~ 18788485 (+) |
